TELLZY CH 40/12.5mg Tablet 15's (N)

INTRODUCTION

TELLZY CH 40/12.5MG TABLET is a combination of Chlorthalidone and Telmisartan which belongs to the group of medicines called Diuretics and Angiotensin II receptor blockers, respectively. It is used to treat essential hypertension (high blood pressure) in affected individuals when monotherapy with chlorthalidone or telmisartan becomes inadequate to control the condition.

It is also used as an initial therapy in patients who are indicated for multiple drug therapy to control high blood pressure.

TELLZY CH 40/12.5MG TABLET is not recommended for use in patients allergic to chlorthalidone, telmisartan, and/or any sulphonamide derived medicines. It is also not recommended for use in patients suffering from anuria (failure of kidneys to produce urine) and severe liver impairment.

Before taking TELLZY CH 40/12.5MG TABLET, inform your doctor if you have liver problems (such as mild to moderate hepatic impairment), kidney problems (such as decreased renal function, severe renal impairment, nephrogenic diabetes insipidus), and/or heart problems (such as congestive heart failure).

TELLZY CH 40/12.5MG TABLET is not recommended for use in during pregnancy and in women planning for pregnancy. It is also not recommended for use in breastfeeding women since it passes through breastmilk.

TELLZY CH 40/12.5MG TABLET should be used with caution in children and adolescents (aged 6 to 18 years) and in elders (aged 65 years and above). Consult your doctor before taking the medicine.

The most common side-effects of taking TELLZY CH 40/12.5MG TABLET are back pain, sore throat, nausea, abdominal pain, indigestion, diarrhoea, and/or headache. Consult your doctor if any of these symptoms worsens.

USES OF TELLZY CH 40/12.5MG TABLET

• Treats hypertension to lower blood pressure

HOW TELLZY CH 40/12.5MG TABLET WORKS

TELLZY CH 40/12.5MG TABLET helps to lower blood pressure, where telmisartan works by blocking angiotensin (hormone responsible for regulating blood pressure and maintaining fluid balance in the body) which leads to relaxation of blood vessels and chlorthalidone works by removing extra water and certain electrolytes from the body which leads to relaxation of blood pressure and improved blood flow thus reducing high blood pressure in affected individuals.   

DIRECTIONS FOR USE

Take TELLZY CH 40/12.5MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF TELLZY CH 40/12.5MG TABLET

HOW TO MANAGE SIDE EFFECTS

Constipation

Try to eat high-fiber foods such as vegetables, cereals, fresh fruit, and drink plenty of water. Involve in regular exercise (going for a daily walk or run) and if this does not help, consult and inform your doctor for receiving alternate treatments for constipation.

Diarrhea

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.

Dizziness Or Drowsiness

Try to rest and get enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Limit consumption of alcohol, as it can aggravate dizziness. Consult and inform your doctor if the symptom worsens.

Headache

If TELLZY CH 40/12.5MG TABLET causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking TELLZY CH 40/12.5MG TABLET. If it lasts more than a week or severe, inform your doctor.

Nausea And Vomiting

Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods.

Skin Rash Or Itching

Try to pat or tap your skin instead of scratching it. Hold a damp towel to cool your skin. Wear loose clothing and avoid tight clothes, or clothes made from wool or synthetic fabrics. Avoid using perfumed soaps, deodorants or moisturizers and use a skin softener regularly.

WARNING & PRECAUTIONS

PREGNANCY

Monitoring required

TELLZY CH 40/12.5MG TABLET is generally not recommended for use during pregnancy unless it is considered clearly necessary. Treatment with TELLZY CH 40/12.5MG TABLET should be discontinued if you get pregnant. Consult your doctor before taking the medicine.

BREASTFEEDING

Contraindicated

TELLZY CH 40/12.5MG TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking the medicine.

KIDNEY

Use with Caution

TELLZY CH 40/12.5MG TABLET should be used with caution in patients undergoing haemodialysis and in patients with kidney problems such as decreased renal function, severe renal impairment, and nephrogenic diabetes insipidus. Consult your doctor before taking the medicine.

LIVER

Consult your doctor

TELLZY CH 40/12.5MG TABLET is not recommended for use in patients with severe liver impairment. It should be taken with caution in patients with liver disease such as mild to moderate hepatic impairment. Consult your doctor before the medicine.

ALLERGY

Contraindicated

Do not take TELLZY CH 40/12.5MG TABLET if you are allergic to chlorthalidone, telmisartan, any sulphonamide derived medicines, and/or any other ingredients of this medicine.

HEART DISEASE

Use with Caution

TELLZY CH 40/12.5MG TABLET should be used with caution in patients with heart diseases such as congestive heart failure. Consult your doctor before taking the medicine.

USE IN PEDIATRICS

Use with Caution

TELLZY CH 40/12.5MG TABLET should be used with caution in children and adolescents (aged 6 to 18 years). Consult your doctor before taking the medicine.

USE IN GERIATRICS

Use with Caution

TELLZY CH 40/12.5MG TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking the medicine.

