DEPLATT CV 20 Capsule 15's

Introduction About DEPLATT CV 20 CAPSULE

What is DEPLATT CV 20 CAPSULE?

DEPLATT CV 20 CAPSULE is a combination medication used for heart disease management, reducing blood clots, and improving blood circulation.

DEPLATT CV 20 CAPSULE is used to manage heart attacks and strokes, reduces blood clot formation and improves heart health.

Take DEPLATT CV 20 CAPSULE as prescribed by your doctor. It is usually taken once daily with water, preferably after a meal.

Avoid drinking alcohol while taking DEPLATT CV 20 CAPSULE, as it could increase the risk of bleeding in the gastrointestinal tract.

The most common side effects include nausea, stomach pain, dizziness, and increased bleeding risk. Consult your doctor if you experience any of the above side effects.

Key Composition

• Aspirin (75mg): Antiplatelet Agent - Aspirin inhibits the cyclooxygenase (COX-1 and COX-2) enzymes, reducing thromboxane A2 production, which prevents platelets from sticking together and forming clots
• Atorvastatin (20mg): Statin (Cholesterol-Lowering agent) - Atorvastatin inhibits HMG-CoA reductase, an enzyme involved in cholesterol synthesis in the liver, thereby reducing cholesterol levels and preventing arterial blockages
• Clopidogrel (75mg): Antiplatelet Agent - Clopidogrel blocks the P2Y12 receptor on platelets, preventing platelet activation and clot formation.

Uses Of DEPLATT CV 20 CAPSULE

Used to:

• manage heart disease
• reduce blood clots
• improve blood circulation

Benefits of DEPLATT CV 20 CAPSULE

1. Manages Heart attacks and Strokes:

• Manages recurrence of heart attacks and strokes in high-risk individuals
• Reduces arterial blockages by controlling cholesterol levels and manages plaque buildup
• Enhances blood circulation, ensuring oxygen-rich blood reaches the heart and brain

2. Reduces Blood clot formation:

• Aspirin & Clopidogrel work as antiplatelet agents, managing platelets from sticking together and forming dangerous clots
• Lowers the risk of thrombosis, which can lead to life-threatening conditions like heart attacks and strokes
• Ensures smooth blood flow, reducing the chances of clot-related complications

3. Improves heart health:

• Atorvastatin lowers LDL cholesterol, reducing fatty deposits in arteries
• Increases HDL cholesterol, promoting better cardiovascular function
• Reduces inflammation in blood vessels, decreasing the risk of atherosclerosis

How DEPLATT CV 20 CAPSULE Works

How DEPLATT CV 20 CAPSULE helps to manage Heart attack and Stroke:

1. Manage blood clots (Aspirin + Clopidogrel – Antiplatelet action)

• Heart attacks and strokes occur due to blocked arteries, often caused by blood clots
• Aspirin blocks thromboxane A2 production, managing platelets from clumping together
• Clopidogrel inhibits P2Y12 receptors, further reducing platelet aggregation
• Together, they ensure smoother blood flow and reduce the risk of clot formation in arteries supplying the heart and brain

2. Lowers cholesterol & manages arterial blockage (Atorvastatin – Statin Action):

• Atorvastatin inhibits HMG-CoA reductase, reducing cholesterol production in the liver
• Lowers LDL cholesterol levels, manages atherosclerosis (artery hardening)
• Increases HDL (good cholesterol), helping to remove excess fat deposits

3. Reduces inflammation & improves blood vessel health:

• Aspirin & Atorvastatin reduce inflammation in arteries, decreasing oxidative stress
• Manages the rupture of plaques, a major cause of sudden heart attacks
• Maintains healthy, flexible arteries, ensuring steady blood flow to the heart and brain

How to use DEPLATT CV 20 CAPSULE

Dosage guidelines for different age groups:

• Recommended dosage: one capsule per day, usually taken at night
• Swallow whole with water, preferably after food to reduce stomach irritation
• Long-term use as prescribed by a doctor for heart attack and stroke prevention
• Dosages will be adjusted accordingly for special cases like patients with liver, kidney disease and patients taking blood thinners

How to take DEPLATT CV 20 CAPSULE for maximum effectiveness:

• Always follow correct dosage & timing
• How to administer the medicine
• Keep in mind and ask your physician what to avoid while taking DEPLATT CV 20 CAPSULE
• Follow lifestyle tips to enhance effectiveness

How long should I take DEPLATT CV 20 CAPSULE ?

