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Tegrital CR 200mg Tablet 10'S

Epilepsy/Convulsion
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    Introduction About TEGRITAL CR 200MG TABLET

    TEGRITAL CR 200MG TABLET is a medication that may help to manage conditions related to neurological health. It is commonly used in people with specific seizure disorders.

    Carbamazepine controls seizure (fits) by decreasing the abnormal activity of the nerve cells in the brain. It also reduces pain by blocking the transmission of pain signals across the nervous system. It can stabilize your mood by reducing the activation of nerve cells at certain regions of the brain that causes abnormal mood changes. Your doctor would recommend you several blood tests to understand your existing condition.

    Inform your doctor if you have any liver or kidney diseases. TEGRITAL CR 200MG TABLET is not recommended for use in patients who have or ever had porphyria (a blood disorder), any heart or bone marrow problems. Avoid consumption of alcohol or grapefruit juice while taking TEGRITAL CR 200MG TABLET as it may lead to unwanted side effects.

    TEGRITAL CR 200MG TABLET should be used in pregnant and breastfeeding women only if it is considered necessary by the doctor. It is not recommended for use in children aged below 5 years. Common side effects of taking TEGRITAL CR 200MG TABLET are nausea, vomiting, increased bleeding tendency, headache, weight gain, dizziness, and blurred vision. Inform your doctor immediately if your mood becomes excessively depressed along with self-harming thoughts.

    Key Composition

    • Carbamazepine

    Uses Of TEGRITAL CR 200MG TABLET

    Used to manage,

    • Certain forms of epilepsy
    • Trigeminal neuralgia
    • Bipolar disorder if other medicines are not effective

    Benefits of TEGRITAL CR 200MG TABLET

    1. Extended-Release Formula for Consistent Control

    TEGRITAL CR 200MG is designed with a controlled-release mechanism, helping maintain a steady level of carbamazepine in the bloodstream over a longer duration. This helps reduce fluctuations in plasma levels, which can be particularly beneficial for individuals requiring continuous neurological support.

    2. Suitable for Long-Term Use (Under Medical Supervision)

    The tablet is often part of a long-term care plan. It is CR (controlled-release) design makes it a preferred choice for patients requiring chronic neurological management under ongoing healthcare supervision.

    3. Lower Pill Burden Compared to Immediate-Release Forms

    Because it releases medication slowly, TEGRITAL CR 200MG may require fewer daily doses than immediate-release versions, depending on your doctor’s instructions. This offers better convenience and may help reduce the chance of missed doses.

    4. Trusted Molecule with Clinical Backing

    Carbamazepine, the active ingredient in TEGRITAL CR 200MG, has been used in neurology for decades and is supported by multiple clinical guidelines and real-world evidence for its effectiveness in certain neurological conditions.

    4. Available in a Controlled-Strength Tablet

    Each tablet provides 200 mg of controlled-release carbamazepine, which helps healthcare providers tailor dosages more precisely for individual needs, especially when adjusting therapy gradually.

    How TEGRITAL CR 200MG TABLET Works

    TEGRITAL CR 200MG TABLET controls seizures by halting the abnormal build-up of electrical signals within the brain. It acts as a specific analgesic for trigeminal neuralgia, by blocking various pain reflexes caused by stimulation of nerves in the face. Also stabilizes mood by reducing the activation of nerve cells at certain regions of the brain that causes abnormal mood changes.

    How to use TEGRITAL CR 200MG TABLET

    1. How to take TEGRITAL CR 200MG TABLET for optimal effectiveness

    TEGRITAL CR 200MG is typically used under medical supervision for managing specific neurological conditions. To support consistent outcomes, it is essential to follow your healthcare provider’s instructions closely when taking this controlled-release medication.

    2. Recommended Dosage of TEGRITAL CR 200MG

    The dosage varies depending on:

    • The condition being managed (e.g., seizure type, nerve-related condition, mood imbalance)
    • Age, weight, and individual response.
    • Whether the patient is new to carbamazepine or transitioning from another medication
    • Most adults start at a low dose, which is gradually increased based on response and tolerance. Dosing is usually split into one or two times a day, depending on the prescribed regimen

    3. Adjusting the Dosage of TEGRITAL CR 200MG Based on Medical Advice

    Your doctor may:

    • Begin with a lower dose to assess how your body reacts.
    • Monitor blood levels of carbamazepine to adjust the dose for maximum safety and effectiveness
    • Modify the dose if other medications are added or removed

    4. How to administer TEGRITAL CR 200MG Tablets

    • Swallow the tablet whole with water. Do not chew, crush, or break the tablet
    • Take it after meals, unless advised otherwise. Food can help minimize gastrointestinal discomfort
    • Use at the same time daily for better consistency

    5. Important Considerations When Taking TEGRITAL CR 200MG

    • Avoid alcohol while taking this tablet, as it can interfere with brain activity and increase side effect risks.
    • Let your doctor know about all other medications, including herbal supplements and over-the-counter drugs
    • Regular blood tests may be recommended to monitor liver function, kidney function, and blood cell counts.

