Cardace Meto 2.5 Tablet 10'S

Introduction About CARDACE METO 2.5/25MG TABLET

Cardace Meto 2.5 Tablet is a combination medicine designed to support patients with cardiovascular concerns. It is particularly useful for individuals who need dual action on blood pressure and heart rate, such as patients with hypertension accompanied by elevated heart rate, angina (chest pain), or early-stage heart failure. By addressing both vascular tension and heart workload, it helps patients maintain better cardiovascular stability and improves quality of life.

Cardace Meto 2.5 Tablet combines ramipril (ACE inhibitor) and metoprolol (beta-blocker). Ramipril relaxes blood vessels, lowers vascular resistance, and reduces fluid retention, while metoprolol slows the heart rate and reduces cardiac oxygen demand. It is ideal for patients with hypertension, angina, or those requiring kidney protection, particularly in individuals with diabetes or early signs of heart strain. Elderly patients and those with risk factors for cardiovascular complications can also benefit under medical supervision.

The tablet is usually taken once daily, preferably at the same time each day, and can be taken with or without food. It should be swallowed whole with a glass of water. Patients are advised not to stop or change the dose on their own, and missed doses should only be taken if there is sufficient time before the next scheduled dose. Regular monitoring of blood pressure, heart rate, and kidney function is recommended to ensure safety and effectiveness.

Cardace Meto 2.5 Tablet should be used under medical supervision, especially in patients with kidney or liver problems. Common side effects include dizziness, fatigue, headache, mild nausea, or slow heart rate. Patients should avoid alcohol and be cautious with medicines that may lower blood pressure or slow the heart. The medicine is not generally recommended during pregnancy or breastfeeding unless prescribed by a doctor. Regular follow-up appointments help detect any adverse effects early and ensure optimal therapy. 

Uses Of CARDACE METO 2.5/25MG TABLET

• Used to manage hypertension and angina
• Used to manage heart failure
• Used to protect kidney functions in patients with hypertension and diabetes

Benefits of CARDACE METO 2.5/25MG TABLET

Cardace Meto 2.5 Tablet for Hypertension

Cardace Meto 2.5 Tablet helps manage high blood pressure by combining ramipril (ACE inhibitor) and metoprolol (beta-blocker). Ramipril relaxes and widens blood vessels, while metoprolol slows the heart rate and reduces workload. Together, they support stable blood pressure levels, improve circulation, and reduce strain on the heart. Regular monitoring of blood pressure and adherence to a healthy lifestyle enhances its effectiveness.

Cardace Meto 2.5 Tablet for Angina

For patients with angina (chest pain caused by reduced blood flow to the heart), Cardace Meto 2.5 Tablet helps by reducing heart workload and improving oxygen supply. Metoprolol slows the heart rate and decreases oxygen demand, while ramipril relaxes blood vessels. This combination can help reduce the frequency and severity of angina episodes under medical supervision.

Cardace Meto 2.5 Tablet for Heart Failure

In heart failure, Cardace Meto 2.5 Tablet supports the heart by lowering blood pressure, reducing heart rate, and easing the heart’s workload. Ramipril helps relax blood vessels, improving blood flow, while metoprolol reduces the stress on the heart by slowing contractions. This dual action can improve symptoms, support heart function, and reduce the risk of complications in patients with chronic heart conditions.

How CARDACE METO 2.5/25MG TABLET Works

Mechanism of action of Cardace Meto 2.5 Tablet

Cardace Meto 2.5 Tablet combines ramipril and metoprolol to support effective blood pressure and heart rate control through two complementary actions.

Ramipril, an ACE inhibitor, helps relax and widen blood vessels by reducing angiotensin II formation, improving blood flow and lowering vascular resistance. It also reduces fluid retention, easing the heart’s workload. Metoprolol, a selective beta-1 blocker, slows the heart rate and decreases the force of contraction by limiting the effects of stress hormones like adrenaline, helping stabilize heart function.

