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Introduction About TIDE PLUS 5MG TABLET
TIDE PLUS 5MG TABLET is a fixed-dose combination of Spironolactone and Torsemide which belongs to the group of medicines called Diuretics. It is used to reduce fluid accumulation (oedema) in the body that is caused due to severe liver, kidney or heart problems. It can also be used to manage hyperaldosteronism (excessive secretion of aldosterone in the body) and resistant hypertension (high blood pressure that is not controlled by other medicines).
Before taking TIDE PLUS 5MG TABLET inform your doctor if you have any liver, kidney or heart problems. Avoid consumption of alcohol while taking TIDE PLUS 5MG TABLET as it may make you feel dizzy or faint even while changing posture.
Avoid consuming potassium rich diet or potassium supplements while taking TIDE PLUS 5MG TABLET, as it may further increase the levels of potassium in your body. TIDE PLUS 5MG TABLET is not recommended for use in pregnant or breastfeeding women due to increased risk of side effects.
TIDE PLUS 5MG TABLET may alters the levels of electrolytes in your body and may make you feel dizzy or tired very easily. To avoid this, your doctor would regularly monitor your serum electrolyte levels and may increase or decrease the dose of this medicine accordingly.
The most common side effects of [GBKEYWORD] are headache, dizziness, nausea, vomiting, tiredness, increased urination and impotence. Consult your doctor if any of the side effect bothers you.
Uses Of TIDE PLUS 5MG TABLET
It is used to manage:
- oedema caused due to severe liver, kidney or heart problems
- hyperaldosteronism (excessive secretion of aldosterone in the body)
- resistant hypertension (high blood pressure that is not controlled by other medicines)
How TIDE PLUS 5MG TABLET Works
TIDE PLUS 5MG TABLET contains two medicines namely spironolactone and torsemide. Both spironolactone and torsemide acts by removing the excess water and electrolytes (sodium and chloride) from the body in the form of urine which helps in reducing blood pressure. Additionally, spironolactone can manage the loss of potassium via urine and can block the release of certain chemicals in the kidneys (aldosterone) that causes endocrine problems.
How to use TIDE PLUS 5MG TABLET
Take TIDE PLUS 5MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking TIDE PLUS 5MG TABLET unless your doctor tells you to stop.
Side Effects Of TIDE PLUS 5MG TABLET
Common
- headache, dizziness
- nausea, vomiting
- general weakness
- increased urination
- excessive thirst
- impotence
- indigestion
Rare
Stop taking TIDE PLUS 5MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- irregular heartbeat, chest pain
- bleeding from the gut or diarrhoea
- hyperglycaemia (increased blood glucose levels causing excessive urination and thirst, fatigue, headache)
- hyperuricemia (increased uric acid levels in blood causing joint pain, redness, swelling and of joints)
- hypokalaemia (low blood potassium levels causing constipation, tiredness, muscle weakness, tingling and numbness)
- hypotension (low blood pressure causing fainting, tiredness, blurred vision, nausea)
- hypovolemia (loss of body fluids causing headache, dizziness, low blood pressure, weakness, drowsiness, confusion, loss of appetite and cramps)
- blood clot formation in the body
- skin rash
- rectal bleeding
- feeling faint
How To Manage Side Effects
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely if you feel dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Nausea And Vomiting
Take TIDE PLUS 5MG TABLET with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.
Warning & Precautions
Pregnancy
ContraindicatedTIDE PLUS 5MG TABLET is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.
Breastfeeding
ContraindicatedTIDE PLUS 5MG TABLET is not recommended for use in breast-feeding women. Therefore, consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or handle any heavy tools or machines if you experience dizziness, drowsiness, or blurred vision after taking TIDE PLUS 5MG TABLET.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking TIDE PLUS 5MG TABLET as it might make you feel dizzy or faint even when you change posture.
Kidney
ContraindicatedTIDE PLUS 5MG TABLET is not recommended for use in patients with moderate to severe kidney diseases (such as difficulty in passing urine or acute renal failure). Therefore, consult your doctor before taking it.
Liver
Consult your doctorTIDE PLUS 5MG TABLET is not recommended for use in patients liver diseases. It should be used with caution in patients with other liver problems. Therefore, consult your doctor before taking it.
Allergy
ContraindicatedDo not take TIDE PLUS 5MG TABLET if you are allergic to Torsemide, Spironolactone or sulfonylureas (Ex. glimepiride, glipizide).
Heart Disease
ContraindicatedTIDE PLUS 5MG TABLET is not recommended for use in patients with heart diseases (such as low blood pressure or abnormal heart rate). Therefore, consult your doctor before taking it.
