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Introduction About XYLOMIST P NASAL DROPS
XYLOMIST P NASAL DROPS contains Xylometazoline which belongs to the group of medicines called Nasal decongestants. It is used in children (aged between 1-11 years) to provide relief from nasal congestion caused due to common cold, sinusitis (inflammation of the sinuses) or allergic rhinitis (an allergic condition).
Always use XYLOMIST P NASAL DROPS as directed by your physician. It is for intranasal use only. Do not use XYLOMIST P NASAL DROPS for more than 10 days to your child without consulting your doctor.
Before using XYLOMIST P NASAL DROPS inform your doctor if your child has heart problems or thyroid problems. You must also inform your doctor if your child has any other problems in the nasal tract apart from nasal congestion such as nasal inflammation, nasal dryness or any recent surgery in the nose.
XYLOMIST P NASAL DROPS should not be used in adults unless recommended by a doctor. The most common side effects of using XYLOMIST P NASAL DROPS are irritation or burning sensation after application and nasal dryness. Consult your doctor if they bother your child.
Uses Of XYLOMIST P NASAL DROPS
It is used in children (aged between 1-11 years) to provide relief from:
- Nasal congestion (blocked nose)
How XYLOMIST P NASAL DROPS Works
XYLOMIST P NASAL DROPS opens and clears the nasal passages. It works by narrowing down the blood vessels supplying the nasal passage. This helps swollen blood vessels of the nasal tract to return to its normal size which allows the air to pass through the nostrils more freely. It also reduces excessive nasal secretions and provides temporary relief from nasal inflammation, swelling and discomfort.
How to use XYLOMIST P NASAL DROPS
Always use XYLOMIST P NASAL DROPS as directed by your physician. It is for intranasal use only.
For Nasal Drops: Gently instill few drops of this medicine into each nostril. Clean the dropper after application.
For Nasal Spray: Insert the spray nozzle inside the affected nostril. Press the pump to release the spray and sniff at the same time. Repeat the same to the other nostril if required. Clean the nozzle after application.
To avoid possible spread of infection, this pack should only be used by a single person. Do not use XYLOMIST P NASAL DROPS for more than 10 days without consulting your doctor. Discard the unused portion after 28 days of opening it.
Side Effects Of XYLOMIST P NASAL DROPS
Common
- dry nose
- nose discomfort
- headache
- nausea
- irritation or burning sensation after application
Uncommon
- nosebleeds
Rare
Stop using XYLOMIST P NASAL DROPS and contact your doctor immediately if your child experiences any of the following side effects:
- severe allergic reactions (such as swelling of the face, lips, tongue, and/or throat which can lead to difficulty in breathing or swallowing)
- restlessness, hallucination and problems in sleeping
How To Manage Side Effects
Headache:
Apply pain-relieving balm on your child’s forehead. Consult your doctor if headache worsens.
Nausea:
Provide simple meals to your child. Make sure that they do not eat oil rich or spicy foods. Consult your doctor if nausea worsens.
Warning & Precautions
Pregnancy
XYLOMIST P NASAL DROPS is intended for use only in the children. Therefore, it should not be used in adults unless recommended by a doctor.
Breastfeeding
XYLOMIST P NASAL DROPS is intended for use only in the children. Therefore, it should not be used in adults unless recommended by a doctor.
Driving and Using Machines
XYLOMIST P NASAL DROPS does not affect your child’s ability to drive or operate any heavy tools.
Allergy
Do not use XYLOMIST P NASAL DROPS if your child is allergic to Xylometazoline or to any other ingredients of this medicine.
Heart Disease
XYLOMIST P NASAL DROPS should be used with caution in children with heart disease (such as hypertension, prolonged QT syndrome). Therefore, consult your doctor before administration.
Others
XYLOMIST P NASAL DROPS is not recommended for use if your child:
- has any inflammation in the nasal passages
- recently had a neurosurgery or surgery in their nose
- has closed angle glaucoma (increased pressure within the eyes)
- has chronic nasal inflammation and nasal dryness (such as rhinitis sicca or atrophic rhinitis)
- has phaeochromocytoma (a rare tumor of the adrenal glands)
Before using XYLOMIST P NASAL DROPS inform your doctor if your child has:
- diabetes
- hyperthyroidism (overactive thyroid gland)
- an enlarged prostate gland
Use in pediatrics:
XYLOMIST P NASAL DROPS can be used in children and adolescents aged between 1-11 years. It is not recommended for use in infants aged below 1 year. Therefore, consult your doctor for advice before administration.
Use in geriatrics:
XYLOMIST P NASAL DROPS is intended for use only in the children. Therefore, it should not be used in adults unless recommended by a doctor.
Interactions
A. Drug-Drug interactions:
Before using XYLOMIST P NASAL DROPS, inform your doctor if your child is taking any of the following medicines:
- antidepressants (used to manage depression) such as monoamine oxidase inhibitors (Ex. moclobemide, isocarboxazid, phenelzine and tranylcypromine), tricyclic antidepressants (Ex. amitriptyline, nortriptyline), lithium, fluoxetine, sertraline, citalopram, escitalopram etc
- medicines used to control blood pressure such as alpha blockers (Ex. prazosin, terazocin) or beta blockers (Ex. propranolol, atenolol)
- timolol, betaxolol (used to manage glaucoma in the eye)
- appetite suppressants (used for suppressing hunger) Ex. phentermine
- oxytocin (a medicine used during childbirth)
- ergot alkaloids (used for migraine headache) Ex. ergotamine
Overdosage:
If your child accidentally swallowed the medicine or applied too much of XYLOMIST P NASAL DROPS, consult your doctor immediately. Symptoms of overdosage might include severe dizziness, increased sweating, severely lowered body temperature, headache, slow heart rate, hypertension or difficulty in breathing.
