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GTN Sorbitrate CR 2.6mg Tablet 30'S
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INTRODUCTION
GTN SORBITRATE CR 2.6MG TABLET contains Nitroglycerine that belongs to the group of medicines called Vasodilators. It is used for prevention of angina pectoris due to coronary artery disease.
Angina is a type of chest pain which is caused by reduced blood flow to the heart as a result of coronary artery disease. Symptoms are feeling pressure, squeezing, heaviness, tightness or pain in the chest or a heavy weight is lying on the chest.
Along with GTN SORBITRATE CR 2.6MG TABLET your doctor may advise you to make certain lifestyle changes such as quitting alcohol and smoking, eating a healthy diet, manage weight and to improve your sleep pattern.
GTN SORBITRATE CR 2.6MG TABLET is not recommended for use in patients having heart diseases (hypertrophic obstructive cardiomyopathy), anaemia, raised pressure in head, raised pressure in the eye (glaucoma), or are taking medicines to treat erectile dysfunction (sildenafil, vardenafil, tadalafil.
GTN SORBITRATE CR 2.6MG TABLET should be used with caution in patients having liver or kidney diseases, underactive thyroid gland, low body temperature, malnourishment, abnormally low levels of oxygen in blood, very low blood pressure, low blood volume, disease of the blood vessels supplying the brain, or conditions that lower blood volume in the heart.
GTN SORBITRATE CR 2.6MG TABLET should be used with caution in pregnant and breast-feeding women. Take your doctor’s advice before taking the medicine. GTN SORBITRATE CR 2.6MG TABLET is not recommended for use in children. GTN SORBITRATE CR 2.6MG TABLET should be used with caution in elderly patients.
The most common side effects of taking GTN SORBITRATE CR 2.6MG TABLET are throbbing headache, spinning sensation, dizziness, drowsiness, lack of energy. Consult your doctor if the symptoms worsen or doesn’t improve.
USES OF GTN SORBITRATE CR 2.6MG TABLET
- It is used for prevention of angina pectoris due to coronary artery disease
HOW GTN SORBITRATE CR 2.6MG TABLET WORKS
GTN SORBITRATE CR 2.6MG TABLET causes relaxation of smooth muscles within blood vessels which leads to relaxation and widening of blood vessels. This improves blood supply to the heart muscles. As a result, it helps to relieve chest pain and blood pressure.
DIRECTIONS FOR USE
Always use GTN SORBITRATE CR 2.6MG TABLET exactly as prescribed by your doctor.
For Tablet, Capsule: Swallow GTN SORBITRATE CR 2.6MG TABLET with a glass of water. Do not crush or chew the medicine.
For Sublingual Tablet: Place GTN SORBITRATE CR 2.6MG TABLET inside your mouth, below the tongue and allow it to dissolve completely. Do not swallow or chew the medicine.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of disease condition. Continue to take GTN SORBITRATE CR 2.6MG TABLET for the stipulated duration prescribed by your doctor to achieve better results.
SIDE EFFECTS OF GTN SORBITRATE CR 2.6MG TABLET
COMMON
- throbbing headache
- spinning sensation
- fall in blood pressure when seated or standing up
- dizziness, drowsiness
- lack of energy
UNCOMMON
- fainting
- facial flushing
- nausea, vomiting
- localised burning sensation
- tongue blistering
- circulatory collapse
RARE
- restlessness
- heartburn
- bad breath, red, itchy, or flaky skin, skin rash
Stop taking GTN SORBITRATE CR 2.6MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- worsening of angina symptoms, chest pain
- signs of hypoxaemia (low levels of oxygen in blood) (difficulty breathing, increased rate of breathing)
- signs of methemoglobinemia (breathing problems, tiredness, headache)
- difficulty breathing, bluish discolouration of the lips, fingers or toes (cyanosis)
- rapid or slowed heartbeat
- blindness in one eye
- cerebral ischaemia (impaired blood flow to brain) which may cause weakness in one leg or arm, or weakness in one entire side of the body
- difficulty speaking, slurred speech
- loss of coordination, loss of consciousness
- allergic skin reactions
HOW TO MANAGE SIDE EFFECTS
Nausea:
Take this medicine with or after meals. Stick to simple meals while taking this medicine. Avoid eating rich or spicy food. Do not consume any medication by yourself. Take your doctor’s advice if nausea doesn’t improve or worsen.
Headache:
Try to take rest and do not involve yourself in exertive activities. Rest in a quiet and dark room. Apply a pain-relieving balm on your forehead. Take your doctor’s advice if headache doesn’t improve.
Vomiting:
Drink clear or ice-cold drinks. Eat bland, light foods and avoid fried, oily, or sweet foods. Avoid carbonated drinks. Take your doctor’s advice if vomiting doesn’t improve.
Dizziness:
Lie, or sit down immediately when you feel dizzy. If you're feeling severe episode of spinning(vertigo), lie in a dark and quite place with eyes closed. Try to avoid vehicle driving. Take your doctor’s advice if dizziness doesn’t improve.