INTERACTIONS

A. Drug-Drug interactions:

Before taking TELLZY CH 40/12.5MG TABLET, inform your doctor if you are taking any of the following medicine:

• aliskiren, ramipiril, guanethidine, methyldopa (medicines used to treat high blood pressure)
• digoxin (medicine used to treat heart failure)
• lithium (medicine used to treat mood disorders)
• non-steroidal anti-inflammatory agents (medicines used treat pain and inflammation) such as selective COX-2 inhibitors (Ex. celecoxib), indometacin
• anti-diabetics (medicines used to treat high blood sugar) Ex. metformin, glibenclamide, insulin
• anti-cholinergic agents (medicines used to treat nerve disorders) Ex. atropine, biperiden
• calcium salts (used to treat calcium deficiency)
• vitamin D (used to treat Vitamin D deficiency)
• cyclosporin (medicine used to prevent organ transplant rejection)
• other antihypertensive drugs (medicines used to treat hypertension) such as β-blockers (acebutolol, atenolol), vasodilators (Ex. benazepril, lisinopril), calcium antagonists (amlodipine, diltiazem), ACE inhibitors (benazepril, captopril)
• cholestyramine (used to lower high cholesterol level in blood)
• corticosteroids (medicines used to treat inflammation) Ex. prednisolone
• beta-2 agonists (used to treat asthma, bronchitis) Ex. salbutamol, terbutaline
• amphotericin (used to treat serious and life-threatening fungal infection)
• carbenoxolone (used to treat acid peptic disease)
• digitalis (used to treat heart conditions)
• allopurinol (used to lower uric acid level in blood)
• amantadine (used to treat Parkinson’s disease)
• diazoxide (used to manage symptoms of low blood sugar)
• cytotoxic agents (medicines used to prevent cancer cells from division and metastases) Ex. cyclophosphamide, methotrexate

B. Drug-Food interaction:

Avoid having very strict low-salt diet while taking TELLZY CH 40/12.5MG TABLET since it may cause undesirable effects.

Overdosage:

If you or anyone else accidentally take too much of TELLZY CH 40/12.5MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are low blood pressure, dizziness, fast heart rate, slow heart rate, nausea, sleeplessness, hypovolaemia (low blood volume), and electrolyte imbalances (associated with irregular heartbeat and muscle spasms).

SYNOPSIS

MORE INFORMATION

• Keep TELLZY CH 40/12.5MG TABLET out of reach of children
• Store the medicine at a cool, dry place away from the light

FAQs ABOUT TELLZY CH 40/12.5MG TABLET

Q: What is TELLZY CH 40/12.5MG TABLET used for?

A: TELLZY CH 40/12.5MG TABLET is used to treat essential hypertension (high blood pressure) in affected individuals when monotherapy with chlorthalidone or telmisartan becomes inadequate to control the condition.

Q: How TELLZY CH 40/12.5MG TABLET works?

A: TELLZY CH 40/12.5MG TABLET helps to lower blood pressure, where telmisartan works by blocking angiotensin (hormone responsible for regulating blood pressure and maintaining fluid balance in the body) which leads to relaxation of blood vessels and chlorthalidone works by removing extra water and certain electrolytes from the body which leads to relaxation of blood pressure and improved blood flow thus reducing high blood pressure in affected individuals.

Q: How TELLZY CH 40/12.5MG TABLET is taken?

A: Take TELLZY CH 40/12.5MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Q: What are the side effects of TELLZY CH 40/12.5MG TABLET?

A: The most common side-effects of taking TELLZY CH 40/12.5MG TABLET are back pain, sore throat, nausea, abdominal pain, indigestion, diarrhoea, and/or headache. Consult your doctor if any of these symptoms worsens.

Q: What happens if you take more TELLZY CH 40/12.5MG TABLET than the required dose?

A: If you or anyone else accidentally take too much of TELLZY CH 40/12.5MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are low blood pressure, dizziness, fast heart rate, slow heart rate, nausea, sleeplessness, hypovolaemia (low blood volume), and electrolyte imbalances (associated with irregular heartbeat and muscle spasms).

REFERENCES

1. KD Tripathi. Drugs Affecting Renin - Angiotensin System & Plasma Kinins and Antihypertensive Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 507,559.

2. Suresh V Sagarad, Sudha Biradar Kerure, Chaitanya Kumar S, and Ramakrishna MR. Sagarad  Kerure SB, Kumar S C, Mr R. The Antihypertensive Efficacy of Chlorthalidone and Telmisartan in Indian Hypertensive Patients who were Uncontrolled with Hydrochlorothiazide and Telmisartan Combination – A prospective and an open label study. NIH National Library of Medicine.  National center for biotechnology Information. February 2013. [Accessed on 10th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644445/

3. Mary M. Stephens, Beth A. Fox, and Lisa Maxwell. Therapeutic Options for the Treatment of Hypertension in Children and Adolescents. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. February 2012. [Accessed on 10th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296488/

4. Steris Healthcare PVT Ltd. Telmistrum CH 6.25.  [Accessed on 10th October 2022] https://www.sterisindia.com/latest-update/telmisartan-chlo/1402

5. Wonset Healthcare. TELVOK CH 20. [Accessed on 10th October 2022] https://wonset.co.in/products

6. Ciplamed. CRESAR CT Tablets. [Revised in February 2018] [Accessed on 10th October 2022] https://ciplamed.com/content/cresar-ct-tablets

7. Ipca Laboratories Ltd. CDT Tablet. [Accessed on 10th October 2022] https://www.ipca.com/pharmaceutical-formulations-manufacturers-india/

USEFUL DIAGNOSTIC TESTS

• Blood pressure test