Abbott India Ltd

Thyronorm 50mcg Tablet 120'S

Hypothyroidism
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    Introduction About THYRONORM 50MCG TABLET

    Thyronorm 50mcg Tablet contains Levothyroxine Sodium, a synthetic thyroid hormone that supplements the body's natural hormone when the thyroid gland is underactive (hypothyroidism). It helps regulate metabolism, energy production, and overall physiological balance. 

    THYRONORM 50MCG TABLET is not recommended for use if you have unmanageed hyperthyroidism, subclinical or overt thyrotoxicosis, adrenal insufficiency, or pituitary insufficiency. Consult your doctor before taking it.

    THYRONORM 50MCG TABLET should be used with caution in patients with coronary heart disease such as acute myocardial infarction, acute myocarditis, acute pancarditis, angina pectoris, and hypertension. It  can be used safely in pregnant and breastfeeding women and requires dose adjustment.

    Common side effects are increased appetite, weight variations, headache, vomiting, diarrhea, changes in the menstrual cycle, fever, sensitivity to heat, cramps, and mood swings. Consult your doctor if any of the side effects worsen.

    Uses Of THYRONORM 50MCG TABLET

    Benefits of THYRONORM 50MCG TABLET

    • Supports normal thyroid hormone levels essential for metabolic functions
    • Helps alleviate symptoms like fatigue, weight gain, and muscle weakness associated with low thyroid hormone
    • Promotes balanced energy and mood stability
    • Plays a crucial role in growth and development for affected individuals

    How THYRONORM 50MCG TABLET Works

    • Levothyroxine is a synthetic form of thyroxine (T4), a natural thyroid hormone.
    • After oral administration, levothyroxine is absorbed primarily in the small intestine.
    • In peripheral tissues, T4 is converted into the active hormone triiodothyronine (T3) by deiodination.
    • T3 enters the cell nucleus and binds to thyroid hormone receptors.
    • This hormone-receptor complex modulates DNA transcription and protein synthesis essential for normal cellular metabolism.
    • These actions increase basal metabolic rate, stimulate gluconeogenesis, protein synthesis, and promote glycogen mobilization.
    • Levothyroxine thus restores deficient thyroid hormone levels and supports metabolic and physiological homeostasis.
    • The liver and kidneys play a key role in the metabolism and elimination of T4 and T3.

    How to use THYRONORM 50MCG TABLET

    Recommended Dosage of Thyronorm 50mcg

    • Typical starting dose ranges from 25 to 50 mcg once daily, adjusted individually based on thyroid function tests and patient response.
    • The dose can vary between 25 to 200 mcg daily depending on severity and clinical monitoring.

    When to Take Thyronorm: Timing with Meals

    • Take Thyronorm on an empty stomach, ideally first thing in the morning.
    • Wait at least 30 to 60 minutes before eating breakfast or drinking tea/coffee.
    • Avoid food, milk, or other medications during this waiting period for optimal absorption.

    Important Administration Tips for Thyronorm Tablet

    • Swallow the tablet whole with a full glass of water; do not crush or chew.
    • Maintain consistent timing daily to ensure stable hormone levels.
    • Separate Thyronorm dosing by at least 4 hours from antacids, calcium, iron, and some cholesterol-lowering medications to avoid interactions.
    • Regular blood testing is essential for dose adjustment and monitoring.

    Duration and Frequency of Thyronorm Use

    • Thyronorm is usually taken once daily, preferably in the morning.
    • Therapy is often lifelong for hypothyroidism management.
    • Do not discontinue without consulting your healthcare provider, as symptoms may recur.

    Thyronorm Tablet and Food: What You Should Know

    • Food and certain beverages can reduce the absorption and efficacy of Thyronorm.
    • Taking the tablet on an empty stomach ensures maximum bioavailability.
    • Be aware of medications and supplements that can interfere with Thyronorm absorption and consult your doctor.

    What if I forgot to take THYRONORM 50MCG TABLET

    • Take the missed dose as soon as you remember if it is not close to the time for the next dose.
    • Skip the missed dose if the next dose is near; do not double-dose to compensate.

