Sun Pharmaceutical Industries Ltd

Trapic 500mg Tablet 10'S

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Introduction About TRAPIC 500MG TABLET

Trapic 500mg Tablet contains Tranexamic Acid which belongs to the group of medicines called Antifibrinolytics. It is used in the management of bleeding in conditions such as heavy menstrual bleeding in women, bleeding inside the digestive system (Ex. inflammatory bowel disease), bleeding from the nose, blood in urine (not caused by the kidney (renal parenchyma)), control bleeding after dental extraction in patients with coagulopathies and after cervix surgery.

Trapic 500mg Tablet is not recommended for use in patients with blood clotting disorder or consumption coagulopathy, kidney disease, fits or seizure disorder, irregular menstrual cycle, acquired disturbances of color vision, venous or arterial thrombosis, active thromboembolic diseases such as deep vein thrombosis, pulmonary embolism and cerebral thrombosis, subarachnoid hemorrhage and blood in urine during periods.

Before taking Trapic 500mg Tablet, inform your doctor if you had or have changes in normal bleeding pattern, family history of endometrial cancer, abnormal bleeding between periods, bleeding during or after sexual intercourse, premenstrual pain, lower abdominal pain, bleeding after menopause, are at risk of having a blood clot, diabetic, overweight, polycystic ovary syndrome (PCOS).

Trapic 500mg Tablet should be used with caution in pregnant and breast-feeding women only if clearly advised by the doctor. Your doctor may recommend you to take relevant tests to understand your existing condition.

Safety and effectiveness of Trapic 500mg Tablet in children and adolescents below 18 years of age has not been established yet and it is not recommended for use in elderly women after menopause (stoppage of periods).  

The most common side effects of taking Trapic 500mg Tablet are nausea, vomiting, diarrhea, headache, tiredness and stomach pain. Consult your doctor immediately if any of the side effect worsens.     

Uses Of TRAPIC 500MG TABLET

It is used to manage bleeding in conditions such as,  

  • heavy menstrual bleeding in women
  • bleeding from the nose
  • bleeding inside the digestive system (gastrointestinal system, Ex. inflammatory bowel disease))  
  • blood in urine (not caused by the kidney (renal parenchyma))
  • bleeding after undergoing surgery (such as dental extraction in patients with coagulopathies, cervix surgery)  

Benefits of TRAPIC 500MG TABLET

  • Helps reduce excessive bleeding by preventing the premature breakdown of blood clots.
  • Supports the body's natural clot stabilization process.
  • Commonly prescribed for conditions associated with abnormal bleeding.  
  • Helps reduce menstrual blood loss during heavy periods.
  • May improve day-to-day comfort during menstruation when used as prescribed.
  • Helps reduce the need for frequent sanitary product changes in women with heavy menstrual bleeding.
  • Commonly used to minimize bleeding following dental extractions and certain surgical procedures.
  • Supports clot stability during the recovery period.  
  • Begins supporting clot stability soon after absorption.
  • Helps maintain existing blood clots until normal healing occurs.
  • Available as an oral tablet for easy administration.
  • Can be incorporated into the prescribed treatment plan without injections in many situations.

How TRAPIC 500MG TABLET Works

Trapic 500 mg Tablet contains Tranexamic Acid, which belongs to the class of antifibrinolytic medicines.

Step 1: Formation of a Blood Clot

  • When a blood vessel is injured, the body naturally forms a fibrin clot to stop bleeding.
  • Fibrin acts like a mesh that holds blood cells together and seals the injured blood vessel.

Step 2: Prevention of Premature Clot Breakdown

  • Normally, an enzyme called plasmin breaks down fibrin clots after healing begins.
  • In some conditions, plasmin becomes overactive and dissolves clots too early, leading to continued bleeding.

Step 3: Blocks Plasmin Formation and Activity

  • Tranexamic Acid binds to plasminogen and prevents its conversion to plasmin.
  • It also reduces the ability of plasmin to bind to fibrin.
  • As a result, fibrin clots remain intact for longer.

Step 4: Stabilizes the Clot

  • By protecting fibrin from breakdown, the medicine helps stabilize existing blood clots.
  • This supports normal clot persistence at the site of bleeding.

