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INTRODUCTION
TRIZACET COLD TABLET is a combination of Cetirizine, Paracetamol and Phenylephrine which belongs to the group of medicines called Antihistamines, Analgesic & Antipyretic, and Nasal Decongestant respectively. TRIZACET COLD TABLET is used to relieve symptoms of the common cold such as a blocked nose, runny nose, watery eyes, sneezing, congestion or stuffiness, fever, and headache. It reduces congestion and helps in easy breathing. Common cold is a viral infection that affects the nose and throat. Fever is generally increased body temperature in response to an infection.
Avoid alcohol consumption while taking TRIZACET COLD TABLET as it leads to excessive drowsiness. TRIZACET COLD TABLET is not recommended to use in patients with severe hypertension, coronary artery disease, or liver dysfunction. TRIZACET COLD TABLET should be used with caution in patients with occlusive vascular disease including Raynaud’s phenomenon, liver problems, and kidney problems.
TRIZACET COLD TABLET should be used with caution in pregnant women and it is not recommended to use in breastfeeding women. TRIZACET COLD TABLET is not recommended to use in children and adolescents below 12 years of age. Consult your doctor before taking it. The most common side effects of TRIZACET COLD TABLET are nausea, vomiting, fatigue, dry mouth, headache, abdominal pain, drowsiness, dizziness. Consult your doctor for advice if any of the above side effects worsen or persists for a longer duration.
USES OF TRIZACET COLD TABLET
It is used to relieve common cold symptoms such as:
- blocked, runny nose
- watery eyes
- sneezing
- congestion, stuffiness
- fever
- headache
HOW TRIZACET COLD TABLET WORKS
TRIZACET COLD TABLET is a combination of Cetirizine, Paracetamol and Phenylephrine where Cetirizine is an H1 receptor antagonist that works by blocking the action of a chemical messenger (histamine) responsible for runny nose, watery eyes, and sneezing. Paracetamol is an analgesic and antipyretic that acts by inhibiting the synthesis of prostaglandins (chemicals that cause inflammation, pain, and fever) which helps in reducing pain and fever. Phenylephrine is a nasal decongestant that acts by narrowing the small blood vessels providing temporary relief from congestion or stuffiness in the nose.
DIRECTIONS FOR USE
Take TRIZACET COLD TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew this medicine. The dose and duration for you will be decided by your physician depending on your age, body weight, and disease condition.
SIDE EFFECTS OF TRIZACET COLD TABLET
COMMON
- nausea
- vomiting
- fatigue
- dry mouth
- headache
- abdominal pain
- drowsiness
- dizziness
- diarrhoea
RARE
Stop taking TRIZACET COLD TABLET and contact your physician immediately if you experience the following side effects:
- allergic reactions (symptoms include erythema, rash, pruritus, urticaria, dyspnoea)
HOW TO MANAGE SIDE EFFECTS
Diarrhea
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling drowsy. Do not drink alcohol, as it can worsen your drowsiness. Consult your doctor if the symptom did not improve.
Nausea And Vomiting
Drink clear or ice-cold drinks. Eat light, bland foods. Avoid fried, greasy, or sweet foods. Eat slowly and smaller and more frequent meals, drink gradually larger amounts of clear liquids, avoid solid food until the vomiting episode has passed, and take rest. If the symptom does not improve, contact your doctor.
Stomach Pain
Try to rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your doctor.
WARNING & PRECAUTIONS
PREGNANCY
Monitoring requiredTRIZACET COLD TABLET should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor before taking it.
BREASTFEEDING
ContraindicatedTRIZACET COLD TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking it.
DRIVING AND USING MACHINES
Use with CautionDo not drive or operate any machines if you feel sleepy or drowsy after taking TRIZACET COLD TABLET.
ALCOHOL
Consult your doctorAvoid alcohol consumption while using TRIZACET COLD TABLET as it leads to excessive drowsiness.
KIDNEY
Use with CautionTRIZACET COLD TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking it.
LIVER
Consult your doctorTRIZACET COLD TABLET is not recommended in patients with severe hepatic dysfunction. It should be used with caution in patients with mild to moderate liver problems. Consult your doctor before taking it.
ALLERGY
ContraindicatedDo not take TRIZACET COLD TABLET if you are allergic to Cetirizine, Paracetamol, and Phenylephrine, or to any other ingredients of this medicine.
HEART DISEASE
ContraindicatedTRIZACET COLD TABLET is not recommended to use in patients with coronary artery disease and severe hypertension. Consult your doctor before taking it.
USE IN PEDIATRICS
ContraindicatedTRIZACET COLD TABLET is not recommended for use in children and adolescents below 12 years of age. Consult your healthcare professionals before giving it to your child.
USE IN GERIATRICS
Use with CautionTRIZACET COLD TABLET should be used with caution in elderly patients. Consult your doctor before taking.
