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Introduction About GANFORT EYE DROPS

GANFORT EYE DROPS is a combination of Bimatoprost and Timolol which belongs to the group of medicines called Prostaglandin analogs and Beta-blockers respectively. It is used to manage glaucoma and ocular hypertension.

Glaucoma is an eye condition that can cause vision loss and blindness by damaging a nerve in the back of your eye called the optic nerve. Ocular hypertension is an elevated pressure within the eye without damage to any optic nerve and vision loss or blindness.

Before using GANFORT EYE DROPS inform your doctor if you have heart disease, liver disease, kidney disease or any other problems.

Pregnant and breastfeeding women should consult their doctors before using GANFORT EYE DROPS. Inform your doctor if you wear contact lenses before using GANFORT EYE DROPS.

The most common side effects of using GANFORT EYE DROPS are eye redness, burning, itching, stinging, irritation of the conjunctiva, eye pain, dry eye, eye irritation, watery eyes, swollen eyelids, and reduced vision. Contact your doctor if any of the side effects worsen.

Uses Of GANFORT EYE DROPS

It is used to manage:

glaucoma
ocular hypertension

How GANFORT EYE DROPS Works

GANFORT EYE DROPS works together by reducing the production of liquid and also increasing the amount of liquid that is drained. This reduces the pressure inside the eye.

How to use GANFORT EYE DROPS

Use GANFORT EYE DROPS as advised by your physician. It is for ophthalmic use only. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of GANFORT EYE DROPS

Common

eye redness
loss of fat in the eye region which can lead to deepening of your eyelid crease
sunken eye
drooping eyelid, tightening of the skin around your eye
burning, itching, stinging, irritation of the conjunctiva
sensitivity to light, eye pain, sticky eyes, dry eyes, feeling of something in the eye
small breaks in the surface of the eye with or without inflammation
blurred vision
redness and itching of the eyelids, hair growing around the eye, darkening of the eyelids, darker skin colour around the eyes
longer eyelashes, eye irritation, watery eyes, swollen eyelids, reduced vision
runny nose
headache

Uncommon

abnormal sensation in the eye
iris inflammation
painful eyelids, tired eyes, in-growing eyelashes
darkening of the iris colour
eyelid has moved away from the surface of the eye
darkening of eyelashes
shortness of breath

How To Manage Side Effects

Headache:

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume too much of alcohol. Consult your doctor if the symptom did not improve.

Warning & Precautions

Pregnancy

GANFORT EYE DROPS is generally not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before using it.

Breastfeeding

GANFORT EYE DROPS is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before using it.

Driving and Using Machines

Do not drive or operate any machines if you feel blurred vision, dizziness, eyesight problem, after using GANFORT EYE DROPS.

Alcohol

Consumption of alcohol is not recommended during management with GANFORT EYE DROPS.

Kidney

GANFORT EYE DROPS should be used with caution in patients with kidney problems. Consult your doctor before using.

Liver

GANFORT EYE DROPS should be used with caution in patients with liver problems. Consult your doctor before using.

Allergy

Do not use this medicine if you are allergic (hypersensitive) to Bimatoprost or Timolol or beta-blockers or any of the other ingredients of this medicine.

Lungs

GANFORT EYE DROPS is not recommended in patients with respiratory problems such as asthma, severe chronic obstructive pulmonary disease (lung disease which may cause wheeziness, difficulty in breathing and/or long-standing cough) or other types of breathing problems.

Heart Disease

GANFORT EYE DROPS is not recommended in patients with heart problems such as low heart rate, heart block, or heart failure. It must be used with caution in patients with coronary heart disease (symptoms can include chest pain or tightness, breathlessness or choking) and lower blood pressure. Consult your doctor before using.

Others

Before using GANFORT EYE DROPS, inform your doctor if you have:

poor blood circulation disease
overactivity of the thyroid gland
diabetes
eye surface problems
separation of one of the layers within the eyeball after surgery to reduce the pressure in the eye
severe allergic reactions
macular oedema (swelling of the retina within the eye leading to worsening vision)
other eye disorder
an operation, including minor surgery and dental work

Use in pediatrics:

GANFORT EYE DROPS is not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before using GANFORT EYE DROPS.

Use in geriatrics:

GANFORT EYE DROPS should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before using GANFORT EYE DROPS.

Interactions

A. Drug-Drug interactions:

Before using GANFORT EYE DROPS, inform your doctor if you are using any of the following medicine:

other eye drops (used to manage glaucoma)
medicines used to manage lower blood pressure
medicines used to manage heart problems
medicines used to manage diabetes
amiodarone, quinidine (used to manage heart conditions such as irregular or abnormal heartbeat and some types of malaria)
fluoxetine and paroxetine (used to manage depression)
guanethidine, reserpine (used to manage high blood pressure or heart disease)

Overdosage:

If you or anyone else uses much of GANFORT EYE DROPS, contact your doctor immediately or go to a nearby hospital.

Synopsis

Drug	:	Bimatoprost, Timolol
Pharmacological Category	:	Prostamides, Beta-blockers
Therapeutic Indication	:	Glaucoma, Ocular hypertension
Dosage Forms	:	Eye drops

More Information

Keep GANFORT EYE DROPS out of reach of children
Store at room temperature

FAQs About GANFORT EYE DROPS

Can GANFORT EYE DROPS cause eye irritation?

Yes, this medicine may cause eye irritation in some individuals. Wear sunglasses when you go outside. Rinse your eye with preservative-free saline water or apply a cold, wet washcloths. Take out your contact lenses. Do not rub your eyes.

How does GANFORT EYE DROPS works?

GANFORT EYE DROPS works together by reducing the production of liquid also increasing the amount of liquid that is drained. This reduces the pressure inside the eye.

Is it safe to consume alcohol while using this medicine?

Consumption of alcohol is not recommended during management with GANFORT EYE DROPS. consult your doctor for advice.

Can I use GANFORT EYE DROPS during pregnancy?

No, GANFORT EYE DROPS is generally not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before using it.

References

1. KD. Tripathi. Antiadrenergic Drugs (Adrenergic Receptor Antagonists) and Drugs for Glaucoma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 155 & 148.

2. Safety and Efficacy of Bimatoprost Timolol Ophthalmic Solution in Patients with Open Angle Glaucoma or Ocular Hypertension. NIH: U.S. National Library of Medicine.ClinicalTrials.gov.17 Apr 2019. [Accessed on 21 Apr 2022] https://clinicaltrials.gov/ct2/show/NCT01068964

3. Monique P Curran 1, Jennifer S Orman. Bimatoprost/timolol: a review of its use in glaucoma and ocular hypertension. NIH: National Library of Medicine, National Library of Medicine. PubMed. Gov.2009. [Accessed on 21 Apr 2022] https://pubmed.ncbi.nlm.nih.gov/19220073/

4. Mims.com. Bimatoprost+Timolol – Ophthalmic. [Accessed on 21 Apr 2022] https://www.mims.com/philippines/drug/info/bimatoprost%20+%20timolol/patientmedicine/bimatoprost%252Btimolol%2B-%2Bophthalmic

5. RAFARM S.A; Electronic Medicines Compendium (EMC). [Revised on Jan 2022] [Accessed on 21 Apr 2022] https://www.medicines.org.uk/emc/files/pil.12468.pdf

6. Allergan Pharmaceuticals Ireland. [Accessed on 21 Apr 2022] https://www.ema.europa.eu/en/documents/product-information/ganfort-epar-product-information_en.pdf

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Purvi Raghuvanshi - MBBS, ENT

Last updated on 10 Dec 2022 | 02:44 PM(IST)