Veloz D Capsule 10'S

Introduction About VELOZ D CAPSULE

Veloz D Capsule is commonly used in individuals who experience symptoms linked to excessive stomach acid, delayed gastric emptying, or gastroesophageal discomfort, such as bloating, acid regurgitation, or early fullness. This capsule is a combination of Rabeprazole (a proton pump inhibitor) and Domperidone (a prokinetic agent) designed to help manage acid secretion and improve stomach motility. It may be considered by individuals with sedentary lifestyles, irregular eating habits or those prone to functional dyspepsia.  

The rabeprazole component works by selectively inhibiting the gastric H?/K? ATPase enzyme system, reducing stomach acid production. Domperidone enhances gastrointestinal motility by blocking dopamine receptors in the gut. Together, they are often recommended in clinical guidelines for short-term relief of acid reflux symptoms and gastric slowing. This dual-action capsule is ideally used under medical guidance in adults with symptoms of non-ulcer dyspepsia, reflux-related discomfort, or chronic gastritis.

For best results, Veloz D Capsule should be taken 15 to 30 minutes before meals, typically once daily, or as prescribed. Swallow the capsule whole with water do not crush or chew. Patients should avoid lying down immediately after taking the medicine. Those on long-term use should have regular follow-ups to assess magnesium levels, bone health, and possible nutrient malabsorption. It is important to avoid co-administration with strong CYP3A4 inhibitors or antacids within 1 hour of dosing, unless advised by a healthcare provider.

Use in pregnancy or breastfeeding should only occur if clearly advised by a healthcare professional. While no major risks have been noted in limited studies, caution is recommended due to limited human data. Common side effects may include dry mouth, headache, dizziness, or mild diarrhoea. Rarely, prolonged use may be associated with B12 deficiency or altered liver enzymes. Patients with known cardiac rhythm disorders, kidney dysfunction, or electrolyte imbalances should use this product with additional caution.

Uses Of VELOZ D CAPSULE

• Peptic ulcer
• Gastro-Oesophageal Reflux Disease (GERD)

Benefits of VELOZ D CAPSULE

VELOZ D Capsule Relieves Acid Reflux and Heartburn

VELOZ D Capsule is specifically formulated to treat gastroesophageal reflux disease (GERD), a condition where stomach acid frequently flows back into the esophagus. This backflow causes uncomfortable symptoms such as heartburn and chest pain. The capsule combines rabeprazole, which reduces acid production, with domperidone, which helps move food through the digestive system. By targeting both acid control and stomach motility, VELOZ D Capsule effectively relieves symptoms like acidity, heartburn, and persistent irritation.

VELOZ D Capsule Prevents Gastric and Duodenal Ulcers

VELOZ D Capsule helps prevent the formation and recurrence of peptic ulcers in the stomach and upper intestine (duodenum). Rabeprazole, its key component, blocks acid production in the stomach, reducing the risk of damage to the stomach and intestinal lining. By maintaining a lower acid environment, the capsule not only aids in healing existing ulcers but also offers protection against future ulcer development, especially in individuals prone to these conditions

VELOZ D Capsule Improves Digestion and Reduces Bloating

The combination of rabeprazole and domperidone in VELOZ D Capsule enhances the digestive process and reduces bloating. Rabeprazole controls stomach acidity, while domperidone increases stomach emptying and motility, helping food and gas move smoothly through the digestive tract. This dual action relieves symptoms of indigestion, fullness, and abdominal discomfort—improving overall digestive comfort for those suffering from chronic gastric complaints.

How VELOZ D CAPSULE Works

Veloz D Capsule Mechanism of Action

Veloz D Capsule works through a dual mechanism to manage both excessive acid secretion and delayed gastric emptying. It contains Rabeprazole, a proton pump inhibitor (PPI), which inhibits the H?/K?-ATPase enzyme in the stomach lining this significantly reduces the production of stomach acid. The second component, Domperidone, acts as a prokinetic agent by blocking dopamine receptors in the gut and upper digestive tract, thereby enhancing gastric motility. Together, this combination helps relieve symptoms like acidity, bloating, nausea, and reflux by reducing acid levels and accelerating stomach emptying.

 Veloz D Capsule: Acid Suppressor Action

As an acid suppressor, Veloz D reduces the acid secreted in the stomach to control symptoms like heartburn, sour burps, acid regurgitation, and burning sensation in the chest. The Rabeprazole component blocks the proton pumps in the parietal cells of the stomach that release acid. This inhibition leads to a sustained reduction in gastric acid levels, making the capsule especially effective when acidity is triggered by heavy meals, stress, or irregular eating patterns. Regular use as prescribed can help protect the oesophagus from acid damage and ease digestion.

