Netmeds First Membership
Quick Links
Introduction About TRIOLMEZEST CH 40MG TABLET
TRIOLMEZEST CH 40MG TABLET is a combination of Amlodipine, Chlorthalidone and Olmesartan which belongs to the group of medicines called Antihypertensive agents. It is used to manage hypertension (high blood pressure). It can also be used to manage heart failure or stroke and can protect the function of kidneys particularly in patients who have both hypertension and type II diabetes mellitus.
It can also reduce the chances of fluid retention (edema) in the body that occurs due to some kidney or liver diseases. Take this medicine preferably in the mornings with food. While taking TRIOLMEZEST CH 40MG TABLET, do not drink alcohol/grapefruit juice or go for a low-salt diet, as they may make further reduce your blood pressure. Consult your doctor for the best diet that can suit your health condition.
Before taking TRIOLMEZEST CH 40MG TABLET inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have diabetes, high blood cholesterol levels, dehydration, or very low blood sodium, potassium or magnesium levels as a precaution.
TRIOLMEZEST CH 40MG TABLET is not recommended for use in patients with other severe heart problems such as narrowing of heart valves or cardiogenic shock. It is also not suitable for use in patients with severe hypotension (low blood pressure).
Do not take TRIOLMEZEST CH 40MG TABLET if you are pregnant, think you may be pregnant or planning to have a baby or breastfeeding without consulting your doctor.
The most common side effects of taking TRIOLMEZEST CH 40MG TABLET are headache, dizziness, tiredness, weakness, high blood uric acid levels, low blood sodium or magnesium levels, diabetes, high blood potassium levels, low blood pressure, impotence in men, sore throat, runny nose, cough, flu-like symptoms, urinary tract infections and increased blood cholesterol levels. Contact your doctor if any of these side effects trouble you.
Uses Of TRIOLMEZEST CH 40MG TABLET
It is used to manage and prevent:
- Hypertension (high blood pressure)
- Heart failure, Stroke
- Edema (fluid retention)
- Kidney damage among diabetic patients
How TRIOLMEZEST CH 40MG TABLET Works
TRIOLMEZEST CH 40MG TABLET relaxes the blood vessels supplying various organs (such as heart, kidney, brain or others) which allows the blood to flow more smoothly across the blood vessels. It also removes the excess fluids and electrolytes (sodium and water) from the body in the form of urine which helps in reducing edema and blood thickness. Collectively, these actions improve blood flow, reduces the strain on the heart and helps the heart to pump more blood with less pressure.
How to use TRIOLMEZEST CH 40MG TABLET
Always take TRIOLMEZEST CH 40MG TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. TRIOLMEZEST CH 40MG TABLET is preferably taken during the mornings with food.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Do not stop taking TRIOLMEZEST CH 40MG TABLET without consulting your doctor.
Overdose
If you or anyone else accidentally took more TRIOLMEZEST CH 40MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage might include dizziness, fainting, light-headedness, weakness, shock, cool or clampy skin, and shortness of breath.
Side Effects Of TRIOLMEZEST CH 40MG TABLET
Common side effects of TRIOLMEZEST CH 40MG TABLET:
- headache, dizziness
- tiredness, weakness
- high blood uric acid levels
- low blood sodium levels (causing tiredness, confusion, muscle twitching, fits or fainting)
- low blood magnesium levels
- high or low blood sugar levels
- high blood potassium levels
- skin rash
- low blood pressure which may make you feel dizzy while standing up
- impotence in men
- nausea, vomiting, stomach pain, constipation, diarrhea, indigestion
- sore throat, runny nose, cough, flu-like symptoms
- back pain, joint pain
- urinary tract infections
- increased blood cholesterol levels
- increased liver enzymes levels
Stop taking TRIOLMEZEST CH 40MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth or throat which can lead to difficulty in breathing or swallowing)
- severe skin reactions (such as skin rash with itching and redness, blistering and peeling of skin, skin swelling and inflammation of mucous membrane)
- chest pain, shortness of breath (signs of heart attack)
- inflammation of pancreas (causing severe stomach pain that radiates to the back side of the body)
How To Manage Side Effects
Constipation
Eat plenty of fibre rich foods such as fresh fruits, vegetables, and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Nausea And Vomiting
Take TRIOLMEZEST CH 40MG TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.
Warning & Precautions
Pregnancy
ContraindicatedTRIOLMEZEST CH 40MG TABLET is not recommended for use in pregnant women as it may cause serious harm to the growing foetus. Therefore, consult your doctor before taking it.
Breastfeeding
ContraindicatedTRIOLMEZEST CH 40MG TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk and harm the nursing infant. Therefore, consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or handle any heavy tools or machines if you experience dizziness or drowsiness after taking TRIOLMEZEST CH 40MG TABLET.
Alcohol
ContraindicatedAvoid consumption of alcohol while taking TRIOLMEZEST CH 40MG TABLET as it might make you feel dizzier and drowsier.
Kidney
Consult your doctorTRIOLMEZEST CH 40MG TABLET is not recommended for use in patients with severe kidney problems (such as kidney stones, renal artery stenosis, dialysis). It should be used with caution in patients with other kidney problems. Therefore, consult your doctor before taking it.
