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Introduction About ZIMPOMET TABLET
ZIMPOMET TABLET is used to manage type II diabetes mellitus when diet and exercise alone does not result in adequate blood sugar control. It contains Metformin which belongs to the group of medicines called Anti-diabetic agents. It makes the body more sensitive to insulin (a hormone involved in glucose metabolism). This helps our body cells to utilize more amount of the circulating blood glucose, thereby reducing blood sugar levels. Additionally, it also manages glucose production by the liver and reduces its absorption in the body.
Along with the therapy, your doctor might ask you to make certain lifestyle changes such as following a healthy diet, regular physical exercise and quitting alcohol consumption. Before taking ZIMPOMET TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have any severe systemic infections or are severely dehydrated due to excessive vomiting or diarrhea recently.
ZIMPOMET TABLET is not recommended for use in patients with severe uncontrollable diabetes. It is also not suitable for use in patients with shock or problems with breathing or blood circulation. Consult your doctor before taking ZIMPOMET TABLET if you are pregnant or breastfeeding. The most common side effects are stomach upset and diarrhea. These side effects can be controlled when the medicine is taken along with meals. However, if these side effect bothers you or worsens contact your doctor.
Uses Of ZIMPOMET TABLET
- Used to manage type II diabetes mellitus
How ZIMPOMET TABLET Works
ZIMPOMET TABLET makes the body more sensitive to insulin (a hormone involved in glucose metabolism). This helps our body cells to utilize more amount of the circulating blood glucose, thereby reducing blood sugar levels. Additionally, it also manages glucose production by the liver and reduces its absorption in the body.
How to use ZIMPOMET TABLET
- Take ZIMPOMET TABLET preferably after meals or as advised by your physician
- Swallow the medicine with a glass of water. Do not crush or chew the medicine
- Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition
- Do not stop taking ZIMPOMET TABLET unless your doctor advice you to stop
Side Effects Of ZIMPOMET TABLET
Common side effects of ZIMPOMET TABLET:
- diarrhea, stomach pain, loss of appetite
- changes in taste, metallic taste
Stop taking ZIMPOMET TABLET and consult your doctor immediately if you experience any of the following side effects:
- serious allergic reaction (such as hives, swelling of the face, lips, tongue or throat causing difficulty in breathing or swallowing)
- signs of liver problems (such as nausea or vomiting, stomach pain, unusual or unexplained tiredness, loss of appetite, dark urine, yellowing of the skin or the whites of the eyes)
- signs of lactic acidosis (cold hands or feet, dizziness or light-headedness, slow or irregular heartbeat, weakness or tiredness, unusual muscle pain, trouble breathing, sleepiness or drowsiness, stomach pains, nausea or vomiting)
Warning & Precautions
Pregnancy
Consult your doctorThere is a limited amount of data from the use of ZIMPOMET TABLET in pregnant women. Hence consult your doctor for advice.
Breastfeeding
Consult your doctorThere is a limited amount of data from the use of ZIMPOMET TABLET in breastfeeding women. Hence consult your doctor for advice.
Driving and Using Machines
Use with CautionDo not drive or operate any heavy tools or machines if your ability is affected by the medicine.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking ZIMPOMET TABLET as it may increase the risk of unwanted side effects.
Kidney
ContraindicatedZIMPOMET TABLET is not recommended for use in patients with severe kidney problems.
Liver
Consult your doctorZIMPOMET TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with other liver problems.
Allergy
ContraindicatedDo not take ZIMPOMET TABLET if you are allergic to Metformin or any other ingredients of this medicine.
Lungs
ContraindicatedIt is not recommended for use in patients with severe infection of lungs or respiratory tract.
Heart Disease
ContraindicatedZIMPOMET TABLET is not recommended for use in patients with heart problems (such as acute heart failure or a recent heart attack).
Use In Pediatrics
Consult your doctorZIMPOMET TABLET has not been studied in children. Consult your doctor for advice.
Use In Geriatrics
Use with CautionZIMPOMET TABLET should be used with caution in elderly patients (aged above 65 years).
Others
ZIMPOMET TABLET is not recommended for use if you:
- have severe, uncontrollable diabetes
- have lactic acidosis or ketoacidosis
- are dehydrated
- have any systemic infection
- have shock or problems in blood circulation
- have breathing problems
- are an alcoholic
Before taking ZIMPOMET TABLET, inform your doctor if you:
- are about to have any X-ray or scan
- are about a have a major surgery
- are in fasting
Interactions
A. Drug-Drug interactions:
Before taking ZIMPOMET TABLET, inform your doctor if you are taking any of the following medicines such as:
- Anti-diabetics agents (Ex. teneligliptin, rosiglitazone, pioglitazone, glimepiride)
- Diuretics (Ex. furosemide, hydrochlorothiazide)
- Non-steroidal inflammatory agents (Ex. ibuprofen, celecoxib)
- Antihypertensives (Ex. atenolol, propranolol, captopril, enalapril, ramipril, lisinopril, losartan, valsartan, olmesartan, telmisartan)
- Bronchodilators (Ex. salbutamol, terbutaline)
- Corticosteroids (Ex. hydrocortisone, prednisolone)
- Calcium-channel blockers (Ex. verapamil)
- Antibiotics (Ex. rifampicin)
- H2 blockers (Ex. cimetidine)
- Anti-viral agents (Ex. dolutegravir)
- Anti-anginals (Ex. ranolazine)
- Folic acid inhibitors (Ex. trimethoprim)
- Kinase inhibitors (Ex. vandetanib, crizotinib, olaparib)
- Anti-fungals (Ex. isavuconazole)
Overdosage:
If you or anyone else accidentally takes more ZIMPOMET TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are vomiting, stomach pain with muscle cramps, feeling generally unwell with severe tiredness and difficulty in breathing.
