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Ikon Remedies Pvt Ltd

VANCOBEST 500mg Injection 1's

Bacterial Infections
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    Introduction About VANCOBEST 500MG INJECTION

    VANCOBEST 500MG INJECTION contains Vancomycin which belongs to the group of medicines called Glycopeptide antibiotics. It is used for the management of serious infections caused by susceptible strains of methicillin-resistant (beta-lactam-resistant) staphylococci bacteria.

    VANCOBEST 500MG INJECTION is used for the management of endocarditis (infection to the inner lining of heart with symptoms of fever, chills, difficulty in breathing etc) as well as is used for the management of hospital acquired pneumonia, infections of skin and tissues below skin, bone and joints (involves osteomyelitis, arthritis, spinal infections etc with symptoms of pain, fever, chills, swelling in joints etc).

    Also, it is used to manage central nervous system infection (meningitis, abscess, brain enlargement with symptoms of headache, fever, mood changes) and blood caused by bacteria. Symptoms of these infections are usually recurrent fever and chills, headache and difficulty in breathing. VANCOBEST 500MG INJECTION is also used to manage infections in patients who are allergic to the medicines containing penicillin and cephalosporins.

    Before receiving VANCOBEST 500MG INJECTION, your doctor will do few blood tests to determine the exact cause of infection. It should be used only to manage infections that are proven or strongly suspected to be caused by susceptible bacteria.

    VANCOBEST 500MG INJECTION is not recommended in patients who have hypersensitivity to vancomycin.

    Before receiving VANCOBEST 500MG INJECTION inform your doctor if you have kidney diseases or hearing diseases. VANCOBEST 500MG INJECTION should be used in caution in pregnant and breast-feeding women. Consult your doctor before receiving it.

    The common side effects of receiving VANCOBEST 500MG INJECTION include difficulty in breathing, fall in blood pressure, redness of body and face, fever, etc. Contact your physician if any of the symptoms worsen with time.

    Uses Of VANCOBEST 500MG INJECTION

    Used in adults and children: 

    • To manage endocarditis (infection to the inner lining of heart with symptoms of fever, chills, difficulty in breathing)
    • Manage serious or severe infections caused by susceptible strains of methicillin-resistant (beta-lactam-resistant) staphylococci
    • Manage hospital acquired pneumonia (infection of the lungs that makes airspaces to be filled with fluid or pus with the symptoms of fever and chills, cough with phlegm or pus, headache, difficulty in breathing, tiredness)
    • Manage infections of the skin
    • Manage infections of bone and joint (includes osteomyelitis, arthritis, spinal infections etc with symptoms of pain in bones, fever with chills, swelling in joints, pain at the site)
    • Manage infections of central nervous system (such as meningitis (infection of brain), abscess, brain enlargement)

    How VANCOBEST 500MG INJECTION Works

    VANCOBEST 500MG INJECTION is a glycopeptide antibiotic that works by managing cell wall formation of infection causing bacteria by blocking the enzymes responsible for it.

    How to use VANCOBEST 500MG INJECTION

    VANCOBEST 500MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.  

    Side Effects Of VANCOBEST 500MG INJECTION

    Common

    • fall in blood pressure
    • difficulty in breathing
    • swelling at injection site (thrombophlebitis)
    • skin rashes with fever
    • redness in face and body
    • chest pain
    • back pain
    • whistling sound while breathing
    • hives  
    • itching in skin
    • kidney diseases
    • mucosal inflammation

    Uncommon

    • temporary or permanent hearing loss

    Rare

    • dizziness
    • fever with chills
    • nausea
    • loose stools
    • ringing sound in ears
    • spinning of head
    • inflammation of blood vessels
    • nausea
    • anaphylactic reactions

    Stop receiving VANCOBEST 500MG INJECTION and contact your doctor if you experience any of the following side effects:  

    • skin rashes, swelling of the face, lips, tongue or throat, difficulty breathing or swallowing, dizziness
    • cardiac arrest (loss of consciousness breathing and heart function)
    • skin with rashes, blisters, pain along with fever
    • occurrence of areas with redness and swelling on body along with fever (skin condition called acute generalized exanthematous pustulosis)
    • painful red area without blister formation which spreads quickly and causes skin to peel associated with fever, chills (toxic epidermal necrolysis)
    • occurrence of diarrhoea which may be severe or continues for a long time during (it may be a sign of bowel inflammation)

    How To Manage Side Effects

    Swelling at injection site:

    Do not massage the affected area. Apply ice packs or cold packs at the site. Inform your doctor if the symptom does not improve. 

    Nausea:

    Avoid eating fried and greasy food. Take simple, light, small meals at frequent intervals. Drink plenty of fluids and stay hydrated always. Inform your doctor if the symptom does not improve.

    Diarrhoea:

    Drink plenty of water, fluids and electrolytes such as ORS and stay hydrated. Inform your doctor if the symptom does not improve.

    Headache:

    Drink plenty of fluids and stay hydrated. Try to be tension free and relaxed. Take adequate sleep and rest. Avoid consumption of alcohol. Apply pain balm if required. Inform your doctor if the symptom does not improve. 

    Warning & Precautions

    Pregnancy

    VANCOBEST 500MG INJECTION should be given during pregnancy only if considered clearly necessary. Consult your doctor before receiving it.            

    Breastfeeding

    VANCOBEST 500MG INJECTION should be given during breast-feeding only if considered clearly necessary as it may pass through the breast milk. Consult your doctor before receiving it.     

