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Introduction About XEMBIL 20 TABLET
XEMBIL 20 TABLET is used to relieve the symptoms of hay fever (such as sneezing, itching, a runny and stuffy nose, and red or watery eyes) and other forms of allergic rhinitis. It is also used to manage itchy skin rashes (hives, or urticaria).
XEMBIL 20 TABLET contains Bilastine, which belongs to the group of medicines called Antihistamines. It works by stopping the binding of histamine (a chemical that is produced by the immune system) to its receptor in the body, and in severe cases, it inhibits the initiation of an allergic reaction.
XEMBIL 20 TABLET is not recommended for use in patients with a history of irregular heartbeats. Before taking XEMBIL 20 TABLET, inform your doctor if you have moderate or severe renal impairment or a personal or family history of heart problems.
XEMBIL 20 TABLET should not be used during pregnancy as a precautionary measure, and it should be used with caution in breast-feeding women. Consult your doctor before taking this medicine.
XEMBIL 20 TABLET is not recommended for use in children (less than 12 years of age). The most common side effects of taking XEMBIL 20 TABLET are headache, drowsiness, nasal irritation, and stomach pain. Consult your doctor if any of the side effects worsen.
Uses Of XEMBIL 20 TABLET
It is used to:
- Relieve symptoms of hay fever (such as sneezing, itching, a runny and stuffy nose, and red or watery eyes) and other forms of allergic reactions
- Manage itchy skin rashes (hives or urticaria).
How XEMBIL 20 TABLET Works
XEMBIL 20 TABLET works by stopping the binding of histamine (a chemical that is produced by the immune system) to its receptor in the body, and in severe cases, it inhibits the initiation of an allergic reaction.
How to use XEMBIL 20 TABLET
Take XEMBIL 20 TABLET as advised by your doctor. Swallow the medicine with enough water. Do not crush or chew the medicine. Try to take XEMBIL 20 TABLET daily at the same time in the evening. Your doctor will decide the correct dose and duration of XEMBIL 20 TABLET for you depending upon your age, body weight, and disease condition.
Side Effects Of XEMBIL 20 TABLET
Common
- Headache
- Drowsiness
- Rhinitis (nasal irritation)
- Allergic conjunctivitis (eye irritation)
- Stomach pain (abdominal or upper abdominal pain)
Uncommon
- Tiredness, dizziness, and a feeling of weakness
- Increased appetite, nausea, diarrhea, and indigestion
- Irregular heartbeat
- Increased weight
- Anxiety
- Dry or uncomfortable nose
- Belly pain
- Gastritis (inflammation of the stomach wall)
- Vertigo (a sense of spinning or dizziness)
- Thirsty, dry mouth
- Dyspnea (difficult breathing)
- Itching, eczema, and urticaria (hives)
- Cold sores (oral herpes)
- Fever
- Tinnitus (ringing in the ears)
- Difficulty sleeping
- Lip swelling
- Loss of consciousness
Rare
Stop taking XEMBIL 20 TABLET and contact your physician immediately if you experience any of the following side effects:
- Allergic reaction (signs include difficulty breathing, dizziness, collapsing or losing consciousness, swelling of the face, lips, tongue, or throat, and/or swelling and redness of the skin)
- Heart problems (signs include heart racing or slowing, cold, sweats, feeling faint, feeling the heartbeat, lightheadedness, nausea, and shortness of breath)
How To Manage Side Effects
Diarrhea
Drink plenty of clear fluids, like water, diluted fruit juices, or oral rehydration solutions, to stay hydrated. Avoid caffeinated or alcoholic beverages, as they can worsen dehydration. Gradually take bland, low-fiber foods like bananas, rice, applesauce, and toast to help firm up stools. Probiotics, found in yogurt or supplements, may help restore the balance of gut bacteria. Practice good hand hygiene to prevent the spread of infection. Consult your doctor if diarrhea worsens.
Dry Mouth
Sip water regularly throughout the day to keep your mouth moist. Use a humidifier in your home, especially in your bedroom, to add moisture to the air. Maintain good oral hygiene by brushing your teeth at least twice a day and flossing daily. Use fluoride toothpaste to help protect your teeth. Use an alcohol-free mouthwash, as alcohol can dry out the mouth. Reduce your intake of caffeine, alcohol, tobacco, spicy, and salty foods, which can worsen dry mouth. Chewing sugar-free gum or sucking on sugar-free candies can stimulate saliva production. Incorporate moist foods into your diet, such as soups and stews. Use a lip balm to prevent dry lips. If dry mouth persists, consult your doctor.
