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Introduction About TOBAGRAM D EYE OINTMENT
TOBAGRAM D EYE OINTMENT is a combination of Dexamethasone and Tobramycin which belongs to the group of medicines called Corticosteroids and Antibiotics respectively. It is used to manage inflammation and infection in the eyes/ears.
It also helps in reducing pain, redness, itching and/or burning or stinging sensation in the eyes or ears following surgery (such as cataract or corneal refractive surgery). It is typically used in conditions which involves the risk of both eye/ear inflammation and infection such as during injuries or post-surgery.
Use this medicine exactly as instructed by your physician. Misuse or overuse of this medicine may lead to unwanted side effects. If you wear soft contact lenses, remove the lens before applying TOBAGRAM D EYE OINTMENT and wait for at least 15 minutes before reinsertion. TOBAGRAM D EYE OINTMENT is suitable for use both in adults and in children aged 2 years and above.
Before using TOBAGRAM D EYE OINTMENT inform your doctor if you have severe viral or fungal eye infections. You must also inform your doctor if you have glaucoma, diabetes, joint pain, muscle problems, parkinsonism or any disorders that may cause eye tissue layer thinning as a precaution.
Do not use TOBAGRAM D EYE OINTMENT without consulting your doctor if you are pregnant or breastfeeding. The most common side effects of using TOBAGRAM D EYE OINTMENT are mild eye irritation or burning sensation, watery eyes, increased eye pressure and taste changes. Consult your doctor if any of these side effect worsens.
Uses Of TOBAGRAM D EYE OINTMENT
It is used in adults and in children (aged 2 years or above) to:
- Manage and manage infection and inflammation of eyes/ears
- Reduce pain, redness, itching or burning/stinging sensation following surgery in the eyes or ears
How TOBAGRAM D EYE OINTMENT Works
TOBAGRAM D EYE OINTMENT contains two medicines namely, Dexamethasone and Tobramycin. Dexamethasone is a steroid medication. It blocks the release of certain chemicals in the body (such as prostaglandins) that causes inflammation, redness and swelling. When applied topically on the eyes/ears, it reduces redness, soreness, pain, itching and swelling.
Tobramycin is an antibiotic. When applied topically on the eyes/ears, it kills the susceptible bacteria that causes infection. Collectively, this medicine reduces inflammation and infection of the eyes and ears.
How to use TOBAGRAM D EYE OINTMENT
Use TOBAGRAM D EYE OINTMENT as advised by your physician. It is for ophthalmic use only. Take the required quantity of the medicine on your fingertip and gently apply it on the affected eyes or ears.
If you wear soft contact lenses, remove the lens before applying TOBAGRAM D EYE OINTMENT and wait for at least 15 minutes before reinsertion.
Wash your hands before and after application. Leave a time gap of at least 5 minutes between this medicine and other eye medicines.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition.
Side Effects Of TOBAGRAM D EYE OINTMENT
Common
- mild irritation and burning sensation after application
- eye itching or discomfort
- watery eyes
- increased pressure within the eyes
Uncommon
- headache
- runny nose
- throat tightness
Rare
- eye redness
- blurred vision
- dry eyes
- eye surface inflammation
- bad taste
Stop using TOBAGRAM D EYE OINTMENT and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat, tongue causing difficulty in breathing or swallowing)
- severe skin reactions with blistering and peeling of skin
- severe eye pain, redness, irritation and vision changes
- signs of problems in adrenal gland (such as slowing growth, round face, swelling or weight gain around the face and the trunk, weakness, dizziness while standing up, fever, weight loss, anxiety, nausea, vomiting, diarrhoea, headache, sweating, changes in mood or personality and joint and muscle pains)
How To Manage Side Effects
Eye irritation:
Wash your eyes with plain cold water. Place an ice pack on your eye to ease the irritation. Avoid straining your eyes by looking at mobile phones, laptops or television. Wear protective eyeglasses while going outdoors.
Blurred vision:
Close your eyes and relax. Do not strain your eyes by looking at mobile phones, laptops or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
Warning & Precautions
Pregnancy
TOBAGRAM D EYE OINTMENT is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before using it.
