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Introduction About THRIZE TABLET
THRIZE TABLET is a combination of Bromelain, Rutoside, and Trypsin, which belongs to the group of medicines called Proteolytic enzymes and Flavonoids, respectively. It is used in the management of pain and inflammation associated with osteoarthritis, rheumatoid arthritis, gout, joint issues related to inflammation, pain and swelling of joints, swelling associated with surgical wounds, pulmonary edema, ulcerative colitis, sports and accidental injuries, muscular cramps and spasms, tendinitis, bursitis, dental extraction, sinusitis, bronchitis, and rhinitis.
Prior to starting the management with THRIZE TABLET, your doctor might want you to take several diagnostic tests to understand your existing condition and to safely use this medicine to manage the risk of any unusual effects.
THRIZE TABLET is not recommended for use in patients with hemophilia (a disorder in which blood doesn't clot normally), liver or kidney disorders, or patients undergoing haemodialysis. THRIZE TABLET should be taken with caution in patients with any bleeding disorders and heart disease.
THRIZE TABLET is not recommended for use in pregnant and breastfeeding women. There is no data on the use of THRIZE TABLET in children or elderly patients; hence, always consult your doctor for advice before taking this medicine.
The most common side effects of taking THRIZE TABLET are nausea, diarrhea, stomach upset, tiredness, dry mouth, and skin rash. Consult your doctor if any of the side effects worsen.
Uses Of THRIZE TABLET
Used in the management of pain and inflammation associated with the following:
- Osteoarthritis, rheumatoid arthritis, gout
- Joint issues related to inflammation
- Pain and swelling of joints
- Swelling associated with surgical wounds
- Pulmonary edema
- Ulcerative colitis
- Sports and accidental injuries
- Muscular cramps and spasms
- Tendinitis and bursitis
- Dental extraction
- Sinusitis, bronchitis, and rhinitis
How THRIZE TABLET Works
THRIZE TABLET helps in managing pain and inflammation associated with various conditions where bromelain and trypsin are protease enzymes that decrease inflammation by inhibiting the substances that are responsible for it called proinflammatory prostaglandins. It also influences blood clotting by increasing the activity of a protein called fibrinogen. Rutoside is a flavonoid that works by enhancing the strength of blood vessels and decreasing their ability to break down.
How to use THRIZE TABLET
Take THRIZE TABLET as advised by your physician. Swallow the medicine with enough water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of THRIZE TABLET for you depending on your age, body weight, and disease condition.
Side Effects Of THRIZE TABLET
Common
- Stomach upset
- Diarrhoea
- Dizziness, headache
- Dry mouth
- Tiredness
- Nausea, indigestion
- Constipation
- Skin rash
Rare
- Allergic reactions
How To Manage Side Effects
Constipation
Take fiber-rich foods in your diet, such as fresh fruits, vegetables, and whole grain cereals, and drink plenty of fluids. Exercise regularly (such as walking) and stay active. Consult your doctor if the symptom does not improve.
Diarrhea
Drink a lot of fluids, such as water or fruit juices, to keep yourself hydrated. Do not take any medicine on your own to manage diarrhea. Consult your doctor if the symptom does not improve.
Dry Mouth
Sip water and other sugar-free liquids regularly. Do not use mouthwashes that contain alcohol because they can make your mouth dry; use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.
Headache
Rest and relax. Drink plenty of fluids, such as water or electrolytes. Apply a pain-relieving balm on the forehead if required. Do not consume too much alcohol. Consult your doctor if the symptom does not improve.
Tiredness
Drink plenty of fluid, eat a balanced diet, and frequent meals. Do regular minimal exercise and follow a regular sleep schedule. Consult your doctor if the symptom does not improve.
Warning & Precautions
Pregnancy
ContraindicatedTHRIZE TABLET is not recommended for use in pregnant women. Consult your doctor before taking THRIZE TABLET.
Breastfeeding
ContraindicatedTHRIZE TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking THRIZE TABLET.
Alcohol
ContraindicatedAvoid consumption of alcohol while taking THRIZE TABLET.
Kidney
ContraindicatedTHRIZE TABLET is not recommended for use in patients with kidney disorders and in patients undergoing haemodialysis. Consult your doctor before taking THRIZE TABLET.
Liver
ContraindicatedTHRIZE TABLET is not recommended for use in patients with liver disorders. Consult your doctor before taking THRIZE TABLET.
Allergy
ContraindicatedDo not take THRIZE TABLET if you are allergic to Bromelain, Rutoside, and Trypsin.
Heart Disease
Use with CautionTHRIZE TABLET should be used with caution in patients with heart disease. Consult your doctor before taking it.
Others
THRIZE TABLET is not recommended for use if you:
- Have hemophilia (a disorder in which blood doesn't clot normally)
Before taking THRIZE TABLET, inform your doctor if you have:
- Any other bleeding disorder
Interactions
A. Drug-Drug Interactions:
Before taking THRIZE TABLET, inform your doctor if you are taking any of the following medicines:
- Digoxin (used to manage heart problems)
- Ramipril (used to manage high blood pressure)
Overdosage:
If you or anyone else accidentally take too much of THRIZE TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Bromelain, Rutoside, Trypsin |
| Pharmacological Category | : | Proteases, Flavonoids, and Proteolytic enzymes |
| Therapeutic Indication | : | Pain and inflammation associated with various conditions |
| Dosage Forms | : | Tablet, Capsule |
More Information
Storage
- Keep THRIZE TABLET out of reach of children
- Store below 25°C
FAQs About THRIZE TABLET
Q: Does THRIZE TABLET cause stomach disturbances?
