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Introduction About VENTIREX A TABLET
VENTIREX A TABLET is a combination of Ambroxol, and N-Acetylcysteine which belongs to the group of medicines called Mucolytics. It is used to manage or manage symptoms of chronic obstructive pulmonary diseases (COPD), such as coughing, shortness of breath or wheezing, tracheobronchitis (inflammation of airways (trachea and bronchi)), emphysema with bronchitis pneumoconiosis, and chronic inflammatory pulmonary conditions.
It also manages bronchiectasis (widening of airways of lungs), and bronchitis with bronchospasm asthma (tightening of the muscles of the bronchi causing shortness of breath), acute exacerbations of bronchitis and cystic fibrosis (an inherited disorder characterised by build-up of thick mucus in lungs).
VENTIREX A TABLET should be used with caution in patients with asthma, history of bronchospasm, bronchial motor activity disorder along with a large production of secretion, severe liver disease, moderate to severe kidney, high blood pressure, congestive heart failure, peptic ulcers, bleeding problems, undergoing any surgeries, epilepsy (convulsions).
VENTIREX A TABLET should be used in pregnancy only when it is clearly needed. Contact your doctor before taking it. VENTIREX A TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk.
VENTIREX A TABLET is not recommended for use in children under the age of 6 years. The most common side effects of taking VENTIREX A TABLET are nausea, vomiting, stomach upset, diarrhea or constipation. Contact your doctor if symptoms do not improve.
Uses Of VENTIREX A TABLET
It manages:
- Chronic Obstructive Pulmonary Diseases (COPD)
- tracheobronchitis
- emphysema with bronchitis pneumoconiosis
- chronic inflammatory pulmonary conditions
- bronchiectasis
- bronchitis with bronchospasm asthma
- acute exacerbations of bronchitis
- cystic fibrosis
How VENTIREX A TABLET Works
VENTIREX A TABLET works by reducing the viscosity (thickness and stickiness) of the mucus (sputum) in the airways and makes it easier to expel (cough it out). Thus, it helps to breathe easily.
How to use VENTIREX A TABLET
Take VENTIREX A TABLET as advised by your physician. Swallow the whole medicine with a glass of water. Do not crush or chew the medicine. Depending on your age, body weight, disease condition, your doctor will fix the correct dose and duration for you.
Side Effects Of VENTIREX A TABLET
Common
- diarrhea
- nausea, vomiting
- stomach upset
- constipation
Rare
- rashes
- fever
- headache
- drowsiness
- low blood pressure
- liver problems
Stop taking VENTIREX A TABLET and contact your physician immediately if you experience any of the following side effects:
- serious allergic reactions such as rashes, hives, with or without fever, itching, difficulty in breathing, swelling of the face, tongue, and throat causing difficulty in breathing and swallowing and lesions on the mouth, throat, nose, eyes, and genitals
How To Manage Side Effects
Constipation
Eat fiber-rich food. Eat and exercise regularly. Contact your doctor if it persists.
Diarrhea
Drink plenty of water and fruit juice to keep yourself hydrated. Contact your doctor if the diarrhoea did not improve.
Nausea And Vomiting
Stick to simple meals. Avoid eating oily or spicy food. If the nausea and vomiting does not improve, consult your doctor.
Warning & Precautions
Pregnancy
Consult your doctorVENTIREX A TABLET should be used in pregnancy only when it is clearly needed. Contact your doctor before taking it.
Breastfeeding
ContraindicatedVENTIREX A TABLET is not recommended in breastfeeding women, for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking VENTIREX A TABLET.
Kidney
Use with CautionVENTIREX A TABLET should be used with caution in patients with moderate to severe kidney. Contact your doctor before taking VENTIREX A TABLET.
Liver
ContraindicatedVENTIREX A TABLET should be used with caution in patients with severe liver disease. Contact your doctor before taking VENTIREX A TABLET.
Allergy
ContraindicatedDo not take VENTIREX A TABLET if you are allergic to ambroxol or N-Acetylcysteine or to other ingredients of this medicine.
Lungs
Use with CautionVENTIREX A TABLET should be used with caution in patients with asthma, a history of bronchospasm, bronchial motor activity disorder along with a large production of secretion. Contact your doctor before taking VENTIREX A TABLET.
Heart Disease
Use with CautionVENTIREX A TABLET should be used with caution in patients with high blood pressure, congestive heart failure. Contact your doctor before taking VENTIREX A TABLET.
Others
Before taking VENTIREX A TABLET, inform your doctor if you have:
- peptic ulcer
- bleeding problems
- any surgeries
- epilepsy (convulsions)
- any blood test or urine test
Use in paediatrics:
VENTIREX A TABLET is not recommended in children under the age of 6 years. Contact your doctor before taking VENTIREX A TABLET.
Interactions
A. Drug - Drug interactions:
Before taking VENTIREX A TABLET inform your doctor if you are taking any of the following medicines:
- antibiotics (Ex. amoxicillin, cefuroxime, erythromycin, chloramphenicol, clarithromycin, demeclocycline, doxycycline, minocycline, tetracycline, vancomycin (medicines used for bacterial infection)
- antitussives like codeine (used to manage cough)
- nitroglycerin (medicine used to manage angina)
- activated charcoal (used to manage poisoning)
- chloroquine (medicine used to manage malaria)
- medications used for high blood pressure (Antihypertensive drugs) such as captopril, enalapril, lisinopril, ramipril, losartan, valsartan, diltiazem, amlodipine, hydrochlorothiazide, furosemide etc
- medications used to manage blood clotting (anticoagulant / antiplatelet drugs) such as aspirin, clopidogrel, dalteparin, enoxaparin, heparin, warfarin, etc.
