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Introduction About VELTAM PLUS TABLET
VELTAM PLUS TABLET is a combination of Dutasteride and Tamsulosin which belongs to the group of medicines called 5-Alpha reductase inhibitors and Alpha-blockers respectively. VELTAM PLUS TABLET is used to manage signs and symptoms of Benign Prostatic Hyperplasia (BPH) in men. Benign Prostatic Hyperplasia (also known as enlarged prostate) is a non-cancerous growth of prostate gland, which is predominantly caused by excessive production of a stress hormone called dihydrotestosterone (DHT) in men.
Symptoms of BPH includes urinary problems such as difficulty in passing urine, urinary incontinence (unintentional passing of urine), frequent urination at night and sexual dysfunction or painful ejaculation.
During this therapy, your doctor will regularly monitor your serum prostate-specific antigen (PSA) levels to detect the incidence of prostate cancer.
Before taking VELTAM PLUS TABLET inform your doctor if you have any liver or kidney problems. Both pregnant women and children should avoid handling the leaking medicine, because this medicine has a high potential to get absorbed through your skin and can affect the normal development of a male baby (especially during the first 16 weeks of pregnancy).
Usage of condom during sexual intercourse is recommended among fertile men to avoid conception. VELTAM PLUS TABLET is not recommended for use in children and adolescents under 18 years of age. VELTAM PLUS TABLET should be used with caution in elderly patients above 65 years of age.
The most common side effects of taking VELTAM PLUS TABLET are dizziness, enlargement of breast in men and decreased sex drive. Consult your doctor if any of the side effects bothers you.
Uses Of VELTAM PLUS TABLET
- Manage signs and symptoms of benign prostatic hyperplasia (BPH) in men
How VELTAM PLUS TABLET Works
VELTAM PLUS TABLET reduces the symptoms of benign prostatic hyperplasia, where dutasteride works by reducing the production of a stress hormone called dihydrotestosterone and tamsulosin works by relaxing the muscles surrounding the prostate gland, thus helps in shrinkage of prostate, making it easier for the urine to pass through and relieve the symptoms.
How to use VELTAM PLUS TABLET
Always take VELTAM PLUS TABLET as directed by your physician. Take this medicine with or without food, swallow the medicine as a whole and do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking VELTAM PLUS TABLET without informing your doctor.
Side Effects Of VELTAM PLUS TABLET
Common
- sexual impotence (unable to achieve or maintain an erection)
- decreased sex drive
- difficulty in ejaculation
- gynecomastia (breast enlargement or tenderness)
- dizziness
Uncommon
- heart failure (signs include shortness of breath, extreme tiredness and swelling in your ankles and legs)
- low blood pressure on standing
- weakness or loss of strength
- headache
- constipation, diarrhea
- nausea, vomiting
- fast heartbeat
- itchy, blocked or runny nose
- skin rash, hives, itching
- hair loss or hair growth
Rare
- swelling of the face, eyelids, lips, arms or legs
- fainting
Stop taking VELTAM PLUS TABLET and contact your doctor immediately if you experience any of the following side effects:
- signs of allergic reaction (such as skin rash, itching, hives, and swelling of face, eyelids, lips, arms or legs)
- stevens-johnson syndrome (a severe widespread rash with blisters and peeling skin, particularly around the mouth, nose, eyes and genitals)
How To Manage Side Effects
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any machines while you are feeling dizzy. Avoid consumption of alcohol as it can aggravate your dizziness. If the symptom persists for a longer time, contact your doctor for advice.
Nausea and vomiting:
Take this medicine with or just after a meal or snack and stick to simple meals and do not eat oil rich or spicy foods. Consult your doctor if the symptom does not improve.
Headache:
Apply hot or cold-water bag on your head. Try taking rest in a quiet and dark room. Drink tea or coffee. Consult your doctor if the symptom does not improve.
Constipation:
Take fiber rich foods in your diet such as fresh fruits, vegetables, whole grain cereals and drink plenty of fluids. Exercise more regularly and stay active. Consult your doctor if the symptom does not improve.
Warning & Precautions

Pregnancy
VELTAM PLUS TABLET is intended for use only in men. Pregnant women should not come in contact with VELTAM PLUS TABLET as it may cause potential abnormalities in male foetus.

Breastfeeding
VELTAM PLUS TABLET is intended for use only in men and therefore should not be used in breastfeeding women.

Driving and Using Machines
Do not drive or operate any machines if you experience dizziness while taking VELTAM PLUS TABLET.

Alcohol
Avoid consumption of alcohol while taking this medicine because it may cause excessive drowsiness. Consult your doctor before taking VELTAM PLUS TABLET.

Kidney
VELTAM PLUS TABLET should be used with caution if you have severe kidney disease. Consult your doctor for advice before taking VELTAM PLUS TABLET.

Liver
VELTAM PLUS TABLET is not recommended for use in patients having severe liver disease and it should be used with caution in patients with liver problems. Consult your doctor for advice before taking VELTAM PLUS TABLET.

Allergy
Do not take VELTAM PLUS TABLET if you are allergic to Tamsulosin or Dutasteride and other 5-alpha reductase inhibitors such as finasteride and soya or peanut.

