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Introduction About SUSTEN SR 200MG TABLET
Susten SR 200mg Tablet is a progesterone-based medicine commonly recommended for women who need support in maintaining hormonal balance, especially in conditions linked to low progesterone levels. It is often considered in cases such as irregular menstrual cycles, hormonal imbalance, or as part of fertility-related care where progesterone plays a key role. Progesterone is an essential hormone that helps regulate the menstrual cycle and supports the health of the uterine lining. The sustained-release (SR) formulation ensures gradual release of the hormone, helping maintain stable levels throughout the day.
This medicine is typically suitable for women experiencing symptoms of progesterone deficiency, including irregular or missed periods, or those undergoing medically guided reproductive care. It works by supporting the uterine lining and balancing the effects of estrogen, thereby improving cycle regularity and overall reproductive health. Clinical use of progesterone in gynaecological practice is well established, particularly in managing luteal phase support and hormonal imbalance under medical supervision.
Susten SR 200mg Tablet is usually taken after food, swallowed whole with water, and at a fixed time each day to maintain consistent hormone levels. It is important to follow the exact dose and duration prescribed by the doctor and avoid skipping doses or stopping the medicine abruptly. Women should inform their doctor about any history of liver disorders, blood clots, breast conditions, or unexplained vaginal bleeding before starting this medicine. Caution is also advised when using it alongside other hormonal therapies or medicines that may affect liver enzymes.
During pregnancy, this medicine may be used if prescribed, depending on individual requirements, while breastfeeding use should be guided by a healthcare professional as small amounts may pass into breast milk. Common side effects include dizziness, headache, nausea, breast tenderness, abdominal discomfort, and mild mood changes. These are generally temporary, but any persistent or severe symptoms should be reported. Regular follow-up with a doctor helps ensure safe and appropriate use tailored to individual health needs.
Uses Of SUSTEN SR 200MG TABLET
- Supports hormonal balance in women with progesterone deficiency
- Helps regulate menstrual cycle irregularities
- Provides support in fertility-related hormonal management
- Aids in maintaining uterine lining health
Benefits of SUSTEN SR 200MG TABLET
Susten SR 200mg Tablet for Hormonal Balance in Women with Progesterone Deficiency
Susten SR 200mg Tablet supports women who have low levels of progesterone, a key hormone involved in maintaining hormonal stability. It helps restore balance between estrogen and progesterone, which is important for overall reproductive health. By providing sustained-release progesterone, it ensures consistent hormone levels throughout the day. This support may help reduce symptoms linked to hormonal imbalance such as irregular cycles or discomfort. It is used under medical guidance based on individual hormonal needs.
Susten SR 200mg Tablet for Menstrual Cycle Irregularities
Susten SR 200mg Tablet helps regulate menstrual cycles in women experiencing irregular or delayed periods due to hormonal imbalance. Progesterone plays an essential role in controlling the timing and pattern of the menstrual cycle. By supporting the natural cycle, this medicine helps bring better predictability and rhythm to periods. It may also assist in reducing associated symptoms like mood changes or discomfort. Regular use as prescribed supports improved cycle consistency over time.
Susten SR 200mg Tablet for Fertility-Related Hormonal Management
Susten SR 200mg Tablet is often considered in fertility-related care where progesterone support is required. It helps prepare the uterus by supporting a suitable environment for implantation. Maintaining adequate progesterone levels is important in early stages of pregnancy-related planning. The sustained-release formulation ensures steady hormone support throughout the day. It is used as part of a doctor-guided plan tailored to individual reproductive health needs.
Susten SR 200mg Tablet for Maintaining Uterine Lining Health
Susten SR 200mg Tablet supports the development and maintenance of the uterine lining (endometrium), which is essential for normal reproductive function. Progesterone helps transform and stabilize the lining, making it suitable for natural cycle processes. Proper maintenance of this lining is important for menstrual health and hormonal balance. The medicine provides consistent support through its sustained-release action. It is used under medical supervision for optimal benefits.Top of Form
How SUSTEN SR 200MG TABLET Works
Mechanism of Action of Susten SR 200mg Tablet
Susten SR 200mg Tablet contains progesterone, a natural hormone that plays a key role in the female reproductive system. It works by acting on the uterine lining (endometrium), helping it grow and maintain a suitable environment.