Headache
Ensure adequate fluid intake, as dehydration can cause headaches. Maintain a consistent sleep schedule, aiming for 7-9 hours of quality sleep per night. Eat balanced meals at regular intervals to avoid blood sugar fluctuations that can trigger headaches. Practice relaxation techniques such as meditation, yoga, or deep breathing exercises to reduce stress levels. Engage in regular physical exercise, which can help reduce the frequency and severity of headaches. Apply a cold pack or warm compress to the forehead or neck to alleviate pain. Consult your doctor if a headache persists.
Nausea And Vomiting
Stay hydrated with small sips of clear fluids like water, ginger ale, or electrolyte solutions. Avoid consuming large meals; instead, opt for bland, easy-to-digest foods. Ginger, peppermint, or chamomile tea may help soothe the stomach. Rest in a comfortable position, preferably with your head elevated, to ease symptoms. Consult your doctor if nausea persists.
Stomach Pain
Avoid spicy or fatty foods, caffeine, or alcohol that may exacerbate symptoms. Eat a bland diet consisting of easily digestible foods like rice, bananas, applesauce, and toast. Applying a heating pad or taking a warm bath can also help soothe abdominal muscles and alleviate discomfort. Drink plenty of fluids to stay hydrated but avoid excessive consumption to prevent further irritation. If stomach pain persists, consult your doctor.
Warning & Precautions
Pregnancy
ContraindicatedXEMBIL 20 TABLET should not be used during pregnancy as a precautionary measure. Consult your doctor before taking it.
Breastfeeding
Use with CautionXEMBIL 20 TABLET should be used with caution in breastfeeding women. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionXEMBIL 20 TABLET does not affect the driving performance of adults. Consult your doctor if you feel any side effects during management with XEMBIL 20 TABLET that may stop you from driving or using machines.
Alcohol
Consult your doctorXEMBIL 20 TABLET does not increase the drowsiness produced by alcohol. Consult your doctor before taking it.
Kidney
Use with CautionXEMBIL 20 TABLET should be used with caution in patients suffering from moderate to severe kidney impairment. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take XEMBIL 20 TABLET if you are allergic to bilastine or any of the other ingredients in this medicine.
Heart Disease
Consult your doctorXEMBIL 20 TABLET is not recommended for use in patients with a history of irregular heartbeat, and it should be used with caution in patients suffering from heart problems or a family history of heart problems. Consult your doctor before taking it.
Use In Pediatrics
ContraindicatedXEMBIL 20 TABLET is not recommended for use in children (less than 12 years of age). Consult your child’s doctor for advice.
Use In Geriatrics
SafeXEMBIL 20 TABLET can be used in elderly patients without any dose adjustments. Consult your doctor before taking it.
Interactions
A. Drug-Drug interactions:
- Antifungal (Ex. ketoconazole)
- Antibacterials (Ex. erythromycin, rifampicin)
- Anti-anginal (Ex. diltiazem)
- Immunosuppressant (Ex. cyclosporine)
- Anti-retroviral (Ex. ritonavir)
B. Drug-food interactions:
Avoid taking XEMBIL 20 TABLET with food or with grapefruit juice or other fruit juices, as this will decrease the effect of this medicine.
Overdosage:
If you or anyone else accidentally takes too much of XEMBIL 20 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of an overdose may include dizziness, headaches, and nausea.
Synopsis
| Drug | : | Bilastine |
| Pharmacological Category | : | Antihistamine |
| Therapeutic Indication | : | Seasonal Allergic Rhinitis, Chronic Spontaneous Urticaria |
| Dosage Forms | : | Tablet, Dispersible tablet, Oral Solution, Syrup |
More Information
Storage
- Keep XEMBIL 20 TABLET out of reach of children
- Store at room temperature
FAQs About XEMBIL 20 TABLET
Q: What is XEMBIL 20 TABLET used for?
A: XEMBIL 20 TABLET is used to relieve the symptoms of hay fever (such as sneezing, itchy, runny, blocked-up nose, and red and watery eyes) and other forms of allergic rhinitis, which is usually caused by an allergen such as pollen, dust, mold, or flakes of skin from certain animals. It is also used to manage itchy skin rashes (hives, or urticaria).
Q: Can XEMBIL 20 TABLET be used in pregnant women?
A: XEMBIL 20 TABLET should not be used during pregnancy as a precautionary measure. Consult your doctor for advice before taking XEMBIL 20 TABLET if you are pregnant or planning to get pregnant.
