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Introduction About TAZOTENE 0.10% GEL
TAZOTENE 0.10% GEL contains Tazarotene which belongs to the group of medicines called Retinoids. It is used to topically manage plaque psoriasis and acne vulgaris. Plaque psoriasis is a skin disease that causes dry, itchy, raised skin patches (plaques) covered with scales. Acne vulgaris is a common, usually self-limiting disease that causes inflammation of the sebaceous follicles of the face and upper body.
Before using TAZOTENE 0.10% GEL, inform your doctor if you have liver, kidney, or heart problems, eczema, or other skin problems. TAZOTENE 0.10% GEL is not recommended for use among pregnant women. TAZOTENE 0.10% GEL should be used with caution in breastfeeding women. Consult your doctor before using it.
It is not known if TAZOTENE 0.10% GEL is safe and effective for use in children and adolescents under 12 years of age. TAZOTENE 0.10% GEL for the management of acne has not been clinically evaluated in elderly patients (over 65 years).
The most common side effects of using TAZOTENE 0.10% GEL are itching, burning, redness, worsening of psoriasis, irritation, skin pain, peeling, and dry skin. Contact your doctor if any of the symptoms worsen.
Uses Of TAZOTENE 0.10% GEL
- Topically manage plaque psoriasis and acne vulgaris
How TAZOTENE 0.10% GEL Works
TAZOTENE 0.10% GEL is converted to its active form, tazarotenic acid, that binds to all three members of the retinoic acid receptor (RAR) family (RARa, RARβ, and RARγ) and may modify gene expression.
How to use TAZOTENE 0.10% GEL
Apply TAZOTENE 0.10% GEL as advised by your physician. It is for external use only. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of TAZOTENE 0.10% GEL
Common
- itching
- burning
- redness
- worsening of psoriasis
- irritation
- pain
- peeling
- dryness
Stop using TAZOTENE 0.10% GEL and contact your doctor immediately if you experience any of the following side effects:
- skin irritation and allergic reactions (hives, itching, burning, redness, blistering, or peeling of your skin)
- sunlight sensitivity and risk of sunburn
Warning & Precautions
Pregnancy
ContraindicatedTAZOTENE 0.10% GEL is not recommended for use in pregnancy as it may cause birth defects. Consult your doctor before using it.
Breastfeeding
Use with CautionTAZOTENE 0.10% GEL should be used with caution in breastfeeding women as it is not known if it passes into breast milk. Consult your doctor before using it.
Allergy
ContraindicatedDo not use TAZOTENE 0.10% GEL if you are allergic to Tazarotene.
Use In Pediatrics
Consult your doctorIt is not known if TAZOTENE 0.10% GEL is safe and effective in children and adolescents (under 12 years of age). Consult your doctor before using it.
Use In Geriatrics
Consult your doctorTAZOTENE 0.10% GEL for the management of acne has not been clinically evaluated in elderly patients (over 65 years). Consult your doctor before using it.
Others
Before using TAZOTENE 0.10% GEL, inform your doctor if you:
- eczema or other skin problems
Interactions
A. Drug-Drug interactions:
Before using TAZOTENE 0.10% GEL, inform your doctor if you are using, have used, or might use any other medicine, including prescription, non-prescription or herbal medicine.
Overdosage:
If you or anyone else accidentally use too much of TAZOTENE 0.10% GEL, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include marked redness, peeling, or discomfort.
Synopsis
| Drug | : | Tazarotene |
| Pharmacological Category | : | Acetylenic retinoid |
| Therapeutic Indication | : | Plaque psoriasis, acne vulgaris |
| Dosage Forms | : | Cream, Gel |
More Information
- Keep TAZOTENE 0.10% GEL out of reach of children
- Store between 20-25°C
FAQs About TAZOTENE 0.10% GEL
Q: Is TAZOTENE 0.10% GEL safe to use during pregnancy?
A: TAZOTENE 0.10% GEL may cause birth defects if used in pregnancy. Women must not be pregnant when they start using or during management with this medicine. For women who get pregnant, your doctor will order a pregnancy test within 2 weeks before you begin management with TAZOTENE 0.10% GEL to be sure that you are not pregnant.
Get safety advice from your doctor for using TAZOTENE 0.10% GEL during a normal menstrual period. Discuss with your doctor about birth control options that may be used during the management. Stop using it and tell your doctor immediately if you become pregnant while using this medicine.
Q: What if TAZOTENE 0.10% GEL accidentally gets into my eye?
A: Avoid getting TAZOTENE 0.10% GEL in your eyes or eyelids. If it gets in or near your eyes, rinse them thoroughly with water. Call your doctor if you have persistent eye irritation. Wash your hands after applying TAZOTENE 0.10% GEL.
Q: What should I avoid while using TAZOTENE 0.10% GEL?
A: While using TAZOTENE 0.10% GEL, avoid exposure to sunlight, including sunlamps. Use sunscreen and cover your skin if you have to be in the sun. Avoid using cosmetics or topical medicines that may make your skin more sensitive to the sun or dry. Avoid using it on unaffected skin or skin with eczema, as it may cause severe irritation.
Q: What if I accidentally swallow TAZOTENE 0.10% GEL?
A: Avoid getting TAZOTENE 0.10% GEL in your mouth. If you or anyone else swallows it, call your doctor or go to the nearest hospital immediately.
Q: Can TAZOTENE 0.10% GEL cause itching?
A: Yes. TAZOTENE 0.10% GEL may cause itching. In such a case, pat your skin instead of scratching it and hold something cool, like a damp towel, on it. Wear loose cotton clothes. Consult your doctor if you have persistent itching.
References
1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Acne vulgaris. Pharmacotherapy Handbook. Ninth edition. Page- 135.
2. Allergan USA, Inc. U.S. Food & Drug Administration. [Revised in April 2018] [Accessed 26th May 2021] https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/020600s010lbl.pdf
3. Almirall LLC. Tazarotene. [Revised in August 2019] [Accessed 26th May 2021] https://www.tazorachcp.com/static/tazorac-cream-pi-54115b39c03f775e241400f432307541.pdf
4. Almirall LLC. Tazarotene. [Revised in August 2019] [Accessed 26th May 2021] https://www.tazorachcp.com/static/tazorac-gel-pi-02a09c0c385acf94ad9c3227b66febfd.pdf
5. Drugbank. Tazarotene. [Accessed 26th May 2021] https://go.drugbank.com/drugs/DB00799
6. Mayo clinic. Psoriasis. [Accessed 26th May 2021] https://www.mayoclinic.org/diseases-conditions/psoriasis/symptoms-causes/syc-20355840
7. Itchy skin. NHS UK. [Revised in July 2020] [Accessed 26th May 2021] https://www.nhs.uk/conditions/itchy-skin/
Useful Diagnostic Tests
- Skin biopsy

