Zoxakind Oral Suspension 30ml

Introduction About ZOXAKIND ORAL SUSPENSION

ZOXAKIND ORAL SUSPENSION contains Nitazoxanide which belongs to the group of medicines called Antiprotozoals. It is used to manage diarrhoea caused by Giardia lamblia or Cryptosporidium parvum. Diarrhoea occurs when not enough water is removed from the stool, or too much fluid is secreted into the stool, making it loose.

Avoid consumption of alcohol while taking this medicine. ZOXAKIND ORAL SUSPENSION is not effective for the management of diarrhoea caused by C. parvum in HIV-infected or immunodeficient patients. Before taking ZOXAKIND ORAL SUSPENSION, inform your doctor if you have diabetes, kidney, liver, biliary problems.

ZOXAKIND ORAL SUSPENSION should be used with caution among pregnant women and breastfeeding women as safety data has not been established yet. Safety and effectiveness of ZOXAKIND ORAL SUSPENSION in children below 1 year of age has not been established yet. It should be used with caution in elderly patients above 65 years of age.

The most common side effects of taking ZOXAKIND ORAL SUSPENSION are abdominal pain, diarrhoea, headache, and nausea. Contact your doctor if any of the above symptoms worsen.

Uses Of ZOXAKIND ORAL SUSPENSION

• to manage diarrhea caused by Giardia lamblia or Cryptosporidium parvum

How ZOXAKIND ORAL SUSPENSION Works

ZOXAKIND ORAL SUSPENSION works by disturbing the energy metabolism in anaerobic microbes. It changes the structure of protozoa cell membranes, mitochondrial membranes, and stops viral replication. Thus killing the protozoa causing diarrhoea.

How to use ZOXAKIND ORAL SUSPENSION

Take ZOXAKIND ORAL SUSPENSION as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.

Side Effects Of ZOXAKIND ORAL SUSPENSION

How To Manage Side Effects

Headache: 

Rest and relax. Keep yourself hydrated by drinking more fluids such as water or electrolytes. If needed apply a pain-relieving balm on the forehead. Avoid consumption of alcohol. If the symptom does not improve, contact your physician for advice.

Nausea:

Stick to simple meals. Avoid eating oil-rich or spicy foods. If the symptom does not improve, contact your physician for advice.

Diarrhoea:

Drink more fluids like water or fruit juice to keep yourself hydrated. Do not take any medicine on your own for diarrhoea without consulting your physician. If the symptom does not improve, contact your physician for advice.

Stomach pain:

Rest and relax. Eat and drink slowly or try to have lesser and more frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your physician for advice.

Warning & Precautions

Pregnancy

ZOXAKIND ORAL SUSPENSION should be used with caution in pregnant women or women planning to have a baby as safety data has not been established yet. Consult your doctor before taking it.

Breastfeeding

ZOXAKIND ORAL SUSPENSION should be used with caution in breastfeeding women as it is not known if it is excreted in breastmilk. Your doctor will weigh the potential benefits against the potential risks. Consult your doctor before taking it.

Alcohol

Avoid consumption of alcohol while taking ZOXAKIND ORAL SUSPENSION.

Kidney

ZOXAKIND ORAL SUSPENSION should be used with caution in patients with kidney problems as safety data has not been established yet. Consult your doctor before taking it.

Liver

ZOXAKIND ORAL SUSPENSION should be taken with caution in patients with liver problems as safety data has not been established yet. Consult your doctor before taking it.

Allergy

Do not take ZOXAKIND ORAL SUSPENSION if you are allergic to Nitazoxanide or any of the other ingredients of this medicine.

Interactions

A. Drug-Drug interactions:

Before taking ZOXAKIND ORAL SUSPENSION, inform your doctor if you are taking any of the following medicine:

• medicines used to manage or manage blood clots (Ex. warfarin)

Overdosage:

If you or anyone else accidentally took more of ZOXAKIND ORAL SUSPENSION, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep ZOXAKIND ORAL SUSPENSION out of reach of children
• Store at room temperature

FAQs About ZOXAKIND ORAL SUSPENSION

What is ZOXAKIND ORAL SUSPENSION used for?

ZOXAKIND ORAL SUSPENSION is used to manage diarrhoea caused by Giardia lamblia or Cryptosporidium parvum. Diarrhoea occurs when not enough water is removed from the stool, or too much fluid is secreted into the stool, making it loose.

Can ZOXAKIND ORAL SUSPENSION cause headaches?

Yes. Headache is one of the most common side effects of taking ZOXAKIND ORAL SUSPENSION. In case your child is experiencing a headache after taking ZOXAKIND ORAL SUSPENSION, rest and relax. Keep hydrated by drinking more fluids such as water or electrolytes. If needed apply a pain-relieving balm on the forehead. Avoid consumption of a. If the symptoms do not improve please consult your doctor.

What precaution is to be taken before taking ZOXAKIND ORAL SUSPENSION?

ZOXAKIND ORAL SUSPENSION should be used with caution in lactating and in children below 1 year of age. ZOXAKIND ORAL SUSPENSION should be used with caution in patients who have renal problems, hepatic problems, pregnant women, and elderly patients. Please consult your doctor before taking ZOXAKIND ORAL SUSPENSION.

Does ZOXAKIND ORAL SUSPENSION change urine colour?

Yes, ZOXAKIND ORAL SUSPENSION may change the colour of urine. This is normal and not harmful. if symptoms do not improve or get worse consult your doctor immediately.

How does ZOXAKIND ORAL SUSPENSION work?

ZOXAKIND ORAL SUSPENSION works by disturbing the energy metabolism in anaerobic microbes. It changes the structure of protozoa cell membranes, mitochondrial membranes, and stops viral replication. Thus killing the protozoa causing diarrhoea. 

References

1. KD. Tripathi. Antiamoebic and Other Antiprotozoal Drugs. Drugs Essentials of medical pharmacology. Seventh edition. 2013. Page – 840-841.

2. Mohammad Rashidul Hashan, Khaled Mosaad Elhusseiny, Le Huu-Hoaiz, Thuan Minh Tieu , Soon Khai Low et.al. Effect of nitazoxanide on diarrhea: A systematic review and network meta-analysis of randomized controlled trials. Journal of Acta Tropica. Science direct. October 2020 [Accessed on 10th August 2022] https://www.sciencedirect.com/science/article/abs/pii/S0001706X19316328?via%3Dihub

3. Samarendra Mahapatro, Nijwm Mahilary, Amit Kumar Satapathy, and Rashmi Ranjan Das. Nitazoxanide in Acute Rotavirus Diarrhea: A Randomized Control Trial from a Developing Country. NIH. National Library of Medicine, National Center for Biotechnology information. Pubmed Central. February 2017 [Accessed on 10th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346365/

4. Romark Pharmaceuticals. US Food and Drug Administration. [Revised in June 2005] [Accessed on 10th August 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021818lbl.pdf

5. Romark Pharmaceuticals. ALINIA Tablets and Oral suspension. [Revised in April 2017] [Accessed on 10th August 2022] https://www.alinia.com/wp-content/uploads/2017/08/prescribing-information.pdf

6. Nitazoxanide. Mayoclinic. [Revised in November 2022] [Accessed on 10th August 2022] Nitazoxanide (Oral Route) Proper Use - Mayo Clinic

Useful Diagnostic Tests

• Stool Examination

Author Details

Written By Dr. Shruthi M R - BDS

Reviewed For Accuracy By Dr. Salem Gill - MBBS

Last updated on 13 Jan 2023 | 05:06 PM(IST)