    6. Maximum Dosage and Safe Usage of TEGRITAL CR 200MG

    The maximum daily dose depends on the patient's age, condition, and clinical monitoring. Exceeding the prescribed dose can lead to serious health effects such as:

    • Confusion
    • Muscle twitching
    • Irregular heartbeat
    • Respiratory concerns

    7. Best Time of Day to take TEGRITAL CR 200MG

    • The tablet is commonly taken once or twice daily, depending on your doctor’s guidance.
    • For optimal adherence and steady drug levels, it is best to take it at the same time every day.
    • Evening doses may be preferred in some cases to reduce the impact of drowsiness

    What if I forgot to take TEGRITAL CR 200MG TABLET

    If you miss a dose:

    • Take it as soon as you remember within a few hours
    • If it is close to your next dose, skip the missed one, do not double up the dose
    • Contact your healthcare provider if you miss multiple doses in a row

    Side Effects Of TEGRITAL CR 200MG TABLET

    Common

    • reduced WBC count causing frequent infections
    • dizziness
    • tiredness
    • losing balance
    • nausea, or vomiting
    • abnormal bleeding and bruising
    • fluid retention and swelling
    • weight gain

    Serious side effects of TEGRITAL CR 200MG: When to Seek Help:

    • serious skin reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis (skin rash with widespread blistering and peeling of the skin, ulcerations in the mouth, throat, nose, genitals, and eyes, fever, flu-like symptoms, headache, and body ache) or lupus erythematosus (rash across the bridge of nose and cheeks with painful joints and muscles)
    • self-harming thoughts
    • fall due to dizziness, drowsiness, decreased blood pressure and confusion
    • signs of severe allergic reactions (such as skin rash, itching, swelling of face especially lips, throat, mouth, and eyes causing difficulty in breathing)
    • stomach pain

    Long-Term Side Effects of TEGRITAL CR 200MG: What to Watch For

    While not everyone experiences side effects, the following may appear with prolonged use:

    • Drowsiness or Fatigue: Extended use may lead to persistent tiredness or reduced alertness in some individuals, especially when the body is adjusting to stable levels.
    • Coordination and Balance Issues: Some users report dizziness, unsteadiness, or mild problems with motor skills. These effects may gradually diminish or require dose adjustments.
    • Mild Cognitive Impact: Difficulty concentrating or memory lapses can occur in rare cases, especially at higher doses
    • Gastrointestinal Sensitivity: Prolonged exposure may lead to nausea, constipation, or loss of appetite, particularly in sensitive individuals.

    How To Manage Side Effects

    Constipation

    • Drink plenty of water daily to soften stools and ease bowel movement
    • Add fibre-rich foods like fruits, vegetables, and whole grains to your meals
    • Stay physically active with daily walks or light exercise
    • Go to the bathroom when you feel the urge, do not delay
    • Establish a regular toilet routine, ideally after meals
    • Use over-the-counter stool softeners or laxatives only if recommended by a doctor
    • Limit caffeine and alcohol, as they can dehydrate the body
    • Monitor your symptoms and track bowel habits if constipation is frequent
    • Consult a doctor if constipation lasts more than 3 days or is recurring

    Dizziness Or Drowsiness

     

    • Hydrate by drinking water frequently
    • Eat small, regular meals to maintain blood sugar levels
    • Get up slowly from sitting or lying positions to avoid sudden drops in blood pressure
    • Avoid stress and overexertion, which can trigger lightheadedness
    • Take deep breaths if dizziness is related to anxiety or panic.

    Warning & Precautions

    Pregnancy

    Monitoring required

    TEGRITAL CR 200MG TABLET is not recommended in pregnant women unless considered necessary by the physician. It is also not recommended in women who are planning to become pregnant. Women of childbearing potential should use a suitable non-hormonal contraceptive method to avoid pregnancy during this treatment.

    Breastfeeding

    Use with Caution

    TEGRITAL CR 200MG TABLET should be used cautiously in breastfeeding women, as it may pass through breast milk and cause certain side effects in the breastfeeding infant.

    Driving and Using Machines

    Use with Caution

    Do not drive or operate any heavy tools or machines if you experience dizziness, drowsiness or blurred vision after taking TEGRITAL CR 200MG TABLET.

