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Introduction About TRANCODOL LA INJECTION
TRANCODOL LA INJECTION contains Haloperidol which belongs to the group of medicines called Antipsychotics. It is used to manage illnesses that affect the way you think, feel or behave such as schizophrenia.
Symptoms of schizophrenia include feeling confused, seeing, hearing, feeling or smelling things that are not there, believing things that are not true, feeling unusually suspicious, feeling very excited, agitated, enthusiastic, impulsive or hyperactive, very aggressive, hostile or violent. TRANCODOL LA INJECTION is used in patients whose condition has previously been managed with oral route of the medicine.
Your doctor might want you to take several diagnostic tests before or during your management with TRANCODOL LA INJECTION such as ECG (electrocardiogram) or checking the levels of electrolytes such as magnesium or potassium in your blood.
TRANCODOL LA INJECTION is not recommended in patients having heart diseases, Parkinson’s disease, Lewy body dementia, progressive supranuclear palsy, or low potassium levels. Before receiving TRANCODOL LA INJECTION, inform your doctor if you have kidney problems, liver problems, thyroid problems, blood disorders, low blood pressure, depression, bleeding in the brain, prolactin-dependent tumors, or epilepsy.
TRANCODOL LA INJECTION should be used with caution in pregnant women only if the potential benefit justifies the potential risk to the baby. Caution must be exercised while using in breastfeeding women as small amounts of it may pass in breast milk. Avoid consumption of alcohol during management with TRANCODOL LA INJECTION, as it may make you feel sleepy and less alert.
TRANCODOL LA INJECTION is not recommended to use in children and adolescents under 18 years of age and should be used with caution in elderly patients. The most common side effects of receiving TRANCODOL LA INJECTION are feeling depressed, difficulty sleeping, constipation, dry mouth, or weight gain. Contact your doctor if any of the above symptoms worsen or doesn’t improve.
Uses Of TRANCODOL LA INJECTION
- it is used to manage schizophrenia
How TRANCODOL LA INJECTION Works
TRANCODOL LA INJECTION contains Haloperidol which is an antipsychotic that works by blocking certain receptors in the brain called dopamine (D2) receptors. This decreases the levels of dopamine, a nerve chemical. Thus, rebalancing dopamine to improve thinking, mood, and behavior.
How to use TRANCODOL LA INJECTION
TRANCODOL LA INJECTION will be given to you only by a doctor or a nurse into a muscle as an intramuscular injection. It must not be injected into a vein. Your doctor will decide the correct dose and duration of TRANCODOL LA INJECTION for you depending on your age, body weight, and disease condition.
Side Effects Of TRANCODOL LA INJECTION
Common
- depression
- difficulty sleeping or feeling sleepy
- constipation
- dry mouth or increased saliva
- problems having sex
- irritation, pain or collection of pus at the injection site
- weight gain
Uncommon
- abnormal muscle tension
- headache
- upward movement of the eyes
- uncontrollable fast eye movements
- blurred vision
Rare
Stop receiving TRANCODOL LA INJECTION and contact your physician immediately if you experience any of following side effects:
- neuroleptic malignant syndrome (signs include high fever, severe muscle stiffness, confusion, and loss of consciousness)
- heart problems such as irregular heartbeat, abnormally fast heartbeat, extra heartbeats
- extrapyramidal disorder (problems controlling movements of the body or limbs) (signs include movements of the mouth, tongue, jaw, and sometimes limbs, feeling restless or difficulty sitting, increased body movements, slow or reduced body movements, jerking or twisting movements, muscle tremors or stiffness, a shuffling walk, being unable to move, and lack of normal facial expression)
- severe allergic reaction (signs include a swollen face, lips, mouth, tongue, or throat, difficulty swallowing or breathing, and itchy rash (hives))
- blood clots in the veins, especially in the legs which can move to lungs
How To Manage Side Effects
Headache:
Try to take rest and don’t involve yourself in exertive activities. Rest in a quiet and dark room. Apply a pain-relieving balm on your forehead. Ask for your doctor’s advice if headache persists or worsen.
Constipation:
Eat plenty of foods enriched with fiber such as vegetables, fresh fruits, and cereals and drink plenty of water. Exercise more regularly. Ask for your doctor’s advice if constipation persists or worsen.
Dry mouth:
Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Ask for your doctor’s advice if dry mouth persists or worsen.