Drowsiness:
Take adequate sleep. Do not involve in rigorous activities. Do not interfere with your sleep cycle. Talk to your doctor if the drowsiness doesn’t improve.
WARNING & PRECAUTIONS
PREGNANCY
GTN SORBITRATE CR 2.6MG TABLET should be used with caution in pregnant women. Consult your doctor before taking GTN SORBITRATE CR 2.6MG TABLET.
BREASTFEEDING
GTN SORBITRATE CR 2.6MG TABLET should be used with caution in breastfeeding women. Consult your doctor before taking GTN SORBITRATE CR 2.6MG TABLET.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you feel dizzy after taking GTN SORBITRATE CR 2.6MG TABLET.
ALCOHOL
Avoid consumption of alcohol during the treatment with GTN SORBITRATE CR 2.6MG TABLET as it may increase some effects of the medicine.
KIDNEY
GTN SORBITRATE CR 2.6MG TABLET should be taken with caution in patients with severe kidney disease. Consult your doctor before taking it.
LIVER
GTN SORBITRATE CR 2.6MG TABLET should be used with caution in patients with severe liver disease. Consult your doctor before taking it.
ALLERGY
Do not take GTN SORBITRATE CR 2.6MG TABLET if you are allergic to Nitroglycerine or any other components of this medicine.
HEART DISEASE
GTN SORBITRATE CR 2.6MG TABLET is not recommended for use in patients having heart diseases such as hypertrophic obstructive cardiomyopathy (thickening of heart muscles). GTN SORBITRATE CR 2.6MG TABLET should be used with caution in patients having other heart diseases such as have had a recent heart attack, narrowing of heart valves, inflammation of heart, heart failure or fluid build-up around the heart. Consult your doctor before taking GTN SORBITRATE CR 2.6MG TABLET.
OTHERS
GTN SORBITRATE CR 2.6MG TABLET is not recommended for use if you:
- have anaemia
- have raised pressure in head (including that caused by an accident)
- bleeding on brain (pain in eyes, changes in vision, bad headache behind the eyes)
- raised pressure in the eye
Before taking GTN SORBITRATE CR 2.6MG TABLET inform your doctor if you have:
- underactive thyroid gland
- low body temperature
- malnutrition (poor nutrition due to digestion problem or imbalanced diet)
- abnormally decreased levels of oxygen in the blood
- severely low blood pressure
- low blood volume
- conditions that lower the blood volume in the heart
- cerebrovascular diseases (diseases affecting the blood vessels supplying the brain)
Use in paediatrics:
GTN SORBITRATE CR 2.6MG TABLET is not recommended for use in children. Ask for the advice of your child’s doctor before giving it to your child.
Use in geriatrics:
GTN SORBITRATE CR 2.6MG TABLET should be used with caution in elderly patients. Ask for your doctor’s advice before taking the medicine.
INTERACTIONS
A. Drug-Drug interactions:
Before taking GTN SORBITRATE CR 2.6MG TABLET, inform your doctor if you are taking any of the following medicine:
- medicines for erectile dysfunction (male impotence) (Ex. sildenafil, vardenafil, tadalafil)
- medicines used to treat paracetamol overdose (Ex. n-acetylcysteine)
- medicines for migraine (Ex. ergotamine)
- other nitrates used to treat heart diseases (Ex. isosorbide dinitrate, isosorbide mononitrate, disopyramide), high blood pressure (Ex. ramipril, atorvastatin)
- medicines used for thinning your blood and prevent blood clots (Ex. warfarin)
- medicines used to treat Parkinson’s disease (Ex. apomorphine)
- medicines used to treat stomach ulcers (Ex. propantheline)
- medicines used to treat anxiety and depression (Ex. amitriptyline, isocarboxazid)
Overdosage:
If you or anyone else uses too much of GTN SORBITRATE CR 2.6MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage of GTN SORBITRATE CR 2.6MG TABLET may include nausea, low blood pressure, restlessness, fainting, blue coloration of the skin, methaemoglobin in the blood, breathing difficulties, lack of oxygen in tissues, slow heartbeat or mental illness.
SYNOPSIS
| Drug | : | Nitroglycerin (Glyceryl trinitrate) |
| Pharmacological Category | : | Vasodilators |
| Therapeutic Indication | : | Angina pectoris |
| Dosage Forms | : | Tablet, Capsule, Sublingual Tablet, Injection, Patch, Spray |
MORE INFORMATION
- Keep GTN SORBITRATE CR 2.6MG TABLET out of reach in children
- Store GTN SORBITRATE CR 2.6MG TABLET at room temperature below 25°C
FAQs ABOUT GTN SORBITRATE CR 2.6MG TABLET
Q: Why is GTN SORBITRATE CR 2.6MG TABLET prescribed?
