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Introduction About UDZIRE 100MG TABLET
UDZIRE 100MG TABLET contains Udenafil, which belongs to the group of medicines called Phosphodiesterase type 5 (PDE5) inhibitors. It is used in adult men to improve blood flow to the penis.
UDZIRE 100MG TABLET is not recommended for use in patients with severe liver or kidney disease, low or uncontrolled high blood pressure, severe heart disease, or stroke. Consult your doctor before taking it.
UDZIRE 100MG TABLET is not recommended for use in pregnant and breastfeeding women or in children under 18 years of age, and UDZIRE 100MG TABLET should be used with caution in elderly patients above 65 years of age. Contact your doctor before taking it.
The most common side effects of taking UDZIRE 100MG TABLET are flushing and headache. Consult your doctor if any of the symptoms worsen.
Uses Of UDZIRE 100MG TABLET
- To improve blood flow to the penis
How UDZIRE 100MG TABLET Works
UDZIRE 100MG TABLET blocks the phosphodiesterase enzyme in the body and releases a chemical called nitric oxide, which helps to relax the smooth muscles and blood vessels supplying the inner part of the penis. This increases the supply of blood to the penis.
How to use UDZIRE 100MG TABLET
Always take UDZIRE 100MG TABLET as directed by your physician. Swallow the medicine with a glass of water, and do not crush or chew the medicine. Your doctor will decide the correct dose, duration, and frequency for you depending on your age, body weight, and other comorbid conditions, etc.
Side Effects Of UDZIRE 100MG TABLET
Common
- flushing
- headache
Stop taking UDZIRE 100MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- sign of non-arteritic anterior ischemic optic neuropathy (NAION), such as sudden loss of vision in one or both eyes
- sudden hearing loss or deafness, which may be accompanied by tinnitus and dizziness, in one or both ears
How To Manage Side Effects
Headache
Rest and relax. Drink plenty of fluids, such as water or ORS (Oral Rehydrating Solution) and apply a pain-relieving balm to the head if necessary. Contact your doctor if your headache does not improve.
Warning & Precautions
Pregnancy
ContraindicatedUDZIRE 100MG TABLET is not recommended for use by pregnant women. Consult your doctor before taking it.
Breastfeeding
ContraindicatedUDZIRE 100MG TABLET is not recommended for use by breastfeeding mothers. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionUDZIRE 100MG TABLET may cause dizziness and blurred vision. Do not drive or operate any machines.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking UDZIRE 100MG TABLET, as it may cause side effects such as increased heart rate, decreased blood pressure, dizziness, muscle pains, and orthostatic syndrome. Consult your doctor before taking it.
Kidney
ContraindicatedUDZIRE 100MG TABLET is not recommended for use in patients with severe kidney disease. Consult your doctor before taking it.
Liver
ContraindicatedUDZIRE 100MG TABLET is not recommended for use in patients with severe liver disease. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take UDZIRE 100MG TABLET if you are allergic to Udenafil or to any other ingredients in this medicine.
Heart Disease
Consult your doctorUDZIRE 100MG TABLET is not recommended for use in patients with low blood pressure or uncontrolled high blood pressure, severe heart disease such as cardiac failure, unstable angina pectoris (chest pain), or myocardial infarction (heart attack). Consult your doctor before taking it.
UDZIRE 100MG TABLET should be used with caution in patients with aortic stenosis (narrowing of a blood vessel in the heart) and hypertrophic obstructive cardiomyopathy (thickening of heart muscle). Consult your doctor before taking it.
Use In Pediatrics
ContraindicatedUDZIRE 100MG TABLET is not recommended for use in children and adolescents under 18 years of age. Consult your doctor before taking it.
Use In Geriatrics
Use with CautionUDZIRE 100MG TABLET should be used with caution in elderly patients over 65 years of age. Contact your doctor before taking it.
