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Introduction About SPIRODIN AB TABLET
SPIRODIN AB TABLET is a combination of Acebrophylline and Doxofylline, which belongs to the group of medicines called Bronchodilators. It is used to manage asthma, chronic obstructive pulmonary disease (COPD), and bronchitis. It can also be used to reduce apnea (lack of breathing) and other respiratory diseases associated with bronchospasm (tightening of airways).
Asthma is a long-term respiratory disease in which your airways become inflamed, swollen, and narrowed. It also causes excessive mucous secretion in the airways, which makes it difficult for the air to pass through, leading to unpleasant symptoms like wheezing, difficulty breathing, chest pain, and/or cough.
COPD is a lung disease characterized by chronic lung inflammation and obstructed airflow within the airways. It causes wheezing, breathing difficulties, coughing with mucus production, and chest pain.
Before taking SPIRODIN AB TABLET, inform your doctor if you have any liver, kidney, or heart problems. You must also inform your doctor if you have hypertension, hyperthyroidism, stomach ulcers, or any concomitant infections as a precaution.
SPIRODIN AB TABLET is not recommended for use in patients with severe hypotension or heart problems (such as myocardial infarction). It is also not suitable for use in pregnant or breastfeeding women.
The most common side effects of taking SPIRODIN AB TABLET are nausea, vomiting, upper stomach pain, irritability, lack of sleep, and fast heartbeat or breathing. Consult your doctor if any of these side effects worsen.
Uses Of SPIRODIN AB TABLET
It is used to manage:
- Bronchial Asthma
- Chronic Obstructive Pulmonary Disease (COPD)
- Bronchitis
- Apnea (breathing stops for a brief period)
How SPIRODIN AB TABLET Works
SPIRODIN AB TABLET is a bronchodilator. It relaxes the smooth muscles of the airways by blocking the release of certain enzymes (phosphodiesterase) in the respiratory tract that triggers narrowing. As a result, it widens the airways, allows the air to pass through more freely, and makes breathing easier.
How to use SPIRODIN AB TABLET
Take SPIRODIN AB TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Your doctor will decide the correct dose, duration of therapy, and number of doses per day depending upon your age, body weight, and disease condition.
Do not stop taking SPIRODIN AB TABLET once your symptoms subside without consulting your doctor.
Side Effects Of SPIRODIN AB TABLET
Common
- nausea, vomiting
- upper stomach pain, heartburn, loss of appetite
- transient nausea, dizziness, drowsiness
- skin rash or itching
- breathing difficulties
- nasal inflammation
- headache
- irritability
- lack of sleep (insomnia)
- abnormal or rapid heartbeat
- fast breathing
Rare
- hyperglycemia (high blood sugar levels)
- albuminuria (presence of albumin in urine)
Stop taking SPIRODIN AB TABLET and consult your doctor immediately if you experience any of the following side effects:
- cardiac arrhythmias
- fits (tonic-clonic seizures)
How To Manage Side Effects
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids, such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Nausea And Vomiting
Take SPIRODIN AB TABLET with or just after meals. Stick to simple meals. Avoid eating oil-rich or spicy foods. Consult your doctor if your nausea and vomiting worsen.
Warning & Precautions
Pregnancy
ContraindicatedSPIRODIN AB TABLET is not recommended for use in pregnancy. Therefore, consult your doctor before taking it.
Breastfeeding
ContraindicatedSPIRODIN AB TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.
Driving and Using Machines
Use with CautionSPIRODIN AB TABLET usually does not affect your ability to drive or operate any machinery. However, do not drive or handle any heavy tools or machines if you feel dizzy or drowsy after taking SPIRODIN AB TABLET.
Kidney
Use with CautionSPIRODIN AB TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
Liver
Use with CautionSPIRODIN AB TABLET should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.
Allergy
ContraindicatedTalk to your doctor before taking SPIRODIN AB TABLET if you are allergic to acebrophylline, doxofylline, or any other similar medicines (such as etophylline, aminophylline).
Heart Disease
Consult your doctorSPIRODIN AB TABLET is not recommended for use in patients suffering from myocardial infarction or arrythmias. It should be used with caution in patients with heart failure or any other heart problems. Therefore, consult your doctor before taking it.
