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Zidime O 200mg Tablet 6'S

Bacterial Infections
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    Introduction About ZIDIME O 200MG TABLET

    ZIDIME O 200MG TABLET is a combination of Cefpodoxime and Ofloxacin which belongs to the group of medicines called Cephalosporin antibiotics and Fluoroquinolones, respectively. ZIDIME O 200MG TABLET is used to manage mild to moderate bacterial infections such as acute otitis media, pharyngitis and sinusitis in affected individuals.

    ZIDIME O 200MG TABLET is not recommended for use in patients allergic to Cefpodoxime, Ofloxacin and/other cephalosporin antibiotics (such as cephalexin). It is also not recommended for use in patients suffering from epilepsy.

    Before taking ZIDIME O 200MG TABLET, inform your doctor if you have stomach/intestinal disease, blood clotting disorders, diarrhoea, kidney disease and/or liver disease.

    ZIDIME O 200MG TABLET is not recommended for use during pregnancy as it may cause harm to the foetus. It is also not recommended for use in breastfeeding women since it may pass through breast milk.

    ZIDIME O 200MG TABLET is not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged above 65 years) after consulting the doctor.

    The most common side effects of taking ZIDIME O 200MG TABLET are stomach pain, nausea, vomiting, diarrhea, dizziness, headache and/or pain in neck, lower legs. Consult your doctor if any of these symptoms worsens.

    Uses Of ZIDIME O 200MG TABLET

    • Manage mild to moderate bacterial infections such as acute otitis media (middle ear infection), pharyngitis (sore throat) and sinusitis (infection of sinus) in affected individuals

    How ZIDIME O 200MG TABLET Works

    ZIDIME O 200MG TABLET manages bacterial infections, where Cefpodoxime works by managing the formation of the bacterial protective covering which is essential for the survival of the bacteria in the human body and Ofloxacin works by inhibiting DNA gyrase (enzyme responsible for replication, transcription and repair of the DNA) which results in destruction of bacteria thus managing and managing the spread of bacterial infection in affected individuals.

    How to use ZIDIME O 200MG TABLET

    Tablet:

    Take ZIDIME O 200MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

    Dispersible Tablet:

    Take ZIDIME O 200MG TABLET as advised by your physician. Disperse the medicine in the specified quantity of water as mentioned in the label. Do not crush or chew the medicine. Consume the medicine immediately after reconstitution. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

    Side Effects Of ZIDIME O 200MG TABLET

    Common

    • stomach pain, nausea, vomiting, diarrhea
    • dizziness
    • headache
    • pain in neck, lower legs

    Rare

    Stop taking ZIDIME O 200MG TABLET and contact your doctor immediately if you experience any of the following side effects:

    • signs of serious allergic reactions such as rashes, difficulty in breathing

    How To Manage Side Effects

    Nausea and vomiting:

    Take ZIDIME O 200MG TABLET with or just after a meal. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Inform your doctor if the condition worsens.

    Diarrhea:

    Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult and inform your doctor if the symptom worsens.

    Dizziness:

    Try to rest and get enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Limit consumption of alcohol, as it can aggravate dizziness. Consult and inform your doctor if the symptom worsens.

    Headache:

    If ZIDIME O 200MG TABLET causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking ZIDIME O 200MG TABLET. If it lasts more than a week or severe, inform your doctor.

    Warning & Precautions

    Pregnancy

    ZIDIME O 200MG TABLET is not recommended for use during pregnancy since the medicine may harm the foetus. Consult your doctor before taking ZIDIME O 200MG TABLET.

    Breastfeeding

    ZIDIME O 200MG TABLET is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking the medicine.

    Driving and Using Machines

    Do not drive or operate any machines if you experience sleepiness, dizziness and/or blurred vision after taking ZIDIME O 200MG TABLET.

    Alcohol

    Avoid alcohol consumption of alcohol while taking ZIDIME O 200MG TABLET since it may cause drowsiness.

    Kidney

    ZIDIME O 200MG TABLET should be used caution in patients with kidney disease. Consult your doctor before taking ZIDIME O 200MG TABLET.

    Liver

    ZIDIME O 200MG TABLET should be used with caution in patients with liver disease. Consult your doctor before taking ZIDIME O 200MG TABLET.

    Allergy

    Do not take ZIDIME O 200MG TABLET if you are allergic to Cefpodoxime, Ofloxacin, other cephalosporin antibiotics (such as cephalexin) and/or any other ingredients of this medicine.

    Others

    ZIDIME O 200MG TABLET is not recommended for use if you:

    • have epilepsy

    Before taking ZIDIME O 200MG TABLET, inform your doctor if you:

    • suffer from viral infections such as common cold flu
    • have stomach/intestinal disease
    • suffer from blood clotting disorders
    • have diarrhoea

    Use in Paediatrics:

    ZIDIME O 200MG TABLET is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before taking ZIDIME O 200MG TABLET.

    Use in Geriatrics:

    ZIDIME O 200MG TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking the medicine.

    Interactions

    A. Drug-Drug interactions:

    Inform your doctor about all the medicines you use including prescription, non-prescription and herbal medicines.

    B. Drug-Food interaction:

    Avoid consuming milk and dairy products as it may alter the effect the medicine. Consult your doctor before taking ZIDIME O 200MG TABLET.

    Overdosage:

    If you or anyone else accidentally take too much of ZIDIME O 200MG TABLET, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.

