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Introduction About TILSTIGMIN 15MG TABLET
TILSTIGMIN 15MG TABLET contain Neostigmine which belongs to a group of medicine called Cholinergic drugs. It is mainly used for the management of myasthenia gravis (a chronic autoimmune disorder in which antibodies destroy the communication between nerves and muscle, characterised by weakness in the arm and leg muscles, double vision, trouble speaking and chewing).
TILSTIGMIN 15MG TABLET is also used to normalise intestinal movements and for the management of urinary retention after surgery. TILSTIGMIN 15MG TABLET is not recommended for use if you have blockage in your intestine or face difficulty urinating.
Before taking TILSTIGMIN 15MG TABLET tell your doctor if you have asthma, fits, stomach ulcer or Parkinson’s disease. TILSTIGMIN 15MG TABLET should be used with caution in pregnant women and breast-feeding women.
Your doctor will prescribe the right dose of TILSTIGMIN 15MG TABLET for your child depending on their age, body weight and disease condition. Consult your doctor if you experience any side effects or if any of the symptoms worsen or persist.
Uses Of TILSTIGMIN 15MG TABLET
- Manage myasthenia gravis
- Normalises intestinal movements
- Manage urinary retention after surgery
How TILSTIGMIN 15MG TABLET Works
TILSTIGMIN 15MG TABLET increases muscle strength by blocking the action of an enzyme in the body which blocks nerve impulses to muscles. By stopping this enzyme from working, it strengthens muscles and thus helps in easing of intestinal movements and urinary retention.
How to use TILSTIGMIN 15MG TABLET
Take TILSTIGMIN 15MG TABLET as advised by your physician. Swallow with a glass of water, do not crush or chew it. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of TILSTIGMIN 15MG TABLET
Rare
Stop taking TILSTIGMIN 15MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- allergic reaction (sudden wheeziness, trouble breathing, swelling of the eyelids, face or lips, rash or itching especially of your whole body)
How To Manage Side Effects
Skin rash:
Try to avoid hot showers because it may cause skin irritation. Avoid frequent contact and rubbing over the affected area. Use sunscreen and protective clothing when outdoors. If symptom persists, contact your doctor.
Warning & Precautions
Pregnancy
TILSTIGMIN 15MG TABLET should be used with caution in women who are pregnant or planning to become pregnant. Consult your doctor before taking it.
Breastfeeding
TILSTIGMIN 15MG TABLET should be used with caution in breastfeeding women. Consult your doctor before taking it.
Driving and Using Machines
Do not drive or operate any machines if you feel ill after taking TILSTIGMIN 15MG TABLET.
Allergy
Do not take TILSTIGMIN 15MG TABLET if you are allergic to Neostigmine or any of the other ingredients of this medicine.
Lungs
TILSTIGMIN 15MG TABLET should be used with caution in patients having asthma. Consult your doctor for advice.
Others
TILSTIGMIN 15MG TABLET is not recommended for use if you have:
- a blockage in your bowel which may cause vomiting, abdominal pain and swelling
- difficulty passing urine
Before taking TILSTIGMIN 15MG TABLET, inform your doctor if you have:
- stomach ulcer
- epilepsy (fits)
- Parkinson’s disease
- been told to have an irritability of the vagus nerve which may cause excessive contractions of the intestine
Use in Pediatrics:
Your doctor will prescribe the right dose of TILSTIGMIN 15MG TABLET for your child depending on their age, body weight and disease condition.
Interactions
A. Drug - Drug interactions:
Before taking TILSTIGMIN 15MG TABLET, inform your doctor if you are taking any of the following medicines:
- medicines used to make you feel insensitive to pain (Ex. halothane, cyclopropane)
- suxamethonium (used to relax muscle during surgery)
Overdosage:
If you or anyone else accidentally take too much of TILSTIGMIN 15MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are stomach cramps, diarrhoea, nausea, vomiting and increased production of saliva.
Synopsis
| Drug | : | Neostigmine |
| Pharmacological Category | : | Anticholinesterases |
| Therapeutic Indication | : | Myasthenia gravis |
| Dosage Forms | : | Tablet, Injection |
More Information
- Keep out of reach of children
- Store below 30°C
FAQs About TILSTIGMIN 15MG TABLET
What should I do if I forget to take a dose of TILSTIGMIN 15MG TABLET?
If you forget a dose of TILSTIGMIN 15MG TABLET, take it as soon as you remember. However, skip that dose if it's almost time for the next one. Do not take TILSTIGMIN 15MG TABLET two times to make up for the missed dose.
Can TILSTIGMIN 15MG TABLET be taken in pregnancy?
Please tell your doctor if you are or think you may be pregnant or are planning to become pregnant before taking TILSTIGMIN 15MG TABLET. Although there are no known untoward effects from taking this medicine, your doctor will advise the correct course of management.
Can TILSTIGMIN 15MG TABLET be stopped?
Continue taking TILSTIGMIN 15MG TABLET until your doctor tells you to stop, unless you experience any unwanted effects, worsening of your condition or any new symptoms. Call your doctor in such case.
Can TILSTIGMIN 15MG TABLET be used in asthma patients?
TILSTIGMIN 15MG TABLET should be used with caution in patients having lung disease called asthma. Consult your doctor for advice. Your doctor will determine a proper dose or select a suitable alternative management for you.
Can I take other medicines with TILSTIGMIN 15MG TABLET?
Before taking TILSTIGMIN 15MG TABLET, inform your doctor if you are taking, have taken or might take any other medicine, including prescription, over the counter or any herbal medicine, as these might lead to serious side effects by interacting with each other.
References
1. KD. Tripathi. Cholinomimetic Alkaloids. Essentials of medical pharmacology. Eighth edition. 2019. Page – 119.
2. Ji W, Zhang X, Liu J, et al. Efficacy and safety of neostigmine for neuromuscular blockade reversal in patients under general anesthesia: a systematic review and meta-analysis. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. November 2021. [Accessed on 2nd July 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667102/
3. Jie Luo , Shuting Chen , Su Min , Lihua Peng. Reevaluation and update on efficacy and safety of neostigmine for reversal of neuromuscular blockade. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. December 2018. [Accessed on 2nd July 2022]. https://pubmed.ncbi.nlm.nih.gov/30573962/
4. Pharmaserve Limited. Electronic Medicines Compendium (EMC). [Revised in January 2015] [Accessed on 2nd July 2022]. https://www.medicines.org.uk/emc/files/pil.2849.pdf
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