• Short-term (few months to a year): For patients recovering from a recent heart attack, stroke, or surgery
• Long-Term (lifelong therapy): For individuals with chronic heart disease, high cholesterol, or a high risk of clot formation
• Do not stop taking DEPLATT CV 20 CAPSULE suddenly without consulting your doctor

What if I forgot to take DEPLATT CV 20 CAPSULE

• If you realize soon after missing a dose, take it immediately with water
• If it is almost time for your next dose, skip the missed dose and continue your regular schedule
• Never take two capsules at once to make up for a missed dose

Overdose

• Mild to moderate overdose symptoms: Nausea, vomiting, or stomach pain, dizziness or headaches, ringing in the ears, weakness
• Severe overdose symptoms: Uncontrolled bleeding, severe dizziness or fainting, rapid or irregular heartbeat, difficulty breathing, seizures or unconsciousness
• Call your doctor or go to the nearest emergency room immediately

Side Effects Of DEPLATT CV 20 CAPSULE

Common side effects:

• nausea
• stomach pain
• dizziness
• increased bleeding risk

When to consult a doctor?

• severe allergic reactions
• thrombotic thrombocytopenic purpura
• hemorrhagic vasculitis
• abnormal heavy or prolonged menstrual periods
• severe skin disorders with fever
• rhabdomyolysis, myositis or tendinopathy

How To Manage Side Effects

Dizziness Or Drowsiness

• Get up slowly to avoid sudden drops in blood pressure
• Drink plenty of water to prevent dehydration, which can worsen dizziness
• Avoid strenuous activities or lifting heavy objects if you feel lightheaded

Nausea And Vomiting

• Always take DEPLATT CV 20 CAPSULE after a meal to reduce stomach irritation
• Drink plenty of water throughout the day
• Opt for light, bland foods like crackers, toast, or bananas

Stomach Pain

• Drink a glass of milk or have a light snack when taking it
• Wait at least 30–60 minutes before lying down to manage acid reflux
• Ginger or chamomile tea can help soothe stomach discomfort

Warning & Precautions

Pregnancy

Contraindicated

DEPLATT CV 20 CAPSULE is not recommended during pregnancy unless absolutely necessary. Aspirin in low dose sometimes prescribed in pregnancy to manage pre-eclampsia and clot-related complications. However, high doses (like in DEPLATT CV 20 CAPSULE) may cause fetal complications (bleeding risks, delayed labor). Atorvastatin classified as Pregnancy Category X by the FDA, meaning it is strictly contraindicated due to risks of birth defects. Clopidogrel have limited human studies, however, its use during pregnancy is only advised when the benefits outweigh the risks.   

Breastfeeding

Contraindicated

DEPLATT CV 20 CAPSULE is generally avoided while breastfeeding due to potential risks for the baby. Aspirin may pass into breast milk in small amounts, possibly causing bleeding issues in the infant. Atorvastatin has no sufficient human studies, however, statins may interfere with infant development, so they are not recommended during breastfeeding. Clopidogrel have limited data on its presence in breast milk and safety is unclear.

Driving and Using Machines

Use with Caution

DEPLATT CV 20 CAPSULE does not impair your ability to drive or operate any machines.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking DEPLATT CV 20 CAPSULE as it may increase the risk of stomach bleeding and aggravate your existing condition.