Breastfeeding
TOBAGRAM D EYE OINTMENT is not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor before using it.
Driving and Using Machines
Do not drive or operate any heavy tools or machinery if you experience blurred vision after using TOBAGRAM D EYE OINTMENT.
Allergy
Do not use TOBAGRAM D EYE OINTMENT if you are allergic to Dexamethasone or Tobramycin.
Others
TOBAGRAM D EYE OINTMENT is not recommended for use if you:
- have severe viral or eye fungal infections
- have an eye infection that produces sticky pus
- have severe eye redness for unknown reasons
Before using TOBAGRAM D EYE OINTMENT inform your doctor if you:
- wear soft contact lenses
- have rheumatoid arthritis (joint pain and inflammation)
- have fluid build-up in the front portion of the eyes (Fuch’s dystrophy)
- recently had an eye surgery or corneal transplant
- have ulceration or wounds in the eye
- have diabetes
- have myasthenia gravis (severe muscle weakness)
- have parkinsonism (a brain disorder causing shakiness, involuntary movements)
Use in Pediatrics:
TOBAGRAM D EYE OINTMENT can be used in children and adolescents (aged 2 years or above). It is not recommended for use in children (aged below 2 years) due to lack of safety data. Therefore, consult your doctor before administration.
Use in Geriatrics:
TOBAGRAM D EYE OINTMENT should be used with caution in elderly patients. Therefore, consult your doctor before taking it.
Interactions
A. Drug - Drug interactions:
Before using TOBAGRAM D EYE OINTMENT, inform your doctor if you are taking any of the following medicines such as:
- medicines used to manage HIV infections such as ritonavir, cobicistat
- medicines used to manage glaucoma (such as timolol, pindolol, acetazolamide, brinzolamide)
- other eye medicines used to reduce inflammation
Overdosage:
If you or anyone else accidentally used excessive amount of this medicine, rinse your eyes or ears with warm water. If still irritation persists, consult your doctor for advice. If you or anyone else accidentally swallowed this medicine, consult your doctor immediately.
Synopsis
| Drug | : | Dexamethasone, Tobramycin |
| Pharmacological Category | : | Topical Corticosteroids, Aminoglycoside Antibiotics |
| Therapeutic Indication | : | Eye/Ear inflammation and infection |
| Dosage Forms | : | Eye drops, Eye Ointment, Ear Ointment |
More Information
- Keep TOBAGRAM D EYE OINTMENT out of reach of children
- Store TOBAGRAM D EYE OINTMENT at room temperature
- Do not use this medicine after 4 weeks of its opening, even if it contains some left-over medicine
FAQs About TOBAGRAM D EYE OINTMENT
Q: Can the use of TOBAGRAM D EYE OINTMENT cause blurred vision?
A: Yes. TOBAGRAM D EYE OINTMENT may cause blurred vision after application in some individuals, although not everybody gets them. If your vision becomes blur, close your eyes for some time and rest. Do not strain your eyes by looking at mobile phones, laptops or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
Q: Can I use other eye medicines while using TOBAGRAM D EYE OINTMENT?
A: Avoid concomittant use of any eye medicines while using TOBAGRAM D EYE OINTMENT without consulting your doctor.
Q: How to use TOBAGRAM D EYE OINTMENT?
A: Use TOBAGRAM D EYE OINTMENT as advised by your physician. It is for ophthalmic use only. Take the required quantity of the medicine on your fingertip and gently apply it on the affected eyes or ears. Wash your hands before and after application.
Q: What is the use of TOBAGRAM D EYE OINTMENT?
A: TOBAGRAM D EYE OINTMENT is a prescription medicine used to manage inflammation and/or infection in the eyes and ears.
Q: How long does it take for TOBAGRAM D EYE OINTMENT to work?
A: It may take around 10-15 minutes for TOBAGRAM D EYE OINTMENT to start showing its effects. However, this period may vary from person-to-person depending upon the dose that is administered.