Together, this dual action supports cardiovascular stability and balanced blood pressure regulation under medical guidance.

How to use CARDACE METO 2.5/25MG TABLET

How to Take Cardace Meto 2.5 Tablet

• Take Cardace Meto 2.5 Tablet exactly as prescribed by your doctor.
• Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
• It is usually taken once daily, preferably at the same time each day to maintain consistency.
• The tablet may be taken with or without food, but taking it the same way each day helps avoid stomach discomfort.
• Do not stop or change the dose on your own, even if you feel well, unless advised by your doctor.
• If you miss a dose, take it as soon as you remember; skip it if it is almost time for the next dose. Do not double the dose.
• Regular follow-up and monitoring as advised by your healthcare provider help ensure safe and effective use.

What if I forgot to take CARDACE METO 2.5/25MG TABLET

• If you miss a dose, take it as soon as you remember.
• If it’s almost time for your next scheduled dose, skip the missed dose do not take a double dose to make up for it.
• Taking a double dose can lower your blood pressure too much or slow your heart rate, which can be dangerous.
• Try to take the tablet at the same time every day to maintain consistent blood levels and better control of blood pressure and heart rate.
• If you frequently forget doses, consider setting a daily alarm or reminder and keep a log of when you take your medicine

Overdose

If you or anyone else accidentally took more Cardace Meto 2.5/25mg Tablet, consult your doctor immediately. Symptoms of overdose might include low blood pressure, tiredness, dizziness, slow pulse, shortness of breath, nausea, vomiting, blue colouring of the skin, low blood sugar levels and high levels of potassium in the blood.

Side Effects Of CARDACE METO 2.5/25MG TABLET

Common side effects of Cardace 2.5mg Tablet

• headache, tiredness, dizziness
• feeling faint or dizzy while standing up
• dry cough, inflammation of sinus
• stomach pain, nausea, vomiting, diarrhoea, indigestion
• skin rash
• chest pain
• muscle pains
• increased potassium levels in blood
• slow heart rate

When to Seek Medical Attention?

Stop taking Cardace Meto 2.5/25mg Tablet and contact your doctor immediately if you experience any of the following side effects:

• signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth or throat which can lead to difficulty in breathing or swallowing)
• severe skin reactions (such as skin rash with itching and redness, blistering and peeling of skin, skin swelling and inflammation of mucous membrane)
• chest pain, shortness of breath (signs of heart attack)
• inflammation of pancreas (causing severe stomach pain that radiates to the back side of the body)
• signs of liver problems (such as fever, muscle pain, rashes, itching, stomach pain, diarrhoea, discoloration of eyes, skin and urine)
• increased bleeding or bruising, fever, chills, red spots under the skin, tiredness, dizziness, pale skin (signs of low blood cells counts)

How To Manage Side Effects

Diarrhea

• Stay hydrated: Drink plenty of water, oral rehydration solution (ORS), coconut water, or clear soups to replace lost fluids and electrolytes.
• Eat light, easy-to-digest foods: Include bananas, rice, applesauce, and toast (BRAT diet) to help firm stools.
• Avoid fatty, spicy, or heavy foods: These can irritate the digestive system and worsen diarrhoea.
• Yogurt or probiotic foods: Helps restore healthy gut bacteria and improve digestion.
• Ginger or chamomile tea: Can soothe the stomach and reduce cramping.
• Avoid caffeine and alcohol: Both can worsen dehydration and irritate the intestines.
• Rest: Give your body time to recover while avoiding strenuous activity.

Dizziness Or Drowsiness

• Sit or lie down immediately when you feel dizzy to prevent falls.
• Hydrate well: Drink water, herbal teas, or electrolyte drinks; dehydration is a common cause of dizziness.
• Eat small, frequent meals: Low blood sugar can trigger light-headedness; include protein and complex carbs.
• Ginger: Consuming ginger tea or ginger chews may help reduce dizziness and nausea.
• Move slowly: Avoid sudden head movements or quick changes in posture.
• Focus on a fixed point: If spinning (vertigo), fix your gaze to reduce motion sensation.
• Limit caffeine, alcohol, and smoking: These can worsen dizziness.
• Balance exercises: Simple exercises like standing on one leg or walking heel-to-toe can improve stability over time.
• Rest and sleep well: Fatigue can make dizziness worse.