Kidney

Contraindicated

Do not take DEPLATT CV 20 CAPSULE if you have severe kidney disease requiring dialysis or acute kidney injury (AKI). Avoid long-term use in advanced kidney disease (e.g., Stage 4-5 CKD or dialysis patients). Kidney function (creatinine, GFR) should be monitored regularly. Dosage adjustments may be required based on kidney function.

Liver

Contraindicated

DEPLATT CV 20 CAPSULE is not recommended if you have severe liver impairment or active liver disease or have a history of alcohol-induced liver damage. Liver function tests (LFTs) should be monitored before and during treatment. Doctors may adjust the dose or switch to safer alternatives.

 

Allergy

Contraindicated

Do not take DEPLATT CV 20 CAPSULE if you are allergic to Clopidogrel, Atorvastatin, Aspirin or any other ingredients of this medicine.

Lungs

Use with Caution

DEPLATT CV 20 CAPSULE should be used with caution in patients with interstitial lung disease or other respiratory problems such as hay fever, asthma or chronic respiratory diseases due to increased risk of bronchospasm and asthma attacks.

Heart Disease

Consult your doctor

DEPLATT CV 20 CAPSULE is not recommended for use in patients with recent ischemic stroke and should be used with caution in patients with high blood pressure.

Use In Pediatrics

Contraindicated

DEPLATT CV 20 CAPSULE is generally not recommended for use in children and adolescents (under 18 years of age).

Use In Geriatrics

Use with Caution

DEPLATT CV 20 CAPSULE should be used with caution in elderly patients (aged 70 years or above) because of increased risk of gastro-intestinal bleeding and perforation when used for prolonged duration (if prolonged therapy is essential, patients should be reviewed regularly).

Other Warnings for DEPLATT CV 20 CAPSULE

Before taking DEPLATT CV 20 CAPSULE inform your doctor if you:

• have an underactive thyroid gland
• have family history of hereditary muscular disorders
• have family history of muscle problems following management with cholesterol-lowering medicines
• have upcoming planned surgery
• have dehydration problem
• have diabetes

Who should not take [GBNKEYWORD

DEPLATT CV 20 CAPSULE is not recommended for use if you:

• have active or recurrent peptic ulcer with or without gastrointestinal bleeding
• have bleeding disorders
• have thrombocytopenia
• have gout
• have menorrhagia

Diet and Lifestyle Advice

Daily heart health tips for patients on DEPLATT CV 20 CAPSULE :

• Always take DEPLATT CV 20 CAPSULE at the same time each day to maintain effectiveness
• Follow a heart-healthy diet
• Stay active with daily exercise
• Monitor your blood pressure & cholesterol
• Manage stress for a healthy heart
• Stay hydrated & get enough sleep

Foods to eat & avoid while taking DEPLATT CV 20 CAPSULE :

Foods to eat (heart-healthy choices)

1. Omega-3 Rich Foods: avocados, fatty fish (salmon, mackerel, sardines), walnuts & flaxseeds

2. High-fiber foods: whole grains (oats, brown rice, whole wheat bread), fruits (apples, berries, bananas), vegetables (spinach, kale, carrots) and legumes (lentils, beans, chickpeas)

3. Anti-Inflammatory & antioxidant foods: tomatoes, green tea and nuts

4. Low-sodium & potassium-rich foods: sweet potatoes, bananas and avocados

Foods to avoid (harmful to heart & medication effectiveness)

1. High-sodium & processed foods: Canned soups & processed meats, packaged snacks (chips, instant noodles), fast food (fried chicken, burgers, pizza)

2. High-sugar foods: soft drinks, packaged fruit juices, candies, cookies, cakes, white bread & refined pasta

3. High-fat & cholesterol-rich foods: red meat, full-fat dairy and fried foods (french fries, fried chicken)

Best exercises for heart health while taking this medication:

• Brisk walking: 30–45 minutes daily
• Cycling: 20–30 minutes
• Swimming: 20–30 minutes
• Deep breathing: 15–30 minutes daily
• Strength training: 2–3 times a week
• Stretching & balance exercises: 5–10 minutes