Step 5: Helps Reduce Blood Loss

  • Stabilized clots reduce ongoing bleeding until the damaged blood vessel heals naturally.
  • The medicine does not create new clots; instead, it helps preserve clots that the body has already formed.

How to use TRAPIC 500MG TABLET

Before Taking the Medicine

  • Take Trapic 500 mg Tablet only on the advice of a healthcare professional.
  • Follow the prescribed dose and duration carefully.
  • Inform your healthcare professional about all medicines, supplements, and any history of kidney disease or blood clotting disorders before starting therapy.

How to Take the Tablet

  • Swallow the tablet whole with a glass of water.
  • Do not crush, chew, or break the tablet.
  • It may be taken with or without food; taking it after food may help reduce stomach discomfort.
  • Take the medicine at the same time each day if multiple doses are prescribed.

During Treatment

  • Continue taking the medicine for the full duration recommended by your healthcare professional.
  • Do not stop the medicine early unless advised.
  • Maintain adequate hydration unless instructed otherwise.
  • Attend follow-up appointments if recommended.

What if I forgot to take TRAPIC 500MG TABLET

  • Take the missed dose as soon as you remember.
  • If it is nearly time for the next scheduled dose, skip the missed dose.
  • Do not take two doses together to make up for a missed dose.

Overdose

  • Seek immediate medical attention if an overdose is suspected.
  • Symptoms may include nausea, vomiting, dizziness, or low blood pressure. headache, diarrhea, impaired vision, abnormal mental status, skin rashes, and fits or seizures.

Side Effects Of TRAPIC 500MG TABLET

Common

  • nausea, vomiting
  • diarrhea, stomach pain
  • headache
  • sinus and nasal symptoms
  • back, muscle or joint pain
  • muscle cramps
  • migraine
  • anemia
  • tiredness

When to consult aa doctor?

  • impaired vision (especially color), blood clot in the eye
  • itchy, red or swollen skin
  • serious blood clots
  • pain or feelings of heaviness in the chest
  • pain or swelling in the arms or legs
  • sudden shortness of breath, fainting
  • coughing up blood

Warning & Precautions

Pregnancy

Use with Caution

Trapic 500mg Tablet should be used with caution in pregnant women only if considered clearly necessary. Inform your doctor immediately if you become pregnant or think you may be pregnant before using it.

Breastfeeding

Use with Caution

Trapic 500mg Tablet should be used with caution in breastfeeding women only if advised by the doctor as it may pass through the breast milk. Consult your doctor before taking.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you experience dizziness after taking Trapic 500mg Tablet

Kidney

Consult your doctor

Trapic 500mg Tablet is not recommended for use in patients with severe kidney impairment.  Trapic 500mg Tablet should be used with caution in patients with mild to moderate kidney impairment and your doctor may adjust the dose depending upon kidney function. Consult your doctor for advice before taking.

Liver

Consult your doctor

No dose adjustment is required in patients with hepatic impairment. Consult your doctor for advice.  

Allergy

Contraindicated

Do not take Trapic 500mg Tablet if you are allergic to Tranexamic Acid or any other ingredients of this medicine.

Lungs

Contraindicated

Trapic 500mg Tablet is not recommended for use in patients with pulmonary embolism (arteries of the lungs are blocked by clot). Consult your doctor before taking Trapic 500mg Tablet.  

Use In Pediatrics

Consult your doctor

Safety and effectiveness of Trapic 500mg Tablet in children and adolescents below 18 years of age has not been established yet. Consult your child’s doctor for advice.  

Use In Geriatrics

Contraindicated

Trapic 500mg Tablet is not recommended for use in elderly women after menopause (stoppage of periods). Consult your doctor before taking Trapic 500mg Tablet.

Other Warnings for TRAPIC 500MG TABLET

Before taking Trapic 500mg Tablet, inform your physician if you:

  • have changes in normal bleeding pattern
  • have family history of endometrial cancer
  • have abnormal bleeding between the periods
  • have bleeding during or after sexual intercourse
  • have premenstrual pain or lower abdominal pain
  • have bleeding after menopause
  • have obstruction of the urinary tract
  • are at a risk for the formation of a blood clot
  • are diabetic
  • are overweight
  • have polycystic ovary syndrome (PCOS)

Who should not take TRAPIC 500MG TABLET

Trapic 500mg Tablet is not recommended for use if you:

  • have a blood clotting disorder (consumption coagulopathy)
  • have history of fits or seizure disorder
  • have an irregular menstrual cycle
  • have acquired disturbances of color vision
  • have history of venous or arterial thrombosis (blood clot in artery/veins)
  • have deep vein thrombosis, cerebral thrombosis (blood clot of cerebral vein in brain)
  • have subarachnoid hemorrhage (bleeding in space between brain and tissue covering the brain)
  • have blood in urine between periods

Drug - Drug interaction

1. Hormonal Contraceptives (Estrogen-Containing Medicines)

Using tranexamic acid with estrogen-containing hormonal contraceptives may increase the risk of blood clot-related complications.

Examples:

  • Ethinyl estradiol + levonorgestrel
  • Ethinyl estradiol + drospirenone
  • Ethinyl estradiol + desogestrel
  • Contraceptive patches
  • Vaginal contraceptive rings

2. Anticoagulants (Blood Thinners)

Tranexamic acid may oppose the effects of medicines that reduce blood clotting.

Examples:

  • Warfarin
  • Heparin
  • Enoxaparin
  • Dabigatran
  • Rivaroxaban
  • Apixaban
  • Edoxaban

3. Antiplatelet Medicines

Medicines that reduce platelet function may alter the overall balance of blood clotting when used with tranexamic acid.

Examples:

  • Aspirin
  • Clopidogrel
  • Prasugrel
  • Ticagrelor
  • Dipyridamole

4. Thrombolytic (Clot-Dissolving) Medicines

These medicines dissolve blood clots and may reduce the effectiveness of tranexamic acid.

Examples:

  • Alteplase
  • Streptokinase
  • Urokinase
  • Tenecteplase
  • Reteplase

5. Coagulation Factor Concentrates

Using tranexamic acid with clotting factor preparations may increase the possibility of excessive clot formation in susceptible individuals.

Examples:

  • Factor IX concentrate
  • Prothrombin complex concentrate (PCC)
  • Activated prothrombin complex concentrate (aPCC)
  • Anti-inhibitor coagulant complex

6. Hemostatic Medicines

Using multiple medicines that promote clot stability may require additional medical supervision.

Examples:

  • Etamsylate
  • Fibrin sealants
  • Topical thrombin preparations

7. Retinoids

Certain retinoids used in cancer therapy may increase the risk of clotting complications when combined with tranexamic acid.

Examples:

  • Tretinoin (All-trans retinoic acid)

8. Medicines That Increase the Risk of Thrombosis

Some medicines may independently increase the likelihood of blood clot formation.

Examples:

  • Tamoxifen
  • Raloxifene
  • Estrogen replacement therapy

Synopsis

Drug

:  

Tranexamic Acid

Pharmacological Category

:  

Antifibrinolytics

Therapeutic Indication

:  

Prevent and manages bleeding in various conditions

Dosage Forms

:  

Tablet, Gel, Injection

More Information

1. How Tranexamic Acid Supports the Body's Natural Clotting Process

Trapic 500 mg Tablet contains Tranexamic Acid, which belongs to the antifibrinolytic class of medicines. Unlike medicines that actively create blood clots, tranexamic acid helps preserve clots that the body has already formed. It works by slowing the natural breakdown of fibrin, the protein mesh that stabilizes a blood clot, allowing the injured blood vessel more time to heal.

Why this is important

  • Supports the body's natural clot stabilization process.
  • Helps reduce unnecessary blood loss without initiating new clot formation.
  • Acts only on the fibrinolytic (clot breakdown) pathway.
  • Can be used in various situations where excessive bleeding is associated with increased fibrinolysis.

2. Why Timing of Administration Matters

The effectiveness of Trapic 500 mg Tablet depends not only on the prescribed dose but also on starting therapy at the appropriate time for the condition being managed. Early administration during an episode of excessive bleeding helps preserve newly formed clots before they break down prematurely. Delayed administration may reduce the medicine's overall benefit in some situations. Always follow the timing recommended by your healthcare professional.

Patient Tips

  • Follow the prescribed dosing schedule carefully.
  • Take each dose at evenly spaced intervals if multiple daily doses are prescribed.
  • Complete the recommended course even if bleeding begins to improve.
  • Do not change the dose or duration without consulting your healthcare professional.

