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Introduction About ZEBLONG 16 TABLET
ZEBLONG 16 TABLET contains Azelnidipine which belongs to the group of medicines called Antihypertensive agents. It is indicated for the management of stage-I and stage-II hypertension. Hypertension is a condition in which force of the blood is consistently high against the walls of the arteries which can increase the risk of heart disease, kidney disease or stroke.
Stage I hypertension has systolic pressure ranging from 130 to 139 mm Hg or a diastolic pressure ranging from 80 to 89 mm Hg. Stage II hypertension has systolic pressure ranging from 140 mm Hg or higher or a diastolic pressure ranging from 90 mm Hg or higher.
Along management with ZEBLONG 16 TABLET, your doctor might advise you to follow certain lifestyle changes such as eating healthy diet, taking adequate sleep, weight and stress management and avoid smoking or drinking alcohol.
Before taking ZEBLONG 16 TABLET inform your doctor if you have liver or kidney diseases or any other medical conditions. Your doctor might ask you to take some blood tests before initiating the management with ZEBLONG 16 TABLET to understand the existing condition and for proper use of this medicine.
ZEBLONG 16 TABLET is not recommended for use in pregnant women or women who has a possibility to conceive, and breast-feeding women. ZEBLONG 16 TABLET should be used with caution in elderly patients.
Avoid consumption of grapefruit juice while taking ZEBLONG 16 TABLET as it may increase the risk of low blood pressure. The most common side effects of taking ZEBLONG 16 TABLET are dizziness, light-headedness, nausea, constipation, fatigue and stomach pain. Consult your doctor if any of the side effect worsens.
Uses Of ZEBLONG 16 TABLET
- Management of stage-I and stage-II hypertension
How ZEBLONG 16 TABLET Works
ZEBLONG 16 TABLET works by inhibiting the movement of calcium ions into both vascular smooth muscle and cardiac muscle resulting in lower blood pressure by relaxing the blood vessels and improving the flow of blood to the heart muscles.
How to use ZEBLONG 16 TABLET
Take ZEBLONG 16 TABLET as advised by your doctor. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age and general health condition. Do not stop taking ZEBLONG 16 TABLET unless your doctor advises you to stop.
Side Effects Of ZEBLONG 16 TABLET
Common
- rash, itching
- headache, heavy headed feeling, unsteady
- dizziness, light-headedness, drowsiness
- gastric distress, nausea, constipation, stomach pain, diarrhoea
- palpitation
- sensation of warmth, skin flushing on face portion
- fatigue, abnormal sensation
- frequent urination
- swelling
- numbness
Stop taking ZEBLONG 16 TABLET and inform your doctor immediately if you experience any of the following side effects:
- jaundice and liver function failure (signs include pain in upper abdomen, abdominal swelling, tremors, disorientation, nausea, vomiting)
- cardiac arrest (signs include chest pain, palpitations, irregular heartbeat and shortness of breath)
- sinus block (heart rhythm disorder)
- slowed heart rate (bradycardia)
How To Manage Side Effects
Constipation
Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly. Consult your doctor if the symptom does not improve.
Diarrhea
Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Try to avoid taking any medicine on your own to manage diarrhea and consult your doctor if the symptom gets worse.
Dizziness Or Drowsiness
Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol and drugs. Consult your doctor if the symptom gets worse.
Headache
Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.
Nausea And Vomiting
Stick to simple meals while taking this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve.
Stomach Pain
Try to rest and relax. Try to have smaller and frequent meals and have them slowly. Keep a heat pad on your stomach. Ask for your doctor’s advice if stomach pain doesn’t improve.
Warning & Precautions
Pregnancy
ContraindicatedZEBLONG 16 TABLET is not recommended for use in pregnant women or women who has a possibility to conceive because it may affect the developing baby resulting in death of the fetus, reduced weight of the born child or extension in pregnancy and delivery period. Consult your doctor before taking ZEBLONG 16 TABLET.
Breastfeeding
ContraindicatedZEBLONG 16 TABLET is not recommended for use in breastfeeding women as it passes through the breast milk. Consult your doctor before taking ZEBLONG 16 TABLET
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel giddy (whirling or spinning sensation) after taking ZEBLONG 16 TABLET.
Kidney
Use with CautionZEBLONG 16 TABLET should be taken with caution in patients with kidney problems. Consult your doctor before taking it.
Liver
Use with CautionZEBLONG 16 TABLET should be taken with caution in patients with liver problems. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take ZEBLONG 16 TABLET if you are allergic to Azelnidipine or any other ingredients of this medicine.
Use In Pediatrics
Consult your doctorSafety of ZEBLONG 16 TABLET in babies with low birth weight, newborn babies, lactating babies, infants or small children is not yet established. Consult your child’s doctor for advice.