    Driving and Using Machines

    VANCOBEST 500MG INJECTION has no or negligible effect on your ability to drive and use machines.  

    Kidney

    VANCOBEST 500MG INJECTION should be used with caution in patients with kidney disorder. Consult your doctor before receiving it.    

    Allergy

    Do not receive VANCOBEST 500MG INJECTION if you are allergic to vancomycin or any other ingredients of this medicine.  

    Others

    Before receiving VANCOBEST 500MG INJECTION, inform your doctor if you:

    • have hearing disorder
    • blood disorders
    • sensitive to any food or medicine

    Use in pediatrics:

    VANCOBEST 500MG INJECTION should be used with caution in with particular care in premature infants and young infants, because their kidneys are not fully developed and they may accumulate VANCOBEST 500MG INJECTION in the blood. This age group may need blood tests for controlling vancomycin levels in blood. Consult your child’s doctor for advice.

    Use in geriatrics:

    VANCOBEST 500MG INJECTION is used with caution in elderly people with kidney diseases, hearing diseases and those who are undergoing dialysis. Your doctor will do blood test and hearing test during management with VANCOBEST 500MG INJECTION. Lower dose of VANCOBEST 500MG INJECTION is advised for elder people. Consult your doctor before receiving it.

    Interactions

    A. Drug–Drug interactions:

     Before taking VANCOBEST 500MG INJECTION inform your doctor if you are receiving the following medicines:    

    • medicines used to manage infections (Ex. antibiotics like streptomycin, gentamycin, amikacin, bacitracin, piperacillin, tazobactam)
    • medicines used for managing tuberculosis (Ex. viomycin)
    • medicines used to relieve pain (Ex. Propofol, ketamine, Ibuprofen)
    • medicines used to manage cancer (Ex. cisplatin)
    • medicines used to manage fungal infection (Ex. Amphotericin B)  
    • medicines for muscle relaxation during anesthesia (Ex. atracurium, mivacurium)

    Overdosage:

    VANCOBEST 500MG INJECTION will be administered to you only by a doctor or a nurse in a hospital and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.

    Synopsis

    Drug :   Vancomycin
    Pharmacological Category :   Glycopeptides
    Therapeutic Indication :   Used to manage endocarditis, pneumonia infections of the skin, infections of bone and joints, infections of central nervous system          
    Dosage Forms :   Tablet, Capsule, Injection

    More Information

    • Store at room temperature

     

    FAQs About VANCOBEST 500MG INJECTION

    What is VANCOBEST 500MG INJECTION used for?

    VANCOBEST 500MG INJECTION is used for the management of management of serious or severe infections caused by susceptible strains of methicillin-resistant (beta-lactam-resistant) staphylococci, endocarditis (inflammation of interlining of heart). It is also used for the management of pneumonia, infections in the skin, infections of bone and joints (like osteomyelitis, arthritis) and for infections in the central nervous system (ex. Meningitis, abscess). Consult your doctor before receiving it.

    How to use VANCOBEST 500MG INJECTION?

    VANCOBEST 500MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Consult your doctor before receiving it.

    Can I receive VANCOBEST 500MG INJECTION during breast feeding?

    VANCOBEST 500MG INJECTION is not recommended if you are breastfeeding since the active ingredients may pass through the breast milk. Consult your doctor before receiving it.

    What all precautions to be taken before receiving VANCOBEST 500MG INJECTION?

    Before receiving VANCOBEST 500MG INJECTION inform your doctor if you are suffering from hearing disturbances, kidney diseases or you are aged above 65 years. Do not use VANCOBEST 500MG INJECTION if you are allergic to vancomycin. Consult your doctor before receiving it.

    Which all medicines to be avoided while receiving VANCOBEST 500MG INJECTION?

    Before receiving VANCOBEST 500MG INJECTION inform your doctor if you are taking any other medicines for the management of bacterial infections (such as spiramycin, amikacin), fungal infections (Ex. Amphotericin B) tuberculosis (Ex. viomycin), cancer (Ex. Cisplatin), relieve pain (Ex. Ketamine) to avoid unwanted side effects.

    References

    1. KD Tripathi. Autocoids and related drugs. Essentials of Medical Pharmacology.8th edition. 2019. Page – 806-807.

    2. Shivali Patel; Charles V. Preuss; Fidelia Bernice.Vancomycin. Patel, Shivali, Charles V. Preuss, and Fidelia Bernice. Vancomycin. National library of Medicine, National center for Biotechnology information. Pubmed Central. March 2022 [Accessed on 29th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK459263/

    3. Sofarimex. Electronic Medicines Compodium (EMC) [Revised in August 2008] [Accessed on 29th July 2022] https://www.medicines.org.uk/emc/files/pil.8759.pdf

    4. Wockhardt UK Limited. Electronic Medicines Compodium (EMC). [Revised in December 2020] [Accessed on 29th July 2022] https://www.medicines.org.uk/emc/files/pil.6255.pdf

    5. Vancomycin. Ciplamed. [Revised in December 2020] [Accessed on 29th July 2022] https://www.ciplamed.com/https%3A//ciplamed.com/content/vanlid-injection-0

    Useful Diagnostic Tests

    • Antibiotic sensitivity tests
    • Complete blood count  

    Author Details

    Written By Dr. R. Dinesh John Rajkumar - Pharm.D
    Reviewed For Accuracy By Dr. Salem Gill - MBBS
    Last updated on 28 Nov 2022 | 10:21 AM(IST)
    Lab updated