VALERA Tablet 15's

Introduction About VALERA TABLET

VALERA TABLET contains Evogliptin which belongs to the group of medicines called Anti-diabetic agents. It is used to manage type 2 diabetes mellitus as an adjunct to diet and exercise to improve glycaemic control, when used as a monotherapy or in combination with metformin.

VALERA TABLET is not recommended for severe ketosis, diabetic come or pre-coma or type 1 diabetes. Before taking VALERA TABLET inform your doctor if you have any liver, kidney, heart problems or history of pancreatitis. VALERA TABLET is not recommended for pregnant and breastfeeding women. Consult your doctor before taking the medicine.

The most common side effects of taking VALERA TABLET are hypoglycemia, stomach pain, indigestion, common cold, pain, diarrhoea and itching. Consult your doctor if any of the above side effects worsens or persists for a longer duration.

Uses Of VALERA TABLET

• It is used for type 2 diabetes mellitus as an adjunct to diet and exercise to improve glycaemic control, when used as a monotherapy or in combination with metformin

How VALERA TABLET Works

Glucagon-like peptide-1 (GLP-1) is secreted from alimentary canal in response to meal that promotes insulin secretion from pancreas and regulates blood sugar post meal by controlling glucagon secretion. VALERA TABLET exhibits a hypoglycemic effect by controlling the decomposition of GLP-1 by inhibiting dipeptidyl peptidase-4 (DPP-4) activity and thereby increasing blood concentration of active form GLP-1.

How to use VALERA TABLET

Take VALERA TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration depending upon your age, body weight and disease condition.

Side Effects Of VALERA TABLET

How To Manage Side Effects

Hypoglycemia

Eat or drink 15 to 20 grams of fast-acting carbohydrates. These are sugary foods or drinks without protein or fat that are easily converted to sugar in the body. Have a snack or meal.

Stomach Pain

Try putting a heating pad or hot towel on your abdomen. The heat can help relax the muscles and relieve cramping. Taking a hot shower or bath with salt may also help. 

Warning & Precautions

Pregnancy

Contraindicated

VALERA TABLET is not recommended for use in pregnant women. Consult your doctor before taking the medicine.

Breastfeeding

Contraindicated

VALERA TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking the medicine.

Driving and Using Machines

Use with Caution

Do not drive or operate any heavy tools or machines if you experience hypoglycemia after taking VALERA TABLET.

Kidney

Consult your doctor

VALERA TABLET is not recommended for patients with end stage renal impairment requiring dialysis. It should be used with caution in patients with moderate to severe renal impairment. Consult your doctor for advice.

Liver

Use with Caution

VALERA TABLET should be used with caution in patients with mild to moderate hepatic impairment. Consult your doctor before taking the medicine.

Allergy

Contraindicated

Do not take VALERA TABLET if you are allergic or hypersensitive to Evogliptin or any other ingredients of this medicine.

Heart Disease

Consult your doctor

VALERA TABLET is not recommended to patients with functional class II-IV due to absence of clinical experience. It should be used with caution in patients with functional class 1 heart failure. Consult your doctor for advice.

Use In Pediatrics

Consult your doctor

Safety and efficacy in children have not been established. Consult your doctor for advice.

Use In Geriatrics

Use with Caution

VALERA TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor for advice before taking the medicine.

Interactions

A. Drug - Drug interactions:

Before taking VALERA TABLET, inform your doctor if you are taking any of the following medicines:

• other medicines used for diabetes mellitus (such as insulin or metformin)
• clarithromycin, rifampicin (used to manage infection)

Overdosage:

If you or anyone else accidentally took more VALERA TABLET consult your doctor immediately or nearby hospital.

Synopsis

More Information

• Keep VALERA TABLET out of reach of children
• Store VALERA TABLET at room temperature

FAQs About VALERA TABLET

Q: What is VALERA TABLET used for?

A: It is used to manage type 2 diabetes mellitus as an adjunct to diet and exercise to improve glycaemic control, when used as a monotherapy or in combination with metformin.

Q: How and when to take VALERA TABLET?

A: Take VALERA TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration depending upon your age, body weight and disease condition.

Q: What to do if I forgot to take a dose of VALERA TABLET?

A: If you forgot to take a dose of VALERA TABLET, take it as soon as you remember. However, if it is time for the next dose of VALERA TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of VALERA TABLET to compensate the missed ones.

Q: Can I stop taking VALERA TABLET without consulting the doctor?

A: No. You should not stop taking VALERA TABLET without consulting the doctor because it may cause some side effects.

Q: Will taking a higher dose of VALERA TABLET be more effective?

A: No, taking a higher dose of VALERA TABLET will not be effective. Always stick to the dose and duration prescribed by your doctor.

Q: What precautions do I need to follow while taking VALERA TABLET?

A: VALERA TABLET is not recommended for severe ketosis, diabetic come or pre-coma or type 1 diabetes. Before taking VALERA TABLET inform your doctor if you have any liver, kidney, heart problems, and history of pancreatitis.

Q: Can VALERA TABLET be used in pregnant women?

A: VALERA TABLET is not recommended for use in pregnant women. Therefore, consult your doctor for advice before taking it.

Q: How much VALERA TABLET should I take?

A: VALERA TABLET should be used only under medical supervision. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body condition and severity of the disease condition.

Q: Is it safe to use VALERA TABLET in patients with heart problems?

A: VALERA TABLET is not recommended to patients with functional class II-IV due to absence of clinical experience. It should be used with caution in patients with functional class 1 heart failure. Consult your doctor for advice.

Q: Is it safe to use VALERA TABLET on elderly patients?

A: VALERA TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor for advice before taking the medicine.

References

1. KD. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 270.

2. Xueying Tan and Jingbo Hu. Evogliptin: a new dipeptidyl peptidase inhibitor for the treatment of type 2 diabetes. National library of medicine. June 2016. [Accessed on December 22nd, 2023] https://pubmed.ncbi.nlm.nih.gov/27156529/

3. Alkem Laboratories Ltd. [Revised on April 21st, 2020] [Accessed on December 22nd, 2023] https://www.alkemlabs.com/pdf/adverse/Evogliptin.pdf

4. Geropharm. [Accessed on December 22nd, 2023] https://geropharm.com/portfolio/endokrinologiya/evodin-evogliptin

Useful Diagnostic Tests

• HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
• Blood Glucose Fasting (FBS)
• Post Prandial Blood Sugar (PPBS)
• Insulin - Fasting
• Netmeds Diabetic Checkup
• Advance Diabetes Monitoring (Senior Female)
• Jaanch Diabetic Profile Basic

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)

Last updated on 28 Dec 2023 | 11:45 AM(IST)