Use In Geriatrics
Use with CautionZEBLONG 16 TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking ZEBLONG 16 TABLET.
Interactions
A. Drug-Drug Interactions:
Before taking ZEBLONG 16 TABLET, inform your doctor if you are taking any of the following medicines:
- medicines used to manage fungal infections (Ex. itraconazole, miconazole)
- medicines used to manage HIV infections (Ex. ritonavir, saquinavir, indinavir, delavirdine)
- cimetidine (used to manage stomach problems)
- imatinib (used to manage cancer)
- medicines used to manage bacterial infections (Ex. erythromycin, clarithromycin, rifampicin)
- cyclosporine (used to suppress the immune system to stop organ rejection after transplant)
- medicines used to manage anxiety, insomnia (Ex. diazepam, midazolam, triazolam, tandospirone)
- phenytoin, phenobarbital (used to manage seizures)
- medicines used to inhibit the occurence pregnancy (Ex. estradiol, norethindrone)
- digoxin (used to manage heart diseases)
- simvastatin (used to control high cholesterol levels)
B. Drug-Food Interactions:
Avoid consumption of grapefruit juice while taking ZEBLONG 16 TABLET as it may increase the risk of low blood pressure.
Overdosage:
If you or anyone else accidentally take too much of ZEBLONG 16 TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of ZEBLONG 16 TABLET are abnormally low blood pressure and reflex tachycardia (rapid heartbeat).
Synopsis
| Drug | : | Azelnidipine |
| Pharmacological Category | : | Calcium channel blocker |
| Therapeutic Indication | : | Stage-I and Stage-II hypertension |
| Dosage Forms | : | Tablet |
More Information
Storage
- Keep ZEBLONG 16 TABLET out of reach of children
- Store ZEBLONG 16 TABLET at room temperature
FAQs About ZEBLONG 16 TABLET
Q: What is [GBNKEYORD] and why is it prescribed?
A: ZEBLONG 16 TABLET contains Azelnidipine which belongs to the group of medicines called Antihypertensive agents. It is indicated for the management of stage-I and stage-II hypertension. Stage I hypertension has systolic pressure ranging from 130 to 139 mm Hg or a diastolic pressure ranging from 80 to 89 mm Hg. Stage II hypertension has systolic pressure ranging from 140 mm Hg or higher or a diastolic pressure ranging from 90 mm Hg or higher.
Q: Can ZEBLONG 16 TABLET affect my ability to drive?
A: ZEBLONG 16 TABLET has an antihypertensive effect (low blood pressure may result in dizziness or giddiness). Do not drive or operate any machines if you feel giddy (whirling or spinning sensation) after taking ZEBLONG 16 TABLET. You can resume with your activities once you feel normal again. Consult your doctor for advice.
Q: Is ZEBLONG 16 TABLET safe to use in pregnant women?
A: ZEBLONG 16 TABLET is not recommended for use in pregnant women or women who has a possibility to conceive because it may affect the developing baby resulting in death of the fetus, reduced weight of the born child or extension in pregnancy and delivery period. Consult your doctor before taking it.
Q: What if I forget to take a dose of ZEBLONG 16 TABLET?
A: If you forget to take a dose of ZEBLONG 16 TABLET, take it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not take ZEBLONG 16 TABLET twice to make up for the forgotten dose.
Q: Is ZEBLONG 16 TABLET safe to use in patients with kidney problems?
A: ZEBLONG 16 TABLET should be taken with caution in patients with kidney problems. Your doctor may adjust the dose based on functioning of the kidney. Consult your doctor before taking ZEBLONG 16 TABLET.
References
1. Sean C Sweetman. Cardiovascular Drugs. Martindale-The Complete Drug Reference. Thirty Sixth Edition. 2009. Page-1222.
2. Keri Wellington, Lesley J Scott. Azelnidipine. NIH. National Library of Medicine, National center for biotechnology information. Pubmed.gov. 2003. [Accessed on 21st November 2023] https://pubmed.ncbi.nlm.nih.gov/14636080/
3. Bi-Lian Chen, Yin-Zhuang Zhang, Jian-Quan Luo, and Wei Zhang. Clinical use of azelnidipine in the treatment of hypertension in Chinese patients. NIH. National Library of Medicine, National center for biotechnology information. Pubmed Central. February 2015. [Accessed on 21st November 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348133/
4. Torrent Pharmaceuticals Ltd. Uniaz (Azelnidipine). [Revised in April 2020] [Accessed on 21st November 2023] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2900.pdf
Useful Diagnostic Tests
- Cardia Risk Profile
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