Others
UDZIRE 100MG TABLET is not recommended for use if you:
- recently had a stroke
- have non-arteritic anterior ischemic optic neuropathy (decreased blood supply to the eye)
- have eye disorders such as retinitis pigmentosa
- have genetic problems such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption
Before taking UDZIRE 100MG TABLET, inform your physician if you:
- have an anatomical deformation of the penis (such as angulation, cavernosal fibrosis, or Peyronie's disease)
- have sickle cell anemia (red blood cell disorder)
- have multiple myeloma or leukemia (a type of blood cancer)
Interactions
A. Drug-Drug interactions:
Before taking UDZIRE 100MG TABLET, inform your doctor if you are taking any of the following medicines:
- ketoconazole and itraconazole (used to manage fungal infections)
- ritonavir and indinavir (used to manage viral infections)
- erythromycin (used to manage bacterial infections)
- cimetidine (used to manage stomach ulcers)
- carbamazepine, phenytoin, and phenobarbital (used to manage fits or seizures)
- nitroglycerine (used to manage heart disease)
- captopril and enalapril (used to manage high blood pressure)
- dexamethasone (used to manage inflammatory conditions)
- rifampin (used to manage tuberculosis)
- riociguat (used to manage pulmonary hypertension)
- glyceryl trinitrate, isosorbide mononitrate, sodium nitroprusside, amyl nitrite, and nicorandil (used to manage chest pain and high blood pressure)
- tamsulosin (used to manage benign prostate hyperplasia)
B. Drug-Food interaction:
Avoid consuming grapefruit juice while taking UDZIRE 100MG TABLET. Consult your doctor for advice.
Overdosage:
If you or anyone else accidentally took more of UDZIRE 100MG TABLET, contact your doctor immediately or visit a nearby hospital immediately if the symptoms worsen. Symptoms of an overdose include headache and flushing.
Synopsis
| Drug | : | Udenafil |
| Pharmacological Category | : | Phosphodiesterase type 5 (PDE5) inhibitors |
| Therapeutic Indication | : | Erectile dysfunction |
| Dosage Forms | : | Tablet |
More Information
- Keep UDZIRE 100MG TABLET out of reach of children
- Store UDZIRE 100MG TABLET below 30°C
FAQs About UDZIRE 100MG TABLET
Q: Is UDZIRE 100MG TABLET safe in pregnancy?
A: No. UDZIRE 100MG TABLET is not recommended for use in pregnant women. Inform your doctor if you are pregnant or planning to be pregnant before taking this medicine.
Q: What are the side effects of taking UDZIRE 100MG TABLET?
A: The side effects of taking UDZIRE 100MG TABLET are headache, dizziness, eye pain, flushing, and congestion. Consult your doctor if you experience any side effects after taking this medicine.
Q: How do I use UDZIRE 100MG TABLET?
A: Take UDZIRE 100MG TABLET as directed by your physician. It should be taken approximately 30 minutes to 12 hours before sexual activity. Swallow the medicine with a glass of water, and do not crush or chew the medicine. Your doctor will decide the correct dose, duration, and frequency for you depending on your age, body weight, and other comorbid conditions, etc.
Q: Who should not take UDZIRE 100MG TABLET?
A: UDZIRE 100MG TABLET is not recommended for use in patients with severe liver, kidney disease, low blood pressure or uncontrolled high blood pressure, severe heart disease such as cardiac failure and unstable angina pectoris (chest pain), myocardial infarction (heart attack), stroke, non-arteritic anterior ischemic optic neuropathy (decreased blood supply to the eye), or eye disorders such as retinitis pigmentosa and genetic problems such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption. Consult your doctor before taking it.
References
1. Longo, Fauci, Kasper, Hauser, Jameson, and Loscalzo. Endocrinology and Metabolism. Harrison’s Manual of Medicine. 18th Edition. 2013. Page – 1148.
2. Sung Gu Kang and Je Jong Kim. Udenafil: efficacy and tolerability in the management of erectile dysfunction. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. [Revised in April 2013] [Accessed on 8th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607490/
3. Min Chul Cho and Jae-Seung Paick. Udenafil for the treatment of erectile dysfunction. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. [Revised in May 2014] [Accessed on 8th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027935/
4. Dong-A ST Co., Ltd. Udenafil. [Revised in September 2017] [Accessed on 8th July 2022] https://quest3plus.bpfk.gov.my/front-end/attachment/627/pharma/211259/V_3772_20170913_065537_D3.pdf
5. Udzire (Udenafil). Lotus International. [Accessed on 8th July 2022] https://lotusinternational.com/product/udzire/
6. Udenafil. Taj Pharma India. [Accessed on 8th July 2022] https://tajpharma.in/portfolio-item/udenafil-tablets-100mg/
7. MIMS. Udenafil. [Accessed on 8th July 2022] https://www.mims.com/malaysia/drug/info/zydena?type=full
8. Drug Bank. Udenafil. [Revised in June 2021] [Accessed on 8th July 2022] https://go.drugbank.com/drugs/DB06267
Useful Diagnostic Tests
- Prostate Specific Antigen - Psa (Total)
- Prostate Specific Antigen - Psa (Free)
- Complete Blood Count (CBC)/Hemogram
- Testosterone
- Testosterone Free
- Dht Di Hydro Testosterone
- 5-A Dihydrotestosterone
- Urine Routine and Microscopy
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