Q: Is XEMBIL 20 TABLET safe to use in patients with kidney impairment?
A: XEMBIL 20 TABLET should be used with caution in patients suffering from moderate to severe kidney impairment. Your doctor may regularly monitor your kidney function tests during the management of this medicine. Consult your doctor before taking XEMBIL 20 TABLET.
Q: What are the common side effects of XEMBIL 20 TABLET?
A: The most common side effects of taking XEMBIL 20 TABLET are headache, drowsiness, nasal rhinitis (nasal irritation), allergic conjunctivitis (eye irritation), and stomach pain. Consult your doctor if any of the side effects worsen.
Q: Can I drive or operate any machines after taking XEMBIL 20 TABLET?
A: XEMBIL 20 TABLET does not affect the driving performance of adults. Consult your doctor if you feel any side effects during management with XEMBIL 20 TABLET that may stop you from driving or using machines.
Q: Can I use XEMBIL 20 TABLET with children?
A: XEMBIL 20 TABLET is not recommended for use in children (less than 12 years of age). Consult your child’s doctor for advice.
Q: What should I avoid while taking XEMBIL 20 TABLET?
A: Avoid taking XEMBIL 20 TABLET with food or with grapefruit juice or other fruit juices, as this will decrease the effect of this medicine.
Q: What is the best time to take XEMBIL 20 TABLET?
A: Take XEMBIL 20 TABLET on an empty stomach (at least one hour before meals or two hours after meals) or as directed by the doctor.
Q: Is XEMBIL 20 TABLET safe for kidneys?
A: XEMBIL 20 TABLET should be used with caution in patients suffering from moderate to severe kidney impairment. Consult your doctor before taking it.
Q: Does XEMBIL 20 TABLET make you drowsy?
A: XEMBIL 20 TABLET makes drowsiness a common side effect. Ensure proper hydration, as dehydration can cause dizziness. Avoid excessive caffeine, alcohol, and high-sodium foods, which can exacerbate symptoms. Engage in physical therapy or vestibular rehabilitation exercises designed to improve balance and reduce dizziness or drowsiness. Move slowly when changing positions, such as standing up or lying down, to avoid triggering dizziness. Practice relaxation techniques such as deep breathing, meditation, or yoga to manage stress, which can contribute to dizziness. Consult your doctor if drowsiness persists.
Q: Can XEMBIL 20 TABLET be used for cold?
A: XEMBIL 20 TABLET is not used to manage colds caused by viruses. It is used to relieve the symptoms of hay fever (such as sneezing, itching, a runny and stuffy nose, and red or watery eyes) and other forms of allergic rhinitis. It is also used to manage itchy skin rashes (hives, or urticaria). Consult your doctor for advice.
References
1. Dan L. Longo, Anthony S. Fauci, Dennis L. Kasper, Stephen L. Hauser, J. Larry Jameson, and Joseph Loscalzo. Allergy, Clinical Immunology, and Rheumatology. Harrison’s Manual of Medicine. 18th edition. Page- 1064.
2. Aranjit Singh Randhawa, Norhayati Mohd Noor, Mohd Khairi Md Daud, and Baharudin Abdullah. Efficacy and Safety of Bilastine in the Treatment of Allergic Rhinitis: A Systematic Review and Meta-Analysis. Frontiers in Pharmacology. January 2022 [Accessed on 10th July 2024] https://www.frontiersin.org/articles/10.3389/fphar.2021.731201/full
3. Martin K., Marysia Tiongco-Recto, Erminia Ridolo, and Zoltan Novak. Bilastine: a lifetime companion for the treatment of allergies. Journal of Current Medical Research Opinion. October 2019. [Accessed on 10th July 2024] https://www.tandfonline.com/doi/full/10.1080/03007995.2019.1681134
4. Menarini Manufacturing Logistics and Services S.r.l. Electronic Medicines Compendium (EMC). [Revised in December 2020] [Accessed on 10th July 2024] https://www.medicines.org.uk/emc/files/pil.4551.pdf
5. Aralez Pharmaceuticals Trading (DAC). Blexten (Bilastine 20 mg tablet). [Revised in July 2018] [Accessed on 10th July 2024] https://pdf.hres.ca/dpd_pm/00046279.PDF
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Total IGE
- Wheeze/Rhinitis Comprehensive Panel Adult
- Basic Allergy Package
- Absolute Eosinophil Count, Blood
- Allergy Comprehensive Profile
- Allergy Post Screening Profile
- Peripheral Smear Examination By Pathologist
- Full Body Checkup - Gold
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