    Alcohol

    Consult your doctor

    Avoid consumption of alcohol after taking TEGRITAL CR 200MG TABLET.

    Kidney

    Use with Caution

    Caution is advised in patients having kidney diseases associated with low sodium level in the blood.  

    Liver

    Use with Caution

    TEGRITAL CR 200MG TABLET should be used cautiously in patients having liver diseases.

    Allergy

    Contraindicated

    Do not take TEGRITAL CR 200MG TABLET if you are allergic to Carbamazepine or similar medicines such as oxcarbazepine, phenytoin, primidone, phenobarbital, or antidepressants (such as amitriptyline or imipramine).

    Heart Disease

    Contraindicated

    TEGRITAL CR 200MG TABLET is not advised for use in patients having heart diseases.

    Use In Pediatrics

    Consult your doctor

    TEGRITAL CR 200MG TABLET is generally not recommended for use in children aged below 5 years. It should be used with caution in children and adolescents (aged between 5-15 years).

    Use In Geriatrics

    Use with Caution

    TEGRITAL CR 200MG TABLET should be used with caution in elderly patients.

    Other Warnings for TEGRITAL CR 200MG TABLET

    Before taking TEGRITAL CR 200MG TABLET, inform your doctor if you:

    • have absence seizure (seizure with brief sudden lapses of consciousness)
    • have any mental illness
    • have any eye conditions such as glaucoma (increased pressure in the eyes)
    • have any difficulties in retaining urine

    Who should not take [GBNKEYWORD

    TEGRITAL CR 200MG TABLET is not recommended for use if you:

    •  have or ever had any bone marrow disorders
    •  have porphyria

    Drug - Drug interaction

    Common Types of Drug-Drug Interactions

    1.Enzyme-inducing or inhibiting drugs: Some medicines (like carbamazepine) affect liver enzymes that process other drugs.

    Examples of concern:

    • Antidepressants (e.g., fluoxetine, sertraline)
    • Anticonvulsants (e.g., phenytoin, valproate)
    • Antifungals (e.g., ketoconazole, fluconazole)
    • Antibiotics (e.g., erythromycin)

    2.Blood-thinners (Anticoagulants): Interaction may affect clotting activity.

    Examples: Warfarin, Apixaban

    3.Hormonal medications: May reduce effectiveness of hormonal contraceptives.

    4.CNS-active drugs: Combining multiple brain-acting drugs may increase drowsiness or coordination problems

    Examples: Antipsychotics, Benzodiazepines, Opioids

    Drug - Food interaction

    Common Drug-Food Interactions to be aware of

    1. Grapefruit Juice:

    • May increase the levels of certain medications by blocking liver enzymes (CYP3A4).
    • Can lead to toxicity in some anticonvulsants, statins, or calcium channel blockers

    2. Dairy Products (Calcium): It can bind to certain antibiotics and reduce their effectiveness (e.g., tetracycline, ciprofloxacin)

    Synopsis

    Drug :   Carbamazepine
    Pharmacological Category :   Anti-convulsant drugs
    Therapeutic Indication :   Epilepsy, Bipolar disorder, Trigeminal neuralgia
    Dosage Forms :   Tablet, Syrup

    More Information

    Alternative Medications to TEGRITAL CR 200MG

    TEGRITAL CR 200MG contains carbamazepine, often prescribed for seizure control and neurological conditions. Depending on individual needs, doctors may consider other options that work differently or have varied dosing schedules. Some commonly used alternatives include:

    • Sodium Valproate: Known for broad-spectrum effectiveness in seizure management
    • Levetiracetam: Favored for fewer drug interactions and simpler dosing
    • Lamotrigine: Often prescribed when mood stabilization is also a consideration
    • Oxcarbazepine: A closely related drug with potentially fewer side effects
    • Topiramate: Sometimes chosen for specific seizure types or additional benefits like migraine control

    How TEGRITAL CR 200MG Tablet Compares with Other Seizure Medications

    Feature

    TEGRITAL CR (Carbamazepine)

    Levetiracetam

    Sodium Valproate

    Lamotrigine

    Mechanism of Action

    Blocks sodium channels to reduce nerve firing

    Modulates neurotransmitter release

    Increases GABA activity

    Stabilizes nerve membranes

    Common Use

    Partial seizures, trigeminal neuralgia

    Broad-spectrum seizures

    Generalized seizures

    Partial and generalized seizures

    Dosing Frequency

    Usually twice daily (controlled release)

    Twice daily or once daily

    Multiple times daily

    Once or twice daily

    Drug Interactions

    Moderate to high (enzyme inducer)

    Low

    Moderate

    Low to moderate

    Side Effects

    Dizziness, drowsiness, nausea

    Fatigue, irritability

    Weight gain, tremor

    Rash, dizziness

    Suitability for Pregnancy

    Requires caution and monitoring

    Generally preferred

    Usually avoided

    Sometimes preferred

    FAQs About TEGRITAL CR 200MG TABLET

    Q: How to use TEGRITAL CR 200MG TABLET?

