TEGNECT M 20/500mg Tablet 10's
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Introduction About TEGNECT M 20/500MG TABLET
TEGNECT M 20/500MG TABLET is a medication used for managing type 2 diabetes. It helps regulate blood sugar levels effectively.
TEGNECT M 20/500MG TABLET controls blood sugar levels in type 2 diabetes patients, manages diabetes-related complications and improves insulin sensitivity.
Take TEGNECT M 20/500MG TABLET as prescribed by your doctor. Usually taken once daily with or without food.
Before taking TEGNECT M 20/500MG TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have low potassium levels in blood or are severely dehydrated due to excessive vomiting or diarrhea recently.
The most common side effects of taking TEGNECT M 20/500MG TABLET are nausea, stomach discomfort and low blood sugar (if combined with other diabetes medicines). Consult your doctor if any of the above side effects bother you.
Uses Of TEGNECT M 20/500MG TABLET
- Used to manage Type II diabetes
Benefits of TEGNECT M 20/500MG TABLET
1. Controls blood sugar levels in type 2 diabetes patients:
- TEGNECT M 20/500MG TABLET contains Teneligliptin and Metformin which work together to lower high blood glucose levels
- It enhances insulin secretion from the pancreas and reduces glucose production in the liver
- Helps maintain steady blood sugar levels throughout the day and after meals
2. Manages diabetes-related complications:
- By keeping blood sugar under control, TEGNECT M 20/500MG TABLET helps to manage long-term complications like:
- Nerve damage (neuropathy)
- Kidney problems (nephropathy)
- Eye diseases (retinopathy)
- Heart conditions (cardiovascular risks)
- Regular use as prescribed by a doctor can help improve overall health outcomes for diabetes patients
3. Improves insulin sensitivity:
- Metformin in TEGNECT M 20/500MG TABLET enhances the body's response to insulin, making it more effective
- Reduces insulin resistance, ensuring better glucose uptake by muscles and tissues
- Supports weight management in diabetes patients by managing excess fat accumulation
How TEGNECT M 20/500MG TABLET Works
TEGNECT M 20/500MG TABLET contains Metformin and Teneligliptin. Metformin works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body’s sensitivity to insulin. Teneligliptin is a dipeptidyl peptidase-4 inhibitor which works by increasing the release of insulin from pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and post-meal sugar levels. Together, they provide better control of blood sugar.
How to use TEGNECT M 20/500MG TABLET
How to take TEGNECT M 20/500MG TABLET correctly?
- Take TEGNECT M 20/500MG TABLET with a meal or immediately after eating
- Swallow whole, do not crush, chew, or break the tablet
- Take the exact dose prescribed by your doctor, do not increase or decrease the dose on your own
- Stick to a routine: Take it at the same time daily for consistent blood sugar control
- Follow a balanced diet, exercise regularly, and manage stress to improve diabetes control
TEGNECT M 20/500MG TABLET dosage instructions:
- The usual dose is one tablet once or twice daily with meals
- The dosage may vary depending on blood sugar levels, medical history, and other medications
- Do not self-adjust the dosage without consulting your doctor
What if I forgot to take TEGNECT M 20/500MG TABLET
- If you realize you missed a dose within a few hours, take it immediately with food
- If it is close to your next scheduled dose, skip the missed dose and continue with your regular routine
- Do not take a double dose to make up for the missed one, as this can increase the risk of low blood sugar (hypoglycemia)
Overdose
If you or anyone else accidentally took more of TEGNECT M 20/500MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are feeling cold, severe nausea or vomiting, stomach pain, unexplained weight loss, muscular cramps and fast breathing.
Side Effects Of TEGNECT M 20/500MG TABLET
Common side effects of TEGNECT M 20/500MG TABLET:
- nausea
- stomach discomfort
- low blood sugar (if combined with other diabetes medicines)
When to consult a doctor?
