Tide Plus 10mg Tablet 10'S

Introduction About TIDE PLUS 10MG TABLET

Tide Plus 10mg Tablet is a prescription medicine, combines Spironolactone and Torsemide, both of which belong to the group of Diuretics (water pills). It is mainly used to remove excess fluid from the body and reduce oedema (swelling) caused by conditions affecting the heart, liver, or kidneys.

This medicine is also helpful in managing hyperaldosteronism (excess aldosterone secretion) and resistant hypertension (high blood pressure not controlled by other drugs).

Tide Plus 10 Tablet is usually advised to be taken in the morning along with food to lower the chances of frequent urination at night and to reduce stomach discomfort. For best results, it is recommended to take the tablet at the same time every day, as this helps maintain a steady level of medicine in the body. The dosage and duration depend on your medical condition such as oedema, resistant hypertension, heart failure, liver disease, or kidney problems, and your doctor will decide the exact amount you need based on your health requirements. You should not adjust the dose on your own, and it is important to continue this medicine for as long as prescribed, even if your symptoms improve, to avoid a recurrence of fluid buildup, swelling, or high blood pressure.

Common side effects of Tide Plus 10 Tablet may include dizziness, frequent urination, headache, muscle pain, dehydration, diarrhea, nausea, electrolyte imbalance (especially potassium levels) and period pain. If any of these side effects continue or get worse, inform your doctor as they may suggest ways to manage or control them.

Before taking this medicine, it is important to discuss with your doctor if you have any existing liver problems, kidney disorders, are pregnant, or breastfeeding, and also share a list of all other medications, supplements, or herbal products you are taking since they may interact and affect how the medicine works.

Uses Of TIDE PLUS 10MG TABLET

• Oedema (fluid retention/swelling)
• Hyperaldosteronism (excess aldosterone secretion)
• Resistant hypertension (high blood pressure not controlled by other drugs)

Benefits of TIDE PLUS 10MG TABLET

1. Supports Fluid Balance Regulation: Tide Plus 10mg Tablet helps control and reduce excess fluid retention, easing swelling (oedema) related to heart, liver, and kidney conditions.
2. Helps Manage Resistant Hypertension: It contributes to better blood pressure control when other medications alone are insufficient.
3. Maintains Electrolyte Balance: By combining Spironolactone and Torsemide, it effectively reduces fluid without causing significant loss of potassium, supporting overall electrolyte stability.
4. Improves Cardiovascular Health: By lowering fluid overload, it reduces strain on the heart and supports improved cardiac function.
5. Enhances Daily Comfort: Reducing swelling and discomfort helps individuals maintain mobility and improve quality of life during conditions involving oedema and hypertension.

How TIDE PLUS 10MG TABLET Works

Tide Plus 10mg Tablet combines Spironolactone and Torsemide, two diuretics that work synergistically to help regulate fluid balance in the body by increasing urine output and reducing excess water retention.

Understanding the Mechanism of Action

Torsemide acts on the kidneys’ loop of Henle to inhibit sodium and chloride reabsorption, promoting increased urine production, while Spironolactone blocks aldosterone receptors, reducing sodium retention and supporting potassium conservation.

Key Ingredients and Their Role

• Torsemide: A loop diuretic that boosts the excretion of sodium, chloride, and water, aiding in rapid fluid reduction.
• Spironolactone: A potassium-sparing diuretic that balances electrolytes by antagonizing aldosterone, minimizing potassium loss.

Impact on Kidney Function

By enhancing sodium and water excretion, Tide Plus 10mg Tablet supports kidney function in managing fluid overload, while helping maintain electrolyte balance to reduce the risk of imbalances often seen in kidney or heart-related conditions.

Role in Fluid Regulation

The combined action of both diuretics facilitates effective control of oedema and fluid retention associated with heart failure, liver cirrhosis, and kidney disorders, leading to improved comfort and cardiovascular health.

How to use TIDE PLUS 10MG TABLET

How to Use Tide Plus 10mg Tablet

Tide Plus 10mg Tablet should be taken exactly as prescribed by your healthcare provider, usually once daily in the morning with food to minimize nighttime urination and reduce stomach discomfort. Swallow the tablet whole with a glass of water without crushing or chewing. Consistent daily intake at the same time supports steady therapeutic effects.

Recommended Dosage and Timing

The dosage of Tide Plus 10mg Tablet varies depending on your medical condition, age, and response to therapy. Your doctor will determine the optimal dose to help control symptoms such as fluid retention and high blood pressure. Follow the prescribed schedule without altering the dose or stopping the medication without medical advice.

Important Instructions for Tide Plus Tablet

• Take this medication with food to lessen stomach upset.
• Avoid alcohol, as it can increase dizziness or lightheadedness.
• Inform your doctor about any existing liver or kidney issues before starting the medication.
• Keep all scheduled medical appointments for monitoring electrolyte levels and kidney function.