    Synopsis

    Drug :   Cefpodoxime, Ofloxacin
    Pharmacological Category :   Cephalosporin antibiotic, Fluoroquinolone
    Therapeutic Indication :   Bacterial infections
    Dosage Forms :   Tablet

    More Information

    • Keep ZIDIME O 200MG TABLET out of reach of children
    • Store ZIDIME O 200MG TABLET at a cool and dry place

    FAQs About ZIDIME O 200MG TABLET

    What is ZIDIME O 200MG TABLET used for?

    ZIDIME O 200MG TABLET is a combination of Cefpodoxime and Ofloxacin which belongs to the group of medicines called Cephalosporin antibiotics and Flouroquinolones. It is generally used to manage mild to moderate bacterial infections such as acute otitis media, pharyngitis and sinusitis in affected individuals.

    What are the side effects of ZIDIME O 200MG TABLET?

    The most common side effects of taking ZIDIME O 200MG TABLET are stomach pain, nausea, vomiting, diarrhea, dizziness, headache and/or pain in neck, lower legs. Consult your doctor if any of these symptoms worsens.

    How ZIDIME O 200MG TABLET works?

    ZIDIME O 200MG TABLET manages bacterial infections, where Cefpodoxime works by managing the formation of the bacterial protective covering which is essential for the survival of the bacteria in the human body and Ofloxacin works by inhibiting DNA gyrase (enzyme responsible for replication, transcription and repair of the DNA) which results in destruction of bacteria thus managing and managing the spread of bacterial infection in affected individuals.

    How to take ZIDIME O 200MG TABLET?

    Tablet:

    Take ZIDIME O 200MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

    Dispersible Tablet:

    Take ZIDIME O 200MG TABLET as advised by your physician. Disperse the medicine in the specified quantity of water as mentioned in the label. Do not crush or chew the medicine. Consume the medicine immediately after reconstitution. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

    Can ZIDIME O 200MG TABLET be used in children?

    No, ZIDIME O 200MG TABLET is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before taking ZIDIME O 200MG TABLET.

    References

    1. K.D. Tripathi. Beta-lactam Antibiotics and Sulphonamides, Cotrimoxazole & Quinolones. Essentials of medical pharmacology. Seventh edition. 2013. Page- 728, 713.

    2. M T Borin, J J Ferry, K K Forbes, G S Hughes. Pharmacokinetics of cefpodoxime proxetil in healthy young and elderly volunteers. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. [Revised in July 1994] [Accessed on 11th June 2022] https://pubmed.ncbi.nlm.nih.gov/7929873/

    3. P Veyssier, J B Fourtillan, J Modai, W Couet, M A Lefebvre, J P Darchis, M Vincent Du Laurier, A Bryskier. Pharmacokinetics of ofloxacin in the elderly (65-85 years) with normal renal function after a single oral dose of 200 mg. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. [Revised in June 1986] [Accessed on 11th June 2022] https://pubmed.ncbi.nlm.nih.gov/3534750/

    4. Saintroy Lifescience. Olipod-OF 100. [Accessed on 11th June 2022] https://m.saintroylifescience.com/cefpodoxime-and-ofloxacin-tablets-6873585.html

    5. Integrated Laboratories Pvt Ltd. INTEDPOD - OF. [Accessed on 11th June 2022] https://integratedlaboratories.in/cefpodoxime-proxetil-ofloxacin-200-mg-tablets-intepod-of/

    6. Vibcare Pharma Pvt. Ltd. ODOXICEF O / CEFDOFEC O. [Accessed on 11th June 2022] https://vibcare.co.in/cefpodoxime-ofloxacin/

    7. Alpha Drugs. SYFEDOX-O. [Accessed on 11th June 2022] https://www.alphadrug.in/product/syfedox-o/

    8. Zeelab Pharmacy. Zedoxy-O 200. [Accessed on 11th June 2022] https://zeelabpharmacy.com/product/zedoxy-o-200

    9. Smotec Pharmaceuticals. SMOPOD-OF. [Accessed on 11th June 2022] https://www.smotecpharma.com/smopod-of

    10. StayHappi Pharmacy. Cefpodoxime Proxetil & Ofloxacin Tablets. [Accessed on 11th June 2022] https://www.stayhappi.com/stayhappi-generics/cefpodoxime-proxetil-200-mg-ofloxacin-200-mg-tablet-10s-8665

    11. Wellona Pharma. CEFPOWELL-OF. [Accessed on 11th June 2022] https://wellonapharma.com/product/finished/cefpodoxime-and-ofloxacin-tablets

    12. Actiza Pharmaceutical Private Limited. Cefpodoxime and ofloxacin tablets. [Accessed on 11th June 2022] https://www.actizapharma.com/products/cefpodoxime-proxetil-ofloxacin/

    13. Alpic Remedies Ltd. Cipalp-O. [Accessed on 11th June 2022] https://www.alpicremediesltd.com/cefpodoxime-proxetil-200-mg-ofloxacin-3348739.html

    Useful Diagnostic Tests

    • Bacterial Culture test
    • Complete blood count

    Author Details

    Written By Dr. K .AZEEM HUSSAIN - B.D.S
    Reviewed For Accuracy By Dr. Salem Gill - MBBS
    Last updated on 23 Nov 2022 | 06:22 PM(IST)
    Lab updated