Use In Pediatrics
ContraindicatedSPIRODIN AB TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
Use In Geriatrics
Use with CautionSPIRODIN AB TABLET should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before taking it.
Others
SPIRODIN AB TABLET is not recommended for use if you:
- have severe hypotension (low blood pressure)
- have fluid and electrolyte imbalance
Before taking SPIRODIN AB TABLET, tell your doctor if you:
- have concomitant infections (such as viral infections)
- have hypertension (high blood pressure)
- have severe hypoxemia (low oxygen levels in the blood)
- have chronic cor pulmonale (the right side of the heart fails to function properly)
- have peptic ulcer
- have chronic alcoholism (addiction to alcohol)
- have an overactive thyroid gland
- have fits (seizures)
Interactions
A. Drug-Drug Interactions:
Before taking SPIRODIN AB TABLET, inform your doctor if you are taking any of the following medicines, such as:
- other methylxanthines (used to manage respiratory problems) Ex. etophylline, aminophylline
- medicines used to manage bacterial infections (such as erythromycin, ciprofloxacin, doxycycline, amoxicillin, troleandomycin, lincomycin, and clindamycin)
- allopurinol (a medicine used to manage gout)
- cimetidine (a medicine used to manage stomach ulcers)
- influenza vaccine
- propranolol (a medicine used to manage heart problems)
- phenytoin (a medicine used to manage fits)
- sympathomimetic drugs (medicines used to increase heart rate and hypertension) Ex. ephedrine
- corticosteroids (used to manage pain and inflammation) such as prednisolone
- diltiazem, verapamil (a medicine used to manage heart problems)
- frusemide (a medicine used to reduce edema and blood pressure by increasing urine output)
- isoprenaline (a medicine used to manage a slow heart rate)
- oral contraceptives (birth control pills) such as ethinylestradiol
- thiabendazole (a medicine used to manage worm infections)
B. Drug-Food Interactions:
Limit the consumption of foods and beverages rich in caffeine (such as coffee) while taking SPIRODIN AB TABLET.
Overdosage:
If you or anyone else accidentally took more SPIRODIN AB TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of an overdose might include stomach pain, restlessness, and fits.
Synopsis
| Drug | : | Acebrophylline, Doxofylline |
| Pharmacological Category | : | Methylxanthines |
| Therapeutic Indication | : | Bronchial Asthma, Chronic Obstructive Pulmonary Disease, Apnea, Bronchitis |
| Dosage Forms | : | Tablet |
More Information
Storage
- Keep SPIRODIN AB TABLET out of reach of children
- Store SPIRODIN AB TABLET at room temperature
FAQs About SPIRODIN AB TABLET
Q: How SPIRODIN AB TABLET works?
A: SPIRODIN AB TABLET is a bronchodilator. It relaxes the smooth muscles of the airways by blocking the release of certain enzymes (phosphodiesterase) in the respiratory tract that triggers narrowing. As a result, it widens the airways, allows the air to pass through more freely, and makes breathing easier.
Q: What is the use of SPIRODIN AB TABLET?
A: SPIRODIN AB TABLET is used to manage asthma, chronic obstructive pulmonary disease (COPD), and bronchitis. It can also be used to reduce apnea (lack of breathing) and other respiratory diseases associated with bronchospasm (tightening of airways).
Q: Can I take SPIRODIN AB TABLET daily?
A: SPIRODIN AB TABLET is generally prescribed as two or three doses per day. However, your doctor will decide the number of doses per day depending upon your age, body weight, and disease condition.
Q: Is SPIRODIN AB TABLET effective?
A: Yes. SPIRODIN AB TABLET effectively controls the symptoms of asthma, COPD, and other breathing problems by relaxing the smooth muscles of the airways. This action widens the airways, allows the air to pass through more freely, and makes breathing easier.
Q: What will happen if I consume a higher dose of SPIRODIN AB TABLET than prescribed by my doctor?
A: Do not consume a higher dose of SPIRODIN AB TABLET than the one prescribed by your doctor, as it may lead to unwanted side effects. Your doctor will decide the correct dose for you, depending on your age and disease condition. If the prescribed dose is not working for you, consult your doctor for advice.
Q: Is SPIRODIN AB TABLET safe?