A: Yes, THRIZE TABLET can cause side effects like vomiting, nausea, diarrhea, indigestion, and stomach bloating. Do not take any medication on your own to manage the specific symptom. Consult your doctor if any of the side effects worsen or bother you.
Q: Can THRIZE TABLET be used in patients with kidney problems?
A: THRIZE TABLET is not recommended for use in patients with kidney disorders and in patients undergoing haemodialysis. Consult your doctor before taking it.
Q: Is THRIZE TABLET safe to use in pregnant women?
A: THRIZE TABLET is not recommended for use in pregnant women. Consult your doctor for advice before taking this medicine if you are pregnant or planning to get pregnant.
Q: Is THRIZE TABLET safe to use in patients with heart disease?
A: THRIZE TABLET should be used with caution in patients with heart disease because it may increase the risk of increased heart rate. Consult your doctor for advice before taking this medicine.
Q: Can THRIZE TABLET be given to children?
A: There is no information regarding the use of THRIZE TABLET in children. Your child’s doctor will select a suitable alternative therapy for your child to manage the specific condition.
Q: What is THRIZE TABLET used for?
A: THRIZE TABLET is used in the management of pain and inflammation associated with osteoarthritis, rheumatoid arthritis, gout, joint issues related to inflammation, pain and swelling of joints, swelling associated with surgical wounds, pulmonary edema, ulcerative colitis, sports and accidental injuries, muscular cramps and spasms, tendinitis, bursitis, dental extraction, sinusitis, bronchitis, and rhinitis.
Q: How does THRIZE TABLET work?
A: THRIZE TABLET helps in managing pain and inflammation associated with various conditions where bromelain and trypsin are protease enzymes that decrease inflammation by inhibiting the substances that are responsible for it called proinflammatory prostaglandins. It also influences blood clotting by increasing the activity of a protein called fibrinogen. Rutoside is a flavonoid that works by enhancing the strength of blood vessels and decreasing their ability to break down.
Q: What are the side effects of THRIZE TABLET?
A: The most common side effects of taking THRIZE TABLET are nausea, diarrhea, stomach upset, tiredness, dry mouth, and skin rash. Consult your doctor if any of the side effects worsen.
Q: How should I take THRIZE TABLET?
A: Take THRIZE TABLET as advised by your physician. Swallow the medicine with enough water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of THRIZE TABLET for you depending on your age, body weight, and disease condition.
Q: Who should not take THRIZE TABLET?
A: THRIZE TABLET is not recommended for use in patients with hemophilia (a disorder in which blood doesn't clot normally), kidney disorders, patients undergoing haemodialysis, liver disorders, or if you are allergic to Bromelain, Rutoside and Trypsin. Consult your doctor before taking THRIZE TABLET.
Q: What precautions must be taken while using THRIZE TABLET?
A: Before taking THRIZE TABLET, inform your doctor if you have heart disease or any other bleeding disorder.
References
1. K.D. Tripathi. Drug Affecting Blood and Blood Formation, Autacoids and Related Drugs. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 616 & 204.
2. R.S. Satoskar, Nirmala N. Rege, S.D. Bhandarkar. Enzymes in Therapy. Pharmacology and Pharmacotherapeutics. Twenty Fourth Edition. 2015. Page – 1670, 1103.
3. Pavan R, Jain S, Shraddha, Kumar A. Properties and therapeutic applications of bromelain: a review. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. December 2012. [Accessed on 10th July 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529416/
4. Shah D, Mital K. The Role of Trypsin: Chymotrypsin in the Tissue Repair. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed.gov. January 2018. [Accessed on 10th July 2024] https://pubmed.ncbi.nlm.nih.gov/29209994/
5. Biobrick Pharma. Tryson-BR Tablets [Accessed on 10th July 2024] https://www.biobrickpharma.com/product/tryson-br-2/
6. DM Pharma. Kebon-3 Tablet. [Accessed on 10th July 2024] http://www.dmpharma.co.in/Trypsin_Bromelain_%20Rutoside_Tablets.html
7. BSA Pharma Inc. Inflabis BR Tablet. [Accessed on 10th July 2024] https://www.bsapharmainc.in/trypsinbromelainrutoside-tablets-inflabis-br/
8. Leogenic Health care. LeoTryps Tablet. [Accessed on 10th July 2024] https://www.leogenic.com/leotryps-trypsin-bromelain-rutoside-tablets/
9. Bionova. Reeca Forte Tablet. [Accessed on 10th July 2024] https://www.bionova.co.in/recca-forte.html
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Calcium
- Basic Arthritis Care
- Extended Arthritis Care
- Comprehensive Arthritis Care
- Frequent Pain Check Package
- Bone Strength Package
- Bone Profile – Advanced
- Autoimmune Arthritis Panel
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