ZYMOTRIP DP Tablet 10's

Introduction About ZYMOTRIP DP TABLET

ZYMOTRIP DP TABLET is a combination of Diclofenac, Paracetamol and Trypsin Chymotrypsin which belongs to the group of medicines called Non-Steroidal Anti-inflammatory agents (NSAIDs), Analgesics and Proteolytic Enzymes respectively. It is used to relieve various forms of pain and inflammation in conditions such as surgical trauma, fracture and dislocation, post traumatic oedema, post-operative wounds, gynaecological inflammatory conditions, ENT inflammatory conditions and dental inflammatory conditions.

Avoid smoking and consuming alcohol during the management with ZYMOTRIP DP TABLET. It is not recommended for use in patients having liver, kidney, heart, lung diseases, active stomach or intestinal ulcer, bleeding or perforation of the gastrointestinal tract, gastric hemorrhage, and increased eye pressure. ZYMOTRIP DP TABLET should be used with caution in patients who have ulcerative colitis, Crohn’s disease, systemic lupus erythematosus (SLE), hypertension, hyperlipidemia (increased cholesterol levels), diabetes mellitus and clotting disorders.

ZYMOTRIP DP TABLET is not suitable for use in pregnant women. There is limited studies available on the use of this medicine in breastfeeding women. Caution must be exercised while taking ZYMOTRIP DP TABLET in children and elderly patients. The most common side effects of taking ZYMOTRIP DP TABLET are nausea, vomiting, diarrhoea, heartburn, stomach pain, indigestion, and loss of appetite. Consult your doctor’s advice if any of these above side effects worsen or persists for a longer duration.

Uses Of ZYMOTRIP DP TABLET

It is used to relieve pain and inflammation in conditions such as:

• surgical trauma
• fracture and dislocation
• post traumatic oedema
• post-operative wounds
• gynaecological inflammatory conditions
• ENT inflammatory conditions
• dental inflammatory conditions

How ZYMOTRIP DP TABLET Works

ZYMOTRIP DP TABLET helps in managing various pain and inflammatory condition where Diclofenac and Paracetamol works by reducing the effects of prostaglandin (substance produced during injury and inflammation causing pain) thereby blocking the pain signals between the brain and nerve endings. Trypsin Chymotrypsin is a combination of enzymes which break down proteins into smaller fragments, thereby making them available for absorption into the blood and increases blood supply in the affected area and reduce swelling. It also has analgesic effects and reduces the pain which is associated with healing.

How to use ZYMOTRIP DP TABLET

Take ZYMOTRIP DP TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of ZYMOTRIP DP TABLET depending on your age, body weight, and disease condition.

Side Effects Of ZYMOTRIP DP TABLET

How To Manage Side Effects

Diarrhea

Drink more fluids like water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own for diarrhea without consulting your doctor.

Nausea And Vomiting

Take this medicine with, or just after meals. Stick to simple meals. Drink clear or ice-cold drinks, eat light, bland foods and avoid fried, oily, or sweet foods. If the symptom not improved, consult with your doctor.

Stomach Pain

Try to rest and relax. Eat and drink slowly or try to have lesser and more frequent meals. Keep a heating pad on your stomach. If the symptom not improved, consult with your doctor.

Warning & Precautions

Pregnancy

Contraindicated

ZYMOTRIP DP TABLET is not recommended for use in pregnant women. Consult your doctor before taking it.

Breastfeeding

Consult your doctor

There is limited information on the use of ZYMOTRIP DP TABLET in breastfeeding women as it may pass into breast milk. Consult your doctor before taking it.

Driving and Using Machines

Use with Caution

Do not drive or use machineries if you feel visual disturbances, dizziness, vertigo, excessive sleepiness, or fatigue after taking ZYMOTRIP DP TABLET.

Alcohol

Contraindicated

Consumption of alcohol is not recommended while taking ZYMOTRIP DP TABLET as it may worsen the side effects.

Kidney

Contraindicated

ZYMOTRIP DP TABLET is not recommended for use in patients with severe kidney disease. Consult your doctor before taking.

Liver

Contraindicated

ZYMOTRIP DP TABLET is not recommended for use in patients with severe liver disease. Consult your doctor before taking.

Allergy

Contraindicated

Do not take ZYMOTRIP DP TABLET if you are allergic to Diclofenac, Paracetamol, Trypsin Chymotrypsin, or any other ingredients of this medicine.

Lungs

Contraindicated

ZYMOTRIP DP TABLET is not recommended for use in patients with lung diseases such as asthma. Consult your doctor before taking.

Use In Pediatrics

Consult your doctor

Your doctor will decide the correct dose and duration of the management with ZYMOTRIP DP TABLET depending on your child’s age, disease condition, and body weight. Consult your doctor.

Use In Geriatrics

Use with Caution

In elderly patients, ZYMOTRIP DP TABLET should be used with caution. Your doctor will decide the correct dose and duration of the management with ZYMOTRIP DP TABLET depending on your age, disease condition, and body weight. Consult your doctor.

