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Introduction About SUPPOL 250MG SUPPOSITORY
SUPPOL 250MG SUPPOSITORY contains Paracetamol which belongs to the group of medicines called Analgesics and Antipyretics. It is used to manage pain and fever (high temperature) in children (from 3 months to 12 years of age) who find it difficult to take the medicine orally.
Before administering SUPPOL 250MG SUPPOSITORY to your child, inform the child’s doctor if your child has liver or kidney problems or any allergies. Do not give your child medicines containing alcohol. Consult your child’s doctor for advice.
SUPPOL 250MG SUPPOSITORY is not recommended for use in elderly patients, pregnant and breastfeeding women as it is used only in children.
The most common side effect of using SUPPOL 250MG SUPPOSITORY is redness or soreness in and around the back passage. Consult your child’s doctor if any of the side effects get worse.
Uses Of SUPPOL 250MG SUPPOSITORY
- Manage pain and fever in children (from 3 months to 12 years of age), who finds it difficult to take the medicine orally
How SUPPOL 250MG SUPPOSITORY Works
SUPPOL 250MG SUPPOSITORY relieves pain by increasing the pain threshold by inhibiting certain enzymes (COX-1 and COX-2) involved in the synthesis of chemicals responsible for inducing pain (prostaglandins). It reduces fever by directly acting on heat-regulating centers in the brain, resulting in vessel relaxation, sweating and loss of body heat.
How to use SUPPOL 250MG SUPPOSITORY
Administer SUPPOL 250MG SUPPOSITORY to your child as advised by the physician. It is for rectal use only. Your child’s bowel needs to be empty when you administer it. Wash your hands and peel the wrapping apart. Do not break the medicine before use. Smoothly push into the back passage of the child with the pointed end first. Slightly warm it between your hands beforehand to make it easier. Tell your child to keep still for a minute or two and then clean your hands.
Your child’s doctor will decide the correct dose and duration for your child based on the child’s age, body weight and disease condition.
Side Effects Of SUPPOL 250MG SUPPOSITORY
Uncommon
- redness or soreness in and around the back passage
Rare
- blood problems (bruising or bleeding more easily than usual, more susceptibility to infections, fever, ulcers in the mouth and throat)
- liver problems (yellow skin or whites of the eyes)
Stop administering SUPPOL 250MG SUPPOSITORY to your child and contact the doctor immediately if your child experiences any of the following side effects:
- allergic reaction (signs include rash, trouble swallowing or breathing, swelling of the lips, face, throat or tongue)
Warning & Precautions
Pregnancy
SUPPOL 250MG SUPPOSITORY is not recommended for use in pregnant women as it is used only in children. Consult your doctor for advice.
Breastfeeding
SUPPOL 250MG SUPPOSITORY is not recommended for use in breastfeeding women as it is used only in children. Consult your doctor for advice.
Alcohol
Do not give your child medicines containing alcohol. Consult the child’s doctor for advice before administering SUPPOL 250MG SUPPOSITORY to your child.
Kidney
SUPPOL 250MG SUPPOSITORY should be used with caution in children with kidney problems. Consult your child’s doctor for advice.
Liver
SUPPOL 250MG SUPPOSITORY should be used with caution in children with liver problems. Consult your child’s doctor for advice.
Allergy
Do not administer SUPPOL 250MG SUPPOSITORY to your child if they are allergic to Paracetamol, soya, peanuts or any other ingredients of this medicine.
Interactions
A. Drug - Drug interactions:
Before administering SUPPOL 250MG SUPPOSITORY to your child, inform to child’s doctor if your child is taking any of the following medicines:
- other medicines containing paracetamol
- medicines used to manage nausea and vomiting (Ex. metoclopramide, domperidone)
- cholestyramine (used to control blood lipid levels)
- medicines used to manage fits (Ex. carbamazepine, phenytoin)
- warfarin (used for managing blood clots)
- medicines containing alcohol
- medicines used to manage bacterial infections (Ex. rifampicin, flucloxacillin)
Overdosage:
If you have administered more SUPPOL 250MG SUPPOSITORY to your child accidentally, consult the child’s doctor immediately or visit the nearby hospital, even if the child feels well, as it can cause delayed serious liver damage.
