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Korandil 5mg Tablet 10'S

Angina
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    Introduction About KORANDIL 5MG TABLET

    Korandil 5mg Tablet contains Nicorandil, a medication primarily used to manage angina pectoris (chest pain caused by reduced blood flow to the heart). It works by relaxing the coronary blood vessels, which improves blood flow to the heart and reduces chest pain.

    Korandil 5mg Tablet can be taken with or without food. It should be swallowed whole with water. Take the medication consistently at approximately the same time each day. Your doctor will determine the appropriate dosage and frequency, which may be adjusted over time based on its effectiveness. Do not stop taking it without consulting your doctor, as sudden discontinuation may cause your chest pain to return. To support your heart health, consider making lifestyle changes, such as quitting smoking, reducing alcohol consumption, eating a balanced diet, exercising regularly, and managing stress.

    Common side effect of this medication includes headache, dizziness, flushing, low blood pressure, weakness, nausea, flushing (sense of warmth in the face, ears, neck, and trunk). If any side effects are troubling or persist, consult your doctor.

    Korandil 5mg Tablet may not be suitable for everyone. Inform your doctor if you have a history of low blood pressure or heart failure. Additionally, tell your doctor about all other medications you are taking, as some may interact with or be influenced by this medicine. You should avoid using any erectile dysfunction medications while taking Korandil 5 Tablet. This medication is generally not recommended during pregnancy or breastfeeding.

    Uses Of KORANDIL 5MG TABLET

    • Angina pectoris

    Benefits of KORANDIL 5MG TABLET

    1. Manage angina: Korandil effectively reduces the frequency and severity of angina attacks.
    2. Improves Heart Function: By improving blood flow to the heart, it helps in better cardiac health.
    3. Reduces Blood Pressure: It may assist in lowering high blood pressure, reducing the heart's workload.
    4. Fast-Acting: The medication works quickly to alleviate chest pain during episodes of angina.

    How KORANDIL 5MG TABLET Works

    Korandil 5mg tablet, containing the active ingredient Nicorandil, works by relaxing and widening the blood vessels, particularly in the heart. It acts as both a nitrate and a potassium channel opener. The nitrate component helps to relax the smooth muscles in the blood vessel walls, reducing the heart's workload and improving blood flow. The potassium channel-opening action further relaxes vascular smooth muscle, helping to reduce or relieve angina (chest pain) by ensuring better oxygen delivery to the heart. This combination makes it effective in managing conditions like angina and reducing the frequency of angina attacks.

    How to use KORANDIL 5MG TABLET

    Follow your doctor's instructions regarding the exact dosage. Do not exceed the recommended daily dosage.

    How to Take Korandil 5mg Tablet?

    • Take one tablet once or twice daily with or without food.
    • Swallow the tablet whole with a glass of water. Do not crush or chew the medication.
    • For best results, take the tablet at the same time each day.

    Can I take more than the recommended dose of Korandil 5mg if I do not feel relief from chest pain?

    No, you should not increase your dosage even if you do not feel immediate relief. Taking more than the prescribed amount can lead to serious side effects. If you are experiencing persistent chest pain or discomfort, contact your doctor immediately.

    What if I forgot to take KORANDIL 5MG TABLET

    If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your usual schedule. Never take two doses at once to make up for a missed dose.

    Side Effects Of KORANDIL 5MG TABLET

    Like all medicines, Korandil 5mg Tablet may cause certain side effects in some individuals, although not everybody gets them.

    The most common side effects of taking Korandil 5mg Tablet are:

    • Headache
    • Dizziness
    • Flushing
    • Low blood pressure
    • Weakness
    • Nausea
    • Flushing (sense of warmth in the face, ears, neck, and trunk)

    When to consult your doctor?

