Nitrocontin 2.6mg Tablet 30'S

Introduction About NITROCONTIN 2.6MG TABLET

Nitrocontin 2.6mg Tablet (Nitroglycerin Controlled Release) is a medicine that supports heart health by easing chest discomfort linked with angina pectoris. Belonging to the vasodilators group, this tablet works by relaxing and widening blood vessels, which helps improve blood flow to the heart and reduces the heart's workload. Its controlled-release formulation ensures a steady effect over time, helping to manage episodes of chest pain commonly experienced due to reduced oxygen supply caused by coronary artery disease.

By aiding smooth blood circulation and lessening pressure on the heart, Nitrocontin 2.6mg Tablet contributes to maintaining comfort during physical activity or stress. It is recommended to use this medicine consistently as advised by your healthcare provider to gain optimal support for heart function.

Nitrocontin 2.6 Tablet CR should be taken exactly as directed by your doctor. It can be taken with or without food, ideally at the same time each day for consistent effect. Avoid exceeding the prescribed dose, as higher amounts may cause unwanted effects.

Over time, your body may develop tolerance to this medicine, meaning the same dose may become less effective. To help reduce this, it is important to follow a strict dosing schedule without missing doses or making unsupervised changes. Always consult your healthcare provider if you notice reduced effectiveness or have any concerns about your dosage plan.

Common side effects of Nitrocontin 2.6mg Tablet include headaches, which can sometimes be intense, dizziness, lightheadedness, flushing, low blood pressure, spinning sensations, drowsiness, nausea, and feelings of weakness. Drinking plenty of fluids and avoiding alcohol may help ease headaches. Lightheadedness can increase the risk of falls, so caution is advised during activities that require balance. There are rarer side effects, some of which may be serious. It is important to read the medicine leaflet thoroughly and consult your doctor to ensure safe use. Always report any unusual or persistent symptoms to your healthcare provider promptly.

Do not use Nitrocontin 2.6mg Tablet if you are currently taking medicines for pulmonary hypertension (high blood pressure in the lungs), erectile dysfunction, or if you have anemia or glaucoma (increased pressure in the eye). Always inform your doctor about any existing health conditions and all other medications you are using. It is advisable to avoid alcohol while taking this medicine, as it can increase certain side effects. If you experience dizziness, refrain from driving or operating machinery until you feel stable. If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before starting this medicine to ensure safety for you and your baby.

Uses Of NITROCONTIN 2.6MG TABLET

• Angina pectoris (Chest pain or Chest discomfort)

Benefits of NITROCONTIN 2.6MG TABLET

1. Supports Heart Comfort: Nitrocontin 2.6mg Tablet helps ease chest discomfort related to angina by enhancing blood flow to the heart muscles.
2. Relaxes Blood Vessels: This medicine widens and relaxes blood vessels, reducing the effort your heart needs to pump blood.
3. Provides Extended Effect: Its controlled-release design delivers a steady effect throughout the day, ensuring continuous support.
4. Facilitates Physical Activity: By improving blood circulation, it helps maintain comfort during everyday activities and exercise.
5. Enhances Oxygen Supply: Nitrocontin improves oxygen delivery to the heart, supporting overall heart muscle function.

How NITROCONTIN 2.6MG TABLET Works

How Does Nitrocontin 2.6mg Tablet Work?

Nitrocontin 2.6mg Tablet gradually releases nitroglycerin, which relaxes and widens blood vessels. This process reduces the strain on the heart by improving blood flow and lowering the heart's workload, helping to ease chest discomfort associated with angina.

Mechanism of Action: Nitrocontin 2.6mg

The active component, nitroglycerin, converts to nitric oxide (NO) within the body. Nitric oxide activates enzymes that cause relaxation of smooth muscles in the blood vessels. This vasodilation effect increases blood flow through veins and arteries, enhancing oxygen delivery to the heart muscle.

How Nitroglycerin Supports Heart Health

By expanding blood vessels, Nitrocontin helps reduce pressure within the heart and improves circulation. This promotes better oxygen supply to heart tissues and supports more efficient heart function during daily activities.

Understanding Vasodilation with Nitrocontin

Vasodilation occurs when blood vessel walls relax, allowing vessels to widen. Nitrocontin’ s controlled-release formulation ensures sustained vasodilation, maintaining steady blood circulation and reduced cardiac workload over time.

