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East West Pharma

Xpertyl 600mg Tablet 10'S

Cough And Cold
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    Introduction About XPERTYL 600MG TABLET

    XPERTYL 600MG TABLET contains Acetylcysteine, which belongs to the group of medicines called Mucolytics. It is used in adults to manage acute airway diseases such as bronchitis (inflammation of the mucous membrane in the airways), emphysema, mucoviscidosis (cystic fibrosis), and/or bronchiectasis (chronic widening of the airway passage).

    XPERTYL 600MG TABLET is not recommended for use in patients allergic to Acetylcysteine. It is also not recommended for use in patients with bronchial asthma. Before taking XPERTYL 600MG TABLET, inform your doctor if you have stomach ulcers, liver diseases (such as non-alcoholic fatty acid disease), or chronic kidney disease.

    XPERTYL 600MG TABLET should be used with caution by pregnant and breastfeeding women only if it is clearly necessary. This medicine is not recommended for use in children and adolescents (below 18 years) and is advised to be used with caution in elderly patients (aged above 60 years) after consulting your doctor. The most common side effects of taking XPERTYL 600MG TABLET are nausea and vomiting. Consult your doctor if any of these symptoms worsen.

    Uses Of XPERTYL 600MG TABLET

    • Used to manage acute airway diseases such as bronchitis, emphysema, mucoviscidosis, and/or bronchiectasis in adults

    How XPERTYL 600MG TABLET Works

    XPERTYL 600MG TABLET works by enhancing airway secretions and mucociliary function (a defense mechanism of the lungs that promotes movement and removal of excess mucus), which causes the mucus (phlegm) to become less sticky, resulting in its easy removal through cough, thus managing airway diseases in affected individuals.

    How to use XPERTYL 600MG TABLET

    Take XPERTYL 600MG TABLET as advised by your physician. Swallow the medicine with a glass. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.

    Side Effects Of XPERTYL 600MG TABLET

    Common

    • nausea
    • vomiting

    Uncommon

    • signs of a hypersensitivity reaction
    • headache
    • ringing in the ears
    • inflamed and sore mouth
    • diarrhoea
    • fever
    • low blood pressure
    • abdominal pain

    Rare

    • signs of bronchospasm (tightening of airways in the lungs), such as shortening of breath or difficulty breathing
    • impaired indigestion with symptoms of fullness in the upper abdomen, gastric pain, belching, nausea, and heartburn

    Stop taking XPERTYL 600MG TABLET and contact your doctor if you experience any of the following side effects: 

    • signs of shock such as a severe drop in blood pressure, paleness, restlessness, weak pulse, clammy skin, and/or decreased consciousness
    • signs of angioedema (sudden fluid accumulation in the skin and mucous membrane) such as swelling of the lips, throat, or tongue, difficulty breathing, itching, and/or skin rash

    How To Manage Side Effects

    Diarrhea

    Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult and inform your doctor if the symptom worsens.

    Headache

    If XPERTYL 600MG TABLET causes headaches, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking XPERTYL 600MG TABLET. If it lasts more than a week or becomes severe, then consult and inform your doctor.

    Nausea And Vomiting

    Try to take XPERTYL 600MG TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Avoid drinking coffee, alcohol, or smoking.  Consult your doctor if the symptom gets worse.

    Warning & Precautions

    Pregnancy

    Monitoring required

    XPERTYL 600MG TABLET should be used with caution by pregnant women only if it is clearly necessary. Consult your doctor before taking the medicine.

    Breastfeeding

    Monitoring required

    XPERTYL 600MG TABLET should be used with caution in breastfeeding women only if it is clearly necessary. Consult your doctor about taking the medicine.

    Driving and Using Machines

    Use with Caution

    XPERTYL 600MG TABLET is not likely to affect your ability to drive or use machines. Consult your doctor before taking the medicine.

    Kidney

    Use with Caution

    XPERTYL 600MG TABLET should be used with caution in patients with chronic kidney disease. Consult your doctor before taking the medicine.

    Liver

    Use with Caution

    XPERTYL 600MG TABLET should be used with caution in patients with liver diseases such as non-alcoholic fatty acid disease. Consult your doctor before taking the medicine.

    Allergy

    Contraindicated

    XPERTYL 600MG TABLET is not recommended for use in patients allergic to acetylcysteine, or any other ingredients of this medicine. Consult your doctor before taking the medicine.

    Lungs

    Contraindicated

    XPERTYL 600MG TABLET is not recommended for use in patients with lung diseases such as bronchial asthma. Consult your doctor before taking the medicine.

    Use In Pediatrics

    Contraindicated

    XPERTYL 600MG TABLET is not recommended for use in children and adolescents (below 18 years). Consult your doctor before administering the medicine to the child.

    Use In Geriatrics

    Use with Caution

    XPERTYL 600MG TABLET should be used with caution in elderly patients (aged above 60 years). Consult your doctor before taking the medicine.