- diclofenac, ibuprofen, naproxen (medicines used to reduce pain)
Overdosage:
If you or anyone else accidentally takes too much of VENTIREX A TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose may include nausea, vomiting, diarrhoea, allergic reactions, excessive salivary flow, retching, vomiting, and low blood pressure, restlessness, and diarrhoea.
Synopsis
| Drug | : | Ambroxol, N-Acetylcysteine |
| Pharmacological Category | : | Mucolytics |
| Therapeutic Indication | : | COPD (Chronic obstructive pulmonary disease) |
| Dosage Forms | : | Tablet, Capsule |
More Information
- Keep VENTIREX A TABLET out of reach of children.
- Store VENTIREX A TABLET below 30°C
FAQs About VENTIREX A TABLET
Q: What is VENTIREX A TABLET used for?
A: It is used to manage or manage symptoms of chronic obstructive pulmonary diseases (COPD), such as coughing, shortness of breath or wheezing. It is also used to manage tracheobronchitis (inflammation of airways (trachea and bronchi)), emphysema with bronchitis pneumoconiosis, chronic inflammatory pulmonary conditions, bronchiectasis (widening of airways of lungs), and bronchitis with bronchospasm asthma (tightening of the muscles of the bronchi causing shortness of breath), acute exacerbations of bronchitis and cystic fibrosis (an inherited disorder characterised by build-up of thick mucus in lungs). Consult your doctor before taking VENTIREX A TABLET.
Q: Is VENTIREX A TABLET safe in pregnancy?
A: VENTIREX A TABLET should be used in pregnancy only when it is clearly needed. Contact your doctor for more information before taking this medicine.
Q: How does VENTIREX A TABLET work?
A: VENTIREX A TABLETworks by reducing the viscosity (thickness and stickiness) of the mucus (sputum) in the airways and makes it easier to expel (cough it out). Thus, it helps to breathe easily.
Q: What are the side effects of taking VENTIREX A TABLET?
A: The most common side effects of taking VENTIREX A TABLET are nausea, vomiting, stomach upset, and diarrhea. Contact your doctor if you experience any side effects.
Q: Is VENTIREX A TABLET safe in children?
A: VENTIREX A TABLET is not recommended in children under the age of 6 years. Contact your doctor for more information before taking VENTIREX A TABLET.
References
1. KD. Tripathi. Drugs for Bronchial Cough and Asthma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 219.
2. Scaglione F, Petrini O. Mucoactive Agents in the Therapy of Upper Respiratory Airways Infections: Fair to Describe Them Just as Mucoactive? Clin Med Insights Ear Nose Throat. NIH, National Library of Medicine, National center for biotechnology information. Pubmed central. January 2019. [Accessed on 19th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328955/
3. Sadowska AM, Verbraecken J, Darquennes K, De Backer WA. Role of N-acetylcysteine in the management of COPD. International Journal of Chronic Obstructive Pulmonary Disease. NIH, National Library of Medicine, National center for biotechnology information. Pubmed central. December 2006. [Accessed on 19th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707813/
4. Bethesda (MD). Acetylcysteine. National Institute of Health. NLM. National centre for biotechnology information. PubChem. 2004. [Accessed on 19th September 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Acetylcysteine
5. Ershad M, Naji A, Vearrier D. N Acetylcysteine. National Institute of Health. NLM. National centre for biotechnology information. StatPearls. June 2022 [Accessed on 19th September 2022] https://www.ncbi.nlm.nih.gov/books/NBK537183/
6. Salutas Pharma GmbH. Ambroxol. [Revised in June 2016] [Accessed on 19th September 2022] https://www.ravimiregister.ee/Data/PIL_ENG/PIL_10403_ENG.pdf
7. Ambroxol HCL and N-Acetylcysteine. Mims.com [Accessed on 19th September 2022] https://www.mims.com/myanmar/drug/info/respo?type=full
8. Ambroxol. Mims.com [Accessed on 19th September 2022] https://www.mims.com/malaysia/drug/info/ambroxol?mtype=generic
9. N-Acetylcysteine. Mims.com [Accessed on 19th September 2022] https://www.mims.com/malaysia/drug/info/acetylcysteine?mtype=generic
10. Acetylcysteine. Rxlist.com [Accessed on 19th September 2022] https://www.rxlist.com/n-acetyl_cysteine/supplements.htm
12. Acetylcysteine. Drugs.com [Accessed on 19th September 2022] https://www.drugs.com/mtm/acetylcysteine.html
13. Mucoend-AM Tablet (Ambroxol + Acetylcysteine). Leeford Healthcare Ltd. [Accessed on 19th September 2022] https://www.leeford.in/product/1601/mucoend-am
14. RESPO CASPULES (Ambroxol Hydrochloride + Acetylcysteine). Zifam. [Accessed on 19th September 2022] https://www.zifammyanmar.com/products/respo/#read
15. Comelt-A Tablets (N-Acetyl L-Cysteine & Ambroxol Hydrochloride). Jabs Biotech. [Accessed on 19th September 2022] https://www.jabsbiotech.com/product/n-acetylcysteinenac-300mg-ambroxol-30mg
Useful Diagnostic Tests
- Liver Function Test
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