3. Kidney Function and Individualized Dosing

Tranexamic acid is eliminated primarily through the kidneys. Reduced kidney function can increase medicine levels in the body, which is why healthcare professionals may recommend dose adjustments or additional monitoring in patients with renal impairment. This individualized approach helps optimize therapy while maintaining safety.

Patients Who May Need Additional Monitoring

  • Older adults with age-related decline in kidney function.
  • Individuals with chronic kidney disease.
  • Patients taking multiple medicines that require renal dose adjustments.
  • People with a previous history of urinary tract or kidney disorders.

4. Situations Where Healthcare Professionals May Consider Tranexamic Acid

Trapic 500 mg Tablet is widely used across different medical specialties because excessive bleeding can occur in a variety of clinical settings. Depending on the patient's condition, it may be prescribed for heavy menstrual bleeding, dental procedures, nosebleeds, or bleeding associated with certain surgical procedures. The exact indication, dose, and duration vary according to the clinical situation and should always be determined by a healthcare professional.

FAQs About TRAPIC 500MG TABLET

Q: What is Trapic 500 mg Tablet used for?

A: Trapic 500 mg Tablet is a prescription medicine containing tranexamic acid. It is used under medical supervision in conditions associated with excessive bleeding by helping stabilize blood clots.

Q: How should I take Trapic 500 mg Tablet?

A: Swallow the tablet whole with a glass of water. It can be taken with or without food. Take it exactly as prescribed by your healthcare professional.

Q: Can I take Trapic 500 mg Tablet with food?

A: Yes. Trapic 500 mg Tablet may be taken with or without food. Taking it after food may help reduce stomach discomfort in some people.

Q: What should I do if I miss a dose?

A: Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not take two doses together.

Q: Can I stop taking Trapic 500 mg Tablet once the bleeding improves?

A: No. Continue taking the medicine for the duration prescribed by your healthcare professional. Do not stop it early without medical advice.

Q: Is Trapic 500 mg Tablet suitable for elderly patients?

A: Yes, it may be prescribed for elderly patients. However, those with reduced kidney function or other medical conditions may require closer monitoring and, if necessary, dose adjustments.

Q: Can children take Trapic 500 mg Tablet?

A: Yes, it may be prescribed for elderly patients. However, those with reduced kidney function or other medical conditions may require closer monitoring and, if necessary, dose adjustments.

Q: Can I take other medicines while using Trapic 500 mg Tablet?

A: Inform your healthcare professional about all prescription medicines, over-the-counter products, vitamins, and herbal supplements you are taking, as some medicines may interact with tranexamic acid.

Q: How should Trapic 500 mg Tablet be stored?

A: Store the tablets in a cool, dry place away from direct sunlight and moisture. Keep them in their original packaging and out of the reach of children.

Q: Why are regular follow-up appointments important while taking Trapic 500 mg Tablet?

A: Follow-up appointments allow your healthcare professional to assess your response to therapy, review your overall health, monitor for any concerns, and determine whether any adjustments to your

References

1. KD. Tripathi. Drugs affecting blood and blood formation. Essentials of medical pharmacology. 8th Edition. 2019. Page – 676.

2. John M. Chauncey, Jerald S. Wieters. Tranexamic Acid. NIH National Library of Medicine, National center for biotechnology information. [Revised in January 2022] [Accessed on 26th June 2026] 

3. Johnny Cai, Jessica Ribkoff, Sven Olson, Vikram Raghunathan, Hanny Al-Samkari, Thomas G. DeLoughery, and Joseph J. Shatzel. The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. 2019 [Accessed on 26th June 2026] 

4. Amring Pharmaceuticals, Inc. Tranexamic Acid. NIH National Library of Medicine, DailyMed. [Revised in December 2020] [Accessed on 26th June 2026] 

5. Mercury pharma. Medsafe. Tranexamic acid film-coated tablets 500 mg. [Revised in September 2021] [Accessed on 26th June 2026] 

Useful Diagnostic Tests

  • Complete blood count
  • kidney function test
  • Bleeding time/clotting time
  • Urine analysis

Author Details

Written By Dr. R. Dinesh John Rajkumar - Pharm.D
Reviewed For Accuracy By Dr. Venkatesh Poludasu - MBBS
Last updated on 06 Mar 2023 | 09:16 AM(IST)
Lab updated