Synopsis
| Drug | : | Metformin |
| Pharmacological Category | : | Biguanides |
| Therapeutic Indication | : | Type II Diabetes mellitus |
| Dosage Forms | : | Tablet |
More Information
FAQs About ZIMPOMET TABLET
Q: What is ZIMPOMET TABLET used for?
A: ZIMPOMET TABLET is used to manage type II diabetes mellitus when diet, exercise and lifestyle changes alone does not result in adequate response.
Q: How and when to take ZIMPOMET TABLET?
A: Take ZIMPOMET TABLET preferably after meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Q: How long should I take ZIMPOMET TABLET?
A: You need to take ZIMPOMET TABLET as long as your doctor or physician prescribes you the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Q: What is the best time to take ZIMPOMET TABLET?
A: ZIMPOMET TABLET must be taken with meals to avoid gastrointestinal side effects.
Q: What to do if I forgot to take a dose of ZIMPOMET TABLET?
A: If you forgot to take a dose of ZIMPOMET TABLET, take it as soon as you remember. However, if it is time for the next dose of ZIMPOMET TABLET, skip the missed dose and take the next one regularly. Do not take a double dose to compensate the missed ones.
Q: What are the most common side effects of taking ZIMPOMET TABLET?
A: The most common side effects of taking ZIMPOMET TABLET are nausea, stomach upset and diarrhea. These side effects can be controlled when ZIMPOMET TABLET is taken along with meals. However, if these side effect bothers you or worsens contact your doctor.
Q: Can I stop taking ZIMPOMET TABLET without consulting your doctor?
A: No. You should not stop taking ZIMPOMET TABLET without consulting your doctor because it may lead to reversal of symptoms. If you feel better after using ZIMPOMET TABLET, consult your doctor for advice.
Q: Will taking a higher dose of ZIMPOMET TABLET be more effective?
A: No, taking a higher dose of ZIMPOMET TABLET will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
Q: What precautions do I need to follow while taking ZIMPOMET TABLET?
A: Before taking ZIMPOMET TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have any severe systemic infections or are severely dehydrated due to excessive vomiting or diarrhea recently. Along with the therapy, follow the diet and lifestyle changes advised by your doctor to achieve better results. Consult your doctor before taking ZIMPOMET TABLET if you are pregnant or breastfeeding.
Q: Can I take medication for high blood pressure along with ZIMPOMET TABLET?
A: It is not advisable to take medicines to control blood pressure while taking ZIMPOMET TABLET without consulting your doctor. Therefore, consult your doctor before taking any antihypertensive such as beta blockers (Ex. atenolol, propranolol) along with ZIMPOMET TABLET as they have known interactions with ZIMPOMET TABLET.
Q: What should I do if I experience low blood sugar after taking ZIMPOMET TABLET?
A: ZIMPOMET TABLET is unlikely to cause low blood sugar unless combined with other anti-diabetic medicine. However, if you experience any signs of low blood sugar levels (such as increased hunger, sweating, shakiness, weakness or an irregular heartbeat), consume a sugary snack or sugar drink immediately. Consult your doctor if the symptom did not improve.
Q: Can ZIMPOMET TABLET be taken with insulin?
A: Co-administration of ZIMPOMET TABLET with insulin is considered risky as they are increased chances of hypoglycemia (decreased blood sugar levels). Consult your doctor before taking it.
Q: Can ZIMPOMET TABLET be used in pregnant women?
A: ZIMPOMET TABLET should be used during pregnancy only if it is considered necessary by the physician. Therefore, consult your doctor for advice.
Q: How to take ZIMPOMET TABLET?
A: You must take ZIMPOMET TABLET as advised by your physician. Try to take this medicine preferably after meals and swallow it with a glass of water. Do not crush or chew the medicine.
Q: How much ZIMPOMET TABLET should I take?
A: ZIMPOMET TABLET should be used only under medical supervision. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body condition and severity of the disease condition.
References
1. KD. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 275.
2. Calette Corcoran; Tibb F. Jacobs. Metformin. StatPearls. NIH. National Library of Medicine. National center for biotechnology information. PMC. PubMed Central. [Revised on May 2022]. [Accessed on 14th October 2022] click here
3. Shuyan Gu, Jihao Shi, Zhiliu Tang, Monika Sawhney, Huimei Hu, Lizheng Shi, Vivian Fonseca, Hengjin Dong. Comparison of Glucose Lowering Effect of Metformin and Acarbose in Type 2 Diabetes Mellitus: A Meta-Analysis. PLOS ONE. May 2015. [Accessed on 14th October 2022] click here
4. Milpharm Limited. Electronic Medicines Compendium (EMC). [Revised in June 2020] [Accessed on 14th October 2022] click here
5. Rx Farma Limited. Electronic Medicines Compendium (EMC). [Revised in September 2019] [Accessed on 14th October 2022] click here
6. Merck Santé S.A.S. U.S. Food & Drug Administration. [Revised in April 2017] [Accessed on 14th October 2022] click here
7. Franco Indian Pharmaceuticals Pvt Ltd. GLYCIPHAGE® GLYCIPHAGE 850® GLYCIPHAGE 250®TABLETS. (ORAL ANTI-HYPERGLYCEMIC AGENT). [Accessed on 14th October 2022] click here
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