Warning & Precautions
Pregnancy
TRANCODOL LA INJECTION should be used with caution in pregnant women only if clearly advised by the doctor. If TRANCODOL LA INJECTION is received during third trimester it may cause muscle tremors, stiff or weak muscles, being sleepy or agitated, or problems in breathing or feeding in newborn babies. Consult your doctor before receiving TRANCODOL LA INJECTION.
Breastfeeding
TRANCODOL LA INJECTION should be used with caution in breastfeeding women as it may pass into breast milk. Consult your doctor before receiving it.
Driving and Using Machines
Do not drive or use machineries if you feel sleepy after receiving TRANCODOL LA INJECTION.
Alcohol
Avoid consumption of alcohol while receiving TRANCODOL LA INJECTION as it may make you sleepy, less alert.
Kidney
TRANCODOL LA INJECTION should be used with caution in patients with kidney diseases. Consult your doctor before receiving it.
Liver
TRANCODOL LA INJECTION should be used with caution in patients with liver diseases. Consult your doctor before receiving it.
Allergy
Do not receive TRANCODOL LA INJECTION if you are allergic to Haloperidol, Sesame oil, or any of the other ingredients of this medicine.
Heart Disease
TRANCODOL LA INJECTION is not recommended in patients having heart conditions like prolonged QT interval or any other problem with the heart rhythm, heart failure, or recently had a heart attack. TRANCODOL LA INJECTION should be used with caution in patients having other heart diseases such as slow heartbeat. Consult your doctor before receiving TRANCODOL LA INJECTION.
Others
TRANCODOL LA INJECTION is not recommended for use if you have:
- lack of awareness of things around you or unusually slow reactions
- Parkinson’s disease
- Lewy body dementia
- progressive supranuclear palsy (PSP)
- low levels of potassium in blood which is not being manageed
Before receiving TRANCODOL LA INJECTION, inform your doctor if you have:
- thyroid problems
- low blood pressure or dizziness while standing up or sitting
- low levels of magnesium or other electrolytes
- bleeding in brain or tendency to have a stroke
- history of blood clots or any of your family member has it
- depression
- high levels of prolactin or tumor such as breast-cancer
- epilepsy or ever had fits
Use in pediatrics:
TRANCODOL LA INJECTION is not recommended for use in children and adolescents below 18 years of age. Consult your child’s doctor for advice.
Use in geriatrics:
TRANCODOL LA INJECTION should be used with caution in elderly patients. Your doctor may adjust your dose depending upon your present condition, age, and body weight. Consult your doctor before receiving TRANCODOL LA INJECTION.
Interactions
A. Drug-Drug interactions:
Before receiving TRANCODOL LA INJECTION, inform your doctor if you are taking any of the following medicine:
- medicines used to manage heart problems (Ex. amiodarone, dofetilide, disopyramide, dronedarone, ibutilide, quinidine, verapamil, guanethidine, methyldopa, bepridil and sotalol)
- medicine used to manage depression (Ex. citalopram and escitalopram), anxiety or induce sleep (Ex. alprazolam or buspirone)
- medicines used to manage psychoses (Ex. levomepromazine, fluphenazine, perphenazine, pimozide, sertindole, prochlorperazine, promazine, thioridazine, trifluoperazine, triflupromazine, fluvoxamine, duloxetine, fluoxetine, paroxetine, nefazodone, sertraline, St John’s Wort (herbal), or venlafaxine, lithium, and ziprasidone)
- medicine used to manage bacterial infections (Ex. azithromycin, rifampicin, clarithromycin, erythromycin, levofloxacin, moxifloxacin, and telithromycin)
- medicine used to manage fungal infections (Ex. pentamidine, itraconazole, posaconazole or voriconazole)
- halofantrine (used to manage malaria)
- medicine used to manage nausea and vomiting (Ex. dolasetron, chlorpromazine, promethazine)
- medicine used to manage cancer (Ex. toremifene and vandetanib)
- medicine used to manage pain or drug addiction (Ex. methadone)
- medicine used to manage epilepsy (Ex. carbamazepine, phenobarbital, or phenytoin)
- medicine used to help you leave smoking (Ex. bupropion)
- medicine used to manage Cushing’s syndrome (Ex. ketoconazole)
- medicine used to manage human immunodeficiency virus or HIV (Ex. indinavir, ritonavir, or saquinavir)
- medicines used to manage severe allergic reactions (Ex. adrenaline)
- medicines used to manage attention deficit hyperactivity disorder (ADHD) (Ex. methylphenidate), Parkinson’s diseases (Ex. levodopa)
- medicines used as blood thinners (Ex. phenindione)
Overdosage:
TRANCODOL LA INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, inform your doctor immediately if you experience any unusual symptoms while receiving TRANCODOL LA INJECTION such as extrapyramidal reactions (problem controlling movements of the body), low blood pressure, and sedation.
