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Introduction About ZERODOL P TABLET
Zerodol P Tablet contains Aceclofenac (100 mg) and Paracetamol (325 mg), a dual-action blend crafted to ease joint stiffness, muscle aches, dental discomfort, and postoperative soreness. This combination is known for supporting better mobility and enhancing overall comfort. Zerodol P Tablet is commonly used for reducing pain and inflammation linked to rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It also offers reliable relief during episodes of back pain, muscle strain, toothache, and discomfort in the ear or throat, helping users experience faster and more effective comfort.
Zerodol P Tablet can be taken with or without food, depending on what feels comfortable for you. For the best results, use it consistently as recommended by your healthcare professional. Your doctor may adjust the dosage or timing based on your discomfort level and overall requirement. Avoid taking more than the suggested amount or using it for longer than advised.
Common side effects of this medicine include nausea, vomiting, stomach discomfort, heartburn, indigestion, diarrhoea, dizziness, headache, or a skin rash. Inform your doctor if any of these effects become bothersome or persist over time. Your doctor may guide you with suitable options such as adjusting the dosage or suggesting an alternative if you experience ongoing discomfort.
Zerodol P Tablet may not be suitable for everyone. Before using it, inform your doctor if you have any heart-related, kidney-related, or liver-related concerns, or if you have a history of stomach ulcers. Make sure to share details about any other medicines or supplements you are taking so your doctor can ensure they are compatible. Pregnant and breastfeeding women should seek medical guidance before starting Zerodol P Tablet.
Key Composition
- Aceclofenac (100 mg): Supports reduction of inflammation, swelling, and joint-related discomfort.
- Paracetamol (325 mg): Helps ease pain sensations and enhances the overall comfort effect of the combination.
Uses Of ZERODOL P TABLET
- Supports relief from joint pain and joint stiffness
- Helps ease muscle pain and body aches
- Useful for dental pain and post-dental discomfort
- Offers comfort during postoperative pain episodes
- Commonly used for rheumatoid arthritis related discomfort
- Helps reduce stiffness in ankylosing spondylitis
- Provides support for osteoarthritis pain
- Effective for back pain and muscular strain
- Helps with toothache discomfort
- Supports relief from ear and throat pain
Benefits of ZERODOL P TABLET
- Strong Dual-Action Pain Relief: Helps ease mild to severe discomfort linked to joint issues, muscle strain, back pain, dental pain, and injury related soreness.
- Supports Reduction of Inflammation: Assists in lowering swelling and stiffness commonly associated with arthritis and other inflammatory conditions.
- Enhances Mobility & Flexibility: Helps improve daily movement by reducing joint-related discomfort and stiffness.
- Useful for Arthritis-Related Discomfort: Provides dependable comfort for individuals experiencing pain linked to rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
- Offers Relief from Acute Pain Episodes: Helps manage sudden pain such as headaches, postoperative soreness, or musculoskeletal strain.
- Comfort for Ear, Throat & Tooth Pain: Supports relief from discomfort caused by earache, sore throat, and toothache.
- Fast-Acting Formula: Begins working relatively quickly, helping users experience noticeable comfort within a short duration.
- Ideal for Short-Term Pain Episodes: Suitable for reducing pain intensity during daily activities, travel, work, or recovery periods.
- Widely Trusted Combination: Aceclofenac + Paracetamol is well-known for its balanced, effective approach to pain and inflammation control.
- Can Fit into Routine Pain Management: May be used alongside other doctor-recommended medicines when guidance is provided by a healthcare professional.
How ZERODOL P TABLET Works
How Does Zerodol P Tablet Work?
Zerodol P Tablet works by targeting the pathways in the body responsible for pain signals and inflammation. Its dual-action formula helps reduce discomfort, ease swelling, and support smoother movement during daily activities.
Mechanism of Action: Aceclofenac and Paracetamol
Aceclofenac helps minimize inflammation by blocking chemical messengers responsible for pain and swelling, while Paracetamol enhances overall pain relief by influencing pain-regulating centers in the brain. Together, they offer stronger and more balanced comfort.
What Happens in the Body After Taking Zerodol P?
After consumption, the tablet is absorbed into the bloodstream, where its active ingredients begin working on pain pathways and inflammatory responses. This results in reduced discomfort, improved mobility, and relief from stiffness within a short duration.
