NYG Pharmaceuticals Pvt Ltd

TENGREAT Tablet 10's

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Introduction About TENGREAT TABLET

TENGREAT TABLET is used as an adjunct to diet and exercise to control elevated blood sugar levels in adult patients with type II diabetes mellitus. It contains a medicine called Teneligliptin which lowers blood glucose levels by blocking the actions of an enzyme called dipeptidyl peptidase (DPP)-4 that regulates the secretion of insulin in the body.

During therapy with TENGREAT TABLET, your doctor might ask you to make certain lifestyle changes such as following a healthy diet, regular physical exercise, and quitting alcohol consumption.

Before taking TENGREAT TABLET, inform your doctor if you have any liver or heart problems. You must also inform your doctor if you have hormonal problems, stomach problems (surgery in the gut) or if you are malnourished, starved, on an irregular diet.

TENGREAT TABLET is not suitable for use in patients with type I diabetes mellitus. Consult your doctor before taking TENGREAT TABLET if you are pregnant or planning to become pregnant. 

One of the most common side effects of taking TENGREAT TABLET is hypoglycemia (blood sugar levels) which can be identified by symptoms such as increased hunger, sweating, shakiness, weakness, or an irregular heartbeat. To avoid this, your doctor will periodically monitor your blood sugar levels and adjust the dose of TENGREAT TABLET accordingly.

You can also carry a sugary snack (such as biscuits, glucose drinks or sweet candies) along with you as a precaution and have them immediately if you experience any signs of hypokalemia. However, consult your doctor if there is no improvement in your condition. Other common side effects of taking TENGREAT TABLET are headache, dizziness, and constipation.

Uses Of TENGREAT TABLET

  • It is used in adjunct to diet and exercise to manage type II diabetes mellitus in adults

How TENGREAT TABLET Works

TENGREAT TABLET effectively controls blood glucose levels in patients with type II diabetes mellitus. It contains teneligliptin which is a dipeptidyl peptidase (DPP)-4 inhibitor. It lowers blood glucose levels by blocking the actions of an enzyme called DPP-4 that regulates the secretion of insulin in the body. As a result, it improves insulin production and helps in the digestion of circulating blood glucose. It can also regulate blood sugar post meal by controlling glucagon secretion.

How to use TENGREAT TABLET

Take TENGREAT TABLET as advised by your physician.

Swallow the medicine with a glass of water. Do not crush or chew the medicine.

TENGREAT TABLET should be taken preferably after meals.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

Side Effects Of TENGREAT TABLET

Like all medications, this medicine may cause side effects, although they do not occur in everyone.

Common Side Effects of TENGREAT TABLET:

  • hypoglycemia (low blood sugar)
  • dizziness
  • headache
  • constipation, diarrhoea
  • fever

How To Manage Side Effects

Constipation

Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.

Diarrhea

Hydrate yourself by drinking plenty of fluids, such as water or fruit juices. Consuming ORS can also be beneficial. Do not self-manage diarrhea on your own. Consult your doctor if your diarrhea becomes uncontrollable.

Hypoglycemia

Have foods rich in sugars such as fruit juices, glucose drinks, candies, honey, or biscuits. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack, or a drink, and check the blood sugar again. consult your doctor if there is no improvement in your condition.

Warning & Precautions

Pregnancy

Monitoring required

TENGREAT TABLET should be used in pregnant women only if prescribed by the physician. Your doctor may prescribe TENGREAT TABLET for you after evaluating the risks and benefit ratio. Therefore, consult your doctor before taking it.

Breastfeeding

Contraindicated

Breast-feeding should be stopped during management with TENGREAT TABLET. However, consult your doctor before taking it.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel dizzy after taking TENGREAT TABLET.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking TENGREAT TABLET as it may increase the risks of side effects.

Liver

Use with Caution

TENGREAT TABLET should be used with caution in patients with severe liver diseases. Therefore, consult your doctor before taking it.

Allergy

Contraindicated

Do not take TENGREAT TABLET if you are allergic to Teneligliptin.

Heart Disease

Use with Caution

TENGREAT TABLET should be used with caution in patients with heart problems (like heart failure or slow heartbeat). Therefore, consult your doctor before taking it.

Use In Pediatrics

Consult your doctor

There is no proper information regarding the use of TENGREAT TABLET in children and in adolescents (below 18 years). Therefore, consult your doctor before taking it.

Use In Geriatrics

Use with Caution

TENGREAT TABLET should be used with caution in elderly patients. Therefore, consult your doctor before taking it. Proper dose adjustments and careful monitoring are required in such patients.

Others

TENGREAT TABLET is not recommended for use if you:

  • have severe ketosis (increased levels of ketone bodies in the blood)
  • have diabetic coma or precoma
  • have type I diabetes mellitus
  • have serious traumatic injury

Before taking TENGREAT TABLET, inform your doctor if you:

  • have pituitary insufficiency or adrenal insufficiency
  • are malnourished, starved, on an irregular diet, or feeling weak
  • perform extreme muscle exercises
  • have a history of abdominal operation or intestinal obstruction
  • have hypokalaemia (low blood potassium levels)

Interactions

A. Drug-Drug interactions:

Before taking TENGREAT TABLET, inform your doctor if you are taking any of the following medicines such as:

  • other medicines used to manage diabetes (such as glimepiride, exenatide, acarbose, metformin, pioglitazone, repaglinide, empagliflozin or insulin)
  • beta blockers (medicines used to manage high blood pressure) Ex. atenolol, propranolol
  • salicylic acid (a medicine used to manage skin problems like acne)
  • medicines used to manage depression (Ex. phenelzine, selegiline)
  • adrenaline (a medicine used to manage shock caused by allergic reactions or collapse)
  • thyroid hormones (used to manage thyroid deficiency) Ex. levothyroxine, liothyronine
  • medicines used to manage irregular heartbeats (Ex. quinidine, procainamide, amiodarone, sotalol, etc.)