Veloz D Capsule: Stomach Acid Blocker Mechanism

Veloz D’s stomach acid blocking effect comes from its active ingredient Rabeprazole, which targets the final step of acid secretion in the stomach. It binds irreversibly to the gastric proton pumps, thereby preventing hydrogen ion (H?) exchange this is crucial for acid formation. By reducing acid output at the source, Rabeprazole helps maintain a healthier gastric pH and lowers the chance of acid reflux and mucosal irritation. This mechanism provides lasting relief from acidity, especially in patients who experience symptoms at night or after large meals.

How Does Veloz D Capsule Regulate Gastric Emptying

Veloz D also functions as a gastric motility regulator, thanks to Domperidone, its prokinetic component. This ingredient stimulates the movement of food through the stomach and intestines by enhancing muscle contractions in the upper digestive tract. By blocking dopamine receptors in the gut, Domperidone reduces the inhibitory effect on the GI tract, allowing food to pass smoothly. This action helps in reducing bloating, early fullness, nausea, and burping especially in people with delayed gastric emptying or non-ulcer dyspepsia.

How to use VELOZ D CAPSULE

Veloz D Capsule Dosage Guidelines

• It is commonly taken once daily, or as prescribed by your healthcare provider.
• Do not self-adjust the dose without medical consultation.
• Skipping doses or taking more than recommended may interfere with its effectiveness.
• Always follow your doctor’s instructions carefully for the best results.

Veloz D Capsule Administration Instructions

• Take the capsule exactly as prescribed
• Swallow whole with water; do not open or chew
• Follow a regular time each day for consistent benefits
• Inform your doctor about any other medications or supplements
• Avoid self-medicating or discontinuing without guidance

These instructions help optimize the capsule’s effect on acid control and digestive motility.

How to Take Veloz D Capsule – Before or After Food

• Take Veloz D Capsule before food – ideally 15 to 30 minutes prior to a meal, preferably in the morning.
• This timing helps in better regulation of stomach acid and coordinated gastric emptying.
• Taking it before meals allows the medicine to work more efficiently in reducing acid buildup and supporting digestion.
• Do not take it on a full stomach, as it may reduce its effectiveness.
• If you're unsure about the best time to take it, consult your doctor or pharmacist for personalized advice.

What if I forgot to take VELOZ D CAPSULE

• Take the missed dose as soon as you remember, ideally before your next meal if it's not too late in the day.
• Skip the missed dose if it’s almost time for your next scheduled dose do not take two capsules at once to make up for it.
• Avoid doubling the dose, as this may increase the risk of side effects like headache, dizziness, or diarrhoea.
• Try to maintain a fixed routine by taking the capsule at the same time every day this helps improve consistency and results.
• Set daily reminders or alarms if you tend to forget your medication frequently.
• Inform your doctor if you miss multiple doses or if you’re unsure about when to resume the medicine.

Overdose

If you or anyone else take too much of VELOZ D CAPSULE, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms are altered consciousness, agitation, convulsions, disorientation, sleepiness and extrapyramidal reactions (such as rigidity, tremor, drooling).

Side Effects Of VELOZ D CAPSULE

Common side effects of VELOZ D CAPSULE

• nausea, vomiting
• diarrhoea, constipation, stomach pain, flatulence
• cough, sore throat, runny nose
• back pain
• headache, dizziness
• dry mouth
• benign polyps in the stomach
• indigestion, belching in the stomach (excess air accumulation in the stomach)
• urinary tract infection

When to Seek Medical Attention:

Stop taking VELOZ D CAPSULE and contact your doctor immediately if you experience the following side effects:

• Chest pain or tightness
• Irregular or fast heartbeat
• Severe dizziness or fainting
• Breathing difficulty or shortness of breath
• Swelling of face, lips, tongue, or throat (possible allergic reaction)
• Severe stomach pain, vomiting blood, or black stools
• Persistent nausea, muscle cramps, or unusual fatigue
• Yellowing of eyes or skin (possible liver concern)

How To Manage Side Effects

Diarrhea

• Increase fluid intake: Drink plenty of water, oral rehydration solutions, or clear broths to counter fluid loss.
• Eat light and low-fiber foods: Opt for bananas, rice, applesauce, and toast (“BRAT” diet) until symptoms subside.
• Avoid dairy, caffeine, and fatty foods: These can make diarrhea worse; reintroduce them slowly once you feel better.
• Maintain good hygiene: Wash hands frequently to prevent spreading or acquiring infections.
• Contact your doctor if severe: See a healthcare provider for prolonged or severe diarrhea, or if you notice blood in your stool.