Precautions During Administration

• Be cautious when engaging in activities requiring alertness, like driving, as dizziness or fatigue may occur.
• Rise slowly from sitting or lying positions to reduce the risk of lightheadedness.
• Inform your physician about all other medicines or supplements you are taking to avoid potential interactions.
• Pregnant or breastfeeding women should use this medication only after consulting their healthcare provider.

Side Effects Of TIDE PLUS 10MG TABLET

Like all medicines, Tide Plus 10mg Tablet may cause certain side effects in some individuals, although not everybody gets them.

The most common side effects of taking Tide Plus 10mg Tablet are:

• Dizziness
• Frequent urination
• Headache
• Muscle pain
• Dehydration
• Diarrhea
• Nausea
• Electrolyte imbalance (especially potassium levels)
• Period pain

When to consult your doctor?

• Irregular heartbeat or chest pain
• Bleeding from the gut or persistent diarrhea
• Hyperglycemia (increased blood glucose levels causing excessive urination, thirst, fatigue, and headache)
• Hyperuricemia (elevated uric acid causing joint pain, redness, and swelling)
• Hypokalemia (low potassium causing constipation, muscle weakness, tiredness, tingling, and numbness)
• Hypotension (low blood pressure causing fainting, blurred vision, nausea, and tiredness)
• Hypovolemia (loss of body fluids causing headache, dizziness, low blood pressure, weakness, confusion, loss of appetite, and cramps)
• Blood clot formation anywhere in the body
• Skin rash, itching, or hives
• Rectal bleeding or unexplained blood in urine
• Feeling faint or dizzy
• Signs of liver problems such as yellowing of the skin or eyes (jaundice)
• Signs of serious lowered blood platelets like unusual bleeding or bruising without injury
• Signs of pancreatitis such as severe abdominal or back pain
• Severe dehydration indicated by extreme weakness, confusion, or decreased urine output
• Sudden swelling of the face, lips, tongue, or throat indicating allergic reaction
• Difficulty breathing or shortness of breath
• Severe muscle weakness, cramps, or numbness

How To Manage Side Effects

Diarrhea

• Maintain Hydration: Drink plenty of fluids including water, clear broths, and oral rehydration salts to replace lost fluids and electrolytes.
• Eat Small, Frequent Meals: Stick to easy-to-digest foods like bananas, rice, applesauce, and toast (BRAT diet) to soothe your digestive system.
• Avoid Dairy, Fatty, or Spicy Foods: These can aggravate diarrhea and should be limited until recovery.
• Rest: Give your body time to heal by getting plenty of rest.
• Consult a doctor if Needed: Seek medical advice if diarrhea is severe, persistent, or accompanied by fever or blood in stools.

Dizziness Or Drowsiness

• Sit or Lie Down: If you feel dizzy, sit down, or lie down immediately to reduce falling. Keep your head still and close your eyes if needed.
• Hydrate: Dehydration can cause dizziness, so drink water or electrolyte-replenishing drinks like sports drinks.
• Avoid Sudden Movements: When standing or sitting, do so slowly to avoid triggering dizziness. Take your time when getting up.
• Eat Small, Regular Meals: Low blood sugar can cause dizziness, so eat small meals throughout the day and avoid skipping meals.
• Fresh Air: Sometimes dizziness can be alleviated by taking slow, deep breaths in a well-ventilated area.

Headache

• Rest in a Quiet, Dark Room: Find a calm, quiet space away from bright lights and loud noises. Lie down and close your eyes.
• Hydrate: Dehydration can contribute to headaches, so drink plenty of water.
• Apply a Cold or Warm Compress: A cold pack on your forehead may reduce pain, or a warm compress on your neck or shoulders can relieve tension.
• Over-the-Counter Pain Relief: You can take over-the-counter pain relievers like acetaminophen or ibuprofen if appropriate for you. Follow the recommended dosage.
• Practice Relaxation Techniques: Deep breathing exercises, meditation, or gentle stretching can help reduce stress and alleviate headache symptoms.

Nausea And Vomiting

• Rest and Relax: Find a quiet, comfortable place to rest and avoid sudden movements to help reduce nausea.
• Stay Hydrated: Sip small amounts of clear fluids like water, oral rehydration solutions, or herbal teas frequently to reduce dehydration.
• Eat Light, Bland Foods: When ready, try eating plain foods such as crackers, toast, or bananas that are easy on the stomach.
• Avoid Strong Odors and Spicy Foods: These can worsen nausea and should be avoided until symptoms improve.
• Use Over-the-Counter Remedies: Anti-nausea medications may help but consult your doctor before use.
• Practice Deep Breathing: Gentle breathing exercises can help calm your stomach and reduce discomfort.

Warning & Precautions

Pregnancy

Contraindicated

Tide Plus 10mg Tablet is not recommended for use by pregnant women, therefore, consult your doctor before using this medication if you are pregnant or planning to conceive.

Breastfeeding

Contraindicated

This medicine is not recommended for breastfeeding mothers. Consult your healthcare provider before use if you are nursing.

Driving and Using Machines

Use with Caution

Use caution when driving or handling heavy machinery, as Tide Plus 10mg Tablet may cause dizziness, drowsiness, or blurred vision. Avoid such activities if these symptoms occur.