The medicine supports the transition of the uterine lining into a phase that is essential for normal menstrual cycles. It also helps counterbalance the effects of estrogen, thereby maintaining hormonal equilibrium. By providing a steady release of progesterone, the SR formulation ensures consistent hormonal support, which is important in managing conditions related to progesterone deficiency.
How to use SUSTEN SR 200MG TABLET
How to Take Susten SR 200mg Tablet
- Take the tablet after food to improve comfort
- Swallow whole with a glass of water; do not crush or chew
- Take it at the same time each day for consistency
- Follow the exact dose and duration prescribed
- Do not stop the medicine without medical advice
- Use regularly for best hormonal support
What if I forgot to take SUSTEN SR 200MG TABLET
- Take the missed dose as soon as you remember
- Skip it if it is close to the next dose
- Do not take a double dose
- Continue with your regular schedule
- Maintain consistency for better results
Overdose
Taking more than the prescribed dose may cause symptoms such as dizziness, drowsiness, nausea, or hormonal imbalance. Seek medical attention immediately if overdose is suspected.
Side Effects Of SUSTEN SR 200MG TABLET
Common
Common side effects of Susten SR 200mg Tablet
- Dizziness
- Headache
- Nausea
- Breast tenderness
- Abdominal discomfort
- Mood changes
When to Seek Medical Attention?
Stop taking the medicine and consult your doctor if you notice
- Unusual vaginal bleeding
- Severe headache or vision changes
- Swelling in legs or chest discomfort
- Persistent dizziness or fainting
- Signs of allergic reaction (rash, swelling, breathing difficulty)
How To Manage Side Effects
Dizziness Or Drowsiness
- Sit or lie down immediately: Rest in a safe position and avoid sudden movements. This helps prevent falls.
- Drink water or fluids: Dehydration is a common cause of dizziness. Sip water slowly or take oral rehydration fluids.
- Ginger: Ginger tea or a small piece of ginger can help ease dizziness and nausea in some people.
- Deep, slow breathing: Sit comfortably and take slow, deep breaths to help improve oxygen flow.
- Elevate your legs: Lying down with legs slightly raised can help improve blood flow to the brain.
- Eat light, balanced meals: Low blood sugar can cause dizziness. Small, frequent meals may help.
- Avoid sudden position changes: Stand up slowly from sitting or lying positions to prevent light-headedness.
- Limit caffeine and alcohol: These can worsen dizziness in some people.
Nausea And Vomiting
- Ginger: Sip ginger tea or chew small pieces of fresh ginger. Ginger has natural properties that may help soothe the stomach.
- Peppermint: Peppermint tea or inhaling peppermint aroma can help reduce nausea.
- Small, Frequent Meals: Eat light, bland foods like crackers, toast, or rice instead of heavy meals.
- Stay Hydrated: Take small sips of water, clear soups, or electrolyte drinks to prevent dehydration.
- Lemon: Smelling fresh lemon or sipping lemon water may help reduce queasiness.
- Fresh Air: Go for short walks outside or sit near a window to get fresh air.
- Avoid Strong Odors: Stay away from cooking smells, perfumes, or smoke, which may trigger nausea.
- Rest: Sit or lie down in a calm, quiet environment and avoid sudden movements.
Warning & Precautions
Pregnancy
Consult your doctorSusten SR 200mg Tablet may be used during pregnancy only if prescribed. Your doctor will assess the need based on individual condition.
Breastfeeding
Use with CautionSusten SR 200mg Tablet should be used with caution during breastfeeding. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionSusten SR 200mg Tablet may cause dizziness or drowsiness. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by Susten SR 200mg Tablet
Liver
Consult your doctorSusten SR 200mg Tablet should be used with caution in patients with liver conditions and it is not recommended in patients with severe liver disease. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take Susten SR 200mg Tablet if you are allergic to progesterone or any other inactive ingredients present in the medicine.
