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Introduction About SORIFIX OINTMENT
SORIFIX OINTMENT is a combination of Calcipotriol and Clobetasol which belongs to the group of medicines called Topical Corticosteroids. It is indicated for the topical management of plaque psoriasis. Plaque psoriasis (psoriasis vulgaris) is an autoimmune disease that causes cells to reproduce very quickly which causes thick, scaly patches called plaques on the skin.
SORIFIX OINTMENT is not recommended for use in patients with severe liver and kidney disease, skin atrophy, viral infections such as chicken pox or measles, skin infections and other skin diseases.
SORIFIX OINTMENT is intended for external use only. Managed areas need not be covered with a plaster or bandage. Avoid applying this medicine around your eyes, including eyelids. Do not apply SORIFIX OINTMENT on the face.
There are no adequate and well-controlled studies in pregnant women. Therefore, it should be used during pregnancy unless the potential benefit justifies the potential risk to the fetus. Consult your doctor before using SORIFIX OINTMENT. It should be used with caution in breastfeeding women. Consult your doctor before using it.
There is no clinical trial experience in children. Children may demonstrate greater susceptibility to systemic steroid related adverse effects due to a larger skin surface area to body weight ratio as compared to adults. Consult your doctor before using. SORIFIX OINTMENT should be used with caution in elder patients. The most common side effects of SORIFIX OINTMENT are skin irritation and mild aggravation of the disease. Consult your doctor if any of the above side effects worsen or persists for a long duration.
Uses Of SORIFIX OINTMENT
- Used to manage plaque psoriasis
How SORIFIX OINTMENT Works
SORIFIX OINTMENT works by managing psoriasis and its effects on the skin. Calcipotriol works by blocking the formation of new cells and manages accumulation of these cells. It plays a major role in managing psoriasis and helps body’s immunity to alter the cause of disease. Clobetasol belongs to corticosteroid helps in reducing inflammation by supressing the mediators responsible for it.
How to use SORIFIX OINTMENT
Apply SORIFIX OINTMENT as directed by your physician. It is for external use only. Apply a thin layer of this medicine on the affected area. Avoid applying this medicine around your eyes, including eyelids.
Side Effects Of SORIFIX OINTMENT
Common
- skin irritation
- mild aggravation of psoriasis
Warning & Precautions
Pregnancy
Consult your doctorThere are no adequate and well-controlled studies in pregnant women. Therefore, it should be used during pregnancy unless the potential benefit justifies the potential risk to the fetus. Consult your doctor before using SORIFIX OINTMENT.
Breastfeeding
Use with CautionSORIFIX OINTMENT should be used with caution in breastfeeding women. Consult your doctor before using.
Kidney
ContraindicatedSORIFIX OINTMENT is not recommended for patients with severe kidney disease. Consult your doctor before using it.
Liver
ContraindicatedSORIFIX OINTMENT is not recommended for patients with severe liver disease. Consult your doctor before using it.
Allergy
ContraindicatedDo not use SORIFIX OINTMENT if you are allergic to Calcipotriol or Clobetasol or any other ingredients of this medicine.
Lungs
ContraindicatedSORIFIX OINTMENT is not recommended for use in patients with skin manifestations in relation to tuberculosis. Consult your doctor before using it.
Others
SORIFIX OINTMENT is not recommended for use if you:
- have hypercalcemia or evidence of vitamin D toxicity
- have active viral illnesses such as chicken pox or measles
- have skin lesions
- have fungal, bacterial or skin infections
- have parasitic infections
- have skin manifestations in relation to syphilis
- have visible blood vessels on face
- have perioral dermatitis (reddish rash around mouth)
- have acne
- have skin thinning (skin atrophy)
- have striae atrophicae (stretch marks)
- have thinning of skin veins
- have ichthyosis (rough, dry scaly skin)
- have ulcers, wounds
- have itching in the genitals
- have other types of psoriasis (such as guttate, erythrodermic, exfoliative and pustular psoriasis)
Use in Pediatrics:
There is no clinical trial experience in children. Children may demonstrate greater susceptibility to systemic steroid related adverse effects due to a larger skin surface area to body weight ratio as compared to adults. Consult your doctor before using.