Key Science Behind Nitrocontin 2.6mg Tablet

Nitroglycerin’ s conversion to nitric oxide triggers a series of cellular reactions, leading to decreased calcium in smooth muscle cells and resulting in vessel relaxation. This scientific process underlies Nitrocontin’ s ability to support cardiovascular function by improving blood flow and easing heart strain.

How to use NITROCONTIN 2.6MG TABLET

How to Take Nitrocontin 2.6mg Tablet

• Take Nitrocontin 2.6mg Tablet exactly as directed by your doctor.
• Swallow the tablet whole with a glass of water.
• It can be taken with or without food, preferably at the same time each day to maintain steady effects.

Recommended Dosage and Schedule

• Follow the prescribed dose carefully.
• Typically, adults take one tablet twice daily, spaced evenly throughout the day.
• Do not exceed the recommended dose as it may cause unwanted side effects.
• Consistency in timing helps maintain effectiveness.

Directions for Safe Use

• Do not crush, chew, or break the tablet.
• Stick to the prescribed schedule to avoid tolerance, where the medicine may become less effective.
• Inform your healthcare provider about any other medicines or health conditions before taking Nitrocontin.

Tips for Taking Nitrocontin 2.6mg Tablet

• Take the tablet with plenty of water, avoid alcohol as it may increase side effects, and rest if you feel dizzy or lightheaded.
• Regular check-ups help your doctor monitor your progress and adjust dosage if needed.

Special Instructions for Elderly

• Elderly patients should use Nitrocontin with caution.
• Dizziness and low blood pressure may be more pronounced, so it’s advisable to sit or lie down when taking the medicine to reduce falls.
• Always follow your doctor’s guidance carefully.

What if I forgot to take NITROCONTIN 2.6MG TABLET

• If you miss a dose, take it as soon as you remember.
• If it is near the time for your next dose, skip the missed one and continue with your regular schedule.
• Avoid taking a double dose to compensate.

Side Effects Of NITROCONTIN 2.6MG TABLET

Common:

• Headache
• Dizziness
• Lightheadedness
• Flushing
• Low blood pressure
• Spinning sensations
• Drowsiness
• Nausea
• Feelings of weakness

When to consult your doctor?

• Fainting or severe dizziness
• Irregular or rapid heartbeat
• Difficulty in breathing or shortness of breath
• Worsening chest pain
• Allergic reactions symptoms such as swelling of the face, lips, tongue, or throat, along with rash or hives
• Sudden changes in vision or blindness in one eye
• Low oxygen levels symptoms such as bluish discoloration of lips, fingers, or toes
• Stroke symptoms such as sudden weakness, slurred speech, or loss of coordination

How To Manage Side Effects

Warning & Precautions

Pregnancy

Use with Caution

Nitrocontin 2.6mg Tablet should be used with caution in pregnant women. Consult your doctor before taking it. 

Breastfeeding

Use with Caution

Nitrocontin 2.6mg Tablet should be used with caution in breastfeeding women.  Consult your doctor before taking it.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel dizziness or lightheadedness after taking Nitrocontin 2.6mg Tablet.  

Alcohol

Contraindicated

Avoid consumption of alcohol during the management with Nitrocontin 2.6mg Tablet as it may increase some effects of the medicine. 

Kidney

Use with Caution

Nitrocontin 2.6mg Tablet should be taken with caution in patients with severe kidney disease. Consult your doctor before taking it.

Liver

Use with Caution

Nitrocontin 2.6mg Tablet should be used with caution in patients with severe liver disease. Consult your doctor before taking it.

Allergy

Contraindicated

Do not take Nitrocontin 2.6mg Tablet if you are allergic to Nitroglycerin or any other components of this medicine.

Heart Disease

Consult your doctor

Nitrocontin 2.6mg Tablet is not recommended for use in patients having heart diseases such as hypertrophic obstructive cardiomyopathy (thickening of heart muscles) and should be used with caution in patients having other heart diseases such as have had a recent heart attack, narrowing of heart valves, inflammation of heart, heart failure or fluid build-up around the heart. Consult your doctor before taking it. 

Use In Pediatrics

Contraindicated

Nitrocontin 2.6mg Tablet is not recommended for use in children. Consult your paediatrician before giving it. 

Use In Geriatrics

Use with Caution

Nitrocontin 2.6mg Tablet should be used with caution in elderly patients. Consult your doctor before taking this medicine.