A: SPIRODIN AB TABLET is considered safe at doses prescribed by the physician. However, it may cause a few side effects, such as stomach pain, headache, nausea, vomiting, irritability, lack of sleep, or fast breathing or heart rate in some individuals. Contact your doctor if they bother you.
Q: What should I do if I forgot to take a dose of SPIRODIN AB TABLET?
A: If you forgot to take a dose of SPIRODIN AB TABLET, take it as soon as possible. However, if it is time to take the next dose, skip the missed dose and take the next one at regular times. Do not take a double dose of SPIRODIN AB TABLET to compensate for the missed dose.
Q: Will taking a higher dose of SPIRODIN AB TABLET be more effective?
A: No. Do not take a higher dose of SPIRODIN AB TABLET than prescribed by your doctor, as it could lead to toxicity. Always consume the dose prescribed by your doctor. If you feel that the prescribed dose is not working for you, consult your doctor for advice.
Q: Is SPIRODIN AB TABLET safe during pregnancy?
A: SPIRODIN AB TABLET is not recommended for use in pregnancy. Therefore, consult your doctor before taking it.
Q: Can SPIRODIN AB TABLET be used in children?
A: SPIRODIN AB TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
Q: Can I stop using SPIRODIN AB TABLET once my symptoms subside?
A: No. Continue to use SPIRODIN AB TABLET as long as your doctor prescribes it to you. Do not stop using this medicine or reduce the dose suddenly without consulting your doctor, as it may make it less effective.
Q: Can SPIRODIN AB TABLET be used on an asthma attack?
A: No. SPIRODIN AB TABLET is only used to manage the symptoms of asthma. If your asthma or breathing gets worse suddenly, contact your doctor immediately or go to the hospital straight away to avoid further exacerbation of the attack. Meanwhile, use a fast-acting rescue inhaler to manage your condition.
Q: How to take SPIRODIN AB TABLET?
A: Take SPIRODIN AB TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Q: What are the side effects of taking SPIRODIN AB TABLET?
A: The most common side effects of taking SPIRODIN AB TABLET are nausea, vomiting, upper stomach pain, irritability, lack of sleep, and fast heartbeat or breathing. Consult your doctor if any of these side effects worsen.
References
1. KD. Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 224-227.
2. Paola Rogliani, Luigino Calzetta, Josuel Ora, Mario Cazzola, and Maria Gabriella Matera. Efficacy and safety profile of doxofylline compared to theophylline in asthma: a meta-analysis. BMC. Multidisciplinary Respiratory Medicine. August 2019. [Accessed on 13th September 2024]. https://mrmjournal.biomedcentral.com/articles/10.1186/s40248-019-0189-0
3. Sumit Roy Tapadar, Maumita Das, Arunabha Datta Chaudhuri, Santanu Basak, and Anil Baran Singha Mahapatra. The Effect of Acebrophylline vs. Sustained Release Theophylline in Patients of COPD- A Comparative Study. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. September 2014. [Accessed on 13th September 2024]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225926/
4. Cipla Ltd. Mucophylin Capsules (Acebrophylline). [Revised in November 2013] [Accessed on 13th September 2024]. https://www.ciplamed.com/product-index/mucophylin-capsules
5. A.B.C. Farmaceutici S.P.A. Doxofylline. [Revised in March 2011] [Accessed on 13th September 2024]. https://www.abcfarmaceutici.it/uploads/news/40_file3_en.pdf
6. Central Drugs Standard Control Organization (CDSCO). Doxofylline MR Tablet 650 mg. Doxofylline Tablet (400 mg) and Doxofylline Tablets & Syrup. [Accessed on 13th September 2024]. https://cdscoonline.gov.in/CDSCO/Drugs
7. Central Drugs Standard Control Organization. Acebrophylline capsules 100 mg. May 2008. Acebrophylline SR Tablet 200 mg. November 2010. [Accessed on 13th September 2024]. https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadApprovalMarketingFDC/LIST%20OF%20APPROVED%20DRUG%20FROM%2001-01-2008%20to%2031-12-2008.pdf
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Total IGE
- Wheeze/Rhinitis Comprehensive Panel Adult
- Basic Allergy Package
- Absolute Eosinophil Count, Blood
- Allergy Comprehensive Profile
- Allergy Post Screening Profile
- Allergy Screen (Includes Total Ige And Alatop)
- Infection Checkup Profile
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