Overdosage:

If you or anyone else accidentally took more TENGREAT TABLET, consult your doctor immediately or visit the nearby hospital.

Synopsis

Drug :   Teneligliptin
Pharmacological Category :   Dipeptidyl Peptidase-4 Inhibitors
Therapeutic Indication :   Type II Diabetes mellitus                     
Dosage Forms :   Tablet

More Information

Storage

  • Keep TENGREAT TABLET out of reach of children
  • Store TENGREAT TABLET at room temperature

FAQs About TENGREAT TABLET

Q: What is TENGREAT TABLET used for?

A: TENGREAT TABLET contains Teneligliptin which is used to manage type II diabetes (high blood sugar levels) in adults, that cannot be controlled by diet and exercise alone. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

Q: Is TENGREAT TABLET safe to use in pregnancy?

A: TENGREAT TABLET should be used in pregnant women only if prescribed by the physician. Your doctor may prescribe TENGREAT TABLET for you after evaluating the risks and benefit ratio. Therefore, consult your doctor before taking it.

Q: What precautions do I need to follow while taking TENGREAT TABLET?

A: Before taking TENGREAT TABLET, inform your doctor if you have any liver or heart problems. You must also inform your doctor if you have hormonal problems, stomach problems (surgery in the gut) or if you are malnourished. TENGREAT TABLET is not suitable for use in patients with type I diabetes mellitus. Consult your doctor before taking TENGREAT TABLET if you are pregnant or planning to become pregnant. During therapy with TENGREAT TABLET, follow the diet and lifestyle changes instructed by your doctor. Always carry a sugary snack (such as biscuits, glucose drinks or sweet candies) along with you as a precaution and have them immediately if you experience any signs of hypokalemia.

Q: Can I take medication for high blood pressure along with TENGREAT TABLET?

A: No. It is not advisable to take medicines to control blood pressure while taking TENGREAT TABLET without consulting your doctor. Therefore, consult your doctor before taking any antihypertensive such as beta blockers (Ex. atenolol, propranolol) along with TENGREAT TABLET as they have known interactions with TENGREAT TABLET.

Q: What should I do if I experience low blood sugar after taking TENGREAT TABLET?

A: Low blood sugar is a common side effect of taking TENGREAT TABLET. Try to have sugar rich food items such as fruit juice, glucose tablets or gel, soft drinks, honey, or sugary candy. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack, or drink, and check the blood sugar again. In case of persistent low blood sugar levels, consult your doctor immediately.

Q: Can TENGREAT TABLET cause dizziness?

A: Yes. Dizziness is a common side effect of using TENGREAT TABLET. In case you experience dizziness, lie down until it passes, then get up slowly and carefully. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, and alcohol. Do not drive or use machinery to avoid accidents. Consult your doctor if you experience dizziness continuousy for a long time after taking TENGREAT TABLET.

Q: Can TENGREAT TABLET be taken with insulin?

A: Co-administration of TENGREAT TABLET with insulin is considered risky as they are increased chances of hypoglycemia (decreased blood sugar levels). Consult your doctor before taking it.

Q: How to take TENGREAT TABLET?

A: You must take TENGREAT TABLET as advised by your physician. Try to take this medicine preferably after meals and swallow it with a glass of water. Do not crush or chew the medicine.

Q: How much TENGREAT TABLET should I take?

A: TENGREAT TABLET should be used only under medical supervision. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body condition and severity of the disease condition.

Q: Can TENGREAT TABLET cause constipation?

A: Yes. Constipation is a common side effect of using TENGREAT TABLET. Eat plenty of fiber rich foods such as fresh fruits, vegetables, cereals as well as drink plenty of water and exercise more regularly when taking this medicine. Contact your doctor if you experience constipation for a long time.

References

1. Joseph T. DiPiro, Robert L. Talbert, Gary C. Yee, Gary R. Matzke, Barbara G. Wells, L. Michael Posey. Diabetes Mellitus. Pharmacotherapy- A Pathophysiologic Approach. Eighth edition. Page- 1263, 1264.

2. Mitra, A., & Ray, S. Evaluation of the Safety and Efficacy of Teneligliptin at a Higher Dose in Indian Type 2 Diabetes Patients: A Retrospective Analysis. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. January 2020. [Accessed on 19th April 2022] click here

3. Torrent Pharmaceutical Ltd. Teneligliptin. [Revised in April 2021] [Accessed on 19th April 2022] click here

4. Mitsubishi Tanabe Pharma Factory Ltd. Teneligliptin. [Revised in April 2020] [Accessed on 19th April 2022] click here

Author Details

Written By Srilekha. R - B.Pharm
Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)
Last updated on 27 Nov 2024 | 04:16 PM(IST)
Lab updated