Others
TIDE PLUS 5MG TABLET is not recommended for use if you:
- have high levels of potassium in your blood (hyperkalaemia)
- have Addison’s disease (deficiency of cortisol and aldosterone)
Use in paediatrics:
There is no proper information regarding the use of TIDE PLUS 5MG TABLET in children and adolescents (below 18 years). Therefore, consult your doctor before taking it.
Use in geriatrics:
TIDE PLUS 5MG TABLET should be used with caution in elderly patients. Therefore, consult your doctor before taking it.
Interactions
A. Drug - Drug interactions:
Before taking TIDE PLUS 5MG TABLET, inform your doctor if you are taking any of the following medicines such as:
- cholestyramine (a medicine used to control blood cholesterol levels)
- medicines that exert effects on heart function during emergency conditions (Ex. adrenaline, noradrenaline)
- probenecid (a medicine used to manage gout)
- lithium (a medicine used to manage mental illness)
- medicines used to reduce anxiety and to induce sleep (Ex. phenobarbital)
- corticosteroids (used to manage inflammation) Ex. methylprednisolone
- adrenocorticotropic hormone (used to manage cortisol deficiency)
- medicines used to relax muscles (Ex. tubocurarine)
- medicines used for pain relief (Ex. indomethacin, aspirin, morphine, fentanyl, codeine)
- cardiac glycosides (used to manage cardiac failure) Ex. digoxin
- carbenoxolone (a medicine used to manage ulcers)
- medicines used to manage bacterial infections Ex. trimethoprim, sulfamethoxazole, ceftriaxone, cefazolin, gentamycin, streptomycin
- cotrimoxazole (a medicine used to manage fungal infections)
- cisplatin (used to manage cancer)
- other potassium-sparing diuretics (used to manage fluid accumulation) Ex. eplerenone
- heparin and low molecular weight heparin (used to manage blood clots)
- potassium supplements (used to manage potassium deficiency) Ex. potassium chloride
- medicines used to manage high blood pressure such as ACE inhibitors, angiotensin II blockers or beta-blockers (Ex. enalapril, telmisartan, valsartan, propranolol)
- medicines used to manage diabetes (Ex. metformin, glimepiride)
B. Drug-Food interactions
Avoid foods rich in potassium such as bananas, dry fruits, lentils, dairy products, and salt substitutes such as potassium chloride.
Overdosage:
If you or anyone else accidentally took more TIDE PLUS 5MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include dehydration,
low blood pressure, decreased body fluids and electrolytes levels, low blood sodium levels, abnormal blood potassium levels, increased RBC count, drowsiness, mental confusion, erythematous rash, nausea, vomiting, dizziness, diarrhoea, or liver problems.
Synopsis
| Drug | : | Spironolactone, torsemide |
| Pharmacological Category | : | Potassium sparing diuretics, Loop diuretics |
| Therapeutic Indication | : | Oedema, hypertension, Hyperaldosteronism |
| Dosage Forms | : | Tablet |
More Information
- Keep TIDE PLUS 5MG TABLET out of reach of children
- Store TIDE PLUS 5MG TABLET at room temperature
FAQs About TIDE PLUS 5MG TABLET
Q: What is the use of TIDE PLUS 5MG TABLET?
A: TIDE PLUS 5MG TABLET is used to reduce fluid accumulation (oedema) in the body that is caused due to severe liver, kidney or heart problems. It can also be used to manage hyperaldosteronism (excessive secretion of aldosterone in the body) and resistant hypertension (high blood pressure that is not controlled by other medicines).
Q: Can I take TIDE PLUS 5MG TABLET daily?
A: Take TIDE PLUS 5MG TABLET as advised by your physician. Your doctor will evaluate your health condition and suggests you the number of doses that needs to be taken per day.
Q: What are the possible side effects of TIDE PLUS 5MG TABLET?
A: The most common side effects of [GBKEYWORD] are headache, dizziness, nausea, vomiting, tiredness, and increased urination. It may also cause impotence in men. Consult your doctor if any of the side effect bothers you. Also inform your doctor immediately if you experience irregular heartbeat, joint pain, muscle pain, extreme dizziness or fainting or rectal bleeding after taking TIDE PLUS 5MG TABLET.
Q: What is the best time to take TIDE PLUS 5MG TABLET?
A: It is advisable to take TIDE PLUS 5MG TABLET in the morning preferably after meals. This may avoid frequent urination at the night. However, consult your doctor regarding the time of administration of TIDE PLUS 5MG TABLET.
Q: How long does it take for TIDE PLUS 5MG TABLET to show the results?
A: It may take a few weeks for TIDE PLUS 5MG TABLET to show the results, and so take TIDE PLUS 5MG TABLET regularly as advised by your physician to see the optimum results.
Q: Can TIDE PLUS 5MG TABLET cause dizziness?
