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Introduction About VOGLI RAPID M 0.5MG TABLET
VOGLI RAPID M 0.5MG TABLET is a combination of Metformin, Repaglinide and Voglibose which belongs to a group of medicines called Antidiabetic agents. It is used to lower blood sugar in patients with type 2 diabetes mellitus whose blood sugar levels cannot be controlled by diet and exercise alone (monotherapy). Along management with VOGLI RAPID M 0.5MG TABLET follow regular exercise and diet plan as advised by the doctor to achieve better results.
Metformin is a biguanide derivative producing an antihyperglycemic effect has no effects on the pancreatic beta cells. The mode of action of metformin is not fully understood. It has been postulated that metformin might potentiate the effect of insulin or that it might enhance the effect of insulin on the peripheral receptor site. This increased sensitivity seems to follow an increase in the number of insulin receptors on cell surface membranes. Repaglinide helps the body release more insulin when your blood sugar is high. This helps improve your blood sugar control. Voglibose competitively and reversibly inhibits the alpha glucosidase enzymes in the brush border of the small intestine.
VOGLI RAPID M 0.5MG TABLET is not recommended if you have unstable and/or insulin-dependent (Type I) diabetes mellitus, metabolic acidosis, a history of lactic acidosis, stressed, have a severe infection or are experiencing trauma and gastrointestinal obstruction. Before taking inform your doctor if you are scheduled for surgery, x-ray or scanning procedures and vitamin B12 or folic acid deficiency. VOGLI RAPID M 0.5MG TABLET is not recommended for pregnant and breastfeeding women. Safety and effectiveness of VOGLI RAPID M 0.5MG TABLET in children and adolescents have not been established.
Consumption of alcohol is not recommended while taking VOGLI RAPID M 0.5MG TABLET. The most common side effects of taking VOGLI RAPID M 0.5MG TABLET are diarrhea, nausea, upset stomach, abdominal bloating, gas, loss of appetite, visual disturbance and constipation. Contact your doctor if any of the above side effects worsen or persists for a longer duration.
Uses Of VOGLI RAPID M 0.5MG TABLET
- It is used to lower blood sugar in patients with type 2 diabetes mellitus whose blood sugar levels cannot be controlled by diet and exercise alone
How VOGLI RAPID M 0.5MG TABLET Works
VOGLI RAPID M 0.5MG TABLET is a combination of Metformin, Repaglinide and Metformin which helps to lower blood glucose levels. Metformin is a biguanide derivative producing an antihyperglycemic effect has no effects on the pancreatic beta cells. The mode of action of metformin is not fully understood. It has been postulated that metformin might potentiate the effect of insulin or that it might enhance the effect of insulin on the peripheral receptor site. This increased sensitivity seems to follow an increase in the number of insulin receptors on cell surface membranes. Repaglinide helps the body release more insulin when your blood sugar is high. This helps improve your blood sugar control. Voglibose competitively and reversibly inhibits the alpha glucosidase enzymes in the brush border of the small intestine.
How to use VOGLI RAPID M 0.5MG TABLET
Take VOGLI RAPID M 0.5MG TABLET as advised by your physician. Swallow VOGLI RAPID M 0.5MG TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the right dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking VOGLI RAPID M 0.5MG TABLET without informing your doctor.
Side Effects Of VOGLI RAPID M 0.5MG TABLET
Common
- diarrhea
- nausea
- upset stomach, abdominal bloating, gas
- loss of appetite
- visual disturbance
- constipation
- cold sweat, cool pale skin, headache, rapid heartbeat, feeling sick and/or difficulty in concentrating (hypoglycemia)
- increased urination, feeling thirsty, dry skin and dry mouth (hyperglycemia)
Uncommon
- liver dysfunction
- itching, redness, rash, hives
- vomiting
Stop taking VOGLI RAPID M 0.5MG TABLET and consult your doctor immediately, if you experience:
- sudden severe headache or worsening of headache, dizziness, tremors, fatigue or increased sweating
- sudden partial or complete loss of vision
- chest pain or pressure, and/or shortness of breath
How To Manage Side Effects
Hypoglycemia
Eat or drink 15 to 20 grams of fast-acting carbohydrates. These are sugary foods or drinks without protein or fat that are easily converted to sugar in the body. Have a snack or meal.
Warning & Precautions
Pregnancy
ContraindicatedVOGLI RAPID M 0.5MG TABLET is not recommended for use in pregnant women. Consult your doctor before taking the medicine.