    • Serious allergic reaction symptoms such as swelling of the face, lips, tongue, or throat, difficulty breathing
    • Severe dizziness or fainting
    • Cardiovascular problems symptoms such as chest pain, tightness, or discomfort, rapid or irregular heartbeat
    • Severe or persistent headache
    • Gastrointestinal bleeding symptoms such as bleeding from the rectum, blood in vomit, or black stools
    • Severe or worsening abdominal pain

    How To Manage Side Effects

    Dizziness Or Drowsiness

    • Sit or Lie Down: If you feel dizzy, sit down or lie down immediately to prevent falling. Keep your head still and close your eyes if needed.
    • Hydrate: Dehydration can cause dizziness, so drink water or electrolyte-replenishing drinks like sports drinks.
    • Avoid Sudden Movements: When standing or sitting, do so slowly to avoid triggering dizziness. Take your time when getting up.
    • Eat Small, Regular Meals: Low blood sugar can cause dizziness, so eat small meals throughout the day and avoid skipping meals.
    • Fresh Air: Sometimes dizziness can be alleviated by taking slow, deep breaths in a well-ventilated area.

    Headache

    • Rest in a Quiet, Dark Room: Find a calm, quiet space away from bright lights and loud noises. Lie down and close your eyes.
    • Hydrate: Dehydration can contribute to headaches, so drink plenty of water.
    • Apply a Cold or Warm Compress: A cold pack on your forehead may reduce pain, or a warm compress on your neck or shoulders can relieve tension.
    • Over-the-Counter Pain Relief: You can take over-the-counter pain relievers like acetaminophen or ibuprofen if appropriate for you. Follow the recommended dosage.
    • Practice Relaxation Techniques: Deep breathing exercises, meditation, or gentle stretching can help reduce stress and alleviate headache symptoms.

    Warning & Precautions

    Pregnancy

    Contraindicated

    Korandil 5mg Tablet is not recommended for use in pregnant women. It is important to consult your doctor before taking this medication.

    Breastfeeding

    Contraindicated

    Korandil 5mg Tablet is not recommended for use in breast-feeding women. It is important to consult your doctor before taking this medication.

    Driving and Using Machines

    Use with Caution

    Do not drive or operate machines if you experience dizziness or drowsiness.

    Alcohol

    Consult your doctor

    Avoid consumption of alcohol while taking Korandil 5mg Tablet as it can increase dizziness.

    Kidney

    Use with Caution

    Korandil 5mg Tablet should be taken with caution in patients with kidney problems. Consult your doctor before taking it.

    Liver

    Use with Caution

    Korandil 5mg Tablet should be taken with caution in patients with liver disease such as fibrosis of liver and chronic liver disease. Consult your doctor before taking it.

    Allergy

    Contraindicated

    Do not take this medication if you are allergic to Nicorandil or any other ingredients of this medicine.

    Lungs

    Contraindicated

    Korandil 5mg Tablet is not recommended for use in patients having lung disease such as pulmonary oedema (fluid build-up in lungs). Consult your doctor before taking it.

    Heart Disease

    Consult your doctor

    Korandil 5mg Tablet is not recommended for use in patients with heart problems such as cardiogenic shock, left ventricular failure with low filling pressure and cardiac decompensation and should be used with caution in patients with heart failure. Consult your doctor before taking it.

    Use In Pediatrics

    Contraindicated

    Korandil 5mg Tablet is not recommended for use in children and adolescents (aged below 18 years). Consult your pediatrician before giving it.

    Use In Geriatrics

    Use with Caution

    Korandil 5mg Tablet should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking it.