Synopsis
| Drug | : | Paracetamol |
| Pharmacological Category | : | Para aminophenol derivative |
| Therapeutic Indication | : | Pain, Fever |
| Dosage Forms | : |
Tablet, Dispersible tablet, Drops, Syrup, Oral suspension, Liquid, Oral solution, Suppositories, Infusion, Injection |
More Information
- Keep SUPPOL 250MG SUPPOSITORY out of reach of children
- Store SUPPOL 250MG SUPPOSITORY below 25°C
FAQs About SUPPOL 250MG SUPPOSITORY
How does SUPPOL 250MG SUPPOSITORY work?
SUPPOL 250MG SUPPOSITORY relieves pain by increasing the pain threshold by inhibiting certain enzymes (COX-1 and COX-2) involved in the synthesis of chemicals responsible for inducing pain (prostaglandins). It reduces fever by directly acting on heat-regulating centers in the brain, resulting in vessel relaxation, sweating and loss of body heat.
What is SUPPOL 250MG SUPPOSITORY used for?
SUPPOL 250MG SUPPOSITORY contains Paracetamol which belongs to the group of medicines called Analgesics and Antipyretics. It is used to manage pain and fever (high temperature) in children (from 3 months to 12 years of age) who find it difficult to take the medicine orally.
How to administer SUPPOL 250MG SUPPOSITORY to my child?
Administer SUPPOL 250MG SUPPOSITORY to your child as advised by the physician. It is for rectal use only. Your child’s bowel needs to be empty when you administer it. Wash your hands and peel the wrapping apart. Do not break the medicine before use. Smoothly push into the back passage of the child with the pointed end first. Slightly warm it between your hands beforehand to make it easier. Tell your child to keep still for a minute or two and then clean your hands.
What happens if I accidentally administer an extra dose of SUPPOL 250MG SUPPOSITORY to my child?
If you have administered more SUPPOL 250MG SUPPOSITORY to your child accidentally, consult the child’s doctor immediately or visit the nearby hospital, even if the child feels well, as it can cause delayed serious liver damage.
Is SUPPOL 250MG SUPPOSITORY safe to use in children with liver problems?
SUPPOL 250MG SUPPOSITORY should be used with caution in children with liver problems. The child’s doctor may monitor the liver function test before and during management with this medicine to manage the risk of liver damage. Consult your child’s doctor for advice before administering SUPPOL 250MG SUPPOSITORY to your child.
References
1. Tilo Grosser, Emer Smyth and Garret A. FitzGerald. Anti-inflammatory, Antipyretic and Analgesic agents; Pharmacotherapy of gout. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 693.
2. Cullen, S., Kenny, D., Ward, O. C. and Sabra, K. Paracetamol suppositories: a comparative study. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. June 1989 [Accessed on 11th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1792788/pdf/archdisch00669-0096.pdf
3. Anderson BJ. Paracetamol (Acetaminophen): mechanisms of action. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. October 2008. [Accessed on 11th August 2022] https://pubmed.ncbi.nlm.nih.gov/18811827/#:~:text=Paracetamol%20has%20a%20central%20analgesic,active%20metabolite%20influencing%20cannabinoid%20receptors
4. Dr. Pfleger Arzneimittel GmbH. Electronic Medicines Compendium (EMC). [Revised in April 2022] [Accessed on 11th August 2022] https://www.medicines.org.uk/emc/files/pil.8081.pdf
5. P.P.F.Hasco-Lek SA. Health Products Regulatory Authority (HPRA). [Revised in May 2022] [Accessed on 11th August 2022] https://www.hpra.ie/img/uploaded/swedocuments/1e4e0177-c592-42ba-a4ae-9765eeb10293.pdf
6. Dr. Pfleger Arzneimittel GmbH. Paracetamol 125 mg Suppositories. [Revised in April 2022] [Accessed on 11th August 2022] https://www.typharm.com/wp-content/uploads/2022/06/Paracetamol-125mg-Supps-Currently-Approved-Leaflet_29_04_22.pdf
Useful Diagnostic Tests
- Complete blood count
- Liver function test
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