Other Warnings for NITROCONTIN 2.6MG TABLET

Before taking NITROCONTIN 2.6MG TABLET inform your doctor if you have:

• underactive thyroid gland
• low body temperature
• malnutrition
• abnormally decreased levels of oxygen in blood
• severely low blood pressure
• low blood volume
• conditions that lower the blood volume in the heart
• cerebrovascular diseases (diseases affecting the blood vessels supplying the brain)

Who should not take NITROCONTIN 2.6MG TABLET

NITROCONTIN 2.6MG TABLET is not recommended for use if you:

• have anaemia
• have raised pressure in head
• bleeding on brain
• raised pressure in the eye

Interactions

Drug - Drug interaction

Before taking Nitrocontin 2.6mg Tablet, inform your doctor if you are taking any of the following medicine:

1. PDE-5 Inhibitors (e.g., Sildenafil, Tadalafil, Vardenafil)
   Interaction: Taking Nitrocontin with PDE-5 inhibitors may cause a significant and dangerous drop in blood pressure.
   Effects: Increased risk of severe hypotension, dizziness, fainting, and possible loss of consciousness.
   Management: Avoid concurrent use; inform your doctor if you are prescribed these medications for erectile dysfunction or pulmonary hypertension.
    
2. Other Nitrates (e.g., Isosorbide Dinitrate, Isosorbide Mononitrate)
   Interaction: Combining Nitrocontin with other nitrates enhances the blood pressure-lowering effects.
   Effects: Pronounced hypotension, dizziness, and risk of fainting.
   Management: Use caution and inform your doctor; dose adjustments or alternative therapies may be necessary.
    
3. Antihypertensive Drugs (e.g., Beta-blockers like Metoprolol, Atenolol)
   Interaction: Nitrocontin may increase the blood pressure-lowering effect of antihypertensive drugs.
   Effects: Enhanced hypotension, light-headedness, dizziness especially when standing up quickly.
   Management: Monitor blood pressure regularly and report symptoms to your doctor; dose adjustments may be needed.
    
4. Warfarin (Blood Thinner)
   Interaction: Nitrocontin may interact with warfarin, potentially altering its effect on blood clotting.
   Effects: Altered bleeding risk, either increased bleeding or clotting.
   Management: Inform your healthcare provider; frequent monitoring of INR (clotting time) is recommended.
    
5. Ergotamine (for Migraine)
   Interaction: Nitrocontin may antagonize the vasoconstrictive effects of ergotamine.
   Effects: Reduced effectiveness of migraine management.
   Management: Inform doctor if taking migraine medications; alternative managements may be considered.
    
6. Tricyclic Antidepressants (e.g., Amitriptyline)
   Interaction: Combined use might increase side effects like dizziness and low blood pressure.
   Effects: Dizziness, lightheadedness, fainting risk.
   Management: Use with caution; report any unusual symptoms to your doctor for possible dose adjustment.
    
7. Insulin and Sulfonylureas (e.g., Glibenclamide, Glimepiride)
   Interaction: Nitrocontin may increase the risk of hypoglycemia when taken with insulin or sulfonylureas.
   Effects: Dizziness, sweating, shaking, or fainting due to low blood sugar.
   Management: Inform your doctor; blood sugar levels should be closely monitored and dose adjustments considered.

Drug - Food interaction

1. Grapefruit and Grapefruit Juice
   Interaction: Consuming grapefruit or grapefruit juice while taking Nitrocontin may interfere with the metabolism of the medicine.
   Effects: Increased levels of nitroglycerin in the body, leading to a higher risk of side effects such as dizziness and low blood pressure.
   Management: Avoid grapefruit and grapefruit juice during Nitrocontin management, consult your doctor for any dietary concerns.
    
2. Alcohol
   Interaction: Alcohol can enhance the blood pressure-lowering effect of Nitrocontin.
   Effects: Increased risk of hypotension, dizziness, lightheadedness, and fainting.
   Management: Avoid alcohol consumption while using Nitrocontin to reduce these side effects.
    
3. High-Fat Meals
   Interaction: Eating high-fat foods before taking Nitrocontin may delay the absorption of the medicine.
   Effects: Reduced effectiveness of Nitrocontin and delayed onset of action.
   Management: Take Nitrocontin on an empty stomach or with light, bland foods; avoid heavy, fatty meals around medication time.
    