Headache

• Rest in a quiet, dark room: Reduce stimulation and lie down if possible to relieve headache pressure.
• Stay hydrated: Drink water consistently throughout the day, as dehydration can trigger or worsen headaches.
• Use a cold compress: Place a cool cloth or ice pack on your forehead for relief.
• Over-the-counter pain relief: Take paracetamol or doctor-recommended painkillers if needed and safe for you.

Nausea And Vomiting

• Take medication with food: Swallow your capsule after a small meal or snack to reduce stomach upset.
• Stay hydrated: Sip clear fluids (like water or ginger tea) regularly to ease nausea and prevent dehydration.
• Avoid strong odors and spicy foods: Stick to bland, easy-to-digest meals and limit exposure to triggers that worsen nausea.
• Rest in an upright position: After taking your medicine, remain sitting or slightly elevated—lying flat can enhance nausea.
• Use doctor-recommended remedies: If persistent, your doctor may advise anti-nausea medications or natural aids like ginger.

Warning & Precautions

Pregnancy

Contraindicated

VELOZ D CAPSULE is not recommended for use in pregnant women. Consult your doctor before taking it.

Breastfeeding

Contraindicated

VELOZ D CAPSULE is not recommended for use in breast-feeding women. Consult your doctor before taking it.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you experience sleepiness, confusion or less control over your movements.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking VELOZ D CAPSULE, as it could aggravate your existing condition.

Kidney

Contraindicated

VELOZ D CAPSULE is not recommended for use in patients with kidney impairment. Consult your doctor before taking it.

Liver

Consult your doctor

VELOZ D CAPSULE is not recommended for use in patients with moderate or severe liver impairment and it should be used with caution in patients with liver problems.

Allergy

Contraindicated

Do not take VELOZ D CAPSULE if you are allergic to Domperidone or Rabeprazole or any other ingredients of this medicine.

Heart Disease

Contraindicated

VELOZ D CAPSULE is not recommended for use in patients with heart problems such as prolongation of QT interval or congestive heart failure.

Use In Pediatrics

Contraindicated

VELOZ D CAPSULE is not recommended for use in children and adolescents (aged less than 18 years) due to lack of safety and effectiveness.  

Use In Geriatrics

Use with Caution

VELOZ D CAPSULE should be taken with caution in elderly patients (aged 65 years or above).  Consult your doctor before taking it.

Other Warnings for VELOZ D CAPSULE

Before taking VELOZ D CAPSULE, inform your physician if you:

• Have osteoporosis
• Have vitamin B12 deficiency (sore tongue, mouth ulcers, pale skin, depression)
• Are going to test Chromogranin A level

Who should not take [GBNKEYWORD

VELOZ D CAPSULE is not recommended for use if you:

• Have bloody stools or bleeding in the gut
• Have blockage or tear in the intestines
• Have severe fluid or electrolyte disturbances
• Have prolactinoma
• Have phenylketonuria  
• Have problem that causes low levels of potassium or magnesium or high levels of potassium in the blood
• Have hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsorption

Safety Advice

Important Precautions Before You Start Veloz D Capsule

• Consult your doctor before starting, especially if you have chronic conditions like liver, kidney, or heart disease.
• Inform your doctor about all current medications, including over-the-counter drugs, supplements, or herbal products to avoid harmful interactions.
• Avoid use if allergic to rabeprazole, domperidone, or similar medications.
• Do not use in children unless specifically prescribed by a paediatric specialist.
• Limit long-term use unless advised, as it may lead to side effects like vitamin B12 deficiency or altered magnesium levels.
• Avoid alcohol and tobacco, which can worsen gastric issues and interfere with medicine effectiveness.
• Check with your doctor if you're pregnant or breastfeeding, as Veloz D should be used with caution in these conditions.
• Use with caution in elderly patients, as they may be more sensitive to side effects like dizziness or electrolyte imbalance.
• Do not take along with antacids at the same time; leave a gap of at least 1–2 hours.

