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Introduction About SORVATE OINTMENT
SORVATE OINTMENT contains Calcipotriol which belongs to group of medicines called Anti-psoriatics. SORVATE OINTMENT is used to manage plaque psoriasis (long-lasting autoimmune disease that cause thicky scaly patches on skin) in affected individuals.
SORVATE OINTMENT is not recommended for use in patients allergic to Calcipotriol. It is also not recommended for use in patients with a history of hypersensitivity reaction (immune response to an allergen), calcium metabolism disorders (due to high/low calcium levels), vitamin D toxicity, and/or severe liver & kidney disease.
Before applying SORVATE OINTMENT, inform your doctor if you are a smoker, undergoing ultraviolet management, and/or suffering from exfoliative/pustular psoriasis.
[GBNKEYWORLD] should be used with caution during pregnancy only if it is clearly necessary. It is also used with caution in breastfeeding women which is advised not to apply on breast area while feeding the baby.
SORVATE OINTMENT is not recommended for use in children (aged below 6 years) and is advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor.
The most common side effects of applying SORVATE OINTMENT are pain at the site of application, burning/stinging sensation, skin irritation, itching, itchy rash, and skin redness. Consult your doctor if any of these symptoms worsens.
Uses Of SORVATE OINTMENT
- Manage plaque psoriasis in affected individuals
How SORVATE OINTMENT Works
SORVATE OINTMENT works by inhibiting cell growth and its development without causing any harm to the cell which results in decreased growth of abnormal cells thus controlling psoriatic condition and managing the condition in affected individuals.
How to use SORVATE OINTMENT
Always apply SORVATE OINTMENT as directed by your physician. It is for external use only. Apply a thin layer of this medicine on the affected area. Managed areas on the face need not be covered with a plaster or bandage. Do not use this medicine on your face.
Side Effects Of SORVATE OINTMENT
Common
- pain at the site of application
- burning/stinging sensation
- skin irritation
- itching
- itchy rash
- skin redness
- dry skin
- peeling skin
- dermatitis (skin inflammation)
- worsening of psoriasis
Uncommon
- skin atrophy (thin skin)
- hyperpigmentation (darkened patches or spots on the skin)
- signs of hypercalcemia (high calcium level in blood) frequent urination, thirst, weakness, bone pain
- folliculitis (inflammation of hair follicle)
- red, itchy, scaly rash
- blisters may form on skin
- changes in skin colour where the medicine is used
Rare
- signs hypersensitivity reaction (immune response to an allergen) such as rash, itching, watery eyes, coughing/sneezing
- temporary increased sensitivity to sunlight
- skin swelling or puffiness
- itchy raised rash
- seborrheic dermatitis such as dandruff or cradle cap
- signs of hypercalciuria (excess calcium in the urine) such as pain while urination, lower abdominal pain
Stop taking SORVATE OINTMENT and contact your doctor immediately if:
- signs of hypercalcemia (excess calcium in blood) and hypercalciuria (excess calcium in the urine) such as increased urinary frequency, excessive thirst, loss of appetite, dry/metallic taste in the mouth, stomach upsets (includes pain, nausea, vomiting and constipation), weak muscles and/or pain in the bones, tiredness, fatigue, confusion, feeling sick and constipation
- signs of allergic reactions such as difficulty while breathing, swelling of face including eyes, severe skin rash (particularly blistering or bleeding)
How To Manage Side Effects
Dry Skin:
Try moisturizing your skin with an ointment, cream, or lotion 2 or 3 times a day, or as often as needed. Moisturizers help to keep the area moisture, so they work best on damp skin. After you bathe, pat your skin dry then apply your moisturizer. Try to avoid using skin care products and soaps that contain alcohol, fragrances, dyes, or other chemicals.
Itchy Skin:
Try to pat or tap your skin instead of scratching it. Hold a damp towel to cool your skin. Wear loose clothing and avoid tight clothes, or clothes made from wool or synthetic fabrics. Avoid using perfumed soaps, deodorants or moisturizers and use a skin softener regularly.
Warning & Precautions
Pregnancy
SORVATE OINTMENT should be used with caution in pregnant women only if it is clearly necessary. Consult your doctor before applying it.
