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Introduction About SRFIL ENEMA
SRFIL ENEMA contains Sucralfate, which belongs to the group of medicines called Antiulcer agents. It is used to manage hemorrhagic radiation proctitis (inflammation of the rectum due to radiotherapy in the lower part of the abdomen), solitary rectal ulcer syndrome (ulcers in the rectum) and diversion colitis.
Diversion colitis is an inflammation of the colon which can occur as a complication of ileostomy or colostomy. Before the management, your doctor may recommend you take relevant tests to understand your condition.
SRFIL ENEMA is not recommended for use in patients who have end-stage renal disease, and uncontrolled diabetes mellitus with hyperglycemia (high blood sugar). The safety and effectiveness of SRFIL ENEMA for use in pregnant women, breastfeeding mothers and infants have not been established yet. Contact your doctor before using it. The most common side effect of SRFIL ENEMA is constipation. Contact your doctor if the symptoms worsen.
Uses Of SRFIL ENEMA
Manage:
- Manage hemorrhagic radiation proctitis
- Manage solitary rectal ulcer syndrome
- Manage diversion colitis
How SRFIL ENEMA Works
SRFIL ENEMA works by forming a protective layer over the bowel wall and protects the fragile blood vessels from breaking. It increases growth factor production, promoting tissue growth and regeneration, thereby facilitating repair.
How to use SRFIL ENEMA
Use SRFIL ENEMA as advised by your physician. It is for Rectal use only. Your physician will decide the correct dose and duration for you depending on your age, body weight, and disease condition.
Side Effects Of SRFIL ENEMA
Common
- constipation
How To Manage Side Effects
Constipation:
Eat plenty of fiber-rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise regularly. Contact your doctor if your symptoms get worse or persist.
Warning & Precautions
Pregnancy
The safety and effectiveness of SRFIL ENEMA for use by pregnant women or women planning to have a baby has not been established. Contact your doctor before using it.
Breastfeeding
The safety and effectiveness of SRFIL ENEMA for use by breastfeeding women have not been established. Contact your doctor before using it.
Kidney
SRFIL ENEMA should be used with caution in patients with kidney disease on dialysis. SRFIL ENEMA is not recommended for use in patients with end-stage kidney disease. Contact your doctor before using it.
Allergy
Do not apply SRFIL ENEMA if you are allergic to Sucralfate or any of the other ingredients of this medicine.
Others
SRFIL ENEMA is not recommended for use if you have:
- uncontrolled diabetes mellitus with hyperglycemia (high blood sugar)
Use in Pediatrics:
The safety and effectiveness of SRFIL ENEMA for use in infants have not been established. Contact your doctor before using it.
Interactions
A. Drug-Drug interactions:
Before using SRFIL ENEMA, inform your doctor if you are taking any of the following medicine:
- naproxen (to relieve pain)
- potassium phosphate (manages low levels of phosphorus)
- levoketoconazole (to manage high cortisol levels)
- deferasirox (to manage iron overload in the body)
- baloxavir (manages influenza)
- digoxin (manages heart failure)
- levothyroxine (manages low thyroid hormone)
- furosemide (to reduce swelling caused by too much water in the body)
- quinolones (Ex. ofloxacin, ciprofloxacin) manage the bacterial infection
- warfarin (prevents blood clots)
- antiretrovirals like raltegravir (manages HIV/AIDS)
- bisphosphonates (Ex. ibandronate, risedronate) to manage bone loss
- multivitamins
- antacids (Ex. magnesium hydroxide, calcium carbonate)
Overdosage:
If you or anyone else accidentally use too much of this medicine, consult your physician immediately.
Synopsis
| Drug | : | Sucralfate |
| Pharmacological Category | : | Anti-ulcer |
| Therapeutic Indication | : | gastric duodenal and benign ulcers |
| Dosage Forms | : | Tablet, Diskettes, Enema, Syrup, Suspension, Cream, Oral solution, Oral suspension, Solution, Syrup, Oral gel, Gel |
More Information
- Keep out of reach from children
- Store at a room temperature of 20 to 25°C
FAQs About SRFIL ENEMA
What is the use of SRFIL ENEMA?
It is used to manage hemorrhagic radiation proctitis (inflammation of the rectum due to radiotherapy in the lower part of the abdomen), solitary rectal ulcer syndrome (ulcers in the rectum) and diversion colitis.
What is the mechanism of action of SRFIL ENEMA?
SRFIL ENEMA works by forming a protective layer over the bowel wall and protects the fragile blood vessels from breaking. It increases growth factor production, promoting tissue growth and regeneration, thereby facilitating repair.
SRFIL ENEMA can be used in patients with kidney problems?
SRFIL ENEMA should be used with caution in patients with kidney disease on dialysis.
SRFIL ENEMA is not recommended for use in patients with end-stage kidney disease. Contact your doctor before using it.
Is SRFIL ENEMA safe for use in pregnant and breastfeeding women?
The safety and effectiveness of SRFIL ENEMA for use in pregnant women or women planning to have a baby and breastfeeding woman has not been established. Contact your doctor before using it.
What are the contraindications of SRFIL ENEMA?
It is not recommended for use in patients who have end-stage renal disease, and uncontrolled diabetes mellitus with hyperglycemia (high blood sugar). Consult your doctor before using it.
References
1. KD Tripathi. Drug for Peptic Ulcer and Gastroesophageal Reflux Disease. Essentials of medical pharmacology. Seventh edition. 2013. Page – 656.
2. Pujitha Kudaravalli; Savio John. Sucralfate. NIH National Library of Medicine, National center for biotechnology information. [Revised in February 2022] [Accessed on 18th October 2022] https://www.ncbi.nlm.nih.gov/books/NBK551527/
3. K McElvanna, A Wilson, T Irwin. Sucralfate paste enema: a new method of topical treatment for hemorrhagic radiation proctitis. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. April 2014. [Accessed on 18th October 2022] https://pubmed.ncbi.nlm.nih.gov/24299100/
4. R Kochhar, S K Mehta, R Aggarwal, A Dhar, F Patel. Sucralfate enema in ulcerative rectosigmoid lesions. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov January 1990. [Accessed on 18th October 2022] https://pubmed.ncbi.nlm.nih.gov/2295277/
5. Sucralfate. The Royal Marsden NHS Foundation Trust. [Revised in January 2021] [Accessed on 18th October 2022] https://patientinfolibrary.royalmarsden.nhs.uk/document/download/1171
Useful Diagnostic Tests
- Helicobacter Pylori IgA
- Helicobacter Pylori IgG
- Helicobacter Pylori IgM
- Kidney function test
- Blood tests
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