Signs You Need Medical Help Right Away While Taking Veloz D Capsule

• Severe stomach pain, persistent vomiting, or vomiting blood.
• Black, tarry, or bloody stools indicating possible gastrointestinal bleeding.
• Fast, irregular heartbeat, palpitations, or sudden chest discomfort.
• Severe dizziness, fainting, or confusion.
• Swelling of the face, lips, or throat, or difficulty breathing may suggest an allergic reaction.
• Muscle cramps, tremors, or unusual weakness, possibly due to low magnesium levels.
• Yellowing of eyes or skin (jaundice), which may indicate liver-related issues.
• Unexplained weight loss, persistent fatigue, or lack of appetite.
• Any new or worsening symptoms that are not explained or expected during use.

Diet and Lifestyle Advice

Meal Planning and Timing While on Veloz D Capsule

• Take Veloz D 15–30 minutes before meals, preferably in the morning, to maximize acid control and improve gastric emptying.
• Stick to regular meal timings – Skipping meals or eating at irregular hours may worsen acid reflux and reduce the capsule’s effectiveness.
• Prefer smaller, more frequent meals instead of large heavy meals, which can reduce pressure on the stomach and lower reflux chances.
• Avoid eating right before bedtime – Leave at least a 2–3 hour gap between your last meal and sleep to prevent nighttime acidity.
• Plan a light breakfast that’s low in fat and spice to start the day gently on your stomach.
• Include gut-friendly snacks like boiled vegetables, bananas, curd, or soaked almonds between meals to reduce acidity.
• Do not lie down immediately after meals – Stay upright or walk for a few minutes to help with digestion.

 Diet Tips for Better Digestive Health During Veloz D Use

• Include high-fibre foods like oats, whole grains, fruits (banana, papaya), and vegetables to support healthy digestion.
• Avoid spicy, greasy, or fried foods, which may irritate the stomach lining and reduce Veloz D's benefits.
• Limit citrus fruits and tomato-based foods, as they may trigger acid reflux in some individuals.
• Cut down on caffeine and carbonated beverages like coffee, tea, and soft drinks, which can increase stomach acid.
• Stay hydrated with at least 6–8 glasses of water daily, unless otherwise advised by your doctor.
• Choose easily digestible foods such as steamed vegetables, khichdi, curd rice, or plain toast, especially during flare-ups.
• Moderate your intake of chocolate and mint, both known to relax the lower esophageal sphincter and worsen reflux.
• Add probiotics like yogurt or buttermilk to support gut flora and enhance digestive balance.
• Avoid alcohol and smoking, both of which reduce the effectiveness of acid-reducing medications.

1. Is Veloz D Better Suited for Bloating than Omez D?

2. Is Veloz D More Suitable for Reflux Symptoms than Esomeprazole Combinations?

3. Which Capsule Offers Better Digestive Comfort: Veloz D or Razo D?

Drug - Drug interaction

1. Antifungal Medicines (e.g., Ketoconazole, Itraconazole)

Interaction: These medicines require stomach acid for absorption. Rabeprazole reduces stomach acid, which can lower the effectiveness of antifungals.
Management: Your doctor may advise spacing the antifungal and Veloz D capsule apart or consider alternative antifungals that are less affected by stomach pH.

2. Antibiotics (e.g., Clarithromycin, Erythromycin)

Interaction: When used with Domperidone, these antibiotics may increase the risk of irregular heart rhythm (QT prolongation).
Management: A cardiac risk assessment may be done before prescribing. If needed, your doctor might suggest an alternative antibiotic.

3. Anti-HIV Medicines (e.g., Atazanavir, Ritonavir)

Interaction: Rabeprazole can reduce absorption of certain antiretrovirals, decreasing their effectiveness.
Management: These medicines may not be used together. Your doctor may choose a different acid-reducing agent or adjust the HIV treatment plan.

4. Antiplatelet Drug (e.g., Clopidogrel)

Interaction: Rabeprazole may slightly reduce the activation of clopidogrel, potentially lowering its antiplatelet effect.
Management: Though the effect is mild, your doctor may monitor you closely or consider switching to a different acid-reducing therapy if necessary.

5. Central Nervous System Drugs (e.g., Levodopa, Diazepam)

Interaction: Domperidone may affect the levels of certain CNS-active drugs, altering their effects.
Management: Dose adjustments and regular monitoring may be needed if you're taking such medications concurrently.

6. Antacids and Sucralfate

Interaction: These can interfere with the absorption of Rabeprazole if taken together.
Management: Maintain at least a 2-hour gap between Veloz D and antacid/sucralfate intake to ensure proper absorption.