Q: What are the side effects of TOBAGRAM D EYE OINTMENT?
A: The most common side effects of using TOBAGRAM D EYE OINTMENT are mild eye irritation or burning sensation, watery eyes, increased eye pressure and taste changes. Consult your doctor if any of these side effect worsens.
Q: Can I use TOBAGRAM D EYE OINTMENT while wearing contact lenses?
A: If you wear soft contact lenses, remove the lens before applying TOBAGRAM D EYE OINTMENT and wait for at least 15 minutes before reinsertion.
Q: Can I use TOBAGRAM D EYE OINTMENT without consulting my doctor?
A: No. TOBAGRAM D EYE OINTMENT is a prescription medicine which should be used only if prescribed by the physician. It is because, TOBAGRAM D EYE OINTMENT contains a steroid medicine, which may cause harmful side effects when used without proper medical supervision. Therefore, consult your doctor for advice.
Q: Can I drive or ride a bike after using TOBAGRAM D EYE OINTMENT?
A: Do not drive if you experience blurred vision after using TOBAGRAM D EYE OINTMENT.
Q: What if I miss a dose of TOBAGRAM D EYE OINTMENT?
A: If you missed a dose of TOBAGRAM D EYE OINTMENT, apply it as soon as you remember. However, if it is time for next dose, skip the missed dose and use the regular dose. Do not use a double dose of TOBAGRAM D EYE OINTMENT to compensate the missed dose.
Q: How TOBAGRAM D EYE OINTMENT works?
A: TOBAGRAM D EYE OINTMENT blocks the release of certain chemicals in the body (such as prostaglandins) that causes pain, inflammation and swelling in the eyes/ears. It also kills the susceptible bacteria that causes infection. Collectively, this medicine reduces inflammation and infection of the eyes/ears.
Q: Can I stop using TOBAGRAM D EYE OINTMENT once my symptoms subside?
A: No. Do not stop using this medicine without consulting your doctor as it may make your symptoms to re-appear. Therefore, use this medicine consistently for the duration instructed by your doctor to achieve better results.
References
1. KD. Tripathi. Sulfonamides, Cotrimoxazole and Quinolones. Aminoglycoside Antibiotics. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 289 & 749.
2. Ricardo Notivol, Donata Bertin, Dina Amin, Anna Whitling, Margaret Kennedy, Paul C. Cockrum. Comparison of topical tobramycin—dexamethasone with dexamethasone—neomycin—polymyxin and neomycin—polymyxin—gramicidin for control of inflammation after cataract surgery: Results of a multicenter, prospective, three-arm, randomized, double-masked, controlled, parallel-group study. Clinical Therapeutics. August 2004. [Accessed on 19th January 2023]. https://www.sciencedirect.com/science/article/abs/pii/S0149291804801139
3. Rayner Pharmaceuticals Limited. Dropodex 0.1% w/v Eye Drops, solution dexamethasone phosphate (as dexamethasone sodium phosphate). Electronics Medicines Compendium. [Revised in July 2022]. [Accessed on 19th January 2023]. https://www.medicines.org.uk/emc/files/pil.5132.pdf
4. Novartis Ireland Limited. Tobrasone/Tobradex 3 mg/ml/1 mg/ml eye drops, suspension tobramycin and dexamethasone. Electronics Medicines Compendium. [Revised in June 2022]. [Accessed on 19th January 2023]. https://www.medicines.org.uk/emc/files/pil.1324.pdf
5. Alcon Laboratories, Inc. TOBRADEX- tobramycin and dexamethasone suspension/ drops. Dailymed.com. [Revised in November 2022]. [Accessed on 19th January 2023]. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=22b59456-d26a-4f23-b052-3d73e00181eb
6. Rayner Pharmaceuticals Limited. Dropodex 0.1% w/v Eye Drops, solution dexamethasone phosphate (as dexamethasone sodium phosphate). Electronics Medicines Compendium. [Revised in July 2022]. [Accessed on 18th January 2023]. https://www.medicines.org.uk/emc/files/pil.5132.pdf
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