TRITOFEN SYRUP 60ML

Introduction About TRITOFEN

TRITOFEN contains Ketotifen which belongs to the group of medicines called Antihistamines. It is used in prophylactic management of bronchial asthma and allergic conditions such as rhinitis (inflammation of the inside of the nose caused by an allergen like pollen, dust).

Bronchial asthma is a condition in which the airways narrow and swell, producing extra mucus. This can cause difficulty in breathing, trigger cough, wheezing and shortness of breath. Avoid consumption of alcohol during management with TRITOFEN. It is not recommended for use in patients having epilepsy.

Before taking TRITOFEN, inform your doctor if you are intolerant to certain sugars, have a history of epilepsy, diabetes. It is generally not recommended for use in pregnant and breastfeeding women. The most common side effects are agitation, irritability, inability to sleep and nervousness.

Uses Of TRITOFEN

To prevent:

• bronchial asthma
• rhinitis

How TRITOFEN Works

TRITOFEN works by blocking histamine (a substance in the body that causes allergic symptoms) and stops the release of mediators from cells involved in hypersensitivity reaction.

How to use TRITOFEN

Take TRITOFEN as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of TRITOFEN

Warning & Precautions

Pregnancy

TRITOFEN is not recommended for use in pregnant women or women planning to have a baby. Consult your doctor before taking it.

Breastfeeding

TRITOFEN is not recommended for use in breastfeeding women as it may pass in the breast milk. Consult your doctor before taking it.

Driving and Using Machines

Do not drive or use machines while taking TRITOFEN as you may feel drowsy and your reactions may be slower than usual.

Alcohol

Do not drink alcohol while taking TRITOFEN.

Allergy

Do not take TRITOFEN if you are allergic to Ketotifen or any other ingredients of this medicine

Interactions

A. Drug - Drug interactions:

Before taking TRITOFEN, inform your doctor if you are taking any of the following medicine:

• oral medicines for diabetes (Ex. biguanides, metformin)
• for asthma (Ex. budesonide, beclomethasone)
• to manage sleeplessness, anxiety, depression (Ex. diazepam, lorazepam)
• antihistamines to manage allergic reactions (Ex. brompheniramine, azelastine)
• anticoagulants (Ex. warfarin)

Overdosage:

If you or anyone else accidentally takes too much of TRITOFEN, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are blurred vision, confusion, convulsions, disorientation, dizziness, drowsiness (severe), faintness or lightheadedness when getting up from a lying or sitting position, fast, pounding, or irregular heartbeat or pulse, hyperexcitability, loss of consciousness, palpitations, sweating, unusual tiredness or weakness.

Synopsis

More Information

• Keep TRITOFEN out of reach of children
• Do not store above 25°C

FAQs About TRITOFEN

What is TRITOFEN used for?

TRITOFEN is used in the prophylactic management of bronchial asthma and allergic conditions such as rhinitis (inflammation of the inside of the nose caused by an allergen like pollen or dust).

How does TRITOFEN work?

TRITOFEN works by blocking histamine (a substance in the body that causes allergic symptoms) and stops the release of mediators from cells involved in hypersensitivity reaction.

Can I take medicine for diabetes while taking TRITOFEN?

Thrombocytopenia may occur in patients taking TRITOFEN at the same time as oral antidiabetic drugs (biguanides). Simultaneous administration of these drugs should therefore be avoided.

Can TRITOFEN cause weight gain in asthma patients?

Yes, TRITOFEN can cause an increase in appetite and hence weight gain. Consult your doctor before taking it for more information on this medicine.

Can TRITOFEN affect my sleep cycle?

Yes, it may cause some people to become excited, irritable, or nervous or to have trouble sleeping. These are symptoms of central nervous system stimulation and are especially likely to occur in children.

References

1. Goodman Gilmans. Ocular Pharmacology. The Pharmacological Basis of Therapeutics. Twelfth Edition. 2011. Page –1789.

2. Ketotifen. NIH. National Library of medicine. National center for biotechnology information. Pubchem. December 2022. [Accessed on 23rd May 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Ketotifen

3. S M Grant , K L Goa, A Fitton, E M Sorkin. Ketotifen. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in asthma and allergic disorders. NIH. National Library of medicine. National center for biotechnology information. Pubmed.gov. September 1990. [Accessed on 23rd May 2022] https://pubmed.ncbi.nlm.nih.gov/2226222/

4. Delpharm Orleans. Health Products Regulatory Authority (HPRA) [Accessed on 23rd May 2022] https://www.hpra.ie/img/uploaded/swedocuments/6fcc7356-bde1-496a-9ae0-070836b5e690.pdf

5. Ketotifen. Mayoclinic. [Revised in November 2022] [Accessed on 23rd May 2022] https://www.mayoclinic.org/drugs-supplements/ketotifen-oral-route/side-effects/drg-20064435

6. Ketotifen fumarate. CDSCO. [Accessed on 23rd May 2022] https://cdscoonline.gov.in/CDSCO/Drugs

Useful Diagnostic Tests

• Spirometry
• Allergy blood test

Author Details

Written By Dr. Shruthi M R - BDS

Reviewed For Accuracy By Dr. Rajnikant - MBBS, MD (Physiology)

Last updated on 16 Jan 2023 | 10:14 AM(IST)