7. Warfarin (Blood Thinner)

Interaction: Co-administration may affect blood clotting parameters, increasing bleeding risk.
Management: Regular INR monitoring is recommended. Your doctor may adjust the warfarin dose based on test results.

8. Digoxin (Heart Medicine)

Interaction: Domperidone may increase digoxin levels, potentially leading to toxicity.
Management: Digoxin levels should be monitored periodically. Dose adjustments may be required under medical supervision.

Drug - Food interaction

1. High-Fat Meals

Interaction: Fat-rich meals may delay gastric emptying, which can reduce the effectiveness of Domperidone’s prokinetic action and slow the onset of Rabeprazole’s effect.
Management: Take Veloz D Capsule before food (preferably 15–30 minutes before a meal) to support timely absorption and proper digestive action.

2. Acidic Beverages (e.g., Citrus Juices, Soft Drinks)

Interaction: Acidic drinks may irritate the stomach lining and counteract the acid-reducing action of Rabeprazole, possibly worsening symptoms of acidity or reflux.
Management: Limit intake of citrus-based and carbonated beverages during Veloz D therapy. Choose neutral or low-acid drinks like water, coconut water, or non-citrus juices.

3. Caffeine-Containing Drinks (e.g., Coffee, Tea, Cola)

Interaction: Caffeine may stimulate gastric acid secretion, which can reduce the effectiveness of Rabeprazole in controlling acidity.
Management: Reduce or moderate intake of caffeine while on this medication to avoid stomach discomfort or breakthrough acidity.

4. Alcohol

Interaction: Alcohol can irritate the stomach lining and interfere with the protective effects of Rabeprazole, potentially increasing side effects like nausea, acid reflux, or dizziness (from Domperidone).
Management: It's best to avoid or limit alcohol during the course of treatment. Discuss with your doctor if occasional consumption is planned.

5. Grapefruit or Grapefruit Juice

Interaction: Grapefruit may affect how Domperidone is processed in the liver, potentially increasing its concentration and risk of side effects like heart rhythm changes.
Management: Avoid grapefruit products while taking Veloz D unless advised otherwise by your healthcare provider.

6. Spicy and Oily Foods

Interaction: These may worsen symptoms of bloating, gas, or acid reflux, potentially reducing the comfort level even while on medication.
Management: Follow a light, non-spicy, low-oil diet to complement the effect of Veloz D and promote better digestive comfort.

Synopsis

More Information

FAQs About VELOZ D CAPSULE

References

1. KD. Tripathi. Antiemetic, Prokinetic and Digestant drugs & Drugs for Peptic Ulcer and Gastroesophageal Reflux Disease. Essentials of medical pharmacology. Seventh edition. 2013. Page-666 & 651-653.

2. Keith A. Sharkey and John L. Wallace. Treatment of disorders of bowel motility and water flux; Antiemetics; Agents used in biliary and pancreatic disease and Pharmacotherapy of gastric acidity, peptic ulcer and gastroesophageal reflux disease. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page-1326 & 1317-1320.

3. Gerald G. Briggs and Roger K. Freeman. D. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page-1232 & -3337.

4. Janssen Research & Development, LLC. A Pharmacokinetics, Pharmacodynamics and Safety Study of Rabeprazole in Newborn Infants with Gastroesophageal Reflux Disease (GERD). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in April 2013] [Accessed on 21st July 2025]

5. Savita Shahani, Prabha Sawant, Preen Dabholkar. Rabeprazole plus domperidone: the answer for gastro-esophageal reflux disease. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. April 2008. [Accessed on 21st July 2025]

6. K Semmanaselvan, Qayum I Mukaddam, Manoj Naik. An Open Label, Prospective, Single Centre Study to Evaluate the Efficacy and Safety of Fixed Dose Combination of Rabeprazole (Enteric-Coated, EC) 20 mg + Domperidone (Sustained Release, SR) 30 mg Capsule in Treatment of Patients with Laryngopharyngeal Reflux Disease. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. July 2015. [Accessed on 21st July 2025]

7. Cipla Ltd. Rabicip D Capsules (Rabeprazole sodium + Domperidone). Ciplamed.com. [Revised in January 2020] [Accessed on 21st July 2025]

Useful Diagnostic Tests

• Complete Blood Count (CBC)
• Stool Complete Analysis

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Vrushabhakumar Jitendra Shah. - MBBS

Last updated on 21 Jul 2025 | 12:15 PM(IST)