Trigan MF Tablet 10'S

Introduction About TRIGAN MF TABLET

TRIGAN MF TABLET is a combination of Dicyclomine, Mefenamic Acid, and Paracetamol which belong to the groups of medicines called Anticholinergic, Non-Steroidal Anti-Inflammatory Drug (NSAID), and Antipyretic respectively. It is used to manage abdominal cramps, stomach pain and discomfort in the space between the chest and pelvis.

Avoid consuming alcohol while taking TRIGAN MF TABLET, as this may lead to unwanted effects. Avoid overheating by avoiding strenuous work or exercise in hot weather and using hot baths as they cause heatstroke due to less sweat. Before taking TRIGAN MF TABLET, inform your doctor if you have diarrhoea, ulcerative colitis, hyperthyroidism, hypertension, liver problems, known or suspected prostatic hypertrophy, or heart problems.

TRIGAN MF TABLET is not recommended for use by pregnant or breastfeeding women. TRIGAN MF TABLET is not recommended for use in infants younger than 6 months of age. The most common side effects of this medicine are nausea, vomiting, indigestion, diarrhoea, loss of appetite, sleepiness, weakness, nervousness, dry mouth, blurred vision, and heartburn. Contact your physician if any of your symptoms get worse or persist.

Uses Of TRIGAN MF TABLET

• Manage abdominal cramps and stomach pain

How TRIGAN MF TABLET Works

TRIGAN MF TABLET is a combination of Dicyclomine, Mefenamic Acid, and Paracetamol. Dicyclomine is an anticholinergic drug that works by relaxing the muscles in the stomach and gut (intestine). It stops sudden muscle contractions (spasms) and relieves pain, cramps, bloating, and discomfort. Paracetamol is an antipyretic (fever reducer), and mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID). They block the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Together, the combination of these three medicines—Dicyclomine, Mefenamic Acid, and Paracetamol-relieves abdominal pain.

How to use TRIGAN MF TABLET

Take TRIGAN MF TABLET as advised by your physician. Swallow the medicine with enough water. Do not crush or chew the medicine. The correct dose and duration will be decided by your physician for you depending on your age, body weight, and disease condition.

Side Effects Of TRIGAN MF TABLET

How To Manage Side Effects

Nausea or vomiting:

Take this medicine with meals or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. Consult your physician if your symptoms get worse.

Dizziness:

Lie down until the dizziness goes away, and then move slowly and carefully. Rest more and drink more fluids. Consult your physician if your symptoms get worse.

Dry Mouth:

Drink water more frequently, do regular mouth rinses, and use sugarless candy. Consult your physician if your symptoms get worse.

Diarrhoea:

Drink lots of fluids, like water or fruit juice, to keep yourself hydrated. Do not consume any medicine on your own without consulting your physician. Consult your physician if your symptoms get worse.

Warning & Precautions

Pregnancy

TRIGAN MF TABLET is generally not recommended for use in pregnant women. Contact your doctor before taking TRIGAN MF TABLET.

Breastfeeding

TRIGAN MF TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking TRIGAN MF TABLET.

Driving and Using Machines

Do not drive or operate any machines if you feel sleepiness, dizziness, or blurred vision after taking TRIGAN MF TABLET.

Alcohol

Avoid consumption of alcohol while taking TRIGAN MF TABLET as it may lead to unwanted effects.

Kidney

TRIGAN MF TABLET is not recommended to use in patients with known kidney disease. Contact your doctor before taking TRIGAN MF TABLET.

Liver

TRIGAN MF TABLET should be used with caution in patients with known liver disease. Contact your doctor before taking TRIGAN MF TABLET.

Allergy

Do not take TRIGAN MF TABLET if you are allergic to Dicyclomine, Mefenamic acid, Paracetamol, other NSAIDs, or other ingredients of this medicine.

Heart Disease

TRIGAN MF TABLET should be used with caution in patients with heart diseases like coronary heart disease, congestive heart failure, and cardiac tachyarrhythmia. Contact your doctor before taking TRIGAN MF TABLET.

Interactions

A. Drug-Drug interactions:

Before taking TRIGAN MF TABLET, inform your physician, if you are using:

• medicine used to manage Parkinson's disease (Ex. amantadine)
• medicines used as antiarrhythmics (prevent and manage a heart rhythm that's too fast or irregular) (Ex. quinidine)
• medicine used to manage allergies (Ex. chlorpheniramine)
• medicines used as antipsychotics (Ex. phenothiazines)
• medicines used to manage anxiety, seizures, and insomnia (Ex. alprazolam, diazepam)
• medicines used to manage depression (monoamine oxidases (MAO) inhibitors like isocarboxazid and tricyclic antidepressants (Ex. amitriptyline)
• medicines used as narcotic analgesics (Ex. meperidine)
• using of nitrates and nitrites
• medicines used as a sympathomimetic (Ex. amphetamine)
• other medicines having an anticholinergic activity (Ex. amantadine)
• medicines used to manage nausea and vomiting (Ex. metoclopramide)

Overdosage:

If you or anyone else accidentally took too much of TRIGAN MF TABLET, consult your doctor immediately. The symptoms of overdosage may include headache, nausea, vomiting, blurred vision, dilated pupils, hot dry skin, dizziness, dryness of the mouth, difficulty in swallowing, and CNS stimulation including convulsion.

