New Revised MRP, 100% GST benefit passed Tavin L Tablet 30'S
Netmeds First Membership
Quick Links
Introduction About TAVIN L
TAVIN L is a combination of Lamivudine and Tenofovir which belongs to the group of medicines called Antiviral agents. It is used to manage HIV (Human Immunodeficiency virus) infection in adults and children aged above 18 years. It is also used in combination with other antiretroviral agents.
HIV is the virus that causes Acquired Immune Deficiency Syndrome (AIDS) and symptoms include weight loss, fever or night sweats, fatigue and recurrent infections. Prior to the management, your doctor may order several blood tests to assess your kidney and liver function. Before taking this medicine inform your doctor if you have kidney disease, liver disease such as hepatitis B and hepatitis C infection or hepatic dysfunction or lung disease such as tuberculosis. TAVIN L is generally not recommended for use in pregnant women unless considered clearly necessary.
TAVIN L is generally not recommended for use in breastfeeding women as it may pass through the breast milk. TAVIN L is not recommended for use in children and adolescents under 18 years of age. TAVIN L should be used with caution in elderly patients aged 65 years or above. Contact your doctor before taking. The most common side effects of taking TAVIN L are nausea, vomiting, headache, diarrhea, stomach pain, bloating, flatulence, fever, tiredness, rash, pain, depression and hair loss. Contact your doctor if any of the side effects worsen.
Uses Of TAVIN L
- Used to manage HIV infection
How TAVIN L Works
TAVIN L helps to manage HIV infection, where Lamivudine and Tenofovir inhibit the activity of reverse transcriptase enzyme (used by HIV for making copies of it) after incorporation into viral DNA, causes DNA chain termination and works against the virus.
How to use TAVIN L
Take this medicine as advised by your physician. Swallow this medicine as whole with a glass of water and do not crush or chew the medicine. Your doctor will decide the right dose depends on the age, body weight and disease condition.
Side Effects Of TAVIN L
Common
- nausea
- vomiting
- headache
- diarrhea
- stomach pain
- bloating
- flatulence
- tiredness or lack of energy
- dizziness
- fever, feeling of being unwell
- muscle pain and discomfort
- joint pain
- difficulty in sleeping (insomnia)
- cough, runny nose
- rash
- hair loss
- decreases in phosphate in the blood
- liver problems
Uncommon
- pancreatitis (inflammation of the pancreas)
- damage to kidney tubule cells
- thrombocytopenia (decrease in platelet count)
- anaemia (low red blood cell count)
- neutropenia (decrease in white blood cell count)
- elevated liver enzymes
- decreases in potassium in the blood
- increase in creatinine in the blood
- breakdown of muscle, softening of the bones or bone pain, fractures
- muscle pain, muscle weakness
Rare
- increase in an enzyme (amylase)
- inflammation of the kidney, increased urine frequency, and feeling thirsty
- kidney problems
- softening of the bones
- lactic acidosis
- serious allergic reaction causing swelling of the face, lips, tongue or throat results in difficulty in swallowing or breathing
Stop taking TAVIN L and contact your doctor immediately if you experience any of the following side effects:
- lactic acidosis (symptoms include feel very weak or tired, unusual muscle pain, breathing difficulty, stomach pain with nausea and vomiting, feel cold, especially in your arms and legs, dizziness or lightheadedness, rapid heart rate)
- liver disease (hepatomegaly or steatosis) such as yellowing of skin or the white part of your eyes (jaundice), dark or tea coloured urine, light-coloured stools, loss of appetite, nausea or vomiting, stomach pain
- pancreatitis (symptoms include severe upper stomach-area pain, with or without nausea and vomiting)
How To Manage Side Effects
Bloating
Eat smaller and frequent meals. Eat and exercise regularly. If the symptom does not improve, contact your doctor.
Diarrhea
Drink lots of fluids, such as water or fruit juices to keep you hydrated. Do not take any medicine on your own for managing diarrhea. Contact your doctor if the symptom did not improve.
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling dizzy. Do not consume alcohol, as it can aggravate your dizziness. Contact your doctor if the symptom did not improve.
Headache
Rest and relax. Drink plenty of fluids such as water or electrolytes and apply a pain-relieving balm on the head if necessary. Contact your doctor if the symptom did not improve.
Nausea And Vomiting
Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods.
Stomach Discomfort
Try to rest and relax. Eat small meals but take frequently. Keep a heat pad on your stomach. If the symptom does not improve, contact your doctor.
Warning & Precautions
Pregnancy
ContraindicatedTAVIN L is generally not recommended for use in pregnant women unless considered clearly necessary. Contact your doctor before taking it.
Breastfeeding
ContraindicatedTAVIN L is not recommended for use in breast-feeding women as it may pass through the breast milk. Contact your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate any machines, if you feel dizziness, after taking TAVIN L.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking this medicine, it can aggravate your existing condition.