    Overdose

    • If you or anyone else accidentally took more THYRONORM 50MCG TABLET, consult your doctor immediately or visit the nearby hospital.
    • Overdosage may cause hyperthyroidism, and symptoms include agitation, confusion, irritability, hyperactivity, headache, sweating, mydriasis, fast heartbeat, irregular heartbeat, fast breathing, fever, increased bowel movements, and fits.
    • Psychiatric symptoms associated with hyperthyroidism may also occur, including affectability, fatigue, anxiety, and nervousness.
    • In severe cases, it causes a thyrotoxic crisis and leads to seizures, cardiac arrhythmias, heart failure, and coma.

    Side Effects Of THYRONORM 50MCG TABLET

    Common

    • Increased appetite
    • Weight variations
    • Headache
    • Vomiting, diarrhoea
    • Changes in the menstrual cycle
    • Fever
    • Sensitivity to heat
    • Cramps and mood swings

    How To Manage Side Effects

    Diarrhea

    Drink lots of fluids, such as water or fruit juices, to keep yourself hydrated. Do not take any medicine on your own to manage diarrhea. Contact your doctor if your diarrhea does not improve.

    Headache

    Rest and relax. Drink plenty of fluids, such as water or ORS (Oral Rehydrating Solution), and apply a pain-relieving balm to the head if necessary. Contact your doctor if your headache does not improve.

    Warning & Precautions

    Pregnancy

    Consult your doctor

    THYRONORM 50MCG TABLET can be used for women who are pregnant or are planning conception.  consult your doctor before taking it.

    Breastfeeding

    Consult your doctor

    THYRONORM 50MCG TABLET can be used for breastfeeding women. Consult your doctor before taking it.

    Driving and Using Machines

    Use with Caution

    THYRONORM 50MCG TABLET does not have any influence on the ability to drive or operate any machine.

    Kidney

    Consult your doctor

    THYRONORM 50MCG TABLET does not have any significant effect on patients with kidney disease. Consult your doctor before taking it.

    Liver

    Use with Caution

    THYRONORM 50MCG TABLET should be used with caution in patients with liver disease due to impaired metabolism. Consult your doctor before taking it.

    Allergy

    Contraindicated

    Do not take THYRONORM 50MCG TABLET if you are allergic to thyroxine or any other ingredients in this medicine.

    Heart Disease

    Use with Caution

    THYRONORM 50MCG TABLET should be used with caution in patients with coronary heart disease such as acute myocardial infarction, acute myocarditis, acute pancarditis, angina pectoris, and hypertension. Consult your doctor before taking it.

    Use In Pediatrics

    Contraindicated

    THYRONORM 50MCG TABLET is not recommended for use in children and neonates under 2 years of age. Consult your doctor before taking it.

    Use In Geriatrics

    Use with Caution

    THYRONORM 50MCG TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking it.

    Other Warnings for THYRONORM 50MCG TABLET

    Before taking THYRONORM 50MCG TABLET, inform your doctor if you:

    • Have severe or chronic hypothyroidism
    • Have a history of thyroid cancer
    • Have diabetes mellitus or insipidus
    • Have pituitary and/or adrenocortical insufficiency
    • Have thyroid autonomy
    • Have secondary hypothyroidism or panhypopituitarism
    • Have a history of fits
    • Have myxoedema
    • Have malabsorption syndrome

    Who should not take THYRONORM 50MCG TABLET

    THYRONORM 50MCG TABLET is not recommended for use if you:

    • Have unmanageed hyperthyroidism
    • Have unmanageed subclinical or overt thyrotoxicosis
    • Have unmanageed adrenal insufficiency
    • Have unmanageed pituitary insufficiency

