Zoflut 0.05% Ointment 10gm

Introduction About ZOFLUT 0.05% OINTMENT

ZOFLUT 0.05% OINTMENT contains Fluticasone Furoate which belongs to the group of medicines called Corticosteroids (glucocorticoids). It is used to manage inflamed skin, redness and itching in several skin problems not caused by germs and responsive to corticosteroids such as eczema, dermatitis, or insect bites.

ZOFLUT 0.05% OINTMENT is not recommended for use in patients having other skin problems such as acne, severe flushing of skin on and around your nose (rosacea), spotty red rash around your mouth (perioral dermatitis), itching around your back passage or private parts, infected skin, which is not being managed, and itchy skin which is not inflamed.

Before using ZOFLUT 0.05% OINTMENT inform your doctor if you have broken or damaged skin, chronic leg ulcer, psoriasis, or you need to use ZOFLUT 0.05% OINTMENT on face. ZOFLUT 0.05% OINTMENT should be used with caution in pregnant and breastfeeding women.

ZOFLUT 0.05% OINTMENT is not recommended for use in infants below 3 months of age and should be used with caution in children below 12 years of age. Ask for the advice of your child’s doctor before using ZOFLUT 0.05% OINTMENT for your child.

Avoid smoking or going near a naked flame while using ZOFLUT 0.05% OINTMENT as this poses a risk of severe burns. The most common side effects of using ZOFLUT 0.05% OINTMENT include irritation or itching. Contact your doctor if any of these side effects worsen or doesn’t improve.

Uses Of ZOFLUT 0.05% OINTMENT

• it is used to manage inflamed skin, redness and itching in several skin problems not caused by germs and responsive to corticosteroids such as eczema, dermatitis, or insect bites

How ZOFLUT 0.05% OINTMENT Works

ZOFLUT 0.05% OINTMENT causes vasoconstriction (constriction of blood vessels) and has an anti-inflammatory activity. It directly decreases the cells that cause inflammation such as eosinophils, monocytes, mast cells, macrophages, and dendritic cells. Therefore, helping in reducing the inflammation and redness.

How to use ZOFLUT 0.05% OINTMENT

Always use ZOFLUT 0.05% OINTMENT as directed by your physician. It is for external use only. Dry the infected part of the skin before using ZOFLUT 0.05% OINTMENT. Wash your hands before and after using this medicine. Do not let ZOFLUT 0.05% OINTMENT go into your eye and do not apply on mucous membranes. Your doctor will decide the correct dose, duration, and frequency of the medicine for you depending on your existing conditions, weight and age.

Side Effects Of ZOFLUT 0.05% OINTMENT

How To Manage Side Effects

Itchy skin:

Hot water makes your skin irritated, so avoid taking hot showers. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. To soothe and hydrate the irritated skin, apply moisturizers. Contact your doctor if itching worsens.

Warning & Precautions

Pregnancy

ZOFLUT 0.05% OINTMENT should be used with caution in pregnant women only if the expected benefit to the mother is greater than any possible risk to the foetus. Contact your doctor before using.

Breastfeeding

ZOFLUT 0.05% OINTMENT should be used with caution in breastfeeding women only if the expected benefit to the mother is greater than any possible risk to the child. Contact your doctor before using.

Driving and Using Machines

ZOFLUT 0.05% OINTMENT is unlikely to affect your ability to drive and use machines.

Allergy

Do not use ZOFLUT 0.05% OINTMENT if you are allergic to Fluticasone or any of the other ingredients of this medicine.

Interactions

A. Drug-Drug Interactions:

Before using ZOFLUT 0.05% OINTMENT, tell your doctor if you are taking, or have recently taken any of the following medicines:

• medicines used to manage HIV (Ex. ritonavir, cobicistat)

Overdosage:

If you or anyone else apply too much or have accidental ingestion and systemic exposure of ZOFLUT 0.05% OINTMENT, consult your doctor immediately or visit the nearby hospital as it can make you ill.