Indigestion

• Eat smaller, frequent meals: Avoid overeating; smaller portions reduce stomach strain.
• Chew food thoroughly: Helps proper digestion and reduces bloating.
• Avoid trigger foods: Limit spicy, fried, fatty, and carbonated foods that can worsen indigestion.
• Stay upright after meals: Wait at least 30–60 minutes before lying down to prevent acid reflux.
• Ginger: Sip ginger tea or chew a small piece to reduce bloating and nausea.
• Peppermint tea: Can relax the digestive tract and ease stomach discomfort.
• Fennel seeds: Chewing fennel seeds or making fennel tea can relieve bloating and gas.
• Drink warm water: Helps digestion and reduces stomach heaviness.
• Moderate physical activity: Gentle walking after meals can stimulate digestion.

Warning & Precautions

Pregnancy

Contraindicated

Cardace Meto 2.5/25mg Tablet is not recommended for use in pregnant women as it may cause serious harm to the growing foetus. Therefore, inform your doctor before taking this medicine if you are pregnant, think you may be pregnant or planning to have a baby. If you accidentally become pregnant while undergoing therapy with Cardace Meto 2.5/25mg Tablet, inform your doctor immediately.

Breastfeeding

Contraindicated

Cardace Meto 2.5/25mg Tablet is not recommended for use in breast-feeding women. Therefore, consult your doctor before taking it. 

Driving and Using Machines

Use with Caution

Do not drive or operate any heavy tools or machines if you feel dizzy after taking Cardace Meto 2.5/25mg Tablet. 

Alcohol

Contraindicated

Avoid consumption of alcohol while taking Cardace Meto 2.5/25mg Tablet as it may severely decrease your blood pressure and make you feel dizzier or faint.

Kidney

Consult your doctor

Cardace Meto 2.5/25mg Tablet is not recommended for use in patients with severe kidney impairment (including dialysis or narrowing or renal arteries). It should be used with caution in patients with other kidney problems (including kidney transplantation). Therefore, consult your doctor before taking it. 

Liver

Use with Caution

Cardace Meto 2.5/25mg Tablet is not recommended for use in patients with liver failure. It should be used with caution in patients with other minor liver problems (such as liver cirrhosis). Therefore, consult your doctor before taking it. 

Allergy

Contraindicated

Do not take Cardace Meto 2.5/25mg Tablet if you are allergic to Metoprolol, Ramipril or to any other beta-blockers (such as propranolol, atenolol) or ACE inhibitors (such as captopril, enalapril, lisinopril). 

Lungs

Contraindicated

Cardace Meto 2.5/25mg Tablet is not recommended for use in patients with severe lung problems (such as asthma, COPD or any form of breathing difficulties). Therefore, consult your doctor before taking it. 

Heart Disease

Consult your doctor

Cardace Meto 2.5/25mg Tablet is not recommended for use in patients with severe heart problems (such as slow or irregular heartbeat, severe heart failure, recent heart attack). It should be used with caution in patients with other minor heart problems. Therefore, consult your doctor before taking it. 

Use In Pediatrics

Contraindicated

Cardace Meto 2.5/25mg Tablet is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before consumption. 

Use In Geriatrics

Use with Caution

Cardace Meto 2.5/25mg Tablet should be used with caution in elderly patients. Therefore, consult your doctor before taking it.