Liver
Consult your doctorTRIOLMEZEST CH 40MG TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with mild to moderate liver diseases. Therefore, consult your doctor before taking it.
Allergy
ContraindicatedDo not take TRIOLMEZEST CH 40MG TABLET if you are allergic to Amlodipine, Chlorthalidone or Olmesartan.
Heart Disease
Consult your doctorTRIOLMEZEST CH 40MG TABLET is not recommended for use in patients with severe heart problems such as heart failure, aortic stenosis (narrowing of arteries) or cardiogenic shock (inability of heart to pump blood). It should be used with caution in patients having a history of recent heart, heart failure, irregular heartbeat, coronary heart disease or problems related with heart muscle or valves). Therefore, consult your doctor before taking it.
Use In Pediatrics
Consult your doctorTRIOLMEZEST CH 40MG TABLET is not recommended for use in children aged below 6 years. It should be used in children and adolescents (aged between 6-17 years) only if prescribed by the physician. Therefore, consult your doctor for advice before administration.
Use In Geriatrics
Use with CautionTRIOLMEZEST CH 40MG TABLET should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor for advice before taking it.
Other Warnings for TRIOLMEZEST CH 40MG TABLET
Before taking TRIOLMEZEST CH 40MG TABLET, inform your doctor if you have:
- severe uncontrollable increase in blood pressure (hypertensive crisis)
- have diabetes
- have high blood cholesterol levels
- have high blood potassium levels
- are undergoing any surgery (including dental surgery)
- are severely dehydrated (due to diarrhea, vomiting or excess sweating)
- are on a low-salt diet
- have primary hyperaldosteronism (problems in adrenal gland)
- are undergoing any major surgery
Who should not take TRIOLMEZEST CH 40MG TABLET
TRIOLMEZEST CH 40MG TABLET is not recommended for use if you:
- have diabetes related kidney problems
- have abnormally very low blood pressure
- are not passing urine at all
- have low blood potassium levels (hypokalemia)
- have low blood sodium levels (signs include tiredness, confusion, muscle twitching, fits or lack of consciousness)
- high blood calcium levels
- have gout
- have Addison’s disease (a problem in adrenal gland)
Drug - Drug interaction
Before taking TRIOLMEZEST CH 40MG TABLET, inform your doctor if you are taking any of the following medicines such as:
- other medicines used to reduce elevated blood pressure and other heart problems (Ex. atenolol, propranolol, enalapril, lisinopril, amlodipine, nifedipine, diltiazem, verapamil, methyldopa, guanethidine)
- ketoconazole, itraconazole (used to manage fungal infections)
- ritonavir, indinavir, nelfinavir (used in management of HIV infections)
- rifampicin, erythromycin, clarithromycin (used to manage bacterial infections)
- dantrolene (a medicine used to manage muscle spasms)
- medicines used to control elevated cholesterol levels (Ex. simvastatin, cholestyramine, colesevelam)
- potassium supplements or potassium-sparing diuretics such as spironolactone, triamterene or amiloride (used to retain or increase potassium levels in the body)
- antacids (medicines used to neutralize stomach acid) Ex. aluminium hydroxide, magaldrate
- medicines used to manage graft rejection and to suppress immune functions (such as tacrolimus, sirolimus, temsirolimus, everlimus, cyclosporine)
- St. John’s wort (an herbal medicine used to manage depression)
- corticosteroids (used to manage pain and inflammation) Ex. prednisolone, betamethasone
- corticotropin (a medicine used to correct hormone problems)
- medicines used for cancer (Ex. cyclophosphamide, methotrexate)
- medicines used to manage asthma (such as salbutamol, formoterol)
- amphotericin B (a medicine used to manage fungal infections)
- carbenoxolone (a medicine used to manage mouth ulcers)
- anticholinergics (used to manage stomach muscle spasms) such as atropine, hyoscine
- lithium (a medicine used to manage various mental health problems)
- digoxin (a medicine used to manage irregular heartbeat)
- allopurinol (a medicine used to manage gout)
- amantadine (a medicine used for parkinsonism or viral infections)
- non-steroidal anti-inflammatory drugs (used for pain relief) such as indomethacin, celecoxib, ibuprofen, aspirin
- calcium and vitamin D supplements
- tricyclic antidepressants (used to manage depression) Ex. amitriptyline, nortriptyline, imipramine
- antipsychotics (used to manage mental illness) Ex. chlorpromazine
- baclofen (a medicine used for relaxing muscles)
- amifostine (a kidney protectant used along with chemotherapeutic agents)
Drug - Food interaction
Avoid drinking grapefruit juice while taking TRIOLMEZEST CH 40MG TABLET, as it could further decrease your blood pressure.