Breastfeeding
ContraindicatedVOGLI RAPID M 0.5MG TABLET is not recommended for breastfeeding women as it may pass through breast milk. Consult your doctor before taking VOGLI RAPID M 0.5MG TABLET.
Driving and Using Machines
Use with CautionDo not drive or use any tools or machines, if you experience signs of hypoglycemia after taking VOGLI RAPID M 0.5MG TABLET.
Alcohol
ContraindicatedConsumption of alcohol is not recommended while taking VOGLI RAPID M 0.5MG TABLET.
Kidney
Consult your doctorVOGLI RAPID M 0.5MG TABLET is not recommended for patients with kidney disease or impairment. It should be used with caution in patients with history of kidney disease. Consult your doctor before taking VOGLI RAPID M 0.5MG TABLET.
Liver
Consult your doctorVOGLI RAPID M 0.5MG TABLET is not recommended for patients with severe liver dysfunction or liver disease. It should be used with caution in patients with liver disease. Consult your doctor before taking VOGLI RAPID M 0.5MG TABLET.
Allergy
ContraindicatedDo not take VOGLI RAPID M 0.5MG TABLET if you are allergic (hypersensitive) to Metformin, Repaglinide and Voglibose or any other ingredients of this medicine.
Heart Disease
Consult your doctorVOGLI RAPID M 0.5MG TABLET is not recommended for use if you have cardiovascular collapse (abrupt failure of blood circulation) or hypoxemia. It should be used with caution if you had heart attack or stroke. Consult your doctor before taking VOGLI RAPID M 0.5MG TABLET.
Use In Pediatrics
Consult your doctorSafety and effectiveness of VOGLI RAPID M 0.5MG TABLET in children and adolescents have not been established. Hence it is not recommended for use in children and adolescents below 18 years of age. Consult your doctor before taking the medicine.
Use In Geriatrics
Use with CautionVOGLI RAPID M 0.5MG TABLET should be used with caution in elderly patients above 65 years of age. If needed dosage adjustment can be done patients with renal and hepatic impairment. Consult your doctor before taking the medicine.
Others
VOGLI RAPID M 0.5MG TABLET is not recommended for use, if you have:
- unstable and/or insulin-dependent (Type I) diabetes mellitus
- metabolic acidosis (including diabetic ketoacidosis, with or without coma, history of ketoacidosis with or without coma)
- a history of lactic acidosis (too much acid in the blood)
- an x-ray procedure with injection of dyes (iodinated contrast materials)
- stressed, have a severe infection or are experiencing trauma
- severe dehydration (have lost a lot of water from your body)
- gastrointestinal obstruction or predisposed to it
Before taking VOGLI RAPID M 0.5MG TABLET inform your doctor if you:
- are scheduled for surgery, x-ray or scanning procedures
- have vitamin B12 or folic acid deficiency
- have hypothyroidism (low levels of thyroid hormones)
- have history of laparotomy or ileus
- have chronic intestinal disease accompanied by disturbance in digestion and absorption
- have Roemheld syndrome, severe hernia, stenosis, and ulcer of the large intestine
Interactions
A. Drug-Drug interactions:
Before taking VOGLI RAPID M 0.5MG TABLET inform to your doctor if you are taking any of these following medicines:
- other diabetes medicines such as glyburide, repaglinide
- furosemide used for oedema (fluid retention) and high blood pressure
- nifedipine (used for high blood pressure, angina, Raynaud’s phenomenon)
- cationic medicines (e.g., amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, and vancomycin)
- blood thinners (warfarin, clopidogrel)
- corticosteroids (such as prednisone)
- phenothiazines (antipsychotic medicine)
- thyroid hormone replacement medicines (levothyroxine)
- estrogens or estrogens plus progestogen (female hormones)
- oral contraceptives
- phenytoin (medicine used for epilepsy)
- nicotinic acid (medicine use for niacin deficiency)
- medicines for asthma such as salbutamol or formoterol (beta-2-agonists)
- gemfibrozil (used to manage high blood fats)
- danazol (used for breast cysts and endometriosis)
- itraconazole, ketoconazole (used to manage fungal infection)
- cyclosporine (used to suppress the immune system)
- deferasirox (used to reduce chronic iron overload)
Overdosage:
If you or anyone else take too much of VOGLI RAPID M 0.5MG TABLET, contact your doctor immediately or go to a nearest hospital straight away. Symptoms of overdose are abdominal discomfort, diarrhoea, drowsiness, weakness, dizziness, malaise, headache, tiredness, rapid heartbeat, nervousness, shakiness, nausea and sweating.