    Drug - Drug interaction

    • Antacids, Calcium, and Iron Supplements: These can reduce absorption of Thyronorm if taken simultaneously. Maintain at least a 4-hour gap between Thyronorm and these supplements for best effectiveness.
    • Cholestyramine, Colesevelam, Colestipol: These cholesterol-lowering agents may bind to levothyroxine and reduce its absorption. Separate dosing by several hours.
    • Antiepileptic Drugs (e.g., Phenytoin, Carbamazepine): May increase metabolism of levothyroxine, potentially lowering its effect, requiring dose adjustment.
    • Oral Contraceptives and Estrogens: Can reduce levothyroxine effectiveness; dose modifications may be needed.
    • Warfarin and Other Blood Thinners: Levothyroxine can enhance the anticoagulant effect; monitoring is essential.
    • Diabetic Medications: Thyronorm may alter blood sugar control; dose adjustments of antidiabetic drugs might be necessary.
    • Rifampicin and Protease Inhibitors (e.g., Ritonavir): Can induce metabolism of levothyroxine, reducing its efficacy.
    • St. John's Wort (Herbal Medicine): May reduce thyroxine levels by inducing liver enzymes.
    • Food Interactions: Take Thyronorm on an empty stomach 30-60 minutes before breakfast; food and caffeine may decrease absorption.
    • Alcohol: Generally considered safe but moderation and consultation with a doctor are advised.
    • Other Medications: Always inform your healthcare provider about any other medications (prescribed, over-the-counter, or supplements) to avoid potential interactions.

    Close monitoring by your healthcare provider is important while on Thyronorm, especially when starting or stopping interacting medications.

    Synopsis

    Drug :   Thyroxine
    Pharmacological Category :   Thyroid Hormones
    Therapeutic Indication :   Hypothyroidism           
    Dosage Forms :   Tablet

    More Information

    Did you know?

    • Levothyroxine, the active ingredient in Thyronorm, is one of the most widely prescribed medications worldwide for managing hypothyroidism, helping millions maintain normal metabolism and energy balance.
    • Despite being a synthetic hormone, levothyroxine closely mimics the natural thyroid hormone thyroxine (T4) and relies on the body's conversion to triiodothyronine (T3) to exert its effects at the cellular level.
    • Proper timing of Thyronorm dosing taking it on an empty stomach and waiting before meals can significantly impact its absorption and effectiveness.
    • Patients on levothyroxine therapy regularly monitor thyroid hormone levels through blood tests to ensure optimal dosing and avoid side effects.
    • Drug interactions with supplements like calcium and iron, or medications such as antacids and anticonvulsants, can affect levothyroxine absorption, requiring careful management and dose adjustments.
    • Levothyroxine therapy may continue lifelong for many individuals, but with appropriate medical follow-up, it substantially improves quality of life and metabolic health.

    Comparison of Thyronorm 50mcg Tablet with similar levothyroxine sodium products commonly available in the market:

    Attribute

    Thyronorm 50mcg Tablet

    Eltroxin 50mcg Tablet

    Euthyrox 50mcg Tablet

    Active Ingredient

    Levothyroxine Sodium

    Levothyroxine Sodium

    Levothyroxine Sodium

    Dosage Strength

    50 mcg

    50 mcg

    50 mcg

    Indications

    Hypothyroidism, Thyroid hormone replacement

    Hypothyroidism, Thyroid hormone replacement

    Hypothyroidism, Thyroid hormone replacement

    Bioavailability

    Comparable

    Comparable

    Comparable

    Manufacturing Quality

    Indian pharmaceutical standards

    Indian pharmaceutical standards

    European pharmaceutical standards

    Price Range

    Cost-effective, widely available

    Slightly higher, brand recognition

    Mid-range, imported product

    Packaging

    30/120 tablets per pack

    30 tablets per pack

    30/100 tablets per pack

    Patient Preference

    Often preferred for affordability

    Preferred for consistent quality

    Trusted for European manufacturing

    Storage Instructions

    Store in cool, dry place

    Store below 25°C, avoid moisture

    Store below 25°C, protect from light

    FAQs About THYRONORM 50MCG TABLET

    Q: What is the use of THYRONORM 50MCG TABLET?

    A: THYRONORM 50MCG TABLET is used in the management of thyroid deficiency (hypothyroidism). It replaces the deficient levels of a hormone called thyroxine in the body that is responsible for maintaining normal functioning of thyroid gland.