Synopsis

More Information

• Keep ZOFLUT 0.05% OINTMENT out of sight and reach of children.
• Store ZOFLUT 0.05% OINTMENT at room temperature below 30°C

FAQs About ZOFLUT 0.05% OINTMENT

What is ZOFLUT 0.05% OINTMENT and why is it prescribed?

ZOFLUT 0.05% OINTMENT contains Fluticasone Furoate which belongs to the group of medicines called Corticosteroids (glucocorticoids). It is used to manage inflamed skin, redness and itching in several skin problems not caused by germs and responsive to corticosteroids such as eczema, dermatitis, or insect bites.

Is ZOFLUT 0.05% OINTMENT a steroid?

Yes, ZOFLUT 0.05% OINTMENT is corticosteroid which vasoconstriction (constriction of blood vessels) and has an anti-inflammatory activity. It directly decreases the cells that cause inflammation such as eosinophils, monocytes, mast cells, macrophages, and dendritic cells. Therefore, helping in reducing the inflammation and redness.

What other precautions should be taken while using ZOFLUT 0.05% OINTMENT?

Before applying ZOFLUT 0.05% OINTMENT tell your doctor if you have previously had an allergic reaction with another steroid, been applying the ointment under an airtight dressing, including a child’s nappy, been applying the ointment on broken or damaged skin or within skin folds, been applying to a large surface area. Contact your doctor before using ZOFLUT 0.05% OINTMENT.

Can ZOFLUT 0.05% OINTMENT be applied on face?

You should only apply ZOFLUT 0.05% OINTMENT to your face if your doctor tells you to. ZOFLUT 0.05% OINTMENT should not be used for too long as the skin on your face thins easily. Do not let the ointment get into your eyes as cataracts or glaucoma may be caused if the ointment repeatedly enters the eye. Contact your doctor before using ZOFLUT 0.05% OINTMENT.

Can I stop using ZOFLUT 0.05% OINTMENT on my own if I start to feel better?

Do not stop using ZOFLUT 0.05% OINTMENT until and unless your doctor asks you to. It is important that ZOFLUT 0.05% OINTMENT is not stopped suddenly as this may relapse your present condition or make it worse. Ask for your doctor’s advice if you wish to discontinue using ZOFLUT 0.05% OINTMENT.

References

1. K.D. Tripathi. Respiratory System Drugs. Essentials of Medical Pharmacology. Eighth Edition. 2019. Page 250.

2. Sheila fallon Friedlander, Adelaide A Hebert, D.B. Allen. Safety of fluticasone propionate cream 0.05% for the treatment of severe and extensive atopic dermatitis in children as young as 3 months. Journal of the American Academy of Dermatology. Research Gate. March 2022. [Accessed on 2nd November 2022] https://www.researchgate.net/publication/11500199_Safety_of_fluticasone_propionate_cream_005_for_the_treatment_of_severe_and_extensive_atopic_dermatitis_in_children_as_young_as_3_months

3. Kailey Remien, Andy Bowman. Fluticasone. NIH National Library of Medicine, National center for biotechnology information. StatPearls. June 2022. [Accessed on 2nd November 2022] https://www.ncbi.nlm.nih.gov/books/NBK542161/

4. Glaxo Operations UK Ltd. Electronic Medicines Compendium (EMC). [Revised in Mar 2022] [Accessed on 2nd Nov 2022] https://www.medicines.org.uk/emc/files/pil.937.pdf

5. Salvat Laboratorios. Electronic Medicines Compendium (EMC). [Revised in Aug 2021] [Accessed on 2nd Nov 2022] https://www.medicines.org.uk/emc/files/pil.9364.pdf

6. Cosette Pharmaceuticals, Inc. Dailymed. [Revised in Apr 2022] [Accessed on 2nd Nov 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=a9a168b2-42de-48aa-9970-23b0a63ad3f8&type=display

Useful Diagnostic Tests

• Percutaneous skin test
• Allergen-specific immunoglobulin E (IgE) antibody test

Author Details

Written By Dr. Priyanka Goel - BDS

Reviewed For Accuracy By Dr. Karthikeyan Rajagopal - M. Pharma, Ph.D (Pharmacology)

Last updated on 10 Nov 2022 | 12:58 PM(IST)