Heart Disease
VELTAM PLUS TABLET is not recommended for use in patients with low blood pressure (which causes dizziness, lightheadedness or fainting (orthostatic hypotension)). Consult your doctor for advice before taking VELTAM PLUS TABLET.
Others
VELTAM PLUS TABLET is not recommended for you, if you:
- are a woman (because this medicine is for men only)
Before taking VELTAM PLUS TABLET, inform your doctor if you have:
- an upcoming cataract surgery
- blood test for PSA (Prostate Specific Antigen)
Use in pediatrics:
VELTAM PLUS TABLET is not recommended for use in children or adolescents less than 18 years of age. Consult your child’s doctor for advice.
Use in geriatrics:
VELTAM PLUS TABLET should be used with caution in elderly patients above 65 years of age. Consult with your doctor for advice before taking VELTAM PLUS TABLET.
Interactions
A. Drug-Drug interactions:
Before taking VELTAM PLUS TABLET inform to your doctor, if you are taking any of these medicines:
- other alpha blockers (used to manage enlarged prostate or high blood pressure) such as prazosin, doxazosin, terazosin
- medicines used to manage erectile dysfunction (Ex. vardenafil, sildenafil and tadalafil)
- medicines used to manage fungal infections (Ex. itraconazole, ketoconazole or terbinafine)
- diltiazem or verapamil (used to manage angina or high blood pressure)
- ritonavir or indinavir (used to manage HIV infection)
- paroxetine or nefazodone (medicine used to manage depression)
- cimetidine (medicine used to manage stomach ulcers)
- warfarin (used to manage blood clotting)
- erythromycin (used to manage bacterial infections)
- diclofenac (medicine used to manage pain or inflammation)
Overdosage:
If you or anyone else accidentally take too much of VELTAM PLUS TABLET, consult your doctor immediately. Overdosage may cause acute hypotension, nausea and vomiting.
Synopsis
Drug | : |
Dutasteride, Tamsulosin |
Pharmacological Category | : |
5-Alpha reductase inhibitors, Alpha-blockers |
Therapeutic Indication | : |
Benign Prostatic Hyperplasia |
Dosage Forms | : |
Tablet, Capsule |
More Information
- Keep VELTAM PLUS TABLET out of reach of children
- Store at room temperature
FAQs About VELTAM PLUS TABLET
Can VELTAM PLUS TABLET cause prostate cancer?
This medicine can increase the risk of prostate cancer and so your doctor would regularly monitor your serum prostate specific antigen (PSA) which is used to detect prostate cancer, in order to avoid any untoward side effects.
Can VELTAM PLUS TABLET cause infertility?
Yes, VELTAM PLUS TABLET can reduce sperm count, semen volume and movement also it can cause sexual impotence, decreased sex drive or difficulty in ejaculation in men. Consult your doctor if you experience any of these side effects.
Can VELTAM PLUS TABLET be used for erectile dysfunction?
Yes, VELTAM PLUS TABLET is intended to manage signs and symptoms of benign prostatic hyperplasia (BPH) and its associated symptoms such as urinary problems and erectile dysfunction or painful ejaculation.
Can VELTAM PLUS TABLET cause dizziness?
Yes, VELTAM PLUS TABLET can cause dizziness in some people. Try to rest and relax. Get enough sleep. Avoid driving or operating any machines while you are feeling dizzy. Avoid consumption of alcohol as it can aggravate your dizziness. If the symptom persists for a longer time, consult your doctor for advice.
Is VELTAM PLUS TABLET safe to use in patients with liver disease?
VELTAM PLUS TABLET is not recommended for use in patients having severe liver disease and it should be used with caution in patients with liver problems. Your doctor will adjust the dose based on the severity of the impairment and will monitor your liver function test periodically during management with VELTAM PLUS TABLET. Before taking this medicine, inform your doctor if you have any liver disease.
Can VELTAM PLUS TABLET be used in children?
VELTAM PLUS TABLET is not recommended for use in children or adolescents less than 18 years of age. Consult child’s doctor for advice before taking VELTAM PLUS TABLET. Doctor may consider the effective management in managing the condition.
References
1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page – 303.
2. KD. Tripathi. Antiadrenergic Drugs (Adrenergic Receptor Antagonists) and Drugs for Glaucoma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 142.
3. Peter J. Snyder. Androgens. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1205.
4. GlaxoSmithKline. Benign Prostatic Hyperplasia Trial With Dutasteride And Tamsulosin Combination Treatment. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in February 2017] [Accessed on 28th October 2022] https://www.clinicaltrials.gov/ct2/show/NCT00090103
5. Konstantinos Dimitropoulos and Stavros Gravas. Fixed-dose combination therapy with dutasteride and tamsulosin in the management of benign prostatic hyperplasia. NCBI; PMC US National Library of Medicine, National Institute of Health. February 2016. [Accessed on 28th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707422/
6. J Miller and TH Tarter. Combination therapy with dutasteride and tamsulosin for the treatment of symptomatic enlarged prostate. NCBI; PMC US National Library of Medicine, National Institute of Health. June 2009. [Accessed on 28th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697590/
7. Sibylle Marihart, Mike Harik and Bob Djavan. Dutasteride: A Review of Current Data on a Novel Dual Inhibitor of 5α Reductase. NCBI; PMC US National Library of Medicine, National Institute of Health. 2005. [Accessed on 28th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1550785/
8. Glenmark Pharmaceuticals Europe Limited. Laboratorios Leon Farma, SA. Electronic Medicines Compendium (EMC). [Revised in January 2020] [Accessed on 28th October 2022] https://www.medicines.org.uk/emc/files/pil.11336.pdf
9. Dr. Reddy’s Laboratories (UK) Ltd, Laboratorios Leon Farma, SA. Electronic Medicines Compendium (EMC). [Revised in January 2020] [Accessed on 28th October 2022] https://www.medicines.org.uk/emc/files/pil.11304.pdf
10. Cipla Ltd. Urimax D Tablets (Tamsulosin hydrochloride + Dutasteride). Ciplamed. [Revised in December 2013]. [Accessed on 28th October 2022] https://www.ciplamed.com/content/urimax-d-tablets
Useful Diagnostic Tests
- Prostate-specific antigen (PSA) test