Kidney
Use with CautionTAVIN L should be used with caution in patients with kidney disease such as acute renal failure and end-stage renal disease. Contact your doctor before taking.
Liver
Use with CautionTAVIN L should be used with caution in patients with liver disease such as hepatitis B and hepatitis C infection or hepatic dysfunction. Consult your doctor before taking.
Allergy
Use with CautionDo not take TAVIN L if you are allergic to Lamivudine, Tenofovir or to other ingredients of this medicine.
Lungs
Use with CautionTAVIN L should be used with caution in patients with lung disease such as tuberculosis. Contact your doctor before taking.
Use In Pediatrics
ContraindicatedTAVIN L is not recommended for use in children and adolescents under 18 years of age. Contact your doctor before taking.
Use In Geriatrics
Use with CautionTAVIN L should be used with caution in elderly patients aged 65 years or above. Contact your doctor before taking.
Others
Before taking TAVIN L, inform your doctor if you:
- have pancreatitis
- have bone problems such as osteonecrosis, osteoporosis or low bone mineral density (BMD) or history of bone fractures
- have AIDS or others infection
- have autoimmune disorders (Ex. Graves’disease, polymyositis, and Guillain-Barré syndrome)
- have immune reconstitution syndrome
- have fanconi syndrome
- have opportunistic infections
- have symptoms of infection include muscle weakness, weakness beginning in the hands and feet and moving up towards the trunk of the body, palpitations, tremor or hyperactivity
- are overweight
Interactions
A. Drug-Drug interactions:
Before taking TAVIN L inform your doctor if you are taking any of the following medicine:
- medicines used to manage HIV infection or hepatitis B infection (Ex. disoproxil, tenofovir alafenamide, didanosine, emtricitabine, lamivudine, adefovir dipivoxil, atazanavir lopinavir/ritonavir, darunavir)
- medicines that may damage your kidneys (Ex. gentamycin, pentamidine or vancomycin (for bacterial infection)
- amphotericin B (used for fungal infection)
- foscarnet, ganciclovir, or cidofovir (used for viral infection)
- interleukin-2 (used to manage cancer)
- tacrolimus (medicines used to suppress immune system)
- non-steroidal anti-inflammatory medicines (used to relieve bone or muscle pains) (Ex. diclofenac, ibuprofen)
- co-trimoxazole (used to manage bacterial infection)
- cladribine (medicine used for hairy cell leukaemia)
- ledipasvir, sofosbuvir, velpatasvir, voxilaprevir, ribavirin (medicines used to manage hepatitis C infection)
- trimethoprim (used for urinary tract infections)
- sorbitol (medicines used to manage constipation)
Overdosage:
If you or anyone else accidentally took too much of this medicine, consult your doctor immediately. Symptoms of overdose include lactic acidosis (excess lactic acid in the blood), abdominal pain caused by inflammation of the pancreas, damage to kidney tubule cells and worsening of liver disease.
Synopsis
| Drug | : | Lamivudine, Tenofovir |
| Pharmacological Category | : | Antiviral agents |
| Therapeutic Indication | : | HIV infection |
| Dosage Forms | : | Tablet |
More Information
- Keep out of reach of children
- Store below 25°C
FAQs About TAVIN L
Q: How TAVIN L works?
A: TAVIN L helps to manage HIV infection, where Lamivudine and Tenofovir inhibit the activity of reverse transcriptase enzyme (used by HIV for making copies of it) after incorporation into viral DNA, causes DNA chain termination and works against the virus.
Q: What are the side effects of taking TAVIN L?
A: The most common side effects of taking TAVIN L are nausea, vomiting, headache, diarrhea, stomach pain, bloating, flatulence, fever, tiredness, rash, pain, depression and hair loss. Contact your doctor if any of the side effects worsen.
Q: Does TAVIN L cause weight gain?
A: Yes. TAVIN L may cause weight gain. Contact your doctor if you experience any unusual symptoms like changes in body fat such as increased amount of fat in the upper back and neck (buffalo hump), breast, and around the main part of the body (trunk).
Q: Can I use TAVIN L in pregnancy?
A: No. TAVIN L is generally not recommended for use in pregnant women unless considered clearly necessary. Contact your doctor before taking it.
References
1. Cipla (EU) Limited. Electronic Medicines Compendium (EMC). [Revised on November 2021] [Accessed on 21st May 2022] https://www.medicines.org.uk/emc/files/pil.10500.pdf
2. Celltrion Pharm, Inc. U.S. Food & Drug Administration. [Revised on November 2018] [Accessed on 21st May 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/211284s000lbl.pdf
3. Mylan Pharmaceuticals Inc. U.S. Food & Drug Administration. [Revised on February 2018] [Accessed on 21st May 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/022141s000lbl.pdf
Useful Diagnostic Tests
- Kidney function test
- Liver function test
Author Details