- serious allergic reaction (hives, swelling of the face, lips, tongue or throat causing difficulty in breathing or swallowing)
- severe skin rashes with redness and blistering of the skin
- signs of lactic acidosis (cold hands or feet, dizziness or light-headedness, slow or irregular heartbeat, weakness or tiredness, unusual muscle pain, trouble breathing, sleepiness or drowsiness, stomach pains, nausea or vomiting)
- signs of liver damage (tiredness, loss of appetite, weight loss, with or without yellowing of the skin or whites of the eyes)
How To Manage Side Effects
Nausea And Vomiting
- Always take TEGNECT M 20/500MG TABLET with a meal or immediately after eating
- Drink plenty of water throughout the day to manage dehydration
- Instead of large meals, try eating small, balanced meals throughout the day
- Ginger tea, ginger candies, or peppermint tea can help settle the stomach and reduce nausea
- Stay upright for at least 30 minutes after taking the medication to manage acid reflux and nausea
Stomach Discomfort
- Include fiber-rich foods like vegetables, whole grains, and fruits to aid digestion
- Avoid spicy, greasy, or processed foods, which can aggravate stomach discomfort
- Gentle physical activity like walking after meals can help improve digestion and reduce bloating
Warning & Precautions
Pregnancy
Consult your doctorHuman studies on Teneligliptin's safety during pregnancy are lacking. Animal studies have not shown harm to the fetus, but these results do not always predict human responses. Metformin’s long-term effects on offspring are still under investigation. Hence TEGNECT M 20/500MG TABLET should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus.
Breastfeeding
ContraindicatedAnimal studies indicate Teneligliptin may transfer into milk and cause caution. Metformin is present in human breast milk in low amounts. Hence TEGNECT M 20/500MG TABLET should be avoided by breastfeeding mothers.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel dizzy after taking TEGNECT M 20/500MG TABLET.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking TEGNECT M 20/500MG TABLET as it may increase the risk of unwanted side effects.
Kidney
ContraindicatedTEGNECT M 20/500MG TABLET is not recommended for use in patients with severely reduced kidney functions.
Liver
Consult your doctorTEGNECT M 20/500MG TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with gall stones.
Allergy
ContraindicatedDo not take TEGNECT M 20/500MG TABLET if you are allergic to Metformin or Teneligliptin or any other ingredients of this medicine.
Lungs
ContraindicatedTEGNECT M 20/500MG TABLET is not recommended for use in patients with severe infections of the lungs or respiratory tract.
Heart Disease
ContraindicatedTEGNECT M 20/500MG TABLET is not recommended for use in patients with severe heart problems (such as acute heart failure, recent heart attack, arrythmia, prolonged QT interval).
Use In Pediatrics
Consult your doctorThe safety and effectiveness of TEGNECT M 20/500MG TABLET have not been established in infants, children and adolescents (aged below 18 years).
Use In Geriatrics
Consult your doctorThe safety and effectiveness of TEGNECT M 20/500MG TABLET have not been established in elderly patients (aged 65 years or above).
Other Warnings for TEGNECT M 20/500MG TABLET
Before taking TEGNECT M 20/500MG TABLET, inform your doctor if you:
- have pituitary insufficiency or adrenal insufficiency
- are malnourished, starved, on an irregular diet, or feeling weak
- perform extreme muscle exercises
- have a history of abdominal operation or intestinal obstruction
- have hypokalaemia
- have type I diabetes mellitus
- have severe traumatic conditions
Who should not take [GBNKEYWORD
TEGNECT M 20/500MG TABLET is not recommended for use if you:
- have severe, uncontrollable diabetes
- have lactic acidosis or ketoacidosis
- are dehydrated (due to drinking less fluid or had severe vomiting or diarrhea during the recent days)
- have any severe systemic infection
- have shock or problems in blood circulation
Diet and Lifestyle Advice
Best foods to eat while TEGNECT M 20/500MG TABLET:
- Brown rice, quinoa, whole wheat bread, oats
- Lentils, chickpeas, kidney beans
- Spinach, kale, broccoli, carrots
- Apples, pears, oranges, berries
- Eggs, chicken, fish, tofu & paneer
- Broccoli, cauliflower, cabbage
Exercise tips to enhance the effectiveness of TEGNECT M 20/500MG TABLET:
- Cardiovascular (Aerobic) Exercises
- Strength Training – Builds Muscle & Burns Fat
- Flexibility & Balance Exercises – Manages Diabetes-Related Complications
- High-Intensity Interval Training (HIIT) – Quick & Effective
Foods & drinks to avoid while on TEGNECT M 20/500MG TABLET:
- Sugary foods & high-carb processed foods
- Fried & fatty foods
- Alcohol & caffeinated drinks
- High-sodium foods
- Dairy products with added sugar & artificial sweeteners
How to balance your diet to manage blood sugar spikes:
- Prioritize low-glycemic index (GI) foods
- Eat more protein with every meal
- Add healthy fats for better blood sugar control
- Control carbohydrate intake
- Stay hydrated & avoid sugary drinks
- Eat at regular intervals
- Plan a balanced plate (the diabetes plate method)
Drug - Drug interaction
1. Anti-diabetic medications (Risk of Hypoglycemia):
- Insulin, sulfonylureas (Glimepiride, Gliclazide, Glibenclamide)
- Precaution: Monitor blood sugar levels closely to prevent dizziness, sweating, and shakiness
2. Iodine contrast media (risk of lactic acidosis):
- Iodine-based contrast dyes (used for diagnostic imaging)
- Precaution: Stop TEGNECT M 20/500MG TABLET 48 hours before and after contrast imaging to prevent kidney-related complications
3. Bronchodilators:
- Salbutamol (Albuterol), terbutaline
- Precaution: Monitor blood sugar levels more frequently if using inhalers or nebulizers regularly
4. Corticosteroids:
- Prednisolone, Dexamethasone, Hydrocortisone, Steroid inhalers & injections
- Precaution: If steroids are necessary, adjust diabetes medication under medical supervision
5. Diuretics:
- Furosemide, Hydrochlorothiazide (HCTZ), Spironolactone
- Precaution: Stay hydrated and monitor kidney function regularly
6. NSAIDs:
- Ibuprofen, Naproxen, Diclofenac, Aspirin
- Precaution: Use NSAIDs cautiously and for short durations. Paracetamol is a safer alternative for pain relief
Drug - Food interaction
How does TEGNECT M 20/500MG TABLET compare to Metformin?