Drug - Drug interaction

Medications to avoid while taking DEPLATT CV 20 CAPSULE?:

1. Blood thinners & Antiplatelet drugs (increased bleeding risk):

• Warfarin, Heparin, Apixaban, Rivaroxaban, Dabigatran, NSAIDs (Ibuprofen, Naproxen, Diclofenac)
• Alternative: If pain relief is needed, ask your doctor about using Paracetamol (Acetaminophen) instead

2. Cholesterol-lowering drugs (risk of muscle & liver damage):

• Atorvastatin, other statins (simvastatin, rosuvastatin, pravastatin), fibrates (fenofibrate, gemfibrozil)
• Alternative: Diet & lifestyle changes may help reduce cholesterol without additional medication

3. Certain antibiotics & antifungals (risk of liver damage):

• Clarithromycin, erythromycin, ketoconazole, itraconazole
• Alternative: Your doctor may adjust the statin dose or switch antibiotics if needed

4. Diabetes medications (blood sugar fluctuations):

• Insulin & sulfonylureas (glimepiride, glyburide)
• Solution: Monitor blood sugar levels frequently and adjust diabetes medications as per your doctor's advice

5. Acid Reducers & antacids (reduce medication effectiveness):

• Omeprazole, esomeprazole

Synopsis

More Information

Is DEPLATT CV 20 CAPSULE safe for long-term use?

Benefits of long-term use:

• Manages heart attacks & strokes – Helps to manage blood clot formation
• Lowers cholesterol – Atorvastatin reduces LDL cholesterol and improves heart health
• Improves blood circulation – Aspirin & Clopidogrel act as blood thinners, reducing clot risk
• Supports post-surgery recovery – Often prescribed after angioplasty or bypass surgery

How is DEPLATT CV 20 CAPSULE different from regular aspirin?

DEPLATT CV 20 CAPSULE vs Ecosprin 75mg: which one to take?

Other medications that work like DEPLATT CV 20 CAPSULE :

1. Clopivas Gold 20mg

• Composition: Aspirin (75mg) + Clopidogrel (75mg) + Atorvastatin (20mg)
• Works similarly: Manages blood clot formation and reduces cholesterol
• Why choose it? Alternative brand with the same active ingredients

2. Deplatt CV 20mg

• Composition: Aspirin (75mg) + Clopidogrel (75mg) + Atorvastatin (20mg)
• Works similarly: Manages heart attacks and strokes in high-risk patients
• Why choose it? Doctor may switch due to availability or pricing

3. Clopitab A 150/75

• Composition: Aspirin (150mg/75mg) + Clopidogrel (75mg)
• Works similarly: Blood thinning to reduce stroke & heart attacks
• Difference from DEPLATT CV 20 CAPSULE ? Lacks Atorvastatin, so it does not control cholesterol

Who should avoid taking DEPLATT CV 20 CAPSULE ?

• People with active bleeding disorders
• People with severe liver or kidney disease
• People allergic to aspirin, clopidogrel, or atorvastatin
• Pregnant or breastfeeding women
• People with a history of stroke caused by bleeding (hemorrhagic stroke)
• People scheduled for surgery or dental procedures
• People with uncontrolled high blood pressure (hypertension)

FAQs About DEPLATT CV 20 CAPSULE

Q: What is DEPLATT CV 20 CAPSULE used for?

A: DEPLATT CV 20 CAPSULE is used for heart disease management, reducing blood clots, and improving blood circulation. It is also used to manage heart attacks and strokes, reduces blood clot formation and improves heart health.

Q: How should I take DEPLATT CV 20 CAPSULE?

A: Take DEPLATT CV 20 CAPSULE as directed by your doctor. It is typically taken once daily with food to reduce stomach irritation. Swallow the capsule whole with water and take it at the same time each day for the best results. Do not skip doses or stop taking the medicine without consulting your doctor.

Q: What are the common side effects of DEPLATT CV 20 CAPSULE?