A: Yes, TIDE PLUS 5MG TABLET may cause dizziness due to the loss of fluids from the body. To avoid this, keep yourself hydrated by drinking plenty of fluids. Avoid driving or operating any tools or machines if you feel dizzy. Consult your doctor if you experience extreme dizziness.
Q: Can I consume alcohol while taking TIDE PLUS 5MG TABLET?
A: Avoid consumption of alcohol while taking TIDE PLUS 5MG TABLET as it might make you feel dizzy or faint even when you change posture.
Q: Do I have any food restrictions while taking TIDE PLUS 5MG TABLET?
A: Avoid food rich in potassium such as bananas, dry fruits, lentils, dairy products, and salt substitutes containing potassium while taking TIDE PLUS 5MG TABLET. It is because TIDE PLUS 5MG TABLET can reabsorb potassium in the kidneys, and so additionally consumption of potassium rich foods or supplements may further increase the levels of potassium in the blood.
Q: Do we need any laboratory investigations while taking TIDE PLUS 5MG TABLET?
A: Yes. TIDE PLUS 5MG TABLET may alter the electrolyte balance in your body, and make you feel tired or dehydrated very easily. To avoid this, your doctor would regularly monitor your serum electrolyte levels and increase or decrease the dose of this medicine accordingly.
Q: Can TIDE PLUS 5MG TABLET reduce my weight?
A: TIDE PLUS 5MG TABLET does not have any impact on reducing your weight. But, due to removal of excess water from the body, you may experience a slight reduction in body weight.
Q: Can I take TIDE PLUS 5MG TABLET to reduce my postpartum belly?
A: No. TIDE PLUS 5MG TABLET is not indicated for use in postpartum women. Do not take TIDE PLUS 5MG TABLET unless your doctor has prescribed it. It is not advisable to breastfeed while taking TIDE PLUS 5MG TABLET. Consult your doctor before taking TIDE PLUS 5MG TABLET.
Q: Can TIDE PLUS 5MG TABLET cause cancer?
A: No. Research does not suggest any risk of cancer while taking [GBNEYWORD]. If you are doubtful consult your doctor for advice.
Q: Can I take TIDE PLUS 5MG TABLET on my own?
A: No. TIDE PLUS 5MG TABLET is a prescription medicine. It should be used only when prescribed by a physician. Do not take TIDE PLUS 5MG TABLET on your own without consulting your doctor.
Q: Can TIDE PLUS 5MG TABLET affect sense of hearing?
A: Yes, some rare cases of hearing loss have been reported with the use of TIDE PLUS 5MG TABLET. This condition is often reversible after discontinuing the therapy. However, consult your doctor immediately if you experience any disturbances in the sense of hearing.
Q: Can the use of TIDE PLUS 5MG TABLET cause frequent urination?
A: Yes. TIDE PLUS 5MG TABLET may cause frequent urination. It tends to excrete the accumulated fluid from the body in the form of urine. As a result, you may experience an increase in tendency to urinate. If this bothers you, contact your doctor.
Q: Can the use of [GNKEYWORD] make me more tired?
A: Yes. TIDE PLUS 5MG TABLET may make you feel tired easily because it removes the excess fluids from the body. This reduces your energy levels and make you feel very tired. To avoid this, keep yourself hydrated by drinking plenty of fluids. If you experience extreme tiredness that hinders your daily activities, consult your doctor for advice.
References
1. K.D. Tripathi. Diuretics Essentials of pharmacology seventh edition, 2013 Page no – 581 and 587.
2. Juan Tamargo 1, Julian Segura, Luis M Ruilope. Diuretics in the treatment of hypertension. Part 2: loop diuretics and potassium-sparing agents. NIH. National Library of Medicine. National Centre for biotechnology information. Pubmed.gov. April 2014. [Accessed on 4th February 2023] https://pubmed.ncbi.nlm.nih.gov/24456327/
3. Cipla Ltd. Spironolactone/torsemide. Ciplamed.com. [Revised in April 2015]. [Accessed on 4th February 2023] https://www.ciplamed.com/content/dytor-plus-tablets
4. Torrent Pharmaceuticals Ltd. Spironolactone/torsemide [Revised in July 2016]. [Accessed on 4th February 2023] https://www.torrentian.com/pisheet/Upload/PI_Sheet/1818.pdf
5. La Renon Healthcare Pvt Ltd. Torvigress Plus. [Accessed on 4th February 2023] https://www.larenon.com/wp-content/uploads/2022/06/Torvigress-Torvigress-Plus-copy.pdf
6. Leeford Healthcare Pvt Ltd. Durite Plus 10. [Accessed on 4th February 2023] https://www.leeford.in/product/648/durite-plus-10
Useful Diagnostic Tests
- Kidney function test
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