    Other Warnings for KORANDIL 5MG TABLET

    Before taking Korandil 5mg Tablet, inform your doctor if you:

    • low blood pressure
    • signs of low blood potassium levels such as constipation, weakness, muscle damage
    • have glucose-6 phosphate dehydrogenase deficiency (a genetic condition)

    Who should not take [GBNKEYWORD

    Korandil 5mg Tablet is not recommended for use if you:

    • signs of severe low blood pressure such as dizziness, light-headedness or feeling faint
    • signs of low blood volume such as confusion, difficulty breathing or fast breathing, excessive sweating, and loss of consciousness

    Safety Advice

    • Take one tablet once or twice daily with or without food. 
    • Swallow the tablet whole with a glass of water. Do not crush or chew the medication.
    • For best results, take the tablet at the same time each day.
    • Korandil 5mg tablet may cause headaches. If this happens, make sure to stay well-hydrated and take an appropriate painkiller. Contact your doctor if the headache persists.
    • This medication may also cause dizziness or drowsiness. Avoid driving or engaging in activities that require focus until you are aware of how it affects you.
    • Alcohol should be avoided while taking Korandil 5mg tablet, as it can increase dizziness.
    • You should not take medications like sildenafil or tadalafil (used for erectile dysfunction) while on Korandil 5mg tablet, as this may lead to a dangerous drop in blood pressure.
    • If you experience any bleeding from the rectum, blood in your vomit, or black stools, inform your doctor immediately.

    Diet and Lifestyle Advice

    01.How can a healthy lifestyle, including diet, exercise, and lifestyle changes, complement the use of Korandil 5mg (Nicorandil) and improve overall heart health?

    Aspect

    Recommendations

    Benefits

    Diet

    1. Low-Sodium Diet: Limit sodium intake to less than 2,300 mg per day (preferably around 1,500 mg).

    Helps reduce blood pressure, reducing the strain on the heart.

     

    2. High-Fiber Foods: Include whole grains, fruits, vegetables, and legumes in your diet.

    Promotes heart health by lowering cholesterol and improving digestion.

     

    3. Healthy Fats: Consume healthy fats from sources like olive oil, avocados, nuts, and fatty fish (e.g., salmon).

    Reduces bad cholesterol (LDL) and supports good cholesterol (HDL).

     

    4. Limit Processed Foods: Avoid foods high in trans fats, added sugars, and refined carbohydrates.

    Reduces the risk of heart disease, maintains healthy weight.

     

    5. Potassium-Rich Foods: Include bananas, spinach, potatoes, and tomatoes in your meals.

    Helps balance sodium levels, reduces the risk of high blood pressure.

    Exercise

    1. Regular Cardiovascular Exercise: Aim for at least 150 minutes of moderate-intensity aerobic exercise weekly (e.g., walking, swimming, cycling).

    Improves heart function, lowers blood pressure, and strengthens the cardiovascular system.

     

    2. Strength Training: Perform strength training exercises (e.g., resistance bands, weight lifting) 2-3 times a week.

    Increases muscle strength, helps maintain a healthy weight.

     

    3. Stretching and Yoga: Practice stretching or yoga for flexibility and stress relief.

    Enhances circulation, improves flexibility, and reduces stress.

     

    4. Consistent Physical Activity: Aim to be active throughout the day (e.g., walking, taking stairs, gardening).

    Boosts overall fitness and supports a healthy weight.

    Lifestyle Changes

    1. Stress Management: Practice relaxation techniques like meditation, deep breathing, or mindfulness.

    Reduces stress and anxiety, lowering the risk of heart disease.

     

    2. Quit Smoking: If you smoke, seek help to quit.

    Improves circulation, lowers the risk of heart attack, and reduces plaque buildup in arteries.

     

    3. Limit Alcohol: Drink alcohol in moderation—up to one drink per day for women and two for men.

    Helps prevent high blood pressure, arrhythmias, and liver damage.

     

    4. Adequate Sleep: Aim for 7-9 hours of quality sleep per night.

    Essential for heart health, reducing stress and improving overall wellbeing.

     

    5. Regular Health Monitoring: Check blood pressure, cholesterol, and blood sugar levels regularly.

    Enables early detection and management of potential heart health issues.

     

    02. What are the practical diet recommendations for managing heart health while taking Korandil 5mg, including foods to eat and avoid?

