Emcure Pharmaceuticals Ltd

Sylate 250mg Injection 1'S

MRP ₹52.31 (Inclusive of all taxes)
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Introduction About SYLATE 250MG INJECTION

SYLATE 250MG INJECTION contains Ethamsylate, which belongs to the group of medicines called Antihemorrhagic drugs. It is used to manage bleeding from the blood vessels and to manage bleeding before or after an operation.

Ethamsylate exerts hemostatic action by improving platelet adhesiveness and restoring capillary (blood vessels) resistance. It decreases bleeding time and increases platelet clumping which reduces capillary bleeding and improves capillary wall stability. Before the management, your doctor might want to do certain blood tests to understand your existing condition.

SYLATE 250MG INJECTION is not recommended for use if you have porphyria (defect in the synthesis of haemoglobin) or bronchial asthma. Before receiving SYLATE 250MG INJECTION inform your doctor if you have hypotension or unstable blood pressure. SYLATE 250MG INJECTION should be used with caution in pregnant women. It is not recommended for use in breastfeeding women. Consult your doctor if you experience any unusual effects while receiving SYLATE 250MG INJECTION.

Uses Of SYLATE 250MG INJECTION

  • Prevents and manages bleeding from the blood vessels
  • Prevent bleeding before or after an operation

How SYLATE 250MG INJECTION Works

SYLATE 250MG INJECTION exerts hemostatic action by improving platelet adhesiveness and restoring capillary (blood vessels) resistance. It decreases bleeding time and increases platelet clumping which reduces capillary bleeding and improves capillary wall stability. It inhibits PGI-2 synthesis and corrects abnormal platelet function.

How to use SYLATE 250MG INJECTION

SYLATE 250MG INJECTION will be given to you only by a doctor or a nurse into the muscles (intramuscularly) or the veins (intravenously). Your doctor will decide the right dose and duration depending on your age, body weight and disease condition.

Warning & Precautions

Pregnancy

SYLATE 250MG INJECTION should be used with caution in pregnant women or if you are planning to have a baby. Consult your doctor before receiving it.

Breastfeeding

SYLATE 250MG INJECTION is not recommended for use in breastfeeding women as it is unknown if the medicine is excreted in breast milk. Consult your doctor before receiving it.

Allergy

Do not receive SYLATE 250MG INJECTION if you are allergic to Ethamsylate or any other ingredients of this medicine.

Lungs

SYLATE 250MG INJECTION is not recommended for use in patients with bronchial asthma. Consult your doctor before receiving SYLATE 250MG INJECTION.

Heart Disease

SYLATE 250MG INJECTION should be used with caution in patients with hypotension and unstable blood pressure. Consult your doctor before receiving SYLATE 250MG INJECTION.

Others

SYLATE 250MG INJECTION is not recommended for use if you:

  • have porphyria (defect in the synthesis of haemoglobin)

Interactions

A. Drug-Drug interactions:

Before receiving SYLATE 250MG INJECTION, inform your doctor if you are taking any prescription, nonprescription or herbal medicines.

Overdosage:

SYLATE 250MG INJECTION will be administered to you only by a doctor or a nurse in a hospital, so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.

Synopsis

Drug :   Ethamsylate
Pharmacological Category :   Antihemorrhagic agent
Therapeutic Indication :   Bleeding from blood vessels, perioperative bleeding
Dosage Forms :   Tablet, Injection

More Information

  • Keep SYLATE 250MG INJECTION out of reach from children
  • Store below 30°C

FAQs About SYLATE 250MG INJECTION

What is SYLATE 250MG INJECTION used for?

SYLATE 250MG INJECTION contains Ethamsylate which belongs to the group of medicines called Antihemorrhagic drugs. It is used to manage bleeding from the blood vessels and to manage bleeding before or after an operation.

Can SYLATE 250MG INJECTION be received by pregnant or breastfeeding women?

SYLATE 250MG INJECTION is not recommended for use in breastfeeding women. And it should be used with caution in pregnant women or women planning to have a baby. Consult your doctor before receiving SYLATE 250MG INJECTION.

How SYLATE 250MG INJECTION works?

It exerts hemostatic action by improving platelet adhesiveness and restoring capillary (blood vessels) resistance. It decreases bleeding time and increases platelet clumping which reduces capillary bleeding and improves capillary wall stability. It inhibits PGI-2 synthesis and corrects abnormal platelet function.

When is SYLATE 250MG INJECTION contraindicated?

SYLATE 250MG INJECTION is not recommended for use in patients with hypersensitivity to this medicine, porphyria (defect in the synthesis of haemoglobin) and bronchial asthma. Consult your doctor for more information.

Can SYLATE 250MG INJECTION be used in patients with heart problems?

SYLATE 250MG INJECTION should be used with caution in patients with hypotension and unstable blood pressure. Consult your doctor for more information on duration and dosage before receiving SYLATE 250MG INJECTION.

References

1. KD Tripathi. Drugs Affecting Coagulation, Bleeding and Thrombosis. Essentials of medical pharmacology. Eighth Edition. 2019. Page –662.

2. Ricardo P Garay, Carlo Chiavaroli, Patrick Hannaert. Article name. Therapeutic efficacy and mechanism of action of ethamsylate, a long-standing hemostatic agent. National library of medicine, National center for biotechnology information. Pubmed.gov 2006 [Accessed on 9th July 2022] https://pubmed.ncbi.nlm.nih.gov/16772766/

3. M.E.IMorgan I.W.TBenson JBenson R.W.I Cooke. Ethamsylate reduces the incidence of periventricular haemorrhage in very low birthweight babies. The lancet 1981. [Accessed on 9th July 2022] https://www.sciencedirect.com/science/article/abs/pii/S014067368191103X

4. Ethamsylate. CIMS. [Accessed on 9th July 2022] https://www.mims.com/india/drug/info/etamsylate?type=full&mtype=generic

Useful Diagnostic Tests

  • Blood tests

Author Details

Written By Dr. Dhivakaran R - BDS
Reviewed For Accuracy By Dr. Venkatesh Poludasu - MBBS
Last updated on 09 Nov 2022 | 04:57 PM(IST)
Lab updated