Synopsis
| Drug | : | Xylometazoline |
| Pharmacological Category | : | Alpha-Adrenergic Agonist |
| Therapeutic Indication | : | Nasal congestion, sinusitis, perennial allergic rhinitis |
| Dosage Forms | : | Nasal Drops, Nasal Spray |
More Information
- Keep XYLOMIST P NASAL DROPS out of reach to children
- Store XYLOMIST P NASAL DROPS at room temperature
FAQs About XYLOMIST P NASAL DROPS
What is the use of XYLOMIST P NASAL DROPS?
XYLOMIST P NASAL DROPS is used to provide relief from nasal congestion caused due to common cold, sinusitis or allergic rhinitis.
Can XYLOMIST P NASAL DROPS be used every day?
Use XYLOMIST P NASAL DROPS for the duration prescribed by your doctor. Do not use XYLOMIST P NASAL DROPS for more than 10 days in your child without consulting your doctor. Prolonged use of XYLOMIST P NASAL DROPS may worsen the nasal congestion.
Is it safe to use XYLOMIST P NASAL DROPS?
Yes. XYLOMIST P NASAL DROPS is one of the safe and well tolerated medicine. It does not cause any harmful side effects. It may cause local irritation or burning sensation after application which is quite normal and disappears after few minutes.
What are the side effects of XYLOMIST P NASAL DROPS?
The most common side effects of using XYLOMIST P NASAL DROPS are irritation or burning sensation after application and nasal dryness. Consult your doctor if they bother your child.
Can XYLOMIST P NASAL DROPS be used in children?
XYLOMIST P NASAL DROPS must be used in children aged between 1-11 years. It is not recommended for use in infants aged below 1 year. Therefore, consult your doctor for advice before administration.
Is XYLOMIST P NASAL DROPS an antihistamine?
XYLOMIST P NASAL DROPS is a sympathomimetic agonist. It directly acts on the alpha-adrenergic receptors of the blood vessels supplying the nasal tract and narrows them down. This reduces swelling of the nasal tract and allows the air to pass through the nostrils more freely.
How long it takes for XYLOMIST P NASAL DROPS to work?
XYLOMIST P NASAL DROPS may show its therapeutic effect after 5 to 10 minutes of application. It works by narrowing the blood vessels in the affected nasal lining and helps to provide relief from congestion.
Can XYLOMIST P NASAL DROPS cause rebound congestion?
Yes, XYLOMIST P NASAL DROPS may cause rebound congestion (worsening of congestion due to nasal decongestant sprays) if you use for more than the duration recommended by your doctor.
References
1. K.D. Tripathi. Adrenergic System and Drugs. Essential of Medical Pharmacology. 7th Edition. Page – 136.
2. Xylometazoline. ScienceDirect.com. [Accessed on 30th August 2022] https://www.sciencedirect.com/topics/medicine-and-dentistry/xylometazoline#:~:text=Clinical%20Pharmacology%3A,Therapeutic%20Effect%3A%20Decreased%20nasal%20congestion.
3. Varajini Joganathan , Bijan Beigi. Safety of the use of xylometazoline nasal spray in young children undergoing lacrimal surgery: an observational study. NIH. National Library of Medicine. National Center of Biotechnology Information. PubMed.gov. May 2018. [Accessed on 2nd September 2022] https://pubmed.ncbi.nlm.nih.gov/29077183/
4. F Castellano 1, G Mautone. Decongestant activity of a new formulation of xylometazoline nasal spray: a double-blind, randomized versus placebo and reference drugs controlled, dose-effect study. NIH. National Library of Medicine. National Center of Biotechnology Information. PubMed.gov. 2002. [Accessed on 2nd September 2022] https://pubmed.ncbi.nlm.nih.gov/12073765/
5. GlaxoSmithKline Consumer Healthcare (UK). Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 30th August 2022] https://www.medicines.org.uk/emc/files/pil.6156.pdf
6. GlaxoSmithKline Consumer Healthcare. Otrivin 0.05% Pediatric Nasal Drops. [Revised in October 2021]. [Accessed on 2nd September 2022] https://www.otrivin.co.in/content/dam/cf-consumer-healthcare/Otrivin/en_IN/Leaflets/IN-Otrivin_Paediatric_Product_Information_Leaflet.pdf
7. Otrivin 0.05% Pediatric Nasal Drops. Otrivin.co.in [Accessed on 30th August 2022] https://www.otrivin.co.in/nasal-spray-and-drops-name/pediatric-nasal-drops/
8. Otrivin 0.05% Pediatric Metered Dose Nasal Spray. Otrivin.me. [Accessed on 30th August 2022] https://www.otrivin.me/products/kids-nasal-spray/
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