Synopsis

More Information

• Keep out of reach from children
• Store TRIGAN MF TABLET at a room temperature

FAQs About TRIGAN MF TABLET

Q: What is TRIGAN MF TABLET?

A: TRIGAN MF TABLET is a combination of Dicyclomine, Mefenamic Acid, and Paracetamol which belong to the groups of medicines called Anticholinergic, Non-Steroidal Anti-Inflammatory Drug (NSAID), and Antipyretic respectively. It is used to manage abdominal cramps.

Q: What are the common side effects of TRIGAN MF TABLET?

A: The most common side effects of TRIGAN MF TABLET are nausea, vomiting, indigestion, diarrhoea, loss of appetite, sleepiness, weakness, nervousness, dry mouth, blurred vision, and heartburn. Contact your physician if any of the above symptoms worsen.

Q: What precaution is to be taken before taking TRIGAN MF TABLET?

A: Before taking TRIGAN MF TABLET inform your doctor if you have diarrhea, ulcerative colitis, hyperthyroidism, hypertension, liver problems, known or suspected prostatic hypertrophy, or heart problems.

Q: Is it safe to use TRIGAN MF TABLET during pregnancy and breastfeeding?

A: TRIGAN MF TABLET is not recommended for use by pregnant or breastfeeding women. Please contact your doctor before taking TRIGAN MF TABLET.

Q: Is it safe to use TRIGAN MF TABLET in patients with heart problems?

A: TRIGAN MF TABLET should be used with caution in patients with heart diseases like coronary heart disease, congestive heart failure, and cardiac tachyarrhythmia. Contact your doctor before taking TRIGAN MF TABLET.

References

1. KD Tripathi. Antiemetic, Prokinetic, and Digestant Drugs and Nonsteroidal Anti-inflammatory Drugs and Antipyretic-Analgesics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 663, 192-209.

2. SR Lokhande, S.M. Mhetre, S.S. Pekamwar, T.M. Kalyankar. Development and validation of reverse phase HPLC method for simultaneous estimation of Dicyclomine hydrochloride, Mefenamic acid and paracetamol in the tablet dosage form. World Journal of Pharmacy and Pharmaceutical Sciences.  July 2022. [Accessed on 16th July 2022] https://www.wjpps.com/Wjpps_controller/abstract_id/83

3. Srivastava Rajat, Mishra Manoj Kumar, Patel Amit Kumar, Singh Abhishek and Kushwaha Krishna. An insight of non-steroidal anti-inflammatory drug mefenamic acid: A review. GSC Biological and Pharmaceutical Sciences. April 2019. [Accessed on 16th July 2022] https://gsconlinepress.com/journals/gscbps/content/insight-non-steroidal-anti-inflammatory-drug-mefenamic-acid-review

4. Sarah Jefferies, Manoj Saxena and Paul Young. Paracetamol in critical illness: A review. The Australasian Academy of Critical Care Medicine. March 2012. [Accessed on 16th July 2022] https://www.researchgate.net/publication/221690139_Paracetamol_in_critical_illness_A_review

5. Medzeel Life Science. Dicyclomine HCL, Paracetamol & Mefenamic Acid Tablets. [Accessed on 16th July 2022] https://www.medzeellifescience.com/dicyclomine-hcl-paracetamol-mefenamic-acid-tablets-6569782.html

6. BSA Pharma Inc. Meclospas. [Accessed on 16th July 2022] https://www.bsapharmainc.in/dicyclomine-mefenamic-acid-paracetamol-tablets-meclospas/

7. Invision Medi Sciences Pvt. Ltd. Biospas Tablet. [Accessed on 16th July 2022] http://www.invisionmedi.com/category/biospas-tablets.htm

8. Axcan Scandipharm Inc. US Food and Drug Administration. [Revised on July 2006] [Accessed on 16th July 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/007409s040,007961s026,008370s031lbl.pdf

9. PONSTEL. US Food and Drug Administration. [Revised on February 2008] [Accessed on 16th July 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/015034s040lbl.pdf

10. Accord Limited. Electronic Medicines Compendium (EMC). [Revised in November 2021] [Accessed on 16th July 2022] https://www.medicines.org.uk/emc/files/pil.5916.pdf

11. Reliable 1 Laboratories. Electronic Medicines Compendium (EMC). [Revised in December 2021] [Accessed on 16th July 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=25626b46-78f8-7226-e054-00144ff8d46c

Author Details

Written By Dr. Dhivakaran R - BDS

Reviewed For Accuracy By Dr. Vrushabhakumar Jitendra Shah. - MBBS

Last updated on 26 Dec 2022 | 04:23 PM(IST)