Synopsis
| Drug | : | Haloperidol |
| Pharmacological Category | : | Antipsychotic |
| Therapeutic Indication | : | Schizophrenia |
| Dosage Forms | : | Tablet, Injection, Syrup, Liquid |
More Information
- Keep TRANCODOL LA INJECTION out of reach of children
- Store TRANCODOL LA INJECTION at a temperature, not more than 25°C
FAQs About TRANCODOL LA INJECTION
Can TRANCODOL LA INJECTION cause headaches?
Yes. Receiving TRANCODOL LA INJECTION can cause headache. Keep yourself hydrated by drinking more fluids such as water or electrolytes. If needed apply a pain-relieving balm on the forehead. Avoid consumption of alcohol. If the symptoms do not improve or persist, please consult your doctor for advice.
Is driving a car safe after receiving TRANCODOL LA INJECTION?
TRANCODOL LA INJECTION may impair the mental and/or physical abilities. Do not drive or operate any machines if you feel sleepy or have reduced alertness receiving TRANCODOL LA INJECTION. You can resume doing your activities as soon as you feel normal again.
Is TRANCODOL LA INJECTION safe for use in elderly patients?
TRANCODOL LA INJECTION should be used with caution in elderly patients specially those who suffer from dementia. Your doctor may adjust your dose depending upon your present condition, age and body weight. Some serious side effects have been reported in elderly patients having dementia. Consult your doctor before receiving TRANCODOL LA INJECTION.
Does TRANCODOL LA INJECTION affects fertility?
TRANCODOL LA INJECTION may affect and increase the levels of a hormone called ‘prolactin’, which may affect fertility in men and women. Talk to your doctor if you have any questions regarding this.
Can I stop receiving TRANCODOL LA INJECTION on my own?
Do not stop receiving TRANCODOL LA INJECTION until and unless you are told by your doctor to do so. Stopping management suddenly may cause your symptoms to return. Ask for your doctor’s advice if you wish to discontinue your management with TRANCODOL LA INJECTION.
Do I need to undergo any diagnostic tests before or while being managed with TRANCODOL LA INJECTION?
Your doctor might want you to take several diagnostic tests before or during your management with TRANCODOL LA INJECTION such as ECG (electrocardiogram) or checking the levels of electrolytes such as magnesium or potassium in your blood.
How is TRANCODOL LA INJECTION administered?
TRANCODOL LA INJECTION will be given by a doctor or nurse. It is for intramuscular use and is given as an injection deep into a muscle. A single dose of TRANCODOL LA INJECTION will normally last for 4 weeks. TRANCODOL LA INJECTION must not be injected into a vein. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and severity of disease condition.
References
1. KD. Tripathi. Antipsychotic and Antimanic Drugs. Essentials of medical pharmacology. Eighth edition. 2019. Page – 467
2. Ibrahem Hanafi, Subhi Arafat, Lin Al Zayed, Majd Sukkar, Abdullah Albeirakdar, Dima Krayem, and Adib Essali. Haloperidol (route of administration) for people with schizophrenia. NIH National Library of Medicine National Centre for Biotechnology. Pubmed Central. October 2017. [Accessed on 3rd September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485536/
3. Sajedur Rahman, Raman Marwaha. NIH National Library of Medicine National Centre for Biotechnology. Statpearls. Haloperidol. [Revised in July 2022]. [Accessed on 3rd September 2022] https://www.ncbi.nlm.nih.gov/books/NBK560892/
4. Keith Kleinman. Haloperidol. Science Direct. [Accessed on 3rd September 2022] https://www.sciencedirect.com/topics/medicine-and-dentistry/haloperidol
5. Janssen Pharmaceutica NV. Electronic Medicines Compendium (EMC). [Revised in April 2020] [Accessed on 3rd September 2022] https://www.medicines.org.uk/emc/files/pil.968.pdf
6. Janssen Pharmaceuticals. Haloperidol Injection. [Revised in November 2020] [Accessed on 3rd September 2022] https://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/HALDOL+Decanoate-pi.pdf
Useful Diagnostic Tests
- Electrocardiogram (ECG)
- Serum electrolytes
- EEG (Electroencephalogram)
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