Breastfeeding
SORVATE OINTMENT should be used with caution in breastfeeding women. It is not recommended to be applied on breast area while feeding the baby. Consult your doctor before applying the medicine.
Driving and Using Machines
SORVATE OINTMENT generally does not have any effect on your ability to drive or use machines. Consult your doctor before applying the medicine.
Kidney
SORVATE OINTMENT is not recommended for use in patients suffering from severe kidney problems. Consult your doctor before applying the medicine.
Liver
SORVATE OINTMENT is not recommended for use in patients suffering from severe liver problems. Consult your doctor before applying the medicine.
Allergy
Do not take SORVATE OINTMENT if you are allergic to Calcipotriol or any of the other ingredients of this medicine.
Others
SORVATE OINTMENT is not recommended for use if you:
- have history of hypersensitivity reactions (immune response to an allergen)
- have calcium metabolism disorders marked with high or low calcium levels.
- have signs of vitamin D toxicity such as nausea & vomiting, weakness, and frequent urination.
Before taking SORVATE OINTMENT, inform your doctor if you:
- smoke
- are undergoing ultraviolet light management
- have guttate, erythrodermic, exfoliative or pustular psoriasis
Use in Pediatrics:
SORVATE OINTMENT is not recommended for use in children (aged below 6 years). Consult your doctor before applying the medicine.
Use in Geriatrics:
SORVATE OINTMENT should be used with caution in elderly patient (aged above 65 years). Consult your doctor before taking.
Interactions
A. Drug - Drug interactions:
Inform your doctor about all the medicines you use, including prescription and non-prescription medicines, and herbal supplements.
Over dosage:
If you or anyone else applies too much of SORVATE OINTMENT or accidentally swallows it, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include elevated serum calcium levels with signs such as increased urinary frequency, excessive thirst, loss of appetite, dry/metallic taste in the mouth, stomach upsets.
Synopsis
| Drug | : | Calcipotriol |
| Pharmacological Category | : | Synthetic vitamin D3 derivative |
| Therapeutic Indication | : | Plaque Psoriasis |
| Dosage Forms | : | Ointment, Lotion |
More Information
- Keep SORVATE OINTMENT out of reach of children
- Store below 25°C
FAQs About SORVATE OINTMENT
Does SORVATE OINTMENT cause skin irritation?
Yes, SORVATE OINTMENT may cause skin irritation. Avoid harsh soaps and detergents, lotions, perfumed soaps and known allergy triggers that may help to soothe irritated skin. Consult your doctor before using.
Can I take other calcium supplements along with SORVATE OINTMENT?
As calcium supplements might increase calcium level in blood, consult your doctor before applying SORVATE OINTMENT to avoid excess production of calcium in blood which may occur with signs such as increased urinary frequency, excessive thirst, loss of appetite, dry/metallic taste in the mouth, stomach upsets.
How much dose of SORVATE OINTMENT can i use in a day?
Always apply SORVATE OINTMENT as directed by your physician. It is for external use only. Apply a thin layer of this medicine on the affected area. Managed areas on the face need not be covered with a plaster or bandage. Do not use this medicine on your face.
Can a patient undergoing UV light management apply SORVATE OINTMENT?
Yes, SORVATE OINTMENT can be used but with caution in patients undergoing ultraviolet light management since the medicine may get degraded upon exposure to ultraviolet resulting in reduced effect of the drug. Consult your doctor before applying the medicine.
References
1. K.D. Tripathi. Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page 891. [Accessed on 5th May 2022].
2. Luigi Naldi, Berthold Rzany. Psoriasis (chronic plaque). NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. January 2009. [Accessed on 5th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907770/
3. LEO Laboratories Ltd. U.S. Food and Drugs Administration (USFDA) [Revised in March 2015] [Accessed on 5th May 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/020273s013,020554s012lbl.pdf
4. Leo Laboratories Limited. Electronic Medicines Compendium (EMC) [Revised in November 2019] [Accessed on 5th May 2022] https://www.medicines.org.uk/emc/files/pil.981.pdf
5. Biocon Biologics India Limited. Calpsor Lotion. [Revised in August 2019] [Accessed on 5th May 2022] https://www.biocon.com/docs/domestic-market-pi/immuno/CALPSOR%20LOTION%20PI.pdf
Useful Diagnostic Tests
- Skin biopsy
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