A: The most common side effects include nausea, stomach pain, dizziness, and increased bleeding risk. Consult your doctor if you experience any of the above side effects.

Q: Can I take DEPLATT CV 20 CAPSULE during pregnancy?

A: No, DEPLATT CV 20 CAPSULE is generally not recommended during pregnancy unless prescribed by a doctor.

Q: What should I do if I miss a dose of DEPLATT CV 20 CAPSULE?

A: If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Q: Can I consume alcohol while taking DEPLATT CV 20 CAPSULE?

A: It is advisable to avoid alcohol while taking DEPLATT CV 20 CAPSULE, as it can increase the risk of side effects like stomach irritation and bleeding. Additionally, alcohol can interfere with cholesterol management and reduce the effectiveness of the medication.

Q: What precautions should I take while using DEPLATT CV 20 CAPSULE?

A: Use caution while performing activities that may cause injuries, as this medicine increases the risk of bleeding. Avoid over-the-counter NSAIDs like ibuprofen unless prescribed. Inform your doctor about any other medications you are taking to manage interactions. Regularly monitor your cholesterol levels and report any unusual symptoms to your doctor.

Q: How long do I need to take DEPLATT CV 20 CAPSULE?

A: DEPLATT CV 20 CAPSULE is often prescribed as part of a long-term treatment plan for cardiovascular health. Your doctor will determine the duration based on your condition. Do not stop taking the medication without medical advice, even if you feel better.

Q: Are there any dietary restrictions while taking DEPLATT CV 20 CAPSULE?

A: Yes, follow a heart-healthy diet for the best results. Avoid foods high in saturated fats, trans fats, and cholesterol. Incorporate fresh fruits, vegetables, whole grains, and lean proteins. Reduce sodium intake and quit smoking to improve overall heart health.

Q: Can DEPLATT CV 20 CAPSULE interact with other medications?

A: Yes. DEPLATT CV 20 CAPSULE may interact with blood thinners, NSAIDs, and certain antibiotics, increasing the risk of side effects. Inform your doctor about all medications, supplements, or herbal products you are taking to avoid adverse interactions.

Q: Can I take DEPLATT CV 20 CAPSULE daily?

A: Yes, but only under medical supervision.

Q: Is DEPLATT CV 20 CAPSULE safe for long-term use?

A: Long-term use of DEPLATT CV 20 CAPSULE should be monitored by a doctor to avoid complications.

References

1. KD. Tripathi. Drugs Affecting Coagulation, Bleeding and Thrombosis and Hypolipidemic Drugs and Plasma Expanders. Essentials of medical pharmacology. Seventh edition. 2013. Page – 629-633 & 636-638.
2. Jeffery I. Weitz. Blood coagulation and Anticoagulant, Fibrinolytic and Antiplatelet Drugs. Thomas P. Bersot. Drug therapy for hypercholesterolemia and dyslipidemia. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 868-870 & 892-898.
3. Goeng Bae Kim, Jeong Kyung Kim, Sul Park, Jae Jin Jeong, Hyung Sik Yoon, Sang Hun Ko, Jae Ee Ko, Soo Jin Park, Seon Woo Nam, Jae Hwan Lee and Min Soo Hyon. Effect of Atorvastatin and Clopidogrel Co-Administration After Coronary Stenting in Korean Patients With Stable Angina. NCBI; PMC US National Library of Medicine, National Institute of Health. January 2011. [Accessed on 2nd April 2025] 
4. Torrent pharmaceuticals ltd. Deplatt-CV. Torrentian.com. [Revised in July 2019]. [Accessed on 2nd April 2025] 
5. Torrent pharmaceuticals ltd. Deplatt-CV 20 Forte (Clopidogrel, Atorvastatin and Aspirin Capsules). Torrentian.com. [Revised in July 2019] [Accessed on 2nd April 2025] 

Useful Diagnostic Tests

• Cardiac Risk Profile
• Lipid Profile

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 22 May 2025 | 05:20 PM(IST)