Use In Pediatrics
ContraindicatedSusten SR 200mg Tablet is not recommended for children unless specifically prescribed.
Use In Geriatrics
Use with CautionSusten SR 200mg Tablet should be used cautiously in elderly women, especially with underlying conditions. Consult your doctor before taking it.
Other Warnings for SUSTEN SR 200MG TABLET
Before taking Susten SR 200mg Tablet, inform your doctor if you
- Have a history of blood clots
- Have hormone-sensitive conditions
- Experience unexplained vaginal bleeding
Who should not take SUSTEN SR 200MG TABLET
Susten SR 200mg Tablet is not recommended if you
- Have a history of breast cancer or hormone-dependent tumors
- Have unexplained vaginal bleeding
- Have a history of blood clots
Safety Advice
- Use only on medical advice: Take Susten SR 200mg Tablet strictly as prescribed. Hormonal medicines should not be self-used or adjusted without consulting a doctor.
- Maintain consistent timing: Take the tablet at the same time every day to maintain stable progesterone levels and improve effectiveness.
- Take after food: Consuming it after meals helps reduce stomach discomfort and improves tolerance.
- Do not stop suddenly: Avoid discontinuing the medicine abruptly, as it may disturb hormonal balance. Always follow your doctor’s instructions.
- Be cautious with dizziness or drowsiness: This medicine may cause dizziness or sleepiness in some individuals. Avoid driving or operating machinery if you feel affected.
- Inform about medical history: Tell your doctor if you have a history of liver problems, blood clots, breast conditions, or unexplained vaginal bleeding.
- Watch for unusual symptoms: Seek medical advice if you notice severe headache, vision problems, swelling, chest pain, or abnormal bleeding.
- Regular follow-up is important: Attend scheduled check-ups so your doctor can monitor your response and adjust the dose if needed.
- Do not share your medicine: This tablet is prescribed based on individual hormonal needs. Do not share it with others.
Diet and Lifestyle Advice
- Take the tablet with food: Have it after a meal to improve comfort and support better absorption. A light, balanced meal works best.
- Maintain a balanced diet: Include whole grains, fruits, vegetables, nuts, seeds, and protein-rich foods (like dal, eggs, or lean meats) to support overall hormonal health.
- Include healthy fats: Foods like nuts, seeds, olive oil, and fatty fish help support hormone balance and overall well-being.
- Stay well hydrated: Drink plenty of water throughout the day to support metabolism and reduce chances of headache or fatigue.
- Include probiotic foods: Curd, yogurt, and fermented foods may help maintain gut balance and reduce digestive discomfort.
- Limit sugary and processed foods: Excess sugar and packaged foods may affect hormonal balance and overall health.
- Engage in regular physical activity: Light to moderate exercise such as walking, yoga, or stretching helps improve circulation and supports hormonal stability.
- Manage stress effectively: Practice relaxation techniques like meditation, deep breathing, or mindfulness to support hormonal balance.
- Get adequate sleep: Aim for 7–8 hours of quality sleep daily, as proper rest is essential for hormone regulation.
- Maintain a healthy body weight: Keeping a stable weight helps in better hormonal functioning and overall reproductive health.
- Track your menstrual cycle: Keeping a record of your cycle can help monitor progress and identify any irregularities early.
- Avoid smoking: Smoking may negatively impact hormonal balance and overall reproductive health.
- Follow a consistent routine: Taking your medicine and meals at regular times helps improve effectiveness and supports your body’s natural rhythm.
