Udiliv 75mg Tablet 10'S
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INTRODUCTION ABOUT UDILIV 75MG TABLET
UDILIV 75MG TABLET contains Ursodeoxycholic Acid, which is a liver health supplement. It is used to manage primary biliary cirrhosis (damage of bile ducts in the liver leading to the buildup of bile).
UDILIV 75MG TABLET is also used to dissolve small gallstones that are not visible on X-rays (less than 15 mm in diameter) in patients with a functioning gall bladder. Gall stones are hardened deposits mostly made up of cholesterol that can form in the gallbladder and can cause sharp, intense pain in the upper right part of the abdomen.
UDILIV 75MG TABLET can also be used for liver disease associated with cystic fibrosis in children aged 6 to less than 18 years. Cystic fibrosis is a disease that affects the cells that produce mucus, sweat, and digestive juices and causes these fluids to become thick and sticky, resulting in plugged-up tubes, ducts, and passageways.
During or while the management with UDILIV 75MG TABLET, your doctor might ask you to get several diagnostic tests done, such as a liver function test and a gall bladder scan.
UDILIV 75MG TABLET is not recommended for use in patients with allergies to bile acids, calcified gallstones, inflammation of the gallbladder or the bile ducts, blockage of the common bile duct or cystic duct, frequent cramp-like pains in the upper abdomen, low bile flow in children, or improper function of the gall bladder. UDILIV 75MG TABLET should be used with caution in patients with liver diseases.
UDILIV 75MG TABLET should be taken during pregnancy only if clearly advised by the doctor and should be used with caution in breast-feeding women. Ask for your doctor’s advice before taking. UDILIV 75MG TABLET can be used in children, adolescents, and the elderly. Your doctor will decide the correct dose and duration of therapy with UDILIV 75MG TABLET for you.
The most common side effects of taking UDILIV 75MG TABLET are soft, loose stools or diarrhea. Consult your doctor if the symptoms worsen or don’t improve.
USES OF UDILIV 75MG TABLET
Used to manage:
- Primary biliary cirrhosis (PBC)
- Gallstones (not visible on X-rays in patients with a functioning gall bladder)
- Liver disease associated with cystic fibrosis in children aged 6 to 18 years
HOW UDILIV 75MG TABLET WORKS
UDILIV 75MG TABLET supports liver detoxification by increasing the bile flow through the liver and protects liver cells. UDILIV 75MG TABLET is concentrated in bile and decreases biliary cholesterol by suppressing the formation of new cholesterol by inhibiting its intestinal absorption. The reduced cholesterol levels lead to gradually solubilization of cholesterol from gallstones, resulting in their dissolution.
DIRECTIONS FOR USE
Always use UDILIV 75MG TABLET exactly as prescribed by your doctor. Take this medicine with or after meals.
For Tablet, Capsule: Swallow the medicine with a glass of water or milk. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse the medicine in the specified quantity of water as mentioned in the label. Consume the mixture immediately after reconstitution.
Your doctor will decide the right dose and duration of Tab UDILIV for you depending upon your age, body weight and severity of disease condition. Continue to take Tab UDILIV for the stipulated duration prescribed by your doctor to achieve better results. If you feel that the effect of Tab UDILIV is too strong or too weak for you, please talk to your doctor.
SIDE EFFECTS OF UDILIV 75MG TABLET
COMMON
- Soft, loose stools
- Diarrhoea
Stop taking Tab UDILIV and contact your doctor immediately if you experience any of the following side effects:
- Persistent diarrhoea
HOW TO MANAGE SIDE EFFECTS
Diarrhea
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. Ask for your doctor’s advice if diarrhoea doesn’t improve.
WARNING & PRECAUTIONS
PREGNANCY
Consult your doctorUDILIV 75MG TABLET should be used in pregnant women only if considered clearly necessary by the doctor. If you are pregnant or think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking UDILIV 75MG TABLET.
BREASTFEEDING
Use with CautionUDILIV 75MG TABLET should be used with caution in breastfeeding women as it is not known if it passes through breast milk. Consult your doctor if you are breastfeeding or about to start breastfeeding before taking UDILIV 75MG TABLET.
DRIVING AND USING MACHINES
SafeUDILIV 75MG TABLET has no or negligible effect on driving or using machine.
LIVER
Use with CautionUDILIV 75MG TABLET should be used with caution in patients with liver diseases. Your doctor might advise you for frequent liver examination and tests during the> management. Consult your doctor before taking the UDILIV 75MG TABLET.
ALLERGY
ContraindicatedDo not take UDILIV 75MG TABLET if you are allergic to allergic to Ursodeoxycholic Acid or bile acids or any other components of this medicine.
USE IN PEDIATRICS
Consult your doctorUDILIV 75MG TABLET is not recommended for use in children with biliary atresia (blockage in bile duct) and who have poor bile flow, even after surgery. It can be used in other children. Your doctor will decide the correct dose and duration of UDILIV 75MG TABLET for your child depending on his weight, age, and diseases condition. Consult with your child’s doctor before giving it to your child.
USE IN GERIATRICS
Consult your doctorUDILIV 75MG TABLET can be used in elderly patients. However, consult with your doctor before taking UDILIV 75MG TABLET.
OTHERS
UDILIV 75MG TABLET is not recommended for use if you:
- Have improper functioning of gall bladder
- Have calcified gallstones which are visible on an x-ray
- Have an acute inflammation of the biliary tract or gall bladder
- Have a blockage of the cystic duct or common bile duct (obstruction of the biliary tract)
- Experience frequent cramp-like pains in the upper abdomen
INTERACTIONS
A. Drug-Drug interactions:
Before taking UDILIV 75MG TABLET, inform your doctor if you are taking any of the following medicines:
- Contraceptives (Ex. levonorgestrel, ethinyl estradiol)
- Antacids (Ex. aluminium hydroxide)
- Antilipidemic (Ex. cholestyramine, clofibrate, and colestipol)
- Anti-infective (Ex. ciprofloxacin, dapsone)
- Antihypertensives (Ex. nitrendipine, rosuvastatin)
- Immunosuppressants(Ex. ciclosporin)
Overdosage:
If you or anyone else takes too much of UDILIV 75MG TABLET, consult your doctor immediately or visit the nearby hospital. The symptom of overdosage is diarrhea.
SYNOPSIS
| Drug | : | Ursodeoxycholic Acid |
| Pharmacological Category | : | Cholagogues and Choleretics |
| Therapeutic Indication | : | Biliary cirrhosis, Gallstones, Liver diseases associated with cystic fibrosis |
| Dosage Forms | : | Tablet, Dispersible tablet, Suspension, Syrup |
MORE INFORMATION
STORAGE
- Keep UDILIV 75MG TABLET out of reach of children
- Store UDILIV 75MG TABLET at room temperature below 30°C
FAQs ABOUT UDILIV 75MG TABLET
Q: What is UDILIV 75MG TABLET used for?
A: UDILIV 75MG TABLET is a liver care supplement used for liver detoxification and promotes liver wellness support, liver health restoration, and liver health enhancement.
Q: Why is UDILIV 75MG TABLET prescribed?
A: UDILIV 75MG TABLET is a liver cleanse supplement used in the management of primary biliary cirrhosis (PBC). It can also be used in the dissolution of cholesterol gallstones and to manage liver conditions associated with cystic fibrosis in children aged 6 to 18 years.
Q: Do I need to undergo any diagnostic tests before or while getting managed with UDILIV 75MG TABLET?
A: During or while the management with UDILIV 75MG TABLET, your doctor might ask you to get several diagnostic tests done, such as a liver function test and a gall bladder scan.
Q: Can I stop taking UDILIV 75MG TABLET on my own?
A: Do not stop taking UDILIV 75MG TABLET unless advised by your doctor. Your doctor might advise you on how long you should continue to take UDILIV 75MG TABLET. From time to time, you will need to consult your doctor to review your management and assess your symptoms.
Q: Can UDILIV 75MG TABLET cause diarrhoea?
A: Diarrhoea is the most common side effect of UDILIV 75MG TABLET. It may occur as a result of an overdose as well. If you do suffer from diarrhea, make sure you drink enough liquids to replace your fluid and electrolyte balance and stay hydrated. Stop taking UDILIV 75MG TABLET and inform your doctor immediately if you have persistent diarrhea.
Q: What is the best time to take UDILIV 75MG TABLET?
A: Take UDILIV 75MG TABLET with or after meals. For tablet or capsule, swallow UDILIV 75MG TABLET with a glass of water or milk. Do not crush or chew the medicine. For the dispersible tablet, disperse UDILIV 75MG TABLET in the specified quantity of water as mentioned in the label. Consume the mixture immediately after reconstitution. If you feel that the effect of UDILIV 75MG TABLET is too strong or too weak for you, please talk to your doctor.
Q: What is the role of UDILIV 75MG TABLET in fatty liver?
A: UDILIV 75MG TABLET targets the liver, where it becomes concentrated in the bile produced. Consequently, it inhibits the liver's synthesis and release of cholesterol, resulting in decreased cholesterol levels in the bile. Additionally, it manages the intestines from absorbing bile salts and cholesterol. This dual action lowers cholesterol saturation in bile, facilitating the gradual dissolution of gallstones and reducing their size over time until they completely dissolve. Moreover, by enhancing bile flow through the liver, this medication lowers elevated liver enzyme levels, thus safeguarding liver cells.
Q: When should I take UDILIV 75MG TABLET?
A: Your doctor may advise you to take 2 to 3 doses daily, with the last dose recommended at bedtime. UDILIV 75MG TABLET is best taken with water or milk and can be consumed with or after meals. The appropriate timing for taking this medication may vary based on your specific condition. Ideally, the doses should be spaced at 6-hour intervals, such as at 8 a.m., 2 p.m., and 8 p.m.
Q: Does UDILIV 75MG TABLET cause weight gain?
A: Weight gain may be associated with the use of UDILIV 75MG TABLET, particularly when prescribed for liver disease characterized by chronic bile stasis in the small bile ducts of the liver. In such cases, the normal flow of bile from the liver to the small intestine is hindered. It's important to note that the likelihood of weight gain varies among individuals, depending on the specific disease. If you notice any weight gain, it is advisable to consult your doctor for guidance.
Q: Can we use UDILIV 75MG TABLET for kidney stones?
A: No, UDILIV 75MG TABLET is used for dissolving gallstones and not kidney stones.
Q: Does UDILIV 75MG TABLET cause constipation?
A: Constipation is one of the common side effects of taking this medicine. However, it is usually short-lived and disappears on its own. If this side effect does not resolve on its own, consult your doctor.
Q: Is it safe to buy UDILIV 75MG TABLET from online pharmacies like Netmeds in India?
A: Generally, it is safe to buy UDILIV 75MG TABLET from reputable online pharmacies like Netmeds in India. Netmeds adheres to strict regulations to ensure the quality and authenticity of the medications. Netmeds has made buying online medicines easier for consumers and is one of India's leading online pharmacies.
REFERENCES
1. KD. Tripathi. Antiemetic, Prokinetic and Digestant drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page - 671.
2. Jelena S Rudic, Goran Poropat, Miodrag N Krstic, Goran Bjelakovic, Christian Gluud, Cochrane Hepato-Biliary Group. Ursodeoxycholic acid for primary biliary cirrhosis. NIH National Library of Medicine National Centre for Biotechnology Information. Pubmed Central. December 2012. [Accessed on 10th July 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045744/
3. Keith D. Lindor, Kris V. Kowdley, Velimir A. C. Luketic, M. Edwyn Harrison, Timothy McCashland, Alex S. Befeler, Denise Harnois, Roberta Jorgensen, Jan Petz, Jill Keach, Jody Mooney, Carol Sargeant, Julie Braaten, Tamara Bernard, Debra King, Ellen Miceli, Jeff Schmoll, Tanya Hoskin, Prabin Thapa, Felicity Enders. High-dose ursodeoxycholic acid for the treatment of primary sclerosing cholangitis. NIH National Library of Medicine National Centre for Biotechnology Information. Pubmed Central. September 2009. [Accessed on 10th July 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758780/
4. Gustav Paumgartner, Ulrich Beuers. Mechanisms of action and therapeutic efficacy of ursodeoxycholic acid in cholestatic liver disease. NIH National Library of Medicine National Centre for Biotechnology Information. Pubmed.gov. February 2004. [Accessed on 10th July 2024] https://pubmed.ncbi.nlm.nih.gov/15062194/
5. Mitsubishi Tanabe Pharma Corporation. Efficacy and Safety Study of Ursodeoxycholic Acid to Treat Chronic Hepatitis C. NIH U.S. National Library of Medicine. ClinicalTrials.gov. March 2012. [Accessed on 10th July 2024] https://clinicaltrials.gov/ct2/show/NCT00200343
6. Glenmark Pharmaceuticals Europe Limited. Electronic Medicine Compendium (EMC). [Revised in March 2019] [Accessed on 10th July 2024] https://www.medicines.org.uk/emc/files/pil.10064.pdf
7. ABC Farmaceutici S.p.A. Health Products Regulatory Authority (HPRA). [Revised in July 2021] [Accessed 10th July 2024] http://www.hpra.ie/img/uploaded/swedocuments/b76d4c90-5f5f-4056-9635-5c78f70ab1dd.pdf
8. Dr. Falk Pharma GmbH. Electronic Medicine Compendium (EMC). [Revised in November 2014]. [Accessed on 10th July 2024] https://www.medicines.org.uk/emc/files/pil.2980.pdf
9. Glenmark Pharmaceuticals Europe Limited. Electronic Medicine Compendium (EMC). [Revised in March 2019]. [Accessed on 10th July 2024] https://www.medicines.org.uk/emc/files/pil.10064.pdf
10. DM Pharma. Ursodeoxycholic Acid. [Accessed on 10th July 2024] http://www.dmpharma.co.in/ursodeoxycholic.html
11. MIMS. Ursodeoxycholic Acid (Ursodiol). [Accessed on 10th July 2024] https://www.mims.com/india/drug/info/ursodeoxycholic%20acid?mtype=generic
12. Drug Bank. Ursodeoxycholic Acid (Ursodiol). [Accessed on 10th July 2024] https://go.drugbank.com/drugs/DB01586
USEFUL DIAGNOSTIC TESTS
• Complete Blood Count (CBC)/ Hemogram
• Liver Function Test (LFT)
• Bilirubin Profile
• Alkaline Phosphatase, Serum
• Bilirubin Direct, Serum
• Bilirubin Total, Serum
• Proteins, Serum
• Sgot/Ast
• Sgpt/Alt
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