4. Caffeine-containing Foods and Beverages
   Interaction: Caffeine may counteract the vasodilating effect of Nitrocontin.
   Effects: Reduced effectiveness in relieving chest pain (angina).
   Management: Limit caffeine intake while on Nitrocontin; discuss with your doctor for personalized advice.

Synopsis

More Information

01. How can you effectively incorporate Nitrocontin 2.6mg tablets into your daily routine, what dietary considerations should you follow, and why is regular heart monitoring or diagnostic testing important?

FAQs About NITROCONTIN 2.6MG TABLET

Q: What is Nitrocontin 2.6mg Tablet prescribed for?

A: Nitrocontin 2.6mg Tablet helps manage angina by improving blood flow to the heart, reducing chest pain caused by narrowed blood vessels.

Q: How does Nitrocontin 2.6mg Tablet work in the body?

A: It relaxes and widens blood vessels, easing the heart’s workload and enhancing oxygen supply to the heart muscles.

Q: What is the recommended way to take Nitrocontin 2.6mg Tablet?

A: Take the tablet whole with water, once or twice daily as directed by your doctor. Avoid chewing or crushing it to maintain its effectiveness.

Q: Can I drink alcohol while on Nitrocontin 2.6mg Tablet?

A: Alcohol should be avoided since it can amplify side effects like dizziness and low blood pressure.

Q: What side effects might occur with Nitrocontin 2.6mg Tablet?

A: Common side effects include headache, dizziness, flushing, and nausea. Inform your healthcare provider if these persist.

Q: Is Nitrocontin 2.6mg Tablet suitable for elderly patients?

A: The elderly may need careful dose adjustments due to increased sensitivity to lowering blood pressure effects.

Q: Can Nitrocontin 2.6mg Tablet be combined with erectile dysfunction drugs?

A: Combining Nitrocontin with such medications is not recommended due to the risk of severe blood pressure drops.

Q: What should I do if a dose of Nitrocontin 2.6mg Tablet is missed?

A: Take it as soon as remembered unless it’s near the next scheduled dose. Do not double up doses.

Q: Why is regular heart check-up important during Nitrocontin therapy?

A: Monitoring ensures optimal management of angina symptoms and timely detection of heart condition changes.

Q: Can this medicine be stopped suddenly?

A: It is not advisable to stop Nitrocontin 2.6mg Tablet abruptly as doing so may trigger angina attacks or worsen symptoms. Your doctor may recommend gradually tapering the dose over several weeks to reduce sudden exacerbation of chest pain.

Q: Are there any dietary precautions while taking Nitrocontin 2.6mg Tablet?

A: To ensure safety and effectiveness, avoid alcohol consumption which can increase side effects such as dizziness and low blood pressure. Also, limit intake of high-fat foods and caffeine, as these may affect the absorption and efficacy of the medication. Maintain a heart-healthy diet with low salt and saturated fats and follow your doctor’s dietary advice for managing angina effectively.

References

1. KD. Tripathi. Antianginal and Other Anti-ischaemic Drugs. Essentials of medical pharmacology. Eighth edition. 2019. Page – 588, 589.

2. Panel Donald, P.PageN, Aubrey Carson Clarence, A.Buhr, Paul E.Flinn, Clyde E, Wells Margaret, T.Randall. Stability Study of Nitroglycerin Sublingual Tablets. Science Direct. January 2016. [Accessed 8th October 2025]

3. T Winsor, H J Berger. Oral nitroglycerin as a prophylactic antianginal drug: clinical, physiologic, and statistical evidence of efficacy based on a three-phase experimental design. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. November 1975. [Accessed 8th October 2025]

4. W Schneider, M Kaltenbach, B Stahl, W D Bussmann. Anti-anginal efficacy of oral nitroglycerin. A clinical double-blind study with dose-effect relationships. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. August 1984. [Accessed 8th October 2025]

5. Kyle H. Kim, Connor C. Kerndt, Ghufran Adnan, Derek J. Schaller. Statpearls. Nitroglycerin. NIH National Library of Medicine, National center for biotechnology information. November 202. [Accessed on 8th October 2025]

6. Leeford Healthcare. Caditril 6.4 (Nitroglycerine). [Accessed 8th October 2025]

7. Leeford Healthcare. Caditril 2.6 (Nitroglycerine). [Accessed 8th October 2025]

Useful Diagnostic Tests

• Kidney Function Test (KFT)
• Liver Function Test (LFT)
• Lipid Profile

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 08 Oct 2025 | 03:36 PM(IST)