Synopsis
|
Drug |
: |
Amlodipine, Chlorthalidone, Olmesartan |
|
Pharmacological Category |
: |
Calcium Channel Blockers, Thiazide Diuretics, Angiotensin-II Receptor Blockers |
|
Therapeutic Indication |
: |
Hypertension, Angina, Heart failure, Edema |
|
Dosage Forms |
: |
Tablet |
More Information
- Keep TRIOLMEZEST CH 40MG TABLET out of the sight and reach of children
- Store TRIOLMEZEST CH 40MG TABLET at room temperature
FAQs About TRIOLMEZEST CH 40MG TABLET
Q: What are the uses of Triolmezest CH 40mg Tablet?
A: Triolmezest CH 40mg Tablet is used to manage hypertension (high blood pressure). It can also be used to manage heart failure or stroke and can protect kidney function, particularly in patients with both hypertension and type II diabetes mellitus. It may also reduce fluid retention (edema) associated with certain kidney or liver diseases.
Q: What type of a medicine is Triolmezest CH 40mg Tablet?
A: It relaxes blood vessels and helps remove excess fluids and electrolytes through urine. These actions improve blood flow, reduce fluid retention, decrease strain on the heart, and help lower blood pressure.
Q: What happens when I stop taking Triolmezest CH 40mg Tablet?
A: Do not stop taking it without consulting your doctor, as your blood pressure may rise again. Continue treatment for the duration prescribed by your doctor.
Q: What is the best time to take Triolmezest CH 40mg Tablet?
A: It is generally recommended to take this medicine in the morning with food. Follow your doctor's advice.
Q: What to do if I forgot to take a dose of Triolmezest CH 40mg Tablet?
A: Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not take a double dose.
Q: What precautions should be followed while taking Triolmezest CH 40mg Tablet?
A: Inform your doctor about any liver, kidney, blood pressure, or heart problems. Avoid use during pregnancy and breastfeeding. Attend regular check-ups and blood tests as advised.
Q: Can I consume alcohol while taking Triolmezest CH 40mg Tablet?
A: Avoid alcohol, as it may increase dizziness and drowsiness.
Q: What happens if I accidentally take more Triolmezest CH 40mg Tablet?
A: Seek immediate medical attention. Symptoms may include dizziness, fainting, weakness, shock, cool or clammy skin, and shortness of breath.
Q: Can I take Triolmezest CH 40mg Tablet daily?
A: Take it exactly as prescribed by your doctor. Your doctor will determine whether daily use is appropriate for you.
Q: What are the side effects of Triolmezest CH 40mg Tablet?
A: Common side effects include headache, dizziness, tiredness, weakness, electrolyte changes, low blood pressure, cough, sore throat, urinary tract infections, and increased cholesterol levels. Contact your doctor if these persist or worsen.
Q: Can I stop taking Triolmezest CH 40mg Tablet once my symptoms subside?
A: No. Hypertension often requires long-term treatment. Stopping the medicine without medical advice may cause your blood pressure to increase again.
Q: Can Triolmezest CH 40mg Tablet causes electrolyte imbalance?
A: Yes. It may alter sodium and potassium levels. Your doctor may monitor these levels through blood tests. Seek medical advice if you experience symptoms such as muscle weakness, irregular heartbeat, confusion, nausea, or vomiting.
Q: Can the use of Triolmezest CH 40mg Tablet affect my sexual life?
A: Yes. It may cause impotence in men and reduced sex drive in both men and women. Consult your doctor if this becomes troublesome.
Q: Can Triolmezest CH 40mg Tablet be taken during pregnancy?
A: No. It is not recommended during pregnancy because it may harm the developing baby. Consult your doctor.
Q: Is Triolmezest CH 40mg Tablet safe to use in kidney disease?
A: It is not recommended in severe kidney conditions and should be used cautiously in other kidney disorders. Consult your doctor before use.
Q: Can the use of Triolmezest CH 40mg Tablet affect the liver?
A: Yes. It may affect liver function and increase liver enzyme levels. Use with caution in patients with liver problems.
Q: Does Triolmezest CH 40mg Tablet cause frequent urination?
A: Yes. Because it contains chlorthalidone, a diuretic, it may increase urination. Taking it at least 5 hours before bedtime may help reduce nighttime urination.
References
1. KD Tripathi. Antianginal and Other Anti-ischaemic Drugs. Antihypertensive Drugs. Diuretics. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 549, 562, 559 & 583. 561 & 562.
2. Connor C. Kerndt; Jayesh B. Patel. Chlorthalidone. StatPearls [Internet]. NIH. National Library of Medicine, National Center for biotechnology information. PMC. PubMed Central. November 2022. [Accessed on 30th May 2026] 
3. Xiaoshen Zhang, Han Zhang, Yuxia Ma, Wenliang Che, and Michael R. Hamblin. Management of Hypertension Using Olmesartan Alone or in Combination. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. March 2017. [Accessed on 30th May 2026] 
4. Dr. Reddy’s Laboratories (UK) Ltd. Electronic Medicines Compendium (EMC). [Revised in August 2018] [Accessed on 30th May 2026]
5. Glenmark Pharmaceuticals Europe Limited. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 30th May 2026]
6. Atlantic Pharma. Electronic Medicines Compendium (EMC). [Revised in September 2020] [Accessed on 30th May 2026]