    Others

    Before taking XPERTYL 600MG TABLET, inform your doctor if you: 

    • have had ulcers in your stomach

    Interactions

    A. Drug-Drug Interactions:

    Before taking XPERTYL 600MG TABLET, inform your doctor if you are taking any of the following medicines:

    • cough suppressants (medicines used to suppress cough reflex) Ex. benzonatate
    • nitro-glycerine (a medicine used to manage angina pectoris)
    • activated charcoal (a medicine used to manage poisoning)

    Overdosage:

    If you or anyone else accidentally takes too much of XPERTYL 600MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are nausea, vomiting, and diarrhea.

    Synopsis

    Drug :   Acetylcysteine
    Pharmacological Category :   Mucolytics
    Therapeutic Indication :   Acute airway diseases         
    Dosage Forms :   Capsule, Tablet, Effervescent Tablet, Injection, Granules, Injection, Solution, Syrup

    More Information

    Storage

    • Keep XPERTYL 600MG TABLET out of reach of children
    • Store XPERTYL 600MG TABLET below 25°C

    FAQs About XPERTYL 600MG TABLET

    Q: What XPERTYL 600MG TABLET is used for?

    A: XPERTYL 600MG TABLET is used in adults as a mucolytic (phlegm loosening medicine) to manage airway diseases such as bronchitis, emphysema, mucoviscidosis (cystic fibrosis), and bronchiectasis.

    Q: What happens if you take more XPERTYL 600MG TABLET than your required dose?

    A: If you or anyone else accidentally takes too much of XPERTYL 600MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are nausea, vomiting, and diarrhea.

    Q: Is it safe to use XPERTYL 600MG TABLET on pregnant and breastfeeding women?

    A: XPERTYL 600MG TABLET should be used with caution in pregnant women and breastfeeding women only if it is clearly necessary. Consult your doctor before taking the medicine.

    Q: How does XPERTYL 600MG TABLET work?

    A: XPERTYL 600MG TABLET works by enhancing airway secretions and mucociliary function (a defense mechanism of the lungs that promotes movement and removal of excess mucus), which causes the mucus (phlegm) to become less sticky, resulting in its easy removal through cough, thus managing airway diseases in affected individuals.

    Q: What precautions must be taken while using XPERTYL 600MG TABLET?

    A: Before taking XPERTYL 600MG TABLET, inform your doctor if you have liver disease, kidney disease, or have had ulcers in your stomach.

    References

    1. Laurence Brunton. Pulmonary Pharmacology. Goodman and Gillman’s The Pharmacological Basics of Therapeutics. Twelfth Edition. 2011. Page-1057.

    2. Micaely Cristina dos Santos Tenório, Nayara Gomes Graciliano, Fabiana Andréa Moura, Alane Cabral Menezes de Oliveira, Marília Oliveira Fonseca Goulart. N-Acetylcysteine (NAC): Impacts on Human Health. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. June 2021. [Accessed on 14th February 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234027/

    3. Manouchehr Khoshbaten, Akbar Aliasgarzadeh, Koorosh Masnadi, Mohammad K Tarzamani, Sara Farhang, Hosain Babaei, Javad Kiani, Maryam Zaare, Farzad Najafipoor. N-Acetylcysteine Improves Liver Function in Patients with Non-Alcoholic Fatty Liver Disease. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. March 2010. [Accessed on 14th February 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270338/

    4. Minyuan Ye, Weiyuan Lin,1 Jing Zheng, Shaopeng Lin. N-acetylcysteine for chronic kidney disease: a systematic review and meta-analysis. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. April 2021. [Accessed on 14th February 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129408/

    5. Mark F. McCarty and James J. DiNicolantonio. An increased need for dietary cysteine in support of glutathione synthesis may underlie the increased risk for mortality associated with low protein intake in the elderly. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. October 2015. [Accessed on 14th February 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129408/

    6. Elara Pharmaceuticals Limited. Electronic Medicines Compendium (EMC). [Revised in January 2022] [Accessed on 14th February 2024] https://www.medicines.org.uk/emc/files/pil.8576.pdf

    Useful Diagnostic Tests

    • Lung Function Tests
    • Complete Blood Count (CBC)/ Hemogram
    • Healthy Midlife Checkup
    • Men Health Checkup - Advanced
    • Complete Women Checkup
    • Senior Citizen Checkup-Female
    • Senior Citizen Checkup-Male
    • Women Health Checkup-Essential
    • Full Body Checkup-Gold
    • Elderly Checkup-Female
    • Elderly Checkup-Male
    • Full Body Checkup-Silver

    Author Details

    Written By Dr. Janet.C - Pharm.D
    Reviewed For Accuracy By Dr. Rajnikant - MBBS, MD (Physiology)
    Last updated on 08 Aug 2024 | 12:06 PM(IST)
    Lab updated