Use in Geriatrics:
SORIFIX OINTMENT should be used with caution in elder patients. Consult your doctor before using the medicine.
Interactions
A. Drug-Drug interactions:
Before using SORIFIX OINTMENT inform your doctor if you are taking or using any prescription, non-prescription and herbal supplements.
Overdosage:
If you or anyone else accidentally uses too much of SORIFIX OINTMENT, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Calcipotriol, Clobetasol |
| Pharmacological Category | : | Topical Corticosteroid |
| Therapeutic Indication | : | Plaque Psoriasis |
| Dosage Forms | : | Ointment, Lotion, Cream |
More Information
- Keep SORIFIX OINTMENT out of reach of children
- Store at room temperature
FAQs About SORIFIX OINTMENT
Q: What is SORIFIX OINTMENT used for?
A: It is a combination of Calcipotriol and Clobetasol which belongs to the group of medicines called Topical Corticosteroids. It is indicated for the topical management of plaque psoriasis.
Q: Can I use SORIFIX OINTMENT for wounds?
A: SORIFIX OINTMENT is not intended to manage wounds. Consult your doctor for advice before using this medicine.
Q: Can we use SORIFIX OINTMENT for children?
A: There is no clinical trial experience in children. Children may demonstrate greater susceptibility to systemic steroid related adverse effects due to a larger skin surface area to body weight ratio as compared to adults. Consult your doctor before using.
Q: Can I use SORIFIX OINTMENT on my face for face brightening?
A: SORIFIX OINTMENT is not intended for beauty purposes. Consult your doctor before using the medicine.
Q: Will over usage of SORIFIX OINTMENT cause any harmful side effects?
A: Long term over usage of this medicine can cause some systemic effects such as suppression of pituitary adrenal function, resulting in secondary adrenal insufficiency. Consult your doctor for advice.
Q: I already have a skin infection can I use SORIFIX OINTMENT along with my regular medications to manage the infection?
A: No, do not use SORIFIX OINTMENT without consulting your doctor. It is intended to manage bacterial infections only. Avoid using it for other infections as it may cause other serious effects.
Q: How should I use SORIFIX OINTMENT?
A: Always apply SORIFIX OINTMENT as directed by your physician. It is for external use only. Apply a thin layer of this medicine on the affected area. Managed areas on the face need not be covered with a plaster or bandage. Do not use this medicine on your face for more than 5 days. Avoid applying this medicine around your eyes, including eyelids.
References
1. K.D. Tripathi Drugs Acting on Skin and Mucous Membranes, Drugs Affecting Calcium Balance Essentials of Pharmacology seventh edition2013 Page no: 895, 343.
2. Norito Katoh Saburo Kishimoto Combination of calcipotriol and clobetasol propionate as a premixed ointment for the treatment of psoriasis July 2003. Research Gate article. [Accessed on 31st May 2022] https://www.researchgate.net/publication/10588522_Combination_of_calcipotriol_and_clobetasol_propionate_as_a_premixed_ointment_for_the_treatment_of_psoriasis
3. Biocon Biologics India Limited Calcipotriol 0.005% w/v and Clobetasol Propionate 0.05% w/v Solution. [Revised on August 2019] [Accessed on 31st May 2022] https://www.biocon.com/docs/prescribing_information/immunotherapy/calpsorc_pi.pdf
4. Biocon Limited Calcipotriol 0.005% w/w & Clobetasol Propionate 0.05% w/w Ointment. [Accessed on 31st May 2022] https://www.biocon.com/docs/prescribing_information/immunotherapy/calpsorc_pi.pdf
5. Lee ford Calcipotriol 0.005% & Clobetasol Propionate 0.05% w/w. [Accessed on 31st May 2022] https://www.leeford.in/product/1464/soraherb-ointment
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