A: GTN SORBITRATE CR 2.6MG TABLET is used for prevention of angina pectoris due to coronary artery disease. Angina is a type of chest pain which is caused by reduced blood flow to the heart as a result of coronary artery disease. Symptoms are feeling pressure, squeezing, heaviness, tightness or pain in the chest or a heavy weight is lying on the chest.
Q: Can GTN SORBITRATE CR 2.6MG TABLET be used in elderly patients?
A: GTN SORBITRATE CR 2.6MG TABLET should be used with caution in elderly patients. Take the medicines sat down to reduce possible low blood pressure or fainting. Your doctor may change the dose to suit your condition. If you notice that GTN SORBITRATE CR 2.6MG TABLET is not working as well at relieving pain as they have done, contact your doctor.
Q: How to use GTN SORBITRATE CR 2.6MG TABLET?
A: Always use GTN SORBITRATE CR 2.6MG TABLET exactly as prescribed by your doctor.
For Tablet, Capsule: Swallow GTN SORBITRATE CR 2.6MG TABLET with a glass of water. Do not crush or chew the medicine.
For Sublingual Tablet: Place GTN SORBITRATE CR 2.6MG TABLET inside your mouth, below the tongue and allow it to dissolve completely. Do not swallow or chew the medicine.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of disease condition. Continue to take GTN SORBITRATE CR 2.6MG TABLET for the stipulated duration prescribed by your doctor to achieve better results.
Q: Can GTN SORBITRATE CR 2.6MG TABLET cause headache?
A: Yes. GTN SORBITRATE CR 2.6MG TABLET can cause throbbing headache. If it happens, try to take rest and do not involve yourself in exertive activities. Rest in a quiet and dark room. Apply a pain-relieving balm on your forehead. Do not consume any medication without consulting a doctor. Take your doctor’s advice if headache doesn’t improve.
Q: Is it safe to consume alcohol while being treated with GTN SORBITRATE CR 2.6MG TABLET?
A: You are advised not to drink alcohol with GTN SORBITRATE CR 2.6MG TABLET, as some of the effects of this medicine are increased such as dizziness. If you have a habit of drinking alcohol, take your doctor’s advice before taking GTN SORBITRATE CR 2.6MG TABLET.
Q: Can GTN SORBITRATE CR 2.6MG TABLET affect my ability to drive?
A: As GTN SORBITRATE CR 2.6MG TABLET can cause dizziness, you should make sure you are not affected before driving or operating machinery, especially if taken with alcohol. Do not drive or operate any machines if you feel dizzy after taking GTN SORBITRATE CR 2.6MG TABLET. You can resume doing your activities after you feel normal again.
REFERENCES
1. KD. Tripathi. Antianginal and Other Anti-ischaemic Drugs. Essentials of medical pharmacology. Eighth edition. 2019. Page – 588, 589.
2. Panel Donald, P.PageN, Aubrey Carson Clarence, A.Buhr, Paul E.Flinn, Clyde E, Wells Margaret, T.Randall. Stability Study of Nitroglycerin Sublingual Tablets. Science Direct. January 2016. [Accessed 10th October 2022] https://www.sciencedirect.com/science/article/abs/pii/S0022354915400085
3. T Winsor, H J Berger. Oral nitroglycerin as a prophylactic antianginal drug: clinical, physiologic, and statistical evidence of efficacy based on a three-phase experimental design. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. November 1975. [Accessed 10th October 2022] https://pubmed.ncbi.nlm.nih.gov/811102/
4. W Schneider, M Kaltenbach, B Stahl, W D Bussmann. Anti-anginal efficacy of oral nitroglycerin. A clinical double-blind study with dose-effect relationships. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. August 1984. [Accessed 10th October 2022] https://pubmed.ncbi.nlm.nih.gov/6430666/
5. Kyle H. Kim, Connor C. Kerndt, Ghufran Adnan, Derek J. Schaller. Statpearls. Nitroglycerin. NIH National Library of Medicine, National center for biotechnology information. November 202. [Accessed on 8th October 2022] https://www.ncbi.nlm.nih.gov/books/NBK482382/
6. Accord. Electronic Medicines Compendium (EMC); [Revised on October 2019] [Accessed 10th October 2022] https://www.medicines.org.uk/emc/files/pil.5827.pdf
7. Torrent Pharmaceuticals Ltd. Vasovin XL (Nitroglycerine). [Revised in February 2022]. [Accessed 10th October 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/1790.pdf
8. Leeford Healthcare. Caditril 6.4 (Nitroglycerine). [Accessed 10th October 2022] https://www.leeford.in/product/568/caditril-64
9. Leeford Healthcare. Caditril 2.6 (Nitroglycerine). [Accessed 10th October 2022] https://www.leeford.in/product/568/caditril-64
USEFUL DIAGNOSTIC TESTS
- ECG (electrocardiogram)
- Kidney Function Tests
- Liver Function Tests
- Chest Xray
AUTHOR DETAILS
Written By Dr. Priyanka Goel, BDS
Last updated on 25 Jan 2023 | 11:36 AM(IST)
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