Interactions

A. Drug-Drug Interactions:

Tell your physician if you are taking any of the following medicines before taking ZYMOTRIP DP TABLET:

• lithium (used to manage mental illness)
• citalopram (used to manage depression and anxiety)
• digoxin, furosemide, spironolactone, ramipril (used to manage heart problems)
• amiodarone (used to manage high blood pressure and chronic stable angina)
• ciclosporin, tacrolimus, trimethoprim (medicines that cause increased levels of potassium in the blood)
• warfarin, and heparin (used to manage blood clots or as blood thinners)
• celecoxib, corticosteroids such as prednisolone (used to manage pain and inflammation)
• metformin, sitagliptin (used to manage diabetes)
• methotrexate (used to manage cancer)
• ciprofloxacin, moxifloxacin (used to manage bacterial infection)
• phenytoin (used to manage fits)
• colestipol, cholestyramine (used to lower the cholesterol levels)
• mifepristone (used to terminate pregnancy)

Overdosage:

If you or anyone else accidentally takes too much of ZYMOTRIP DP TABLET, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep ZYMOTRIP DP TABLET out of reach of children
• Store below 25°C

FAQs About ZYMOTRIP DP TABLET

Q: What is ZYMOTRIP DP TABLET used for?

A: is a combination of Diclofenac, Paracetamol and Trypsin Chymotrypsin which belongs to the group of medicines called Non-Steroidal Anti-inflammatory agents (NSAIDs), Analgesics and Proteolytic Enzymes respectively. It is used to relieve various forms of pain and inflammation in conditions such as surgical trauma, fracture and dislocation, post traumatic oedema, post-operative wounds, gynaecological inflammatory conditions, ENT inflammatory conditions and dental inflammatory conditions.

Q: Is ZYMOTRIP DP TABLET safe to use in pregnant and breastfeeding women?

A: ZYMOTRIP DP TABLET is not recommended for use in pregnant women. There is limited information on the use of ZYMOTRIP DP TABLET in breastfeeding women as it may pass into breast milk. Consult your doctor before taking it.

Q: Can ZYMOTRIP DP TABLET impair my ability to drive?

A: ZYMOTRIP DP TABLET may cause certain side effects that may affect driving ability. Do not drive or use machines if you feel visual disturbances, dizziness, vertigo, excessive sleepiness, or fatigue after taking ZYMOTRIP DP TABLET.

Q: Can ZYMOTRIP DP TABLET be used in children?

A: Your doctor will decide the correct dose and duration of the management with ZYMOTRIP DP TABLET depending on your child’s age, disease condition, and body weight. Consult your doctor.

Q: What are the most common side effects of ZYMOTRIP DP TABLET?

A: The most common side effects of taking ZYMOTRIP DP TABLET are nausea, vomiting, diarrhea, heartburn, stomach pain, indigestion and loss of appetite. Consult your doctor’s advice if any of these worsen or don’t improve.

References

1. KD. Tripathi. Nonsteroidal Anti-inflammatory Drugs and Antipyretic-Analgesics. Essentials of medical pharmacology. Eighth edition. 2019. Page –204, 206.

2. Shah D, Mital K. The Role of Trypsin: Chymotrypsin in Tissue Repair. NIH National Library of Medicine, National center for biotechnology information. PubmedCentral. January 2018. [Accessed on 9th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778189/

3. NIH National Library of Medicine, National center for biotechnology information. Pubchem. Diclofenac Sodium. [Accessed on 9th July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Diclofenac-sodium

4. Torrent Pharmaceuticals Ltd. Chymoral Forte. [Revised in August 2017] [Accessed on 9th July 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2618.pdf

5. Cassopeia Pharma. Chymocas-D. [Accessed on 11th August 2022] https://www.cassopeiapharma.com/product/chymocas-d

6. Medilon Healthcare. Tryflam. [Accessed on 11th August 2022] http://www.medilonhealthcare.com/trypsin-chymotrypsin-50-000-armour-units-diclofenac-potassium-50-mg-paracetamo-325-mg-4626580.html

7. BSA Pharma Inc. Inflabis-D. [Accessed on 11th August 2022] https://www.bsapharmainc.in/trypsinchymotrypsin-diclofenac-potassium-paracetamol/

8. MK Medicine. Diclofenac potassium, Paracetamol, and Trypsin Chymotrypsin. [Accessed on 11th August 2022] https://www.mkmedicine.in/trypsin-chymotrypsin-50,000-armour-units-diclofenac-potassium-50mg-paracetamol-325mg-tablet.html

9. Ikon remedies. [Accessed on 11th August 2022] https://www.ikonremedies.com/product/chymowin-dp-tablets/

Useful Diagnostic Tests

• Complete blood count

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Sankara Babu Gorle - MBBS, MD (Pharmacology)

Last updated on 04 Mar 2023 | 10:54 PM(IST)