OTHERS
Before taking TRIZACET COLD TABLET, inform your doctor if you have:
- occlusive vascular disease (Raynaud’s phenomenon)
INTERACTIONS
A. Drug-Drug interactions:
Before taking TRIZACET COLD TABLET, inform your doctor if you are taking any of the following medicine:
- medicines used to treat depression (Ex. isocarboxazid, phenelzine)
- medicines used for colds, cough, sleeping, or pain (Ex. chlorpheniramine, diazepam, opioids)
- medicines used to treat epilepsy (Ex. phenobarbital, phenytoin, sodium valproate, primidone, carbamazepine)
- medicines used to treat HIV infections (Ex. zidovudine)
- warfarin (medicine used to treat blood clotting)
- medicines used to treat nausea and vomiting (Ex. domperidone, metoclopramide)
Overdosage:
If you or anyone else accidentally takes too much of TRIZACET COLD TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are restlessness, irritability, palpitations, hypertension, difficulty in micturition, nausea, vomiting, thirst, convulsions, and liver damage.
SYNOPSIS
| Drug | : | Cetirizine, Paracetamol, Phenylephrine |
| Pharmacological Category | : | Anti-allergic, Analgesic, Antipyretic, Nasal Decongestants |
| Therapeutic Indication | : | Relieves common cold symptoms |
| Dosage Forms | : | Tablet, Syrup, Suspension, Drops |
MORE INFORMATION
- Keep TRIZACET COLD TABLET out of sight and reach of children
- Store TRIZACET COLD TABLET at room temperature
FAQs ABOUT TRIZACET COLD TABLET
Q: Is TRIZACET COLD TABLET cause drowsiness?
A: Yes, the most common side effect of TRIZACET COLD TABLET is drowsiness. Caution should be exercised while driving or operating heavy machines. Do not drive or handle heavy machines if you experience side effects like dizziness or drowsiness while taking TRIZACET COLD TABLET. Consult your healthcare professional if the symptom did not improve.
Q: Can I consume alcohol along with TRIZACET COLD TABLET?
A: No, it is not advisable to drink alcohol while taking TRIZACET COLD TABLET. Consuming alcohol along with TRIZACET COLD TABLET may aggravate the symptoms of TRIZACET COLD TABLET and cause severe liver damage, dizziness, and drowsiness. Consult your doctor before using it.
Q: Can I give TRIZACET COLD TABLET to my child?
A: TRIZACET COLD TABLET is not recommended for use in children and adolescents below 12 years of age. Consult your doctor before giving it to your child.
Q: Can we use TRIZACET COLD TABLET during pregnancy and breastfeeding?
A: TRIZACET COLD TABLET should be used with caution in pregnant women and it is not recommended for use in breastfeeding women. Consult your doctor before using it.
Q: Is TRIZACET COLD TABLET an antibiotic?
A: No, TRIZACET COLD TABLET is not an antibiotic. TRIZACET COLD TABLET is a combination of Cetirizine, Paracetamol and Phenylephrine which belong to the group of medicines called Anti-allergic, Analgesic, Antipyretic, and Decongestant respectively. It is used to relieve symptoms of the common cold such as a blocked nose, runny nose, fever, watery eyes and sneezing, allergic rhinitis, and nasal congestion. It does not treat bacterial infections.
Q: What precautions are to be taken if I forget to take TRIZACET COLD TABLET?
A: If you forget to take a dose of TRIZACET COLD TABLET, take it as soon as you remember. However, if it is time for the next scheduled dose skip the missed dose and take the usual prescribed dose. Do not take a double dose for the forgotten missed dose.
Q: Can I stop taking TRIZACET COLD TABLET if I feel better?
A: Do not stop taking TRIZACET COLD TABLET, even though you feel better. Your symptoms may reoccur if you stop taking TRIZACET COLD TABLET. Inform your doctor before stopping it.
REFERENCES
1. KD. Tripathi Autacoids and Related Drugs, Adrenergic System and Drugs, Nonsteroidal Anti-inflammatory Drugs and Antipyretic-Analgesics Essentials of medical pharmacology. Seventh edition. 2013. page no -166, 135, 192.
2. Aasim Naqvi; Valerie Gerriets. Cetirizine. NIH. National Library of Medicine. National Center for Biotechnology Information. StatPearls. November 2022. [Accessed on 3rd March 2023] https://www.ncbi.nlm.nih.gov/books/NBK549776/
3. Samir S Ayoub. Paracetamol (acetaminophen): A familiar drug with an unexplained mechanism of action. The Journal of Temperature. February 2021. [Accessed on 3rd March 2023] https://www.tandfonline.com/doi/full/10.1080/23328940.2021.1886392
4. Evan Richards; Michael J. Lopez; Christopher V. Maani. Phenylephrine. NIH. National Library of Medicine. National Center for Biotechnology Information. StatPearls. July 2022. [Accessed on 3rd March 2023] https://www.ncbi.nlm.nih.gov/books/NBK534801/
5. Phenylephrine. NIH. National Library of Medicine. [Accessed on 3rd March 2023] https://medlineplus.gov/druginfo/meds/a606008.html
6. Cetirizine, Paracetamol, and Phenylephrine. Tajlifeceiences. [Accessed on 3rd March 2023] https://tajlifesciences.com/
7. Cetirizine, Paracetamol, and Phenylephrine. Ikon remedies. [Accessed on 3rd March 2023] https://www.ikonremedies.com/product/rhinorest-cold-tablets/
8. Cetirizine, Paracetamol, and Phenylephrine. www.leeford.in. [Accessed on 3rd March 2023] https://www.leeford.in/product/617/coldfiz
AUTHOR DETAILS
Written By Dr. Janet.C, Pharm.D
Last updated on 07 Mar 2023 | 06:19 PM(IST)