TIPANAT 20 Tablet 20's
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Introduction About TIPANAT 20 TABLET
TIPANAT 20 TABLET is used to manage adults with colon cancer or rectal cancer (colorectal cancer). It is used when the cancer has spread to other parts of the body. It is also used when other treatments have not worked or when other treatments are not suitable. TIPANAT 20 TABLET is a combination of Tipiracil and Trifluridine which belongs to the group of medicines known as Antineoplastic Agent which interferes with DNA in cancer cells to stop them from making new cancer cells. Tipiracil stops trifluridine from being broken down by enzymes before it can act.
Before taking TIPANAT 20 TABLET, inform your doctor if you have or had radiation treatment for your cancer, intolerance to galactose or the Lapp lactase deficiency or glucose-galactose malabsorption. TIPANAT 20 TABLET is not recommended for use in pregnant and breastfeeding women.
TIPANAT 20 TABLET is not suitable for the use in children and adolescents below 18 years of age. The most common side effects of TIPANAT 20 TABLET are weakness, feeling tired, decreased appetite, abdominal pain, indigestion and common cold. Consult your doctor if any of the above side effects persists for a longer duration.
Uses Of TIPANAT 20 TABLET
- Used to manage adults with colon cancer or rectal cancer (colorectal cancer)
How TIPANAT 20 TABLET Works
TIPANAT 20 TABLET is a combination of Trifluridine and Tipiracil. Trifluridine interferes with DNA in cancer cells to work against them from making new cancer cells. Tipiracil stops trifluridine from being broken down by enzymes before it can act.
How to use TIPANAT 20 TABLET
Take TIPANAT 20 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.
Side Effects Of TIPANAT 20 TABLET
Common
- weakness
- feeling tired
- decreased appetite
- abdominal pain
- indigestion
- common cold
- hair loss
- swelling of the gums, tongue, lips and/or mouth
- rash
- bleeding gums
- change in taste
Stop taking TIPANAT 20 TABLET and contact your physician immediately if you experience any of the following side effects:
- signs and symptoms of infections (fever, chills, sore throat, mouth ulcers), fatigue, easy bruising, bleeding of the nose, gums or mouth, tiny red spots on the skin, rash, shortness of breath, pale skin lips and nail beds
- stomach problems (nausea, vomiting and diarrhea that can cause you to become dehydrated)
- signs of infection such as sore throat, mouth ulcers or a fever
- feeling short of breath, tired or having pale skin
- unusual bruising or bleeding
- diarrhea
Warning & Precautions
Pregnancy
ContraindicatedTIPANAT 20 TABLET is not recommended for use in pregnant women as it may harm the unborn baby. Consult your doctor before taking the medicine.
Breastfeeding
Consult your doctorIf you are breastfeeding women or planning to breastfeed. You should not breastfeed while taking TIPANAT 20 TABLET and for one day after your last dose. Consult your doctor before taking the medicine.
Driving and Using Machines
Use with CautionIf you experience symptoms such as fatigue, dizziness or generally feeling unwell, which affects your ability to concentrate and react, while taking TIPANAT 20 TABLET you should not drive or use machines.
Kidney
Use with CautionTIPANAT 20 TABLET should be taken with caution in patients with kidney problems. Consult your doctor before taking the medicine.
Liver
Use with CautionTIPANAT 20 TABLET should be used with caution in patients with liver disease. Consult your doctor before taking the medicine.
Allergy
ContraindicatedDo not take TIPANAT 20 TABLET if you are allergic to Trifluridine or Tipiracil or any of the other ingredients of this medicine.
Use In Pediatrics
ContraindicatedTIPANAT 20 TABLET should not be administered in children and adolescents less than 18 years of age. Consult your doctor before taking.
Use In Geriatrics
Use with CautionTIPANAT 20 TABLET should be used with caution in elderly patients above 65 years of age or older as you may be at higher risk of side effects related to low blood cell levels.
Others
Before taking TIPANAT 20 TABLET, inform your doctor if you:
- have or had radiation treatment for your cancer
- have an intolerance to galactose or the Lapp lactase deficiency or glucose-galactose malabsorption
Interactions
A. Drug-Drug interactions:
Tell your healthcare professional about all the medicines you take, including prescription, non-prescription, vitamins, minerals, natural supplements or alternative medicines.
Overdosage:
If you think you have taken too much TIPANAT 20 TABLET, contact your healthcare professional, hospital emergency department or regional poison control centre immediately, even if there are no symptoms.
Synopsis
| Drug | : | Tipiracil, Trifluridine |
| Pharmacological Category | : | Thymidine phosphorylase inhibitor, Nucleoside metabolic inhibitor |
| Therapeutic Indication | : | Used to manage adults with colon cancer or rectal cancer (colorectal cancer) |
| Dosage Forms | : | Tablet |
More Information
Storage
- Keep TIPANAT 20 TABLET out of reach to children
- Store at a temperature, not more than 30°C
FAQs About TIPANAT 20 TABLET
Q: What is TIPANAT 20 TABLET used for?
A: TIPANAT 20 TABLET is used to manage adults with colon cancer or rectal cancer (colorectal cancer). It is used when the cancer has spread to other parts of the body. It is also used when other treatments have not worked or when other treatments are not suitable.
Q: Is TIPANAT 20 TABLET safe to use in pregnancy?
A: No. TIPANAT 20 TABLET is not recommended for use in pregnant women as it may harm the unborn baby. Consult your doctor before taking the medicine.
Q: Can TIPANAT 20 TABLET be used in patients with heart problems?
A: There is no proper data available for the use of TIPANAT 20 TABLET in patients with a history of cardiovascular conditions. Consult your doctor before taking TIPANAT 20 TABLET.
Q: Is TIPANAT 20 TABLET can be used in children?
A: No. TIPANAT 20 TABLET is generally not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before taking.
Q: Does TIPANAT 20 TABLET be taken by patients with liver and kidney disease?
A: TIPANAT 20 TABLET should be used with caution in patients having liver disease and kidney problems. Consult your doctor before taking TIPANAT 20 TABLET.
Q: Does TIPANAT 20 TABLET cause tiredness?
A: Yes. It may cause tiredness in some individuals, which is induced by this medicine are considered as one of the common side effects. If this side effects persists for a longer duration, consult your doctor for advice.
Q: How does TIPANAT 20 TABLET works?
A: TIPANAT 20 TABLET is a combination of Trifluridine and Tipiracil. Trifluridine interferes with DNA in cancer cells to work against them from making new cancer cells. Tipiracil stops trifluridine from being broken down by enzymes before it can act.
Q: How long should I use TIPANAT 20 TABLET?
A: You are recommended to use TIPANAT 20 TABLET until your doctor suggests you stop the medication as per the suggested course and duration. Do not stop the medication without the instructions of the doctor as it may lead to serious problems.
References
1. Taiho Pharma Canada, Inc. [Revised on January 23, 2018] [Accessed on September 12th, 2024] https://pdf.hres.ca/dpd_pm/00043592.PDF
2. Lonsurf. [Accessed on September 12th, 2024] https://www.lonsurf.com/
3. Les Laboratoires Servier. [Revised on December 14, 2020] [Accessed on September 12th, 2024] https://www.ema.europa.eu/en/documents/product-information/lonsurf-epar-product-information_en.pdf
Useful Diagnostic Tests
- Biopsy-Small Specimen (< 2Cm)
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