1 .Susten SR 200mg Tablet vs Dydrogesterone
|
Parameter |
Susten SR 200 mg (Micronized Progesterone) |
Dydrogesterone (e.g., Duphaston) |
|
Type of Hormone |
Natural, bioidentical micronized progesterone |
Synthetic progesterone analogue (progestin) |
|
Formulation |
Sustained-release oral tablet (200 mg) for gradual, steady hormone release |
Immediate-release oral tablet (commonly 10 mg) |
|
Mechanism of Action |
Mimics natural progesterone; stabilizes endometrium, supports implantation and pregnancy, reduces uterine contractions |
Selective progesterone receptor agonist with strong endometrial transformation and minimal systemic hormonal effects |
|
Absorption & Pharmacokinetics |
Variable absorption; affected by fat metabolism; sustained-release provides prolonged levels; may cause sedation due to metabolites |
High and predictable absorption; rapid onset; consistent bioavailability; does not produce sedative metabolites |
|
Common Uses |
Luteal phase defect, IVF support, threatened miscarriage, HRT (menopause), irregular cycles, PMS |
Threatened miscarriage, recurrent miscarriage, irregular cycles, endometriosis, PMS, luteal phase defects |
|
Effectiveness in Pregnancy Support |
Very effective; widely used in IVF and early pregnancy for luteal support |
Strong clinical evidence for threatened and recurrent miscarriage; often preferred |
|
Side Effects |
Drowsiness, dizziness, bloating, breast tenderness due to neuroactive metabolites |
Headache, mild nausea, breast tenderness; generally better daytime tolerability |
|
Dosing Convenience |
Usually once daily at night (due to sedative effect) |
Usually 1–3 times daily, but well tolerated because it does not cause drowsiness |
|
Ideal Patient Profile |
Suitable for women who prefer natural/bioidentical hormones, HRT users, and those comfortable with night dosing |
Suitable for women needing predictable, non-sedating daytime progesterone, especially in miscarriage or cycle-regulation treatments |
Drug - Drug interaction
1. Antiepileptic Medicines (e.g., phenytoin, carbamazepine)
- Interaction: These medicines may increase the breakdown of progesterone in the liver, reducing its effectiveness.
- Management: Dose adjustment may be required. Use only under medical supervision and report reduced effectiveness.
2. Antibiotics (e.g., rifampicin)
- Interaction: Certain antibiotics can reduce progesterone levels by increasing its metabolism, potentially lowering its effect.
- Management: Your doctor may adjust the dose or monitor response. Do not combine without medical advice.
3. Antifungal Medicines (e.g., ketoconazole)
- Interaction: These medicines may increase progesterone levels in the body, raising the risk of side effects such as dizziness or drowsiness.
- Management: Use cautiously under supervision. Report any unusual symptoms promptly.
4. Other Hormonal Therapies (e.g., estrogen, oral contraceptives)
- Interaction: Combining with other hormones may alter hormonal balance and lead to unpredictable effects.
- Management: Should be used only if prescribed together. Regular monitoring may be required.
5. Sedatives and CNS Depressants (e.g., benzodiazepines, sleeping pills)
- Interaction: May increase drowsiness, dizziness, or reduced alertness when taken with progesterone.
- Management: Avoid activities requiring alertness (like driving). Use cautiously and only if advised.
6. Thyroid Medicines (e.g., levothyroxine)
- Interaction: Progesterone may influence thyroid hormone levels indirectly in some individuals.
- Management: Periodic thyroid function monitoring may be recommended.
7. Corticosteroids (e.g., prednisolone)
- Interaction: May alter the metabolism or effects of progesterone, depending on dose and duration.
- Management: Use under supervision. Dose adjustments may be needed.
8. Herbal Supplements (e.g., St. John’s Wort)
- Interaction: May increase the breakdown of progesterone, reducing its effectiveness.
- Management: Avoid self-use of herbal supplements without informing your doctor.
9. Antidiabetic Medicines
- Interaction: Hormonal changes may slightly affect blood sugar control in some individuals.
- Management: Monitor blood glucose levels regularly and consult your doctor if changes are noticed.
Drug - Food interaction
1. Food (General Meals)
- Interaction: Taking progesterone with food can improve its absorption and reduce stomach discomfort.
- Management: Always take Susten SR 200mg Tablet after a meal or with a light snack for better tolerance and effectiveness.
2. High-Fat Meals
- Interaction: Fat-rich meals may increase the absorption of progesterone, which can sometimes enhance its effects or side effects like drowsiness.