|
Feature |
TEGNECT M 20/500MG TABLET (Teneligliptin + Metformin) |
Metformin (Only) |
|
Drug Class |
DPP-4 Inhibitor + Biguanide |
Biguanide |
|
Composition |
Teneligliptin + Metformin |
Metformin |
|
Primary Action |
Increases insulin secretion + Reduces glucose production |
Reduces liver glucose production |
|
Effectiveness |
Stronger post-meal sugar control |
Better fasting sugar control |
|
Weight Impact |
Neutral (Does not cause weight gain) |
May help with weight loss |
|
Risk of Hypoglycemia |
Low risk |
Rare |
|
Common Side Effects |
Mild nausea, stomach discomfort |
GI issues (diarrhea, nausea, bloating) |
|
Best For |
Uncontrolled diabetes with high post-meal sugar |
First-line management for newly diagnosed diabetes |
|
Not Recommended For |
Patients with severe kidney/liver issues |
Patients with kidney disease (risk of lactic acidosis) |
|
Usage |
Prescribed when Metformin alone is insufficient |
First-choice medication for type 2 diabetes |
TEGNECT M 20/500MG TABLET vs. Insulin – Which works best for Type 2 Diabetes?
|
Feature |
TEGNECT M 20/500MG TABLET (Teneligliptin + Metformin) |
Insulin |
|
Drug Class |
DPP-4 Inhibitor + Biguanide |
Hormone replacement |
|
How It Works |
Increases insulin secretion & reduces glucose production |
Directly lowers blood sugar by increasing insulin levels |
|
Best For |
Mild to moderate Type 2 diabetes |
Advanced diabetes or uncontrolled cases |
|
Effectiveness |
Works well in early stages |
Most effective for high blood sugar levels |
|
Use in Post-Meal Sugar Control |
Very effective |
Works but needs dose adjustment |
|
Weight Impact |
Neutral (Does not cause weight gain) |
May cause weight gain |
|
Hypoglycemia Risk |
Low risk |
Higher risk |
|
Administration |
Oral tablet |
Injection |
|
Common Side Effects |
Mild nausea, stomach discomfort |
Hypoglycemia, weight gain, injection site reactions |
|
Cost & Accessibility |
More affordable and convenient |
Can be expensive and requires proper storage |
|
Prescribed When |
First-line management or when Metformin alone is insufficient |
When oral medications fail to control diabetes |
Onset of Action:
|
Factor |
Timeframe |
|
Initial Effect |
Within 1 to 2 hours after taking the tablet |
|
Peak Action |
Around 4 to 6 hours after administration |
|
Full Therapeutic Effect |
May take 1 to 2 weeks of regular use |
|
Long-Term Benefits |
Consistent blood sugar improvement over 4 to 8 weeks |
Synopsis
|
Drug |
: |
Metformin, Teneligliptin |
|
Pharmacological Category |
: |
Biguanides, DPP-4 Inhibitors |
|
Therapeutic Indication |
: |
Type II Diabetes mellitus |
|
Dosage Forms |
: |
Tablet |
More Information
Storage
- Keep TEGNECT M 20/500MG TABLET out of reach of children
- Store TEGNECT M 20/500MG TABLET at room temperature
FAQs About TEGNECT M 20/500MG TABLET
Q: What is TEGNECT M 20/500MG TABLET used for?
A: TEGNECT M 20/500MG TABLET is used as an adjunct to diet and exercise to control blood sugar levels in patients with type II diabetes mellitus.