    Food Group

    Recommended Foods

    Foods to Avoid

    Benefits

    Fruits & Vegetables

    - Berries (blueberries, strawberries)
    - Leafy greens (spinach, kale)
    - Apples, oranges, and bananas

    - Canned fruits with added sugar
    - Fried vegetables with added fats

    Rich in antioxidants, fiber, and potassium to support heart health.

    Whole Grains

    - Oats, quinoa, brown rice, barley
    - Whole wheat bread, whole grain pasta

    - Refined grains (white bread, white rice, pastries)

    Helps lower cholesterol, improves digestion, and maintains healthy weight.

    Healthy Fats

    - Olive oil, avocado, nuts (walnuts, almonds)
    - Fatty fish (salmon, mackerel, sardines)

    - Trans fats (found in processed foods, fried items)
    - Saturated fats (butter, lard)

    Reduces LDL cholesterol and supports cardiovascular function.

    Lean Proteins

    - Skinless poultry
    - Legumes (lentils, beans)
    - Tofu, low-fat dairy products

    - Processed meats (sausage, hot dogs)
    - Red meat (beef, lamb)

    Provides necessary protein while limiting unhealthy fats.

    Low-Fat Dairy

    - Low-fat or fat-free milk, yogurt, and cheese

    - Full-fat dairy products (cheese, cream)

    Helps lower saturated fat intake, contributing to lower cholesterol.

    Legumes & Beans

    - Lentils, chickpeas, kidney beans, black beans

    - High-fat baked beans (in syrup or with unhealthy additives)

    Rich in fiber and plant-based proteins that help control cholesterol levels.

    Nuts & Seeds

    - Walnuts, almonds, chia seeds, flaxseeds

    - Salted nuts, roasted nuts with added fats or sugars

    Provide heart-healthy fats and fiber to reduce inflammation.

    Beverages

    - Water, herbal teas (green tea, chamomile)
    - Freshly squeezed fruit juices (without added sugar)

    - Sugary soft drinks, caffeinated beverages, alcohol in excess

    Keeps you hydrated and prevents sugar spikes that affect heart health.

    Salt & Sodium

    - Use herbs and spices for flavoring (garlic, turmeric, cinnamon)
    - Salt alternatives (potassium chloride)

    - High-sodium processed foods (canned soups, salty snacks, fast food)

    Helps control blood pressure and reduce fluid retention.

    Sweets & Snacks

    - Fresh fruit, dark chocolate (70% cocoa or higher)
    - Homemade baked goods with whole grain flour

    - Sugary candies, cakes, pastries, and sugary snacks

    Keeps blood sugar stable and prevents excessive weight gain.

    Drug - Drug interaction

    Inform your physician if you are taking any of the following medicine before taking Korandil 5mg Tablet:

    1. Other Antihypertensive Medications

    • Interactions: Combining Korandil with other blood pressure-lowering medications, such as ACE inhibitors (e.g., enalapril), calcium channel blockers (e.g., amlodipine), or diuretics (e.g., furosemide), can lead to an enhanced hypotensive effect.
    • Effects: Severe hypotension, dizziness, fainting, and risk of renal impairment.
    • Management: Monitor blood pressure regularly. Dose adjustments of either Korandil or the antihypertensive medications may be required. Start at lower doses and titrate gradually to avoid excessive lowering of blood pressure.

    2. Potassium-Reducing Medications (e.g., Diuretics)

    • Interactions: Nicorandil may increase the potassium levels in the blood when used alongside potassium-sparing diuretics (e.g., spironolactone).
    • Effects: Hyperkalemia, which can cause muscle weakness, arrhythmias, or cardiac arrest.
    • Management: Regular monitoring of potassium levels is crucial, especially during the early stages of treatment. If hyperkalemia develops, consider adjusting the dosage or switching to a different medication.