    A: TEGRITAL CR 200MG TABLET can be taken during, between or after meals. Swallow the medicine with water. Do not crush or chew the medicine. Doctor will decide the suitable dose for you depending upon your age, body weight and disease condition.

    Q: What does TEGRITAL CR 200MG TABLET do to the brain?

    A: TEGRITAL CR 200MG TABLET manages seizures by stopping the abnormal build-up of electrical signals within the brain. It acts as a specific analgesic for trigeminal neuralgia, by blocking various pain reflexes caused by stimulation of nerves in the face. Acts as a mood stabilizer by reducing the activation of nerve cells at certain regions of the brain that causes abnormal mood changes.

    Q: What are the common side effects of taking TEGRITAL CR 200MG TABLET?

    A: The common side effects of taking TEGRITAL CR 200MG TABLET are nausea, vomiting, increased bleeding tendency, headache, weight gain, dizziness, and blurred vision.

    Q: Is TEGRITAL CR 200MG TABLET safe to use in children?

    A: TEGRITAL CR 200MG TABLET is not advised for use in children aged below 5 years. It should be used with caution in children and adolescents (aged between 5-15 years).

    Q: How long should I use TEGRITAL CR 200MG TABLET?

    A: Take TEGRITAL CR 200MG TABLET until your doctor suggests you discontinue the medicine. Do not stop taking TEGRITAL CR 200MG TABLET without consulting your doctor as it may make your symptoms to reappear.

    Q: Can TEGRITAL CR 200MG TABLET taken along with alcohol?

    A: No. Avoid consumption of alcohol while taking TEGRITAL CR 200MG TABLET as it might make you feel dizzier and may cause accidental injuries.

    Q: Can pregnant women take TEGRITAL CR 200MG TABLET?

    A: TEGRITAL CR 200MG TABLET is not recommended in pregnant women unless considered necessary by the physician. It is also not recommended in women who are planning to become pregnant. Women of childbearing potential should use a suitable non-hormonal contraceptive method to avoid pregnancy during this treatment.

    Q: Will taking a larger dose of TEGRITAL CR 200MG TABLET be more effective?

    A: No, Taking a higher dose of TEGRITAL CR 200MG TABLET may not be beneficial. Instead, it can cause serious side effects. If the prescribed dose is not effective for you, consult your doctor. Your doctor may prescribe a suitable higher dose or suggest an alternative therapy after evaluating your disease condition.

    Q: Can I take painkillers along with TEGRITAL CR 200MG TABLET?

    A: No. Avoid concomitant use of any pain killers like paracetamol, tramadol, dextropropoxyphene, methadone, and buprenorphine as it may lead to unwanted reactions.

    Q: What should I do if I forget to take a dose of TEGRITAL CR 200MG TABLET?

    A: If your forgot to take a dose of TEGRITAL CR 200MG TABLET, take it as soon as you remember. However, if it is time to take the next dose, skip the missed one and take the regular dose. Do not take a double dose to compensate the missed dose

    Q: Where to buy TEGRITAL CR 200MG TABLET Online?

    A: Order your TEGRITAL CR 200MG TABLET from our trusted online pharmacy Netmeds. Fast, secure, and convenient delivery options are available.

    References

    1. James O. McNamara. Pharmacotherapy of the Epilepsies. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 594-596.

    2. Jasdave S. Maan; Truc vi H. Duong, Abdolreza Saadabadi Carbamazepine. NIH National Library of Medicine, National center for biotechnology information. [Revised on 2nd May 2022] [Accessed on 9th July 2025]

    3. Philip J Wiffen, Sheena Derry, R Andrew Moore, and Henry J McQuay. Carbamazepine for acute and chronic pain in adults. NIH National Library of Medicine, National centre for biotechnology information. PubMed Central. September 2014. [Accessed on 9th July 2025]

    4. Novartis Pharmaceuticals UK Limited. Electronic Medicines Compendium (EMC). [Revised in November 2020] [Accessed on 9th July 2025]

    Useful Diagnostic Tests

    Author Details

    Written By Dr. Janet.C - Pharm.D
    Reviewed For Accuracy By Dr. Sankara Babu Gorle - MBBS, MD (Pharmacology)
    Last updated on 10 Jul 2025 | 09:59 AM(IST)
    Lab updated