Q: How does TEGNECT M 20/500MG TABLET work?
A: TEGNECT M 20/500MG TABLET is a combination medication containing Teneligliptin (DPP-4 inhibitor) and Metformin (Biguanide). It helps control blood sugar levels in Type 2 Diabetes Mellitus (T2DM) by targeting multiple pathways.
Q: Can TEGNECT M 20/500MG TABLET be used for type 1 diabetes?
A: No, TEGNECT M 20/500MG TABLET is not recommended for Type 1 Diabetes Mellitus (T1DM).
Q: What to do if I miss a dose of TEGNECT M 20/500MG TABLET?
A: Take it as soon as you remember, if it is not too close to the next scheduled dose. If it is almost time for the next dose, skip the missed dose and take the next one at the regular time. Do not double the dose to make up for the missed one, as it may lead to low blood sugar (hypoglycemia).
Q: Is TEGNECT M 20/500MG TABLET available over the counter?
A: No, TEGNECT M 20/500MG TABLET is a prescription medication and is not available over the counter.
Q: Can TEGNECT M 20/500MG TABLET cause weight gain or loss?
A: TEGNECT M 20/500MG TABLET is generally considered weight-neutral, meaning it is unlikely to cause significant weight gain or loss. However, individual responses may vary based on metabolism, diet, and lifestyle.
Q: Is TEGNECT M 20/500MG TABLET safe for long-term use?
A: Yes, TEGNECT M 20/500MG TABLET is generally considered safe for long-term use in Type 2 Diabetes Mellitus (T2DM) when taken under medical supervision. However, regular monitoring of kidney function, liver health, and blood sugar levels is essential to ensure safety.
Q: How and when to take TEGNECT M 20/500MG TABLET?
A: Take TEGNECT M 20/500MG TABLET preferably after meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Q: Can TEGNECT M 20/500MG TABLET be taken twice daily?
A: Yes, TEGNECT M 20/500MG TABLET can be taken twice daily, but only if prescribed by a doctor. The dosage depends on individual blood sugar levels, kidney function, and overall health condition.
Q: What are the most common side effects of taking TEGNECT M 20/500MG TABLET?
A: The most common side effects of taking TEGNECT M 20/500MG TABLET are nausea, stomach discomfort and low blood sugar (if combined with other diabetes medicines).
Q: Can I stop taking TEGNECT M 20/500MG TABLET without consulting your doctor?
A: No. You should not stop taking TEGNECT M 20/500MG TABLET without consulting your doctor because it may lead to reversal of symptoms.
Q: Will taking a higher dose of TEGNECT M 20/500MG TABLET be more effective?
A: No, taking a higher dose of TEGNECT M 20/500MG TABLET will not be effective it can lead to toxicity.
Q: Can I take medication for high blood pressure along with TEGNECT M 20/500MG TABLET?
A: Consult your doctor before taking any antihypertensive such as beta blockers (Ex. atenolol, propranolol) along with TEGNECT M 20/500MG TABLET as they have known interactions with this medicine.
Q: Can TEGNECT M 20/500MG TABLET Be taken on an empty stomach?
A: No, TEGNECT M 20/500MG TABLET should not be taken on an empty stomach. It is recommended to take it with or immediately after a meal to ensure proper absorption and to reduce the risk of side effects such as nausea, stomach upset, and acidity.
Q: Can TEGNECT M 20/500MG TABLET be used in pregnant women?
A: TEGNECT M 20/500MG TABLET should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Safe use of the medicine during pregnancy has not been established.
References
- KD. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 274 & 275.
- Linong Ji, Ling Li, Jianhua Ma, Xuefeng Li, Dongmei Li, Bangzhu Meng, Weiping Lu, Jiao Sun, Yanmei Liu, Gen Takayanagi and Yi Wang. Efficacy and safety of teneligliptin added to metformin in Chinese patients with type 2 diabetes mellitus inadequately controlled with metformin: A phase 3, randomized, double-blind, placebo-controlled study. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. January 2021. [Accessed on 20th May 2025]
- Rx Farma Limited. Electronic Medicines Compendium (EMC). [Revised in September 2019] [Accessed on 20th May 2025]
- Torrent Pharmaceutical Ltd. Teneligliptin. [Revised in April 2021] [Accessed on 20th May 2025]
- Centaur Pharmaceuticals Pvt Ltd. TEN20 – M. [Accessed on 20th May 2025]
- Johnlee Pharmaceuticals Pvt Ltd. TENALIP-M 1000. [Accessed on 20th May 2025]
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