Synopsis
| Drug | : | Metformin, Repaglinide, Voglibose |
| Pharmacological Category | : | Biguanides, Insulin secretagogue, Alpha-glucosidase |
| Therapeutic Indication | : | Type 2 Diabetes mellitus |
| Dosage Forms | : | Tablet |
More Information
- Keep VOGLI RAPID M 0.5MG TABLET out of reach of children
- Store at temperature below 25°C
FAQs About VOGLI RAPID M 0.5MG TABLET
Q: What is VOGLI RAPID M 0.5MG TABLET used for?
A: It is used to lower blood sugar in patients with type 2 diabetes mellitus whose blood sugar levels cannot be controlled by diet and exercise alone (monotherapy). Along management with VOGLI RAPID M 0.5MG TABLET follow regular exercise and diet plan as advised by the doctor to achieve better results.
Q: Can I stop taking VOGLI RAPID M 0.5MG TABLET without consulting your doctor?
A: No. do not stop taking VOGLI RAPID M 0.5MG TABLET without consulting your doctor because it may lead to unwanted side effects.
Q: Can I consume alcohol while taking VOGLI RAPID M 0.5MG TABLET?
A: Consumption of alcohol is not recommended while taking VOGLI RAPID M 0.5MG TABLET. Consult your doctor for advice before taking the medicine.
Q: Will taking a higher dose of VOGLI RAPID M 0.5MG TABLET be more effective?
A: No, taking a higher dose of VOGLI RAPID M 0.5MG TABLET will not be effective. Always take the dose as advised by your physician.
Q: What precautions do I need to follow while taking VOGLI RAPID M 0.5MG TABLET?
A: VOGLI RAPID M 0.5MG TABLET is not recommended if you have type 1 diabetes, diabetic ketoacidosis, acute or chronic metabolic acidosis, history of lactic acidosis and severe dehydration. Before taking inform your doctor if you are scheduled for surgery, x-ray or scanning procedures and vitamin B12 or folic acid deficiency.
Q: What are the common side effects of VOGLI RAPID M 0.5MG TABLET?
A: The most common side effects of taking VOGLI RAPID M 0.5MG TABLET are diarrhea, nausea, upset stomach, abdominal bloating, gas, loss of appetite, visual disturbance and constipation. Contact your doctor if any of the above side effects worsen or persists for a longer duration.
Q: Can VOGLI RAPID M 0.5MG TABLET be used in pregnant women?
A: VOGLI RAPID M 0.5MG TABLET is not recommended for pregnant women. Consult your doctor before taking the medicine.
Q: Can VOGLI RAPID M 0.5MG TABLET be used for Children?
A: Safety and effectiveness of VOGLI RAPID M 0.5MG TABLET in children and adolescents have not been established. Consult your doctor before taking the medicine.
References
1. KD Tripathi MD. Hormones and related drugs. Essentials of medical pharmacology. Seventh edition. New Delhi, May 2013. Page – 274.
2. Ashok R. Kulkarni1, Sujay A. Kulkarni & Priya Y. Kulkarni. Beneficial Effect of Repaglinide & Voglibose Combination in the Treatment of Fasting & Post Prandial Hyperglycemia Among Diabetics in South Maharashtra. International Journal of Current Medical And Applied Sciences, 2019, January, 21(2), 25-29. [Accessed on Jan 23rd, 2024] https://www.ijcmaas.com/images/archieve/IJCMAAS_JAN_2019_VOL21_ISS2_03PDF.PDF
3. Teva Canada Limited. [Revised on Feb 15, 2019] [Accessed on Jan 23rd, 2024] https://pdf.hres.ca/dpd_pm/00049683.PDF
4. Novo Nordisk Canada Inc. [Revised on June 03, 2015] [Accessed on Jan 23rd, 2024] https://www.novonordisk.ca/content/dam/Canada/AFFILIATE/www-novonordisk-ca/OurProducts/PDF/gluconorm-product-monograph-english.pdf
5. Blue cross Laboratories. [Revised on April, 2021] [Accessed on Jan 23rd, 2024] https://bluecrosslabs.com/wp-content/uploads/2023/02/K-VOG_Tablets_PI.pdf
Useful Diagnostic Tests
- HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
- Blood Glucose Fasting (FBS)
- Post Prandial Blood Sugar (PPBS)
- Insulin-Fasting
- Netmeds Diabetic Checkup
- Advance Diabetes Monitoring (Senior Female)
- Jaanch Diabetic Profile Basic
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