    3. Nitrates and Nitric Oxide Donors

    • Interactions: Since Nicorandil has nitrate-like effects, combining it with other nitrates or nitric oxide donors (e.g., nitroglycerin) may cause profound vasodilation.
    • Effects: Extreme hypotension, syncope, and reflex tachycardia.
    • Management: Avoid concurrent use of other nitrates or nitric oxide donors. If needed, monitor blood pressure closely and adjust dosages of both medications. Ensure gradual titration.

    4. Phosphodiesterase Type 5 Inhibitors (e.g., Sildenafil)

    • Interactions: Combining Korandil with phosphodiesterase type 5 inhibitors (PDE5 inhibitors), which are commonly used for erectile dysfunction, may potentiate the vasodilatory effects of both drugs.
    • Effects: Severe hypotension, dizziness, fainting, and tachycardia.
    • Management: These combinations should be avoided due to the risk of life-threatening hypotension. If use is absolutely necessary, it should be under strict medical supervision with frequent monitoring of blood pressure.

    5. Antiarrhythmic Medications (e.g., Amiodarone, Beta-Blockers)

    • Interactions: Nicorandil may enhance the effects of antiarrhythmic medications, especially beta-blockers and amiodarone.
    • Effects: Excessive bradycardia, heart block, or hypotension.
    • Management: Monitor heart rate and blood pressure closely. Adjust doses of both Nicorandil and antiarrhythmic medications as needed to avoid excessive cardiovascular effects.

    6. Alcohol

    • Interactions: Alcohol can enhance the vasodilatory effects of Nicorandil, potentially increasing the risk of hypotension.
    • Effects: Increased risk of dizziness, fainting, and severe hypotension.
    • Management: Advise patients to limit alcohol consumption while on Nicorandil. Monitor for symptoms of hypotension and adjust the treatment if necessary.

    7. Other Medications Affecting Renal Function (e.g., NSAIDs, ACE Inhibitors)

    • Interactions: Nicorandil can be affected by renal function, and when used with medications that impact kidney function (like NSAIDs or ACE inhibitors), there may be an increased risk of renal impairment.
    • Effects: Acute renal failure, fluid retention, and electrolyte imbalances.
    • Management: Regular monitoring of renal function (serum creatinine, eGFR) is advised. If renal impairment develops, dose adjustments or discontinuation of one or both medications may be required.

    Synopsis

    Drug :   Nicorandil
    Pharmacological Category :   Potassium channel activators
    Therapeutic Indication :   Angina pectoris
    Dosage Forms :   Tablet, Injection

    More Information

    Storage

    • Store Korandil 5mg Tablet at room temperature, typically between 20-25°C
    • Keep this medication away from direct sunlight, heat sources, and humidity to maintain its effectiveness
    • Store the medications in a safe location, out of reach of children and pets
    • Never freeze Korandil 5mg Tablet, as freezing can damage the medication

    FAQs About KORANDIL 5MG TABLET

    Q: What is Korandil 5mg Tablet used for?

    A: Korandil 5mg Tablet contains Nicorandil and is primarily used to manage angina (chest pain) caused by coronary artery disease. It helps to improve blood flow to the heart.

    Q: How does Korandil 5mg Tablet work?

    A: Korandil 5mg Tablet works by relaxing the blood vessels, improving blood flow to the heart, and reducing the strain on the heart muscle. It acts as both a nitrate and a potassium channel opener, helping to prevent chest pain and increase oxygen supply to the heart.

    Q: What is the recommended dosage of Korandil 5mg Tablet?

    A: The typical dosage of Korandil 5mg Tablet is one tablet taken twice daily, or as prescribed by your doctor. Always follow the prescribed dosage instructions and do not exceed the recommended dose.

    Q: What are the possible side effects of Korandil 5mg Tablet?

    A: Common side effects of Korandil 5mg Tablet may include dizziness, headache, flushing, and a feeling of warmth. In some cases, more serious side effects like low blood pressure or palpitations may occur. Always consult your doctor if you experience any adverse effects.

    Q: Can Korandil 5mg Tablet be used during pregnancy?