- Management: Prefer a balanced meal instead of very heavy or oily foods when taking the tablet.
3. Caffeine (Tea, Coffee, Energy Drinks)
- Interaction: Excess caffeine may worsen symptoms like restlessness, headache, or sleep disturbances in some individuals.
- Management: Limit caffeine intake and observe how your body responds.
4. Grapefruit and Grapefruit Juice
- Interaction: Grapefruit may affect enzymes that metabolize hormones, potentially increasing progesterone levels in the body.
- Management: Avoid or limit grapefruit products unless your doctor advises otherwise.
5. Probiotic Foods (Curd, Yogurt, Fermented Foods)
- Interaction: These foods do not directly affect progesterone but may help reduce digestive discomfort and support gut health.
- Management: Including probiotic-rich foods can be beneficial during therapy.
6. Sugary and Processed Foods
- Interaction: Excess sugar and processed foods may indirectly affect hormonal balance and overall well-being.
- Management: Limit intake and prefer fresh, whole foods for better hormonal support.
Synopsis
|
Drug |
Progesterone |
|
Pharmacological Category |
Hormone (Progestogen) |
|
Therapeutic Indication |
Supports hormonal balance |
|
Dosage Forms |
Tablet, Capsule, Injection |
More Information
FAQs About SUSTEN SR 200MG TABLET
Q: What is Susten SR 200mg Tablet used for?
A: It is commonly used to support hormonal balance in women with low progesterone levels. It helps regulate menstrual cycles and supports reproductive health. It is prescribed based on individual needs. Use it only under medical guidance.
Q: Can I take Susten SR on an empty stomach?
A: It is better to take it after food. This helps improve comfort and absorption. Taking it with meals may reduce stomach discomfort. Follow your doctors advice for best results.
Q: What are the common side effects?
A: Common side effects include dizziness, headache, nausea, and breast tenderness. These are usually mild and temporary. Taking the medicine as directed helps reduce discomfort. Consult your doctor if symptoms persist.
Q: Can Susten SR cause drowsiness?
A: Yes, some people may feel drowsy or dizzy. Avoid driving or operating machinery if affected. Rest well and stay hydrated. Inform your doctor if symptoms continue.
Q: Is Susten SR safe during pregnancy?
A: It may be used during pregnancy if prescribed. Your doctor will decide based on your condition. Do not take it without medical advice. Always follow prescribed guidelines.
Q: Can Susten SR affect menstrual cycles?
A: Yes, it helps regulate menstrual cycles by supporting hormone balance. It is often used in irregular periods. Regular use improves cycle consistency. Follow your doctors instructions.
Q: Who should avoid Susten SR?
A: Women with hormone-sensitive conditions, liver disease, or unexplained bleeding should avoid it. Inform your doctor about your medical history. Use only if prescribed.
Q: Can I stop taking Susten SR suddenly?
A: No, do not stop suddenly without consulting your doctor. It may affect hormone levels. Always follow the prescribed course. Seek advice before making changes.
Q: Can Susten SR be taken with other medicines?
A: Yes, but interactions may occur. Inform your doctor about all medicines you are taking. This helps avoid unwanted effects. Follow medical guidance carefully.
Q: What should I do if I miss a dose?
A: Take it as soon as you remember. Skip if the next dose is near. Do not double the dose. Continue your regular schedule.
References
1. KD. Tripathi. Estrogens, Progestins, and Contraceptives. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 316.
2. Michaela Jewson, Prashant Purohit, Mary Ann Lumsden. Progesterone and abnormal uterine bleeding/menstrual disorders. ScienceDirect. [Revised in November 2020]. [Accessed on 24th March 2026] ![]()
3. R Erny, A Pigne, C Prouvost, M Gamerre, C Malet, H Serment, J Barrat. The effects of oral administration of progesterone for premature labor. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. [Revised in March 1986]. [Accessed on 24th March 2026] 
4. Catalent Pharma Solutions. U.S. Food & Drug Administration. [Accessed on 24th March 2026] 
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