Alcohol

Consult your doctor

Avoid alcohol while taking this medication, as it may increase dizziness or fainting, especially upon standing.

Kidney

Contraindicated

Contraindicated in patients with moderate to severe kidney problems, such as difficulty passing urine or acute renal failure. Always consult your doctor prior to use.

Liver

Consult your doctor

Use with caution if you have liver disease. Tide Plus 10mg Tablet is generally not recommended for patients with severe liver problems. Consult your healthcare professional before taking it.

Allergy

Contraindicated

Do not use Tide Plus 10mg Tablet if you are allergic to its components, including Torsemide or Spironolactone, or sulfonylurea medications such as glimepiride or glipizide.

Heart Disease

Contraindicated

Contraindicated in patients with certain heart diseases, including low blood pressure or abnormal heart rhythms. Always seek medical advice before starting this medication.

Use In Pediatrics

Consult your doctor

Safety and efficacy in children and adolescents under 18 years are not established. Consult your pediatrician before giving it.

Use In Geriatrics

Use with Caution

Use cautiously in elderly patients due to increased risk of adverse effects. Consult your doctor before taking it.

Other Warnings for TIDE PLUS 10MG TABLET

• Avoid use if you have hyperkalemia (high potassium levels in blood) or Addison’s disease.

Diet and Lifestyle Advice

1.What Are the Best Diet and Lifestyle Tips While Taking Tide Plus 10mg Tablet?

Drug - Drug interaction

1. Allopurinol
   • Interaction: Allopurinol may increase blood levels of azathioprine by inhibiting its metabolism.
   • Effects: Higher risk of severe myelosuppression, causing dangerous reductions in white blood cells.
   • Management: If co-administration is necessary, reduce AZORAN dose to one-quarter and closely monitor blood counts.
2. Lithium
   • Interaction: Tide Plus can reduce lithium excretion, increasing lithium levels.
   • Effects: Risk of lithium toxicity causing tremors, confusion, and neurological symptoms.
   • Management: Monitor lithium levels frequently and adjust dose accordingly.
3. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
   • Interaction: May reduce the diuretic and antihypertensive effects of Tide Plus.
   • Effects: Possible worsening of fluid retention and blood pressure control.
   • Management: Use NSAIDs cautiously, monitor blood pressure and renal function regularly.
4. ACE Inhibitors and ARBs
   • Interaction: Combined use can increase risk of hyperkalemia (high potassium levels).
   • Effects: Potential for cardiac arrhythmias and muscle weakness.
   • Management: Regularly monitor potassium levels and renal function.
5. Digoxin
   • Interaction: Tide Plus may alter potassium levels, affecting digoxin's therapeutic window.
   • Effects: Increased risk of digoxin toxicity with symptoms like nausea, vision changes, or arrhythmias.
   • Management: Monitor serum potassium and digoxin levels closely.
6. Potassium Supplements or Potassium-Sparing Diuretics
   • Interaction: Increased risk of hyperkalemia when combined.
   • Effects: May cause dangerous cardiac effects including arrhythmias.
   • Management: Avoid potassium supplements unless supervised by a healthcare professional; monitor potassium levels regularly.

Drug - Food interaction

1.Avoid potassium-rich foods: Patients taking Tide Plus 10mg Tablet should limit intake of potassium-rich foods such as bananas, dry fruits, lentils, dairy products, and salt substitutes containing potassium chloride to reduce the risk of hyperkalemia (high potassium levels).

2. Alcohol consumption: Alcohol intake should be avoided as it can intensify side effects like dizziness, fainting, and low blood pressure when taken with Tide Plus 10mg Tablet.

3.General diet advice: It is recommended to take the tablet with or just after meals to minimize stomach discomfort. A balanced, moderate salt diet is beneficial to support management outcomes.

4.Monitor blood sugar-affecting foods: For diabetic patients, maintain a consistent diet and closely monitor blood glucose levels, as Tide Plus may influence glucose regulation

Synopsis

More Information

FAQs About TIDE PLUS 10MG TABLET

References

1. K.D. Tripathi. Diuretics Essentials of pharmacology seventh edition, 2013 Page no – 581 and 587.

2. Juan Tamargo, Julian Segura, Luis M Ruilope. Diuretics in the management of hypertension. Part 2: loop diuretics and potassium-sparing agents. NIH. National Library of Medicine. National Centre for biotechnology information. Pubmed.gov. April 2014. [Accessed on 28th Aug 2025] 

3. La Renon Healthcare Pvt Ltd. Torvigress Plus. [Accessed on 28th Aug 2025] 

4. Leeford Healthcare Pvt Ltd. Durite Plus 10. [Accessed on 28th Aug 2025] 

Useful Diagnostic Tests

• Kidney Function Test (KFT)
• Electrolytes Serum/ Electrolytes Profile
• Glomerular Filtration Rate (Gfr)
• Creatinine Clearence Test
• Urine Culture

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Venkatesh Poludasu - MBBS

Last updated on 29 Aug 2025 | 02:56 PM(IST)