    Q: What does thyroxine do to our body?

    A: Thyroxine (T4) is a hormone produced by the thyroid gland, responsible for regulating metabolism. It helps maintain a balance between energy production and expenditure, regulates body temperature, heart rate, blood pressure, supports growth in children, maintains normal brain functions and enhances the absorption of nutrients taken through diet.

    Q: Can I take THYRONORM 50MCG TABLET when I am diabetic?

    A: Inform your doctor before taking THYRONORM 50MCG TABLET if you have diabetes. Studies have shown that thyroxine has an influence in increasing blood sugar levels and can interfere with the effects of antidiabetic medicines. Your healthcare provider will monitor your thyroid function regularly and adjust your thyroxine dosage as needed. Regular check-ups and communication with your healthcare team are crucial for managing both diabetes and thyroid conditions effectively.

    Q: Can I use contraception while taking THYRONORM 50MCG TABLET?

    A: Contraceptive pills (Birth control pills) may make THYRONORM 50MCG TABLET less effective. Therefore, it is better to consult your doctor before taking contraceptive pill. Your doctor might suggest a suitable contraceptive agent or alternative birth control methods.

    Q: How and when to take THYRONORM 50MCG TABLET?

    A: Take THYRONORM 50MCG TABLET as advised by your doctor. It should be taken orally preferably before breakfast or as a first meal of the day. Swallow the medicine with plenty of water.

    Q: How long should I take THYRONORM 50MCG TABLET?

    A: Take THYRONORM 50MCG TABLET as long as your doctor prescribes it to you. Hypothyroidism is a chronic condition and long-term management with medicines are essential. Do not stop taking the medicine, as it could make your symptoms re-appear.

    Q: Is THYRONORM 50MCG TABLET good for thyroid gland?

    A: THYRONORM 50MCG TABLET replaces your body with sufficient levels of thyroid hormones (T4-thyroxine) which helps to maintain healthy metabolism, growth and brain function.

    Q: What is a normal TSH levels in blood?

    A: Research suggest that, in general, the typical reference range for TSH is around 0.4 to 4.0 mIU/L.

    Q: Is THYRONORM 50MCG TABLET safe in pregnancy?

    A: It is safe for use during pregnancy. Clinical studies have shown low risk or no harm to the growing baby. However, it is better to inform your doctor about your pregnancy as a precaution.

    Q: What are the side effects of taking THYRONORM 50MCG TABLET?

    A: The most common side effects of taking THYRONORM 50MCG TABLET are increased appetite, weight increase or decrease, headache, vomiting, diarrhea, changes in the menstrual cycle, fever, sensitivity to heat, cramps, and mood swings. Consult your doctor if any of the side effects worsen.

    Q: What is the best time to take THYRONORM 50MCG TABLET?

    A: Take it in the morning on an empty stomach at least half an hour before breakfast or as directed by the physician. Swallow the medicine with a glass of water. Do not chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition.

    Q: Who should not take THYRONORM 50MCG TABLET?

    A: It is not recommended for use if you have elevated blood thyroid levels, subclinical or overt thyrotoxicosis (increased levels of circulating thyroid hormones), improper functioning of adrenal glands (adrenal insufficiency) or pituitary gland (pituitary insufficiency).

    References

    1. KD. Tripathi. Thyroid hormones and thyroid inhibitors. Essentials of medical pharmacology. Eight edition. 2019. Page-273.

    2. Mateo RCI, Hennessey JV. Thyroxine and treatment of hypothyroidism: seven decades of experience. Endocrine. 2019. [Accessed on 11th November 2025] 

    3. GlaxoSmithKline Pharmaceuticals Limited. Thyroxine. [Revised in June 2023] [Accessed on 11th November 2025] 

    4. Thyroxine sodium. Leeford Healthcare Ltd. [Accessed on 11th November 2025] 

    5. Drug bank. Levothyroxine. [Accessed on 11th November 2025] 

    Author Details

    Written By Dr. Janet.C - Pharm.D
    Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)
    Last updated on 12 Jul 2024 | 04:50 PM(IST)
    Lab updated