    A: Korandil 5mg Tablet is not recommended for use in pregnant women. It is important to consult your doctor before taking this medication.

    Q: Are there any drug interactions with Korandil 5mg Tablet?

    A: Yes, Korandil 5mg Tablet may interact with other medications such as blood pressure medications, nitrates, or other heart-related drugs. Always inform your doctor of any other medications or supplements you are taking to avoid potential interactions.

    Q: Can Korandil 5mg Tablet be taken with food or alcohol?

    A: Korandil 5mg Tablet can be taken with or without food. However, alcohol can increase the risk of certain side effects, such as dizziness or low blood pressure, so it is advisable to limit alcohol consumption while taking this medication.

    Q: What should I do if I miss a dose of Korandil 5mg Tablet?

    A: If you miss a dose of Korandil 5mg Tablet, take it as soon as you remember, unless it is almost time for your next dose. Do not double the dose to make up for a missed one. Always consult your doctor.

    Q: Can Korandil 5mg Tablet be used to manage other heart conditions?

    A: Korandil 5mg Tablet is mainly used for angina (chest pain) related to coronary artery disease. For other heart conditions, consult your doctor for appropriate management options.

    Q: How should Korandil 5mg Tablet be stored?

    A: Store Korandil 5mg Tablet in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and ensure the medication is securely closed when not in use.

    Q: What should I do if I overdose on Korandil 5mg?

    A: If you overdose on Korandil 5mg, seek immediate medical attention. Symptoms of an overdose may include extreme dizziness, fainting, or a significant drop in blood pressure. It is important to contact your doctor or a poison control center for guidance on how to manage the overdose.

    Q: Is Korandil 5mg effective for long-term use in heart disease?

    A: Yes, Korandil 5mg can be used effectively for long-term management of heart disease, particularly for reducing angina (chest pain) caused by coronary artery disease. It helps by improving blood flow to the heart, reducing the frequency of angina attacks, and enhancing the overall quality of life. Always follow your doctor's recommendations for long-term use.

    Q: Can Korandil 5mg be used to manage chest pain during a heart attack?

    A: Korandil 5mg is not typically used during a heart attack for immediate management. While it can help reduce angina in stable conditions, during an active heart attack, other medications like thrombolytics or antiplatelets are usually preferred. Always seek emergency medical care if you suspect a heart attack.

    Q: Does Korandil 5mg work faster than other angina medications?

    A: Korandil 5mg can be effective in relieving angina, but its action may not be as rapid as some other medications like nitroglycerin, which is often used for quick relief during acute chest pain. Korandil is more suitable for long-term management of angina, and its effect is typically seen over time. Always consult your doctor for the best medication for your specific condition.

    Q: Where can I buy Korandil 5mg tablet online?

    A: You can buy Korandil 5mg tablet online at Netmeds. Just visit their website and search for the product, and you will find options to purchase it directly from there.

    References

    1. KD. Tripathi. Antianginal and other Anti-ischemic Drugs. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 552.

    2. Kevin Cheng, Khaldoon Alhumood, Fayez El Shaer, and Ranil De Silva. The Role of Nicorandil in the Management of Chronic Coronary Syndromes in the Gulf Region. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. December 2020. [Accessed on 2nd April 2025] 

    3. Jason M. Tarkin and Juan Carlos Kaski. Vasodilator Therapy: Nitrates and Nicorandil. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. June 2016. [Accessed on 2nd April 2025] 

    4. Dexcel Pharma Ltd. Electronic Medicines Compendium (EMC). [Revised in January 2022] [Accessed on 2nd April 2025] 

    5. West-Coast Pharmaceutical Works Ltd. Nicovex-5 (Nicorandil Tablets BP 5 mg). [Accessed on 2nd April 2025] 

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    Author Details

    Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)
    Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)
    Last updated on 02 Apr 2025 | 02:47 PM(IST)
    Lab updated