Other Warnings for CARDACE METO 2.5/25MG TABLET

Before taking Cardace Meto 2.5/25mg Tablet, inform your doctor if you:

• have a history of allergic reaction to insects
• have diabetes
• have psoriasis (an auto-immune skin disorder)
• have dry eyes
• have myasthenia gravis (severe muscle weakness)
• are scheduled for any upcoming surgery
• are severely dehydrated due to any recent sickness such as vomiting or diarrhoea
• have any autoimmune disease that affects the skin or collagen (Ex. lupus erythematosus, rheumatoid arthritis or scleroderma)
• have any desensitization management (used to reduce the effect of an allergy to bee or wasp stings)
• have high blood potassium levels

Who should not take CARDACE METO 2.5/25MG TABLET

Cardace Meto 2.5/25mg Tablet is not recommended for use if you:

• have diabetes with impaired kidney functions
• are in shock
• have unmanaged phaeochromocytoma (a tumour of adrenal gland)
• have metabolic acidosis (increased acidity in blood)
• have problems in blood circulation (such as Raynaud’s disease)
• have block in blood vessels
• have a type of angina called Prinzmetal’s angina
• have severe low blood pressure
• suffer from frequent episodes of low blood sugar levels

Safety Advice

• Take exactly as prescribed: Do not adjust the dose or stop the medicine without consulting your doctor.
• Monitor blood pressure and heart rate: Regular checks help avoid low blood pressure or slow heart rate.
• Watch for side effects: Dizziness, fatigue, or light-headedness are common. Seek medical advice if symptoms are severe or persistent.
• Avoid sudden posture changes: Stand up slowly to prevent dizziness or fainting.
• Check for allergies: Inform your doctor if you have a history of allergic reactions to ACE inhibitors or beta-blockers.
• Do not stop abruptly: Sudden discontinuation may cause rapid heartbeat or blood pressure spikes. Always follow your doctor’s guidance for tapering.

Diet and Lifestyle Advice

• Eat a heart-healthy diet: Focus on fruits, vegetables, whole grains, lean proteins, and healthy fats.
• Limit salt intake: Excess sodium can raise blood pressure; avoid processed and fast foods.
• Control sugar and refined carbs: Helps maintain healthy weight and reduces heart strain.
• Stay hydrated: Drink plenty of water; dehydration can worsen dizziness.
• Avoid caffeine excess: Too much coffee or energy drinks may increase heart rate and blood pressure.
• Exercise regularly: Moderate activities like walking, swimming, or cycling for 30 minutes most days help strengthen the heart.
• Maintain a healthy weight: Reduces blood pressure and the heart’s workload.
• Manage stress: Practices like meditation, yoga, or deep breathing can help control blood pressure.
• Avoid smoking: Smoking worsens heart and vascular health.
• Sleep well: Aim for 7–8 hours of quality sleep to support overall heart health.

1. Cardace Meto 2.5 Tablet vs Amlodac-M 5/2.5 Tablet

2. Cardace Meto 2.5 Tablet vs Ramace -M/Ramace 2.5Tablet

Drug - Drug interaction

1. Medicines that lower blood pressure (e.g., diuretics, other ACE inhibitors, ARBs, calcium channel blockers)

• Interaction: May cause excessive lowering of blood pressure, dizziness, fainting, or light-headedness.
• Management: Monitor blood pressure regularly. Your doctor may adjust doses to prevent hypotension. Rise slowly from sitting or lying positions.

2. Potassium supplements or potassium-sparing diuretics (e.g., spironolactone, triamterene)

• Interaction: May increase potassium levels (hyperkalaemia), which can affect heart rhythm.
• Management: Avoid unnecessary potassium supplements. Regularly monitor blood potassium levels.

3. Nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g., ibuprofen, naproxen)

• Interaction: May reduce the blood pressure-lowering effect and increase risk of kidney damage.
• Management: Use NSAIDs only under medical supervision. Monitor blood pressure and kidney function.

4. Other beta-blockers or anti-arrhythmic drugs (e.g., propranolol, amiodarone)

• Interaction: May cause slow heart rate (bradycardia), fatigue, or dizziness.
• Management: Monitor heart rate and blood pressure. Dose adjustments may be needed under doctor guidance.

5. Insulin or oral diabetes medicines (e.g., metformin, glibenclamide)

• Interaction: May affect blood sugar control; can mask low blood sugar symptoms like rapid heartbeat.
• Management: Monitor blood sugar frequently and adjust diabetes medications as needed under medical supervision.

6. Lithium

• Interaction: Ramipril may increase lithium levels, leading to toxicity.
• Management: Monitor lithium levels closely. Dose adjustments may be necessary.

7. Medicines that cause drowsiness (e.g., sleeping pills, antihistamines, anti-anxiety medicines, alcohol)

• Interaction: Taking these along with Cardace Meto 2.5 Tablet may increase dizziness, sleepiness, and reduce alertness.
• Management: Avoid alcohol and use sedatives or anti-allergy medicines cautiously under medical advice. Do not drive or operate machines if you feel too sleepy.

8. Sympathomimetic drugs (e.g., decongestants like pseudoephedrine)

• Interaction: May reduce the blood pressure-lowering effect of Cardace Meto.
• Management: Use with caution and monitor blood pressure regularly.

9. Digoxin

• Interaction: May increase the risk of slow heart rate due to additive effects with metoprolol.
• Management: Monitor heart rate and consult your doctor for possible dose adjustments.

Drug - Food interaction

1. High-potassium foods (e.g., bananas, oranges, tomatoes, spinach)

• Interaction: Ramipril can increase potassium levels in the blood. Eating too many high-potassium foods may lead to hyperkalaemia, which can affect heart rhythm.
• Management: Limit high-potassium foods if advised by your doctor. Regular blood tests may be needed to monitor potassium levels.

2. Grapefruit and grapefruit juice

• Interaction: Grapefruit may slightly affect the metabolism of metoprolol, leading to higher drug levels, which can cause dizziness or slow heart rate.
• Management: Avoid large amounts of grapefruit or grapefruit juice while taking Cardace Meto 2.5 Tablet.

3. Salty or high-sodium foods (e.g., processed snacks, pickles, fast food)

• Interaction: Excess salt can reduce the blood pressure-lowering effect of ramipril, making the medicine less effective.
• Management: Maintain a low-sodium diet to help control blood pressure and enhance the effectiveness of therapy.

4. Caffeine-rich foods or drinks (e.g., coffee, energy drinks)

• Interaction: Caffeine can temporarily increase blood pressure and heart rate, counteracting the effects of Cardace Meto 2.5 Tablet.
• Management: Limit caffeine intake and monitor your blood pressure regularly.

5. Licorice (natural or candy form)

• Interaction: Excess licorice may reduce the blood pressure-lowering effect and cause fluid retention.
• Management: Avoid excessive licorice consumption while taking Cardace Meto 2.5 Tablet.

6. Foods affecting blood sugar (for patients with diabetes)

• Interaction: Metoprolol may mask symptoms of low blood sugar, and diet can influence sugar levels.
• Management: Monitor blood sugar levels carefully and maintain a balanced diet to avoid hypoglycemia.

Synopsis

More Information

FAQs About CARDACE METO 2.5/25MG TABLET

References

1. KD. Tripathi. Anti-adrenergic drugs and Drugs for Glaucoma. Drugs affecting Renin-angiotensin system. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 148 & 503.

2. Martin H. Strauss, Alistair S. Hall & Krzysztof Narkiewicz. The Combination of Beta-Blockers and ACE Inhibitors Across the Spectrum of Cardiovascular Diseases. Cardiovascular Drugs and Therapy. SpringerLink. September 2021. [Accessed on 21st January 2026]

3. Mylan Pharmaceuticals Inc. Metoprolol succinate tablet, film coated, extended release. Dailymed.com. [Revised in August 2022] [Accessed on 21st January 2026] 

4. Sanofi Ltd. Cardace Meto. Ramipril & Metoprolol Succinate Extended-Release Tablets. [Revised in October 2021] [Accessed on 21st January 2026]

Useful Diagnostic Tests

• Kidney Function Test

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 21 Jan 2026 | 03:30 PM(IST)