How to use ZERODOL P TABLET
How to Take Zerodol P Tablet
- Zerodol P Tablet can be taken with or without food, based on personal comfort.
- Swallow the tablet whole with water, following the guidance provided by your healthcare professional to achieve effective pain and inflammation relief.
Recommended Dosage and Timing
- Take Zerodol P exactly as advised by your doctor.
- Dosage and intervals may be adjusted according to your pain intensity, joint stiffness, or muscle discomfort to ensure optimal results without overuse.
Safe Administration Tips
- Always follow the prescribed schedule and avoid self-adjusting the dose.
- Take the tablet with adequate water, avoid prolonged use without consultation, and monitor for any unusual discomfort or reactions.
Who Should Adjust Their Dose?
- Individuals with kidney, liver, or heart concerns, stomach ulcers, or those taking multiple medications should consult their doctor before adjusting the dose.
- Pregnant and breastfeeding women should also seek medical guidance before use.
What if I forgot to take ZERODOL P TABLET
- If you miss a dose, take it as soon as you remember. Avoid doubling up on the next dose to compensate.
- Taking more than the recommended amount may increase the risk of side effects.
Side Effects Of ZERODOL P TABLET
Common:
- Nausea
- Vomiting
- Stomach discomfort
- Heartburn
- Indigestion
- Diarrhoea
- Dizziness
- Headache
- Skin rash
When to consult your doctor?
- Severe allergic reactions symptoms such as rash, itching, swelling of the face, lips, tongue, or throat, causing difficulty in breathing or swallowing.
- Intense stomach pain or bleeding symptoms such as vomiting blood, black or tarry stools, or persistent abdominal discomfort.
- Heart related symptoms such as chest pain, irregular heartbeat, unexplained shortness of breath.
- Liver issues symptoms such as yellowing of the skin or eyes (jaundice), dark urine, or persistent fatigue.
- Kidney related problems symptoms such as reduced urination, swelling in the legs or ankles, or unusual fluid retention.
- Neurological symptoms such as severe dizziness, fainting, confusion, or sudden headaches.
- Severe skin reactions symptoms such as blistering, peeling, or widespread rashes.
How To Manage Side Effects
Dizziness Or Drowsiness
- Sit or Lie Down: If you feel dizzy, sit down, or lie down immediately to reduce falling. Keep your head still and close your eyes if needed.
- Hydrate: Dehydration can cause dizziness, so drink water or electrolyte-replenishing drinks like sports drinks.
- Avoid Sudden Movements: When standing or sitting, do so slowly to avoid triggering dizziness. Take your time when getting up.
- Eat Small, Regular Meals: Low blood sugar can cause dizziness, so eat small meals throughout the day and avoid skipping meals.
- Fresh Air: Sometimes dizziness can be alleviated by taking slow, deep breaths in a well-ventilated area.
Headache
- Stay Hydrated: Drink plenty of water throughout the day to help ease headache symptoms.
- Rest in a Quiet Environment: Minimize noise and bright lights by resting in a calm, dark room.
- Use Over-the-Counter Pain Relief: Consult your doctor about using mild pain relievers like acetaminophen to alleviate headaches.
- Avoid Stressful Activities: Limit activities that increase stress or physical exertion when experiencing headaches.
- Seek Medical Advice: Contact your healthcare provider if headaches become severe, persistent, or are accompanied by other symptoms.
Nausea And Vomiting
- Stay Hydrated: Sip fluids slowly, such as water, ginger tea, or clear soups to support hydration and reduce discomfort.
- Eat Small, Bland Meals: Choose light foods like crackers, toast, or plain rice to minimize stomach irritation.
- Avoid Strong Odors and Spicy Foods: These can worsen feelings of nausea and should be limited during symptoms.
- Rest and Relaxation: Rest in a comfortable position and avoid sudden movements to calm the digestive system.
- Seek Medical Advice: Consult a healthcare provider promptly if nausea is severe, persistent, or accompanied by vomiting.
Warning & Precautions
Pregnancy
Consult your doctorZERODOL P TABLET should be used in pregnant women only after consulting your doctor or healthcare professional to ensure safety for both mother and baby.
Breastfeeding
Consult your doctorZERODOL P TABLET should be used in breastfeeding women only after consulting your doctor to avoid potential risk to the infant.
Driving and Using Machines
Use with CautionDo not take ZERODOL P TABLET while driving or operating machinery, as it may cause blurred vision, dizziness, or drowsiness, affecting alertness and reaction time.
Kidney
Consult your doctorZERODOL P TABLET is not recommended for patients with severe kidney problems. It should be used with caution in individuals with mild renal impairment. Consult your doctor before taking it.
Liver
ContraindicatedZERODOL P TABLET is not recommended in patients with severely impaired liver function (hepatic dysfunction). Consult your doctor before taking it.
Allergy
ContraindicatedDo not take ZERODOL P TABLET if you are allergic (hypersensitive) to Aceclofenac or Paracetamol, or any other ingredient in this medicine.
Lungs
ContraindicatedZERODOL P TABLET is not recommended for patients with lung conditions such as asthma or bronchospasm. Consult your doctor before taking it.
Heart Disease
ContraindicatedZERODOL P TABLET is not recommended in patients with severe heart problems, including heart failure. Consult your doctor before taking it.
Use In Pediatrics
Consult your doctorZERODOL P TABLET should be used in children aged above 6 years only after consulting a doctor. It is not suitable for children below 6 years due to lack of safety data. Consult your child’s doctor for advice.
Use In Geriatrics
Use with CautionZERODOL P TABLET should be used with caution in elderly patients (65 years and above). Consult your doctor or healthcare professional before starting this medicine.
Other Warnings for ZERODOL P TABLET
Before taking ZERODOL P TABLET, inform your doctor if you:
- Have a history of gastrointestinal ulceration (stomach ulcer)
- Have inflammatory bowel disease such as ulcerative colitis or Crohn’s disease
- Have bleeding diathesis (increased susceptibility to bleeding or bruising)
- Have haematological abnormalities
Drug - Drug interaction
Before taking ZERODOL P TABLET, inform your doctor if you are taking any of the following medicine:
Blood Thinners (e.g., Warfarin, Aspirin)
- Interaction: Combining Zerodol P Tablet with blood thinners may increase the risk of bleeding.
- Effects: Symptoms may include unusual bruising, bleeding gums, blood in stools, or urine.
- Management: Inform your doctor immediately if you notice any signs of bleeding. Your doctor may adjust your dosage or monitor you closely to ensure safety.
Other NSAIDs (e.g., Ibuprofen, Naproxen)
- Interaction: Using Zerodol P Tablet with other NSAIDs can heighten the risk of gastrointestinal irritation, ulcers, or bleeding.
- Effects: Stomach pain, heartburn, nausea, vomiting, or dark/tarry stools may occur.
- Management: Avoid taking multiple NSAIDs simultaneously unless directed by your doctor.
Corticosteroids (e.g., Prednisone)
- Interaction: Concurrent use may increase the chance of stomach irritation and ulcer formation.
- Effects: Abdominal pain, indigestion, or internal bleeding.
- Management: Your doctor may recommend stomach-protective medication or closer monitoring.
ACE Inhibitors / ARBs (e.g., Enalapril, Losartan)
- Interaction: May reduce the effectiveness of these medications and increase risk of kidney issues.
- Effects: Swelling, fatigue, decreased urine output, or elevated blood pressure.
- Management: Regular monitoring of kidney function and blood pressure is advised.
Diuretics (e.g., Furosemide, Hydrochlorothiazide)
- Interaction: May reduce the effectiveness of diuretics and increase risk of kidney problems.
- Effects: Fluid retention, swelling, or changes in urine output.
- Management: Doctor may adjust dosages or recommend regular kidney function tests.
Lithium or Methotrexate
- Interaction: Zerodol P Tablet may increase blood levels of these medications, raising the risk of toxicity.
- Effects: Confusion, nausea, vomiting, tremors, or unusual fatigue.
- Management: Your doctor may monitor blood levels closely and adjust the dose accordingly.
Antibiotics (e.g., Ciprofloxacin, Amoxicillin)
- Interaction: Concurrent use may slightly affect the absorption or effectiveness of certain antibiotics.
- Effects: Reduced antibiotic efficacy or slower recovery from infections.
- Management: Take antibiotics as prescribed and inform your doctor if infection symptoms persist or worsen.
Anti-Diabetic Drugs (e.g., Metformin, Glibenclamide, Insulin)
- Interaction: Zerodol P Tablet may influence blood sugar levels when taken with anti-diabetic medications.
- Effects: Possible fluctuations in blood glucose, including high or low sugar episodes.
- Management: Regularly monitor blood sugar levels. Your doctor may adjust the diabetes medication dosage accordingly.
Synopsis
| Drug | : | Aceclofenac and Paracetamol |
| Pharmacological Category | : | Non-steroidal Anti-inflammatory drugs |
| Therapeutic Indication | : | Pain Relief |
| Dosage Forms | : | Tablet, Oral suspension, Suspension, Syrup |
More Information
01.Why Zerodol P Tablet is a Better Choice for Fast and Effective Pain Relief Compared to Other Painkillers?
1. Dual Mechanism for Enhanced Pain Relief
Unlike single-action painkillers, Zerodol P targets pain in two ways:
- Aceclofenac reduces inflammation at the source.
- Paracetamol blocks pain signals in the brain for quick relief.
This synergistic effect provides faster and more comprehensive pain relief compared to standard NSAIDs or paracetamol alone.
2. Fast-Acting & Long-Lasting
- Onset of action: 10–30 minutes
- Duration: 4–6 hours
This makes Zerodol P ideal for both acute pain and ongoing inflammatory conditions.
3. Better Tolerability for the Stomach
While NSAIDs can irritate the stomach, Zerodol P is generally well-tolerated, thanks to the inclusion of paracetamol. It reduces gastrointestinal discomfort compared to high-dose NSAIDs.
4. Clinically Proven Effectiveness
Studies have shown that Zerodol P is as effective, or even superior, to some stronger NSAIDs like ketorolac for post-operative and musculoskeletal pain.
5. Cost-Effective Solution
Because of its dual-action formula, fewer doses or additional painkillers are needed, making it economical for short-term pain management.
Why Zerodol P Is a Better Choice?
|
Advantage |
Benefit |
|
Dual action (NSAID + Analgesic) |
Reduces inflammation and pain effectively |
|
Fast onset |
Relief in 10–30 minutes |
|
Reasonable duration |
Covers intermittent pain for 4–6 hours |
|
Lower GI irritation than strong NSAIDs |
Safer for stomach when taken with food |
|
Clinically proven |
Comparable or better than other painkillers |
|
Cost-effective |
Reduces the need for additional medications |
Conclusion
Zerodol P Tablet is a fast, effective, and reliable choice for managing pain caused by inflammation, musculoskeletal issues, and daily aches. Its dual-action formula ensures quick relief while also tackling the underlying inflammation making it a preferred option over standard painkillers.
02. How Can Diet, Exercise, and Lifestyle Changes Support Joint Health Alongside Zerodol P Tablet?
|
Category |
Tip/Strategy |
Benefits |
How It Complements Zerodol P |
|
Diet & Nutrition |
Include anti-inflammatory foods: fatty fish (salmon, mackerel), nuts, olive oil |
Reduces systemic inflammation, may decrease joint stiffness |
Supports the anti-inflammatory effect of aceclofenac in Zerodol P |
|
Eat calcium & vitamin D-rich foods: milk, yogurt, fortified cereals |
Strengthens bones and joints |
Helps maintain skeletal support alongside pain management |
|
|
Incorporate fruits & vegetables rich in antioxidants: berries, spinach, kale |
Protects joint cartilage from oxidative stress |
Enhances overall joint health and recovery |
|
|
Limit processed foods, sugar, and trans fats |
Reduces inflammation and joint swelling |
Works synergistically with Zerodol P for faster relief |
|
|
Exercise & Physical Activity |
Perform low-impact exercises: swimming, cycling, walking |
Improves joint mobility and muscle support |
Reduces stiffness, allowing Zerodol P to act more effectively |
|
Strength training for muscles around joints |
Enhances stability and prevents injury |
Supports pain relief and prevents recurrence of strain |
|
|
Include stretching & flexibility routines: yoga, Pilates |
Maintains range of motion and prevents stiffness |
Complements the pain-relieving effects of Zerodol P |
|
|
Lifestyle Modifications |
Maintain healthy body weight |
Reduces stress on weight-bearing joints (knees, hips) |
Minimizes the load on inflamed joints for better pain control |
|
Apply hot/cold therapy as needed |
Hot compress relaxes muscles; cold packs reduce swelling |
Can provide immediate comfort along with Zerodol P |
|
|
Ensure adequate rest & sleep |
Promotes tissue repair and reduces fatigue |
Improves recovery from pain episodes |
|
|
Avoid repetitive strain activities |
Prevents overuse injuries |
Reduces the need for frequent painkiller doses |
|
|
Hydration & Supplements |
Drink plenty of water |
Keeps joints lubricated and supports nutrient transport |
Helps maintain joint health while Zerodol P manages pain |
|
Consider joint-friendly supplements (Omega-3, glucosamine, chondroitin) with doctor advice |
Supports cartilage health and reduces inflammation |
Works in tandem with Zerodol P for long-term joint support |
FAQs About ZERODOL P TABLET
Q: What is Zerodol P Tablet used for?
A: Zerodol P Tablet is used to relieve pain and reduce inflammation in conditions such as arthritis (osteoarthritis, rheumatoid arthritis, ankylosing spondylitis), muscle and joint pain, backache, headache, toothache, and post-injury or post-surgery pain.
Q: How does Zerodol P Tablet work?
A: Zerodol P combines Aceclofenac (an NSAID) and Paracetamol. Aceclofenac reduces inflammation and swelling, while Paracetamol blocks pain signals in the brain, providing fast and effective pain relief.
Q: How quickly does Zerodol P Tablet provide pain relief?
A: Zerodol P Tablet typically starts working within 10–30 minutes, with effects lasting 4–6 hours, making it suitable for managing acute or intermittent pain.
Q: Can Zerodol P Tablet be taken for headaches and body pain?
A: Yes. Zerodol P is effective for mild to moderate pain such as headaches, body aches, and musculoskeletal pain, while also reducing inflammation associated with conditions like arthritis or injury.
Q: What are the common side effects of Zerodol P Tablet?
A: Common side effects may include nausea, stomach discomfort, dizziness, drowsiness, or mild heartburn. Rarely, it may cause gastrointestinal bleeding, liver or kidney issues.
Q: How should Zerodol P Tablet be taken?
A: It is recommended to take Zerodol P Tablet with food or after meals to minimize stomach irritation, and always as prescribed by a doctor. Avoid taking multiple paracetamol-containing medications simultaneously.
Q: Is Zerodol P Tablet safe for long-term use?
A: Zerodol P is generally used for short-term pain relief. Long-term use should be monitored by a doctor due to potential risks to the stomach, liver, kidneys, and cardiovascular system.
Q: Can Zerodol P Tablet be taken with other medications?
A: Zerodol P may interact with certain medications, such as blood thinners, other NSAIDs, or liver-acting drugs. Always consult a doctor or pharmacist before combining medications.
Q: Can Zerodol P Tablet be taken during pregnancy or breastfeeding?
A: Zerodol P is not recommended during late pregnancy and should only be used during pregnancy or breastfeeding under strict medical supervision.
Q: How does Zerodol P Tablet compare to other painkillers?
A: Unlike single-action painkillers, Zerodol P provides dual-action relief by reducing inflammation (Aceclofenac) and quickly controlling pain (Paracetamol), often offering faster and more comprehensive relief than standard NSAIDs or paracetamol alone.
References
1. KD Tripathi. Nonsteroidal Anti-inflammatory Drugs and Antipyretic-Analgesics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 204, 206.
2. Anil Pareek, Nitin Chandurkar, V D Sharma, Mohan Desai, Seema Kini, Girish Bartakke. A randomized, multicentric, comparative evaluation of aceclofenac-paracetamol combination with aceclofenac alone in Indian patients with osteoarthritis flare-up. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. April 2009. [Accessed on 19th November 2025] ![]()
3. Taj Life Sciences. Aceclofenac and Paracetamol 100/325mg. [Accessed on 19th November 2025] 
4. Taj Life Sciences. Aceclofenac and Paracetamol 100/500mg. [Accessed on 19th November 2025] 
5. Aceclofenac and Paracetamol Tablets. Summary of Product Characteristics. [Accessed on 19th November 2025] 
6. Lifecare Neuro Products. Ano-